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Paul Matteis

Paul Matteis Analyst Performance

Managing Director, Head of Therapeutics Research Biotechnology at Stifel Nicolaus

Paul Matteis is a stock analyst at Stifel Nicolaus focused in the healthcare sector, covering 29 publicly traded companies. Over the past year, Paul Matteis has issued 47 stock ratings, including buy and hold recommendations. While full access to Paul Matteis' proprietary MarketBeat Analyst Ranking is reserved for MarketBeat All Access subscribers, the rating is updated daily to reflect the most recent analyst activity. This profile highlights Paul Matteis' coverage history, rating activity, and performance tendencies - helping individual investors make more informed trading decisions.

Analyst Rankings, Coverage, and Performance Statistics

Average Return
00.00% 12-Month ROI
Success Rate
00.00% Profitable Ratings
Total Ratings
95 Last 11 Years
Buy Recommendations
76.47% 65 Buy Ratings
Companies Covered
29 Unique Companies

Ratings Distribution

RatingPercentageCount
Strong Buy0.0%0 ratings
Buy76.5%65 ratings
Hold23.5%20 ratings
Sell0.0%0 ratings

Out of 85 total stock ratings issued by Paul Matteis at Stifel Nicolaus, the majority (76.5%) have been Buy recommendations, followed by 23.5% Hold.

Exchange Coverage

ExchangePercentageCount
NASDAQ
100.0% of companies on NASDAQ
29 companies

Paul Matteis, an analyst at Stifel Nicolaus, currently covers 29 companies listed on , with the majority traded on NASDAQ.

Coverage Focus

Sector IconSectorPercentage
Healthcare
28 companies
96.6%
Miscellaneous
1 company
3.4%

Paul Matteis of Stifel Nicolaus specializes in stock coverage within the Healthcare sector, with additional focus on companies.

Coverage Industries

IndustryPercentage
BIOTECHNOLOGY
17 companies
58.6%
PHARMACEUTICALS
11 companies
37.9%
Miscellaneous
1 company
3.4%

About Paul Matteis

Paul Matteis joined Stifel in 2018. Based out of the firm’s Boston office, he serves as a Managing Director and Head of Biotech Research. Previously, Paul was a Senior Biotechnology Analyst covering small-cap and mid-cap companies at Leerink, with a focus on neuroscience, central nervous system and rare disease. Before this, he was a Research Assistant at the Harvard Division of Sleep Medicine at Brigham & Women’s Hospital. Paul was named a “Runner Up” in Small/Mid Cap Biotechnology in 2019-2024, as well as a “Rising Star” by Institutional Investor in both 2015 and 2016, as part of the publication’s All-America Research Team rankings. He attended Skidmore College in New York, where he studied Psychology and Pre-Medical Sciences and graduated Phi Beta Kappa.
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Paul Matteis' Ratings History at Stifel Nicolaus

