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4D Molecular Therapeutics (FDMT) Competitors

4D Molecular Therapeutics logo
$15.83 -0.27 (-1.68%)
As of 08/21/2026 04:00 PM Eastern

FDMT vs. VRDN, BCRX, NKTR, AMLX, and KLRA

Should you buy 4D Molecular Therapeutics stock or one of its competitors? 4D Molecular Therapeutics's main competitors and comparable companies include Viridian Therapeutics (VRDN), BioCryst Pharmaceuticals (BCRX), Nektar Therapeutics (NKTR), Amylyx Pharmaceuticals (AMLX), and Kailera Therapeutics (KLRA). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does 4D Molecular Therapeutics compare to Viridian Therapeutics?

4D Molecular Therapeutics (NASDAQ:FDMT) and Viridian Therapeutics (NASDAQ:VRDN) are both healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their valuation, analyst recommendations, risk, earnings, media sentiment, institutional ownership, profitability and dividends.

4D Molecular Therapeutics presently has a consensus price target of $29.63, suggesting a potential upside of 87.14%. Viridian Therapeutics has a consensus price target of $38.93, suggesting a potential upside of 60.27%. Given 4D Molecular Therapeutics' higher possible upside, equities analysts clearly believe 4D Molecular Therapeutics is more favorable than Viridian Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
4D Molecular Therapeutics
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80
Viridian Therapeutics
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.86

4D Molecular Therapeutics has a beta of 2.73, meaning that its stock price is 173% more volatile than the broader market. Comparatively, Viridian Therapeutics has a beta of 0.91, meaning that its stock price is 9% less volatile than the broader market.

99.3% of 4D Molecular Therapeutics shares are held by institutional investors. 7.9% of 4D Molecular Therapeutics shares are held by company insiders. Comparatively, 2.4% of Viridian Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

4D Molecular Therapeutics has a net margin of -194.74% compared to Viridian Therapeutics' net margin of -505.86%. 4D Molecular Therapeutics' return on equity of -41.33% beat Viridian Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
4D Molecular Therapeutics-194.74% -41.33% -35.90%
Viridian Therapeutics -505.86%-72.97%-42.80%

In the previous week, 4D Molecular Therapeutics had 7 more articles in the media than Viridian Therapeutics. MarketBeat recorded 17 mentions for 4D Molecular Therapeutics and 10 mentions for Viridian Therapeutics. Viridian Therapeutics' average media sentiment score of 1.04 beat 4D Molecular Therapeutics' score of 0.53 indicating that Viridian Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
4D Molecular Therapeutics
7 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Viridian Therapeutics
8 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

4D Molecular Therapeutics has higher revenue and earnings than Viridian Therapeutics. Viridian Therapeutics is trading at a lower price-to-earnings ratio than 4D Molecular Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
4D Molecular Therapeutics$85.21M10.26-$140.11M-$2.63N/A
Viridian Therapeutics$70.85M38.84-$342.60M-$3.37N/A

Summary

4D Molecular Therapeutics beats Viridian Therapeutics on 13 of the 17 factors compared between the two stocks.

How does 4D Molecular Therapeutics compare to BioCryst Pharmaceuticals?

4D Molecular Therapeutics (NASDAQ:FDMT) and BioCryst Pharmaceuticals (NASDAQ:BCRX) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their valuation, risk, earnings, institutional ownership, media sentiment, analyst recommendations, profitability and dividends.

99.3% of 4D Molecular Therapeutics shares are held by institutional investors. Comparatively, 85.9% of BioCryst Pharmaceuticals shares are held by institutional investors. 7.9% of 4D Molecular Therapeutics shares are held by insiders. Comparatively, 3.8% of BioCryst Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

BioCryst Pharmaceuticals has a net margin of -40.90% compared to 4D Molecular Therapeutics' net margin of -194.74%. 4D Molecular Therapeutics' return on equity of -41.33% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
4D Molecular Therapeutics-194.74% -41.33% -35.90%
BioCryst Pharmaceuticals -40.90%-86.89%66.37%

4D Molecular Therapeutics has a beta of 2.73, indicating that its share price is 173% more volatile than the broader market. Comparatively, BioCryst Pharmaceuticals has a beta of 0.55, indicating that its share price is 45% less volatile than the broader market.

