NASDAQ:GYRE Gyre Therapeutics (GYRE) Stock Price, News & Analysis $6.06 0.00 (0.00%) Closing price 05/22/2026 04:00 PM EasternExtended Trading$6.07 +0.01 (+0.17%) As of 05/22/2026 05:23 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Gyre Therapeutics Stock (NASDAQ:GYRE) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Gyre Therapeutics alerts:Sign Up Key Stats Today's Range$6.01▼$6.2750-Day Range$6.04▼$8.1052-Week Range$5.97▼$11.61Volume86,973 shsAverage Volume79,471 shsMarket Capitalization$588.00 millionP/E RatioN/ADividend YieldN/APrice Target$17.00Consensus RatingHold Company Overview Gyre Therapeutics, Inc. is a clinical-stage biotechnology company focused on discovering and developing small-molecule therapies that target lipid biology to treat a range of metabolic, inflammatory and neurodegenerative diseases. The company’s proprietary platform combines lipidomic profiling with drug discovery tools to identify compounds that selectively modulate membrane lipid composition and restore normal protein function in disease-relevant cells. Gyre’s preclinical pipeline includes programs in nonalcoholic steatohepatitis (NASH), Alzheimer’s disease and autoimmune conditions, reflecting its strategy of applying a unified lipid-targeted approach across multiple therapeutic areas. By leveraging its platform to validate novel targets and generate lead candidates, the company aims to address unmet medical needs where dysregulated lipid environments drive disease progression. Headquartered in South San Francisco, California, Gyre Therapeutics was founded in 2021 and completed its initial public offering on the Nasdaq Global Market under the ticker symbol GYRE in mid-2023. Operating primarily in the United States, the company collaborates with academic researchers and industry partners to advance its discovery efforts. Through its innovative focus on membrane biochemistry, Gyre seeks to build a diversified portfolio of first-in-class small-molecule therapies.AI Generated. May Contain Errors. Read More Gyre Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks44th Percentile Overall ScoreGYRE MarketRank™: Gyre Therapeutics scored higher than 44% of companies evaluated by MarketBeat, and ranked 602nd out of 867 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.4 / 5Analyst RatingHold Consensus RatingGyre Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.00, and is based on no strong buy ratings, 2 buy ratings, no hold ratings, and 2 sell ratings.Upside PotentialGyre Therapeutics has a consensus price target of $17.00, representing about 180.5% upside from its current price of $6.06.Amount of Analyst CoverageGyre Therapeutics has only been the subject of 2 research reports in the past 90 days.Read more about Gyre Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Gyre Therapeutics are expected to grow in the coming year, from ($0.30) to ($0.20) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Gyre Therapeutics is -67.33, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Gyre Therapeutics is -67.33, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioGyre Therapeutics has a P/B Ratio of 4.30. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Gyre Therapeutics' valuation and earnings. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted1.81% of the float of Gyre Therapeutics has been sold short.Short Interest Ratio / Days to CoverGyre Therapeutics has a short interest ratio ("days to cover") of 32.58, which indicates bearish sentiment.Change versus previous monthShort interest in Gyre Therapeutics has recently decreased by 0.24%, indicating that investor sentiment is improving. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldGyre Therapeutics does not currently pay a dividend.Dividend GrowthGyre Therapeutics does not have a long track record of dividend growth. News and Social Media1.6 / 5News Sentiment-0.39 News SentimentGyre Therapeutics has a news sentiment score of -0.39. