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Neurogene (NGNE) Competitors

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$20.30 +0.81 (+4.13%)
As of 11:35 AM Eastern
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NGNE vs. SYRE, MLYS, AVDL, PHVS, NRIX, ARDX, ORIC, PRAX, ZYME, and LENZ

Should you be buying Neurogene stock or one of its competitors? The main competitors of Neurogene include Spyre Therapeutics (SYRE), Mineralys Therapeutics (MLYS), Avadel Pharmaceuticals (AVDL), Pharvaris (PHVS), Nurix Therapeutics (NRIX), Ardelyx (ARDX), Oric Pharmaceuticals (ORIC), Praxis Precision Medicines (PRAX), Zymeworks (ZYME), and LENZ Therapeutics (LENZ). These companies are all part of the "pharmaceutical products" industry.

Neurogene vs. Its Competitors

Neurogene (NASDAQ:NGNE) and Spyre Therapeutics (NASDAQ:SYRE) are both small-cap medical companies, but which is the superior stock? We will contrast the two businesses based on the strength of their profitability, institutional ownership, risk, valuation, analyst recommendations, media sentiment, dividends and earnings.

52.4% of Neurogene shares are held by institutional investors. Comparatively, 80.4% of Spyre Therapeutics shares are held by institutional investors. 11.6% of Neurogene shares are held by insiders. Comparatively, 6.2% of Spyre Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Neurogene currently has a consensus target price of $46.17, suggesting a potential upside of 127.37%. Spyre Therapeutics has a consensus target price of $53.40, suggesting a potential upside of 244.61%. Given Spyre Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Spyre Therapeutics is more favorable than Neurogene.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Neurogene
0 Sell rating(s)
2 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.75
Spyre Therapeutics
0 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
2 Strong Buy rating(s)
3.25

Neurogene has a beta of 1.51, meaning that its stock price is 51% more volatile than the S&P 500. Comparatively, Spyre Therapeutics has a beta of 2.68, meaning that its stock price is 168% more volatile than the S&P 500.

Neurogene has higher revenue and earnings than Spyre Therapeutics. Neurogene is trading at a lower price-to-earnings ratio than Spyre Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Neurogene$925K313.07-$75.14M-$4.35-4.67
Spyre Therapeutics$890K1,049.55-$208.02M-$3.77-4.11

In the previous week, Neurogene had 6 more articles in the media than Spyre Therapeutics. MarketBeat recorded 8 mentions for Neurogene and 2 mentions for Spyre Therapeutics. Neurogene's average media sentiment score of 0.18 beat Spyre Therapeutics' score of 0.00 indicating that Neurogene is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Neurogene
1 Very Positive mention(s)
2 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Spyre Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Neurogene's return on equity of -36.16% beat Spyre Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
NeurogeneN/A -36.16% -32.51%
Spyre Therapeutics N/A -77.46%-41.06%

Summary

Spyre Therapeutics beats Neurogene on 8 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding NGNE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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NGNE vs. The Competition

MetricNeurogeneMED IndustryMedical SectorNASDAQ Exchange
Market Cap$290.77M$2.90B$5.50B$8.92B
Dividend YieldN/A2.44%5.24%4.05%
P/E Ratio-4.6920.8727.1720.13
Price / Sales313.07190.94376.8992.89
Price / CashN/A41.7026.2128.59
Price / Book0.977.447.985.60
Net Income-$75.14M-$55.04M$3.17B$248.49M
7 Day Performance5.81%4.41%3.04%5.85%
1 Month Performance-6.99%1.58%2.38%7.54%
1 Year Performance-44.81%4.62%33.64%20.66%

Neurogene Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
NGNE
Neurogene
3.7731 of 5 stars
$20.31
+4.1%
$46.17
+127.4%
-42.9%$290.77M$925K-4.6990
SYRE
Spyre Therapeutics
1.3354 of 5 stars
$14.97
-1.6%
$53.40
+256.7%
-40.0%$917.39M$890K-3.9773
MLYS
Mineralys Therapeutics
2.141 of 5 stars
$13.53
-1.3%
$32.25
+138.4%
+8.8%$893.55MN/A-3.6328
AVDL
Avadel Pharmaceuticals
2.435 of 5 stars
$8.85
-3.8%
$18.17
+105.3%
-39.9%$890M$169.12M-32.7870
PHVS
Pharvaris
1.7646 of 5 stars
$17.60
+3.5%
$36.20
+105.7%
+8.1%$888.93MN/A-5.8530
NRIX
Nurix Therapeutics
1.6172 of 5 stars
$11.39
-2.1%
$30.18
+164.9%
-36.5%$887.38M$54.55M-4.07300Upcoming Earnings
ARDX
Ardelyx
4.4329 of 5 stars
$3.92
+6.2%
$10.89
+177.8%
-17.8%$882.85M$333.61M-17.8290
ORIC
Oric Pharmaceuticals
4.6225 of 5 stars
$10.15
-1.6%
$19.17
+88.8%
+38.5%$878.66MN/A-5.4380Analyst Forecast
PRAX
Praxis Precision Medicines
2.9379 of 5 stars
$42.05
-2.2%
$109.90
+161.4%
+15.8%$875.87M$8.55M-3.92110
ZYME
Zymeworks
2.0675 of 5 stars
$12.55
+0.6%
$21.00
+67.3%
+47.3%$873.19M$93.38M-8.37460
LENZ
LENZ Therapeutics
1.3351 of 5 stars
$29.31
-2.9%
$46.60
+59.0%
+74.4%$849.45MN/A-16.56110

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This page (NASDAQ:NGNE) was last updated on 7/8/2025 by MarketBeat.com Staff
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