4D Molecular Therapeutics presently has a consensus target price of $29.63, suggesting a potential upside of 87.14%. BioCryst Pharmaceuticals has a consensus target price of $20.60, suggesting a potential upside of 115.48%. Given BioCryst Pharmaceuticals' higher probable upside, analysts clearly believe BioCryst Pharmaceuticals is more favorable than 4D Molecular Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
4D Molecular Therapeutics
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80
BioCryst Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.67

BioCryst Pharmaceuticals has higher revenue and earnings than 4D Molecular Therapeutics. BioCryst Pharmaceuticals is trading at a lower price-to-earnings ratio than 4D Molecular Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
4D Molecular Therapeutics$85.21M10.26-$140.11M-$2.63N/A
BioCryst Pharmaceuticals$940.61M2.60$263.86M-$1.50N/A

In the previous week, 4D Molecular Therapeutics had 10 more articles in the media than BioCryst Pharmaceuticals. MarketBeat recorded 17 mentions for 4D Molecular Therapeutics and 7 mentions for BioCryst Pharmaceuticals. BioCryst Pharmaceuticals' average media sentiment score of 0.95 beat 4D Molecular Therapeutics' score of 0.53 indicating that BioCryst Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
4D Molecular Therapeutics
7 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
BioCryst Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

4D Molecular Therapeutics beats BioCryst Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does 4D Molecular Therapeutics compare to Nektar Therapeutics?

4D Molecular Therapeutics (NASDAQ:FDMT) and Nektar Therapeutics (NASDAQ:NKTR) are both healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their dividends, earnings, profitability, valuation, risk, media sentiment, analyst recommendations and institutional ownership.

4D Molecular Therapeutics currently has a consensus price target of $29.63, indicating a potential upside of 87.14%. Nektar Therapeutics has a consensus price target of $141.50, indicating a potential upside of 91.16%. Given Nektar Therapeutics' higher probable upside, analysts clearly believe Nektar Therapeutics is more favorable than 4D Molecular Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
4D Molecular Therapeutics
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80
Nektar Therapeutics
1 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.69

99.3% of 4D Molecular Therapeutics shares are owned by institutional investors. Comparatively, 75.9% of Nektar Therapeutics shares are owned by institutional investors. 7.9% of 4D Molecular Therapeutics shares are owned by company insiders. Comparatively, 2.5% of Nektar Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

4D Molecular Therapeutics has a net margin of -194.74% compared to Nektar Therapeutics' net margin of -287.84%. Nektar Therapeutics' return on equity of -37.87% beat 4D Molecular Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
4D Molecular Therapeutics-194.74% -41.33% -35.90%
Nektar Therapeutics -287.84%-37.87%-25.67%

4D Molecular Therapeutics has a beta of 2.73, meaning that its share price is 173% more volatile than the broader market. Comparatively, Nektar Therapeutics has a beta of 1.14, meaning that its share price is 14% more volatile than the broader market.

4D Molecular Therapeutics has higher revenue and earnings than Nektar Therapeutics. Nektar Therapeutics is trading at a lower price-to-earnings ratio than 4D Molecular Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
4D Molecular Therapeutics$85.21M10.26-$140.11M-$2.63N/A
Nektar Therapeutics$55.23M45.75-$164.08M-$6.70N/A

In the previous week, Nektar Therapeutics had 5 more articles in the media than 4D Molecular Therapeutics. MarketBeat recorded 22 mentions for Nektar Therapeutics and 17 mentions for 4D Molecular Therapeutics. 4D Molecular Therapeutics' average media sentiment score of 0.53 beat Nektar Therapeutics' score of 0.44 indicating that 4D Molecular Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
4D Molecular Therapeutics
7 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Nektar Therapeutics
3 Very Positive mention(s)
3 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Summary

4D Molecular Therapeutics beats Nektar Therapeutics on 11 of the 17 factors compared between the two stocks.

How does 4D Molecular Therapeutics compare to Amylyx Pharmaceuticals?

Amylyx Pharmaceuticals (NASDAQ:AMLX) and 4D Molecular Therapeutics (NASDAQ:FDMT) are both healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their institutional ownership, earnings, risk, profitability, valuation, analyst recommendations, media sentiment and dividends.

Amylyx Pharmaceuticals has a net margin of 0.00% compared to 4D Molecular Therapeutics' net margin of -194.74%. 4D Molecular Therapeutics' return on equity of -41.33% beat Amylyx Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Amylyx PharmaceuticalsN/A -52.92% -48.53%
4D Molecular Therapeutics -194.74%-41.33%-35.90%

4D Molecular Therapeutics has lower revenue, but higher earnings than Amylyx Pharmaceuticals. Amylyx Pharmaceuticals is trading at a lower price-to-earnings ratio than 4D Molecular Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Amylyx Pharmaceuticals$87.37M49.30-$144.74M-$1.43N/A
4D Molecular Therapeutics$85.21M10.26-$140.11M-$2.63N/A

Amylyx Pharmaceuticals has a beta of -0.21, suggesting that its stock price is 121% less volatile than the broader market. Comparatively, 4D Molecular Therapeutics has a beta of 2.73, suggesting that its stock price is 173% more volatile than the broader market.