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.47 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 6 news articles for Gyre Therapeutics this week, compared to 2 articles on an average week.Search InterestOnly 1 people have searched for GYRE on MarketBeat in the last 30 days. This is a decrease of -50% compared to the previous 30 days.MarketBeat Follows1 people have added Gyre Therapeutics to their MarketBeat watchlist in the last 30 days. Company Ownership1.4 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Gyre Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $219,580.00 in company stock.Percentage Held by Insiders10.00% of the stock of Gyre Therapeutics is held by insiders.Percentage Held by Institutions23.99% of the stock of Gyre Therapeutics is held by institutions.Read more about Gyre Therapeutics' insider trading history. Receive GYRE Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Gyre Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. GYRE Stock News HeadlinesGyre Therapeutics (NASDAQ:GYRE) COO Sells $57,810.00 in StockMay 25 at 4:58 AM | americanbankingnews.comGyre Therapeutics (NASDAQ:GYRE) COO Sells $78,843.00 in StockMay 25 at 4:58 AM | americanbankingnews.comTrump's New DollarPorter Stansberry says President Trump has signed an executive order initiating what he calls a full U.S. dollar reset - and most Americans don't know it's happening. The last time America underwent a monetary shift like this, under Nixon in the 1970s, it minted an average of 1,300 new millionaires a day for over half a century. Stansberry has released a new documentary naming the assets he believes are positioned to surge as a result. | Porter & Company (Ad)Gyre Therapeutics (NASDAQ:GYRE) COO Weiguo Ye Sells 9,400 SharesMay 23 at 8:55 AM | insidertrades.comGyre Therapeutics (NASDAQ:GYRE) Hits New 12-Month Low - Here's WhyMay 21, 2026 | americanbankingnews.comFinancial Survey: Immuron (NASDAQ:IMRN) & Gyre Therapeutics (NASDAQ:GYRE)May 18, 2026 | americanbankingnews.comGyre Therapeutics (NASDAQ:GYRE) Lowered to "Sell" Rating by Wall Street ZenMay 16, 2026 | americanbankingnews.comGyre Therapeutics Announces NMPA Acceptance of New Drug Application for F351 (hydronidone) for CHB-Induced Liver Fibrosis TreatmentMay 12, 2026 | globenewswire.comSee More Headlines GYRE Stock Analysis - Frequently Asked Questions How have GYRE shares performed this year? Gyre Therapeutics' stock was trading at $7.06 at the start of the year. Since then, GYRE shares have decreased by 14.2% and is now trading at $6.06. How were Gyre Therapeutics' earnings last quarter? Gyre Therapeutics, Inc. (NASDAQ:GYRE) issued its earnings results on Thursday, March, 12th. The company reported $0.04 earnings per share for the quarter, missing analysts' consensus estimates of $0.08 by $0.04. The business earned $37.20 million during the quarter, compared to the consensus estimate of $36.30 million. Gyre Therapeutics had a positive trailing twelve-month return on equity of 3.13% and a negative net margin of 5.44%. Who are Gyre Therapeutics' major shareholders? Top institutional shareholders of Gyre Therapeutics include Bank of New York Mellon Corp (0.04%), Dimensional Fund Advisors LP (0.03%) and Royal Bank of Canada (0.01%). Insiders that own company stock include Songjiang Ma, Ying Luo, Weiguo Ye and Nassim Usman. View institutional ownership trends. How do I buy shares of Gyre Therapeutics? Shares of GYRE stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Gyre Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Gyre Therapeutics investors own include NVIDIA (NVDA), Meta Platforms (META), Advanced Micro Devices (AMD), Netflix (NFLX), Broadcom (AVGO), Palo Alto Networks (PANW) and Invesco QQQ (QQQ). Company Calendar Last Earnings3/12/2026Today5/26/2026Next Earnings (Estimated)8/10/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Red Zone (14m+) 1-Year History May 25 Aug 25 Nov 25 Feb 26 May 26 GYRE's financial health is in the Red zone, according to TradeSmith. GYRE has been in this zone for over 14 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:GYRE Previous SymbolNASDAQ:GYRE CIK1124105 Webwww.catalystbiosciences.com Phone(619) 949-3681Fax336-480-2107Employees40Year FoundedN/APrice Target and Rating Average Price Target for Gyre Therapeutics$17.00 High Price Target$18.00 Low Price Target$16.00 Potential Upside/Downside+180.5%Consensus RatingHold Rating Score (0-4)2.00 Research Coverage4 Analysts Profitability EPS (Trailing Twelve Months)($0.09) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income$5.03 million Net Margins-5.44% Pretax Margin0.48% Return on Equity3.13% Return on Assets2.67% Debt Debt-to-Equity RatioN/A Current Ratio4.64 Quick Ratio4.06 Sales & Book Value Annual Sales$116.59 million Price / Sales5.04 Cash Flow$0.22 per share Price / Cash Flow27.27 Book Value$1.41 per share Price / Book4.30Miscellaneous Outstanding Shares97,030,000Free Float87,325,000Market Cap$588.00 million OptionableNo Data Beta2.03 Options Trading Made Easy - Download NowLearn the basics of options trading and how to use them to boost returns and manage risk with this free report from MarketBeat. 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