Iterum Therapeutics (ITRM) Institutional Ownership $0.68 +0.05 (+7.31%) Closing price 09/5/2025 04:00 PM EasternExtended Trading$0.70 +0.02 (+3.66%) As of 09/5/2025 07:52 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Iterum Therapeutics (NASDAQ:ITRM)CurrentInstitutional OwnershipPercentage9.21%Number ofInstitutional Buyers(last 12 months)9TotalInstitutional Inflows(last 12 months)$1.22MNumber ofInstitutional Sellers(last 12 months)1TotalInstitutional Outflows(last 12 months)$176.41K Get ITRM Insider Trade Alerts Want to know when executives and insiders are buying or selling Iterum Therapeutics stock? 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Skip Chart & View Institutional Buying and Selling Data ITRM Institutional Buying and Selling by Quarter Iterum Therapeutics Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails8/14/2025 Jane Street Group LLC92,943$92K0.0%N/A0.208% 4/29/2025 OneDigital Investment Advisors LLC101,000$124K0.0%N/A0.292% 2/18/2025 Alpine Global Management LLC15,000$27K0.0%-76.9%0.055% 2/17/2025 Two Sigma Investments LP25,245$45K0.0%N/A0.092% 2/17/2025 Citadel Advisors LLC21,207$38K0.0%N/A0.077% 2/14/2025 Alpine Global Management LLC15,000$27K0.0%-76.9%0.055% 2/13/2025 Renaissance Technologies LLC438,816$777K0.0%N/A1.595% 1/31/2025Sanctuary Advisors LLC20,000$35K0.0%N/A0.073% 1/30/2025 Lee Financial Co16,000$28K0.0%N/A0.058% 1/28/2025 Apollon Financial LLC250,250$443K0.1%+11.3%0.909% Get the Latest News and Ratings for ITRM and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Iterum Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 11/15/2024 XTX Topco Ltd33,040$36K0.0%N/A0.146% 8/9/2024 Renaissance Technologies LLC64,022$73K0.0%-42.0%0.387% 8/4/2023 Apollon Wealth Management LLC200,000$214K0.0%N/A1.542% 11/10/2022 New Leaf Venture Partners L.L.C.97,084$157K0.1%-93.3%0.794% 10/6/2022 Krilogy Financial LLC20,000$32K0.0%-90.0%0.163% 7/14/2022 Krilogy Financial LLC200,000$40K0.0%N/A0.109% 11/16/2021 Squarepoint Ops LLC52,503$29K0.0%+106.9%0.029% 11/15/2021 Franklin Resources Inc.384,200$215K0.0%N/A0.210% 11/12/2021 Renaissance Technologies LLC644,567$360K0.0%-80.4%0.353% 10/25/2021 Krilogy Financial LLC81,000$45K0.0%+161.3%0.044% 9/17/2021 Virtu Financial LLC83,658$193K0.0%-37.2%0.046% 8/17/2021 Millennium Management LLC2,560,381$5.91M0.0%+3,304.5%1.429% 8/16/2021 Squarepoint Ops LLC25,382$59K0.0%-49.4%0.014% 8/16/2021 Cubist Systematic Strategies LLC89,431$207K0.0%N/A0.050% 8/13/2021 Renaissance Technologies LLC3,289,300$7.60M0.0%N/A1.836% 8/13/2021 Sigma Planning Corp17,153$40K0.0%N/A0.010% 8/13/2021QS Investors LLC384,200$888K0.0%N/A0.214% 8/12/2021 Insight Advisors LLC PA35,000$28K0.0%-88.5%0.020% 8/11/2021 Susquehanna Fundamental Investments LLC66,230$153K0.0%N/A0.037% 8/10/2021 National Asset Management Inc.32,100$75K0.0%-61.0%0.018% 5/17/2021 Royal Bank of Canada19,000$27K0.0%N/A0.011% (Data available from 1/1/2016 forward) ITRM Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of ITRM shares? During the previous two years, 10 institutional investors and hedge funds held shares of