Amylyx Pharmaceuticals currently has a consensus price target of $36.25, indicating a potential downside of 6.23%. 4D Molecular Therapeutics has a consensus price target of $29.63, indicating a potential upside of 87.14%. Given 4D Molecular Therapeutics' higher probable upside, analysts plainly believe 4D Molecular Therapeutics is more favorable than Amylyx Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Amylyx Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00
4D Molecular Therapeutics
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80

In the previous week, Amylyx Pharmaceuticals had 25 more articles in the media than 4D Molecular Therapeutics. MarketBeat recorded 42 mentions for Amylyx Pharmaceuticals and 17 mentions for 4D Molecular Therapeutics. Amylyx Pharmaceuticals' average media sentiment score of 0.71 beat 4D Molecular Therapeutics' score of 0.53 indicating that Amylyx Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Amylyx Pharmaceuticals
14 Very Positive mention(s)
7 Positive mention(s)
12 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
4D Molecular Therapeutics
7 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

95.8% of Amylyx Pharmaceuticals shares are owned by institutional investors. Comparatively, 99.3% of 4D Molecular Therapeutics shares are owned by institutional investors. 10.9% of Amylyx Pharmaceuticals shares are owned by insiders. Comparatively, 7.9% of 4D Molecular Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Summary

Amylyx Pharmaceuticals beats 4D Molecular Therapeutics on 10 of the 17 factors compared between the two stocks.

How does 4D Molecular Therapeutics compare to Kailera Therapeutics?

4D Molecular Therapeutics (NASDAQ:FDMT) and Kailera Therapeutics (NASDAQ:KLRA) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their profitability, media sentiment, valuation, dividends, institutional ownership, earnings, risk and analyst recommendations.

99.3% of 4D Molecular Therapeutics shares are held by institutional investors. 7.9% of 4D Molecular Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Kailera Therapeutics has a net margin of 0.00% compared to 4D Molecular Therapeutics' net margin of -194.74%. Kailera Therapeutics' return on equity of 0.00% beat 4D Molecular Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
4D Molecular Therapeutics-194.74% -41.33% -35.90%
Kailera Therapeutics N/A N/A N/A

4D Molecular Therapeutics has higher revenue and earnings than Kailera Therapeutics. 4D Molecular Therapeutics is trading at a lower price-to-earnings ratio than Kailera Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
4D Molecular Therapeutics$85.21M10.26-$140.11M-$2.63N/A
Kailera TherapeuticsN/AN/A-$148.96M-$3.65 thousandN/A

In the previous week, 4D Molecular Therapeutics had 13 more articles in the media than Kailera Therapeutics. MarketBeat recorded 17 mentions for 4D Molecular Therapeutics and 4 mentions for Kailera Therapeutics. 4D Molecular Therapeutics' average media sentiment score of 0.53 beat Kailera Therapeutics' score of -0.05 indicating that 4D Molecular Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
4D Molecular Therapeutics
7 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Kailera Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

4D Molecular Therapeutics presently has a consensus target price of $29.63, suggesting a potential upside of 87.14%. Kailera Therapeutics has a consensus target price of $42.75, suggesting a potential upside of 148.98%. Given Kailera Therapeutics' higher probable upside, analysts plainly believe Kailera Therapeutics is more favorable than 4D Molecular Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
4D Molecular Therapeutics
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80
Kailera Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.75

Summary

4D Molecular Therapeutics beats Kailera Therapeutics on 9 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding FDMT and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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FDMT vs. The Competition

Metric4D Molecular TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$874.51M$4.01B$7.37B$12.85B
Dividend YieldN/A3.64%2.53%11.08%
P/E Ratio-6.0211.62272.8824.24
Price / Sales10.261,338.17618.9699.81
Price / CashN/A105.1478.6253.99
Price / Book2.1416.8013.056.20
Net Income-$140.11M-$12.50M$3.47B$348.59M
7 Day Performance29.86%3.29%2.09%0.08%
1 Month Performance52.50%8.23%6.64%3.88%
1 Year Performance123.27%55.05%25.02%16.98%

4D Molecular Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
FDMT
4D Molecular Therapeutics
3.0677 of 5 stars
$15.83
-1.7%
$29.63
+87.1%
+123.3%$874.51M$85.21MN/A120
VRDN
Viridian Therapeutics
2.7292 of 5 stars
$23.09
+4.6%
$38.93
+68.6%
+26.3%$2.50B$70.85MN/A50
BCRX
BioCryst Pharmaceuticals
2.8354 of 5 stars
$9.94
+2.1%
$20.60
+107.2%
+11.7%$2.49B$874.84MN/A530
NKTR
Nektar Therapeutics
2.9193 of 5 stars
$72.67
-0.5%
$150.00
+106.4%
+173.8%$2.47B$55.23MN/A220
AMLX
Amylyx Pharmaceuticals
1.7939 of 5 stars
$21.43
-0.9%
$26.13
+21.9%
+315.7%$2.41B$87.37MN/A200

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This page (NASDAQ:FDMT) was last updated on 8/23/2026 by MarketBeat.com Staff.
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