Recommendation ROI is the percentage between the price on the Report Date to the price 12 months after the report date.
Available with a MarketBeat All Access Subscription
12-Month ROIUpgrade to All Access to use the All ROI Filter
CompanyReport DateActionReport Date Price12-Month
Price Target
Rating12-Month
Price & ROI
Details
Cyclerion Therapeutics, Inc. stock logo
KRSA
Cyclerion Therapeutics
9/14/2026Initiated Coverage$30.65$43.00Buy
Biogen Inc. stock logo
BIIB
Biogen
9/10/2026Set Price Target$214.77$242.00
LB Pharmaceuticals Inc stock logo
LBRX
LB Pharmaceuticals
8/13/2026Set Price Target$44.87$53.00
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
8/10/2026Reiterated Rating$4.19$7.00Hold
Neurocrine Biosciences, Inc. stock logo
NBIX
Neurocrine Biosciences
7/31/2026Boost Price Target$165.52$215.00Buy
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
7/31/2026Lower Price Target$203.36$318.00Buy
ACADIA Pharmaceuticals Inc. stock logo
ACAD
ACADIA Pharmaceuticals
7/21/2026Boost Price Target$25.09$25.00Hold
Alkermes plc stock logo
ALKS
Alkermes
7/20/2026Reiterated Rating$52.72$63.00Buy
Definium Therapeutics, Inc. stock logo
DFTX
Definium Therapeutics
7/8/2026Boost Price Target$44.48$60.00Buy
Compass Pathways PLC Sponsored ADR stock logo
CMPS
Compass Pathways
7/7/2026Boost Price Target$12.99$21.00Buy
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
6/15/2026Set Price Target$94.11$133.00
Maplight Therapeutics, Inc. stock logo
MPLT
Maplight Therapeutics
6/1/2026Boost Price Target$29.76$36.00Buy
Seaport Therapeutics, Inc. stock logo
SPTX
Seaport Therapeutics
5/26/2026Initiated Coverage$17.50$30.00Buy
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
5/18/2026Boost Price Target$40.22$55.00Buy
uniQure N.V. stock logo
QURE
uniQure
5/5/2026Set Price Target$20.66$28.00
Definium Therapeutics, Inc. stock logo
DFTX
Definium Therapeutics
4/16/2026Set Price Target$22.46$30.00Buy
Immunic, Inc. stock logo
IMUX
Immunic
4/16/2026Set Price Target$10.00$25.00Buy
LB Pharmaceuticals Inc stock logo
LBRX
LB Pharmaceuticals
3/27/2026Boost Price Target$24.16$40.00Buy
KalVista Pharmaceuticals, Inc. stock logo
KALV
KalVista Pharmaceuticals
3/26/2026Boost Price Target$17.49$42.00Buy
uniQure N.V. stock logo
QURE
uniQure
3/2/2026Set Price Target$10.49$14.00
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
2/26/2026Set Price Target$98.96$131.00
ACADIA Pharmaceuticals Inc. stock logo
ACAD
ACADIA Pharmaceuticals
2/26/2026Lower Price Target$25.05$24.00Hold
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
2/26/2026Boost Price Target$81.57$77.00Hold
BioMarin Pharmaceutical Inc. stock logo
BMRN
BioMarin Pharmaceutical
2/24/2026Set Price Target$63.53$68.00
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
2/13/2026Boost Price Target$465.02$466.00Hold
Biogen Inc. stock logo
BIIB
Biogen
2/6/2026Boost Price Target$201.18$214.00Buy
VistaGen Therapeutics, Inc. stock logo
VTGN
VistaGen Therapeutics
12/17/2025Downgrade$0.79$1.00Hold
ACADIA Pharmaceuticals Inc. stock logo
ACAD
ACADIA Pharmaceuticals
12/16/2025Set Price Target$27.26$37.00
uniQure N.V. stock logo
QURE
uniQure
12/11/2025Lower Price Target$20.14$40.00Buy
Neurocrine Biosciences, Inc. stock logo
NBIX
Neurocrine Biosciences
12/11/2025Boost Price Target$155.63$188.00Buy
LB Pharmaceuticals Inc stock logo
LBRX
LB Pharmaceuticals
12/11/2025Boost Price Target$21.36$35.00Buy
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
12/11/2025Boost Price Target$19.69$39.00Buy
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
12/11/2025Boost Price Target$404.46$508.00Buy
ACADIA Pharmaceuticals Inc. stock logo
ACAD
ACADIA Pharmaceuticals
12/11/2025Boost Price Target$26.81$25.00Hold
Maplight Therapeutics, Inc. stock logo
MPLT
Maplight Therapeutics
11/21/2025Initiated Coverage$13.29$28.00Buy
VistaGen Therapeutics, Inc. stock logo
VTGN
VistaGen Therapeutics
11/17/2025Set Price Target$4.60$12.00
Neumora Therapeutics, Inc. stock logo
NMRA
Neumora Therapeutics
11/17/2025Boost Price Target$2.65$3.00Hold
BioMarin Pharmaceutical Inc. stock logo
BMRN
BioMarin Pharmaceutical
11/6/2025Reiterated Rating$52.80$61.00Hold
Biogen Inc. stock logo
BIIB
Biogen
11/6/2025Upgrade$153.43$202.00Buy
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
11/4/2025Lower Price Target$426.00$445.00Hold
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Neurocrine Biosciences, Inc. stock logo
NBIX
Neurocrine Biosciences
10/29/2025Boost Price Target$139.82$183.00Buy
BioMarin Pharmaceutical Inc. stock logo
BMRN
BioMarin Pharmaceutical
10/28/2025Lower Price Target$54.17$73.00Buy
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
10/6/2025Boost Price Target$69.15$67.00Hold
LB Pharmaceuticals Inc stock logo
LBRX
LB Pharmaceuticals
10/6/2025Initiated Coverage$15.05$27.00Buy
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
10/6/2025Boost Price Target$456.35$495.00Buy
PepGen, Inc. stock logo
PEPG
PepGen
9/25/2025Boost Price Target$5.87$12.00Buy
uniQure N.V. stock logo
QURE
uniQure
9/24/2025Boost Price Target$46.06$65.00Buy
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
8/5/2025Lower Price Target$472.27$455.00Hold
Neurocrine Biosciences, Inc. stock logo
NBIX
Neurocrine Biosciences
7/31/2025Boost Price Target$131.49$174.00Buy
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
7/31/2025Lower Price Target$9.90$36.00Buy
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
5/29/2025Boost Price Target$62.66$94.00Buy
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
3/31/2025Boost Price Target$268.46$345.00Buy
Neumora Therapeutics, Inc. stock logo
NMRA
Neumora Therapeutics
3/7/2025Downgrade$1.52$2.00Hold
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
3/5/2025Initiated Coverage$54.02$78.00Buy
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
3/4/2025Initiated Coverage$14.41$32.00Buy
Compass Pathways PLC Sponsored ADR stock logo
CMPS
Compass Pathways
2/27/2025Initiated Coverage$3.70$11.00Buy
GH Research PLC stock logo
GHRS
GH Research
2/27/2025Boost Price Target$10.82$32.00Buy