HTG Molecular Diagnostics, Inc. (NASDAQ: HTGMQ) develops and commercializes molecular profiling solutions for clinical research and precision medicine applications. The company’s primary focus is on delivering sample-to-answer assays that streamline gene expression profiling, enabling high-throughput analysis of RNA and protein biomarkers. By leveraging its proprietary HTG EdgeSeq platform, HTG aims to simplify complex workflows and reduce hands-on time compared to traditional next-generation sequencing (NGS) methods.
The HTG EdgeSeq technology integrates microfluidic processing with NGS, allowing for direct interrogation of formalin-fixed, paraffin-embedded (FFPE) tissue and protein lysates without requiring separate RNA extraction or library preparation steps. Key products include the EdgeSeq Oncology Biomarker Panel, designed to profile hundreds of cancer-related genes, and the EdgeSeq Immuno-Oncology Assay, which targets immune-related gene signatures. These assays support biomarker discovery, translational research and companion diagnostic development in oncology, immunology and other therapeutic areas.
Headquartered in Tucson, Arizona, HTG serves a global customer base encompassing pharmaceutical and biotechnology companies, academic research centers, and clinical reference laboratories. The company’s offerings are utilized in preclinical studies and clinical trials to facilitate drug candidate selection, patient stratification and evaluation of treatment response. HTG’s commercial strategy combines direct sales in North America with distribution partnerships in Europe, Asia and other international markets.
Since its founding, HTG Molecular Diagnostics has emphasized innovation in molecular diagnostic workflows to accelerate precision medicine. The company’s leadership prioritizes comprehensive assay performance, operational efficiency and collaboration with research and clinical partners. Through its EdgeSeq platform and assay portfolio, HTG continues to advance tools that empower scientists and clinicians to uncover critical insights into disease biology and support the development of targeted therapeutic approaches.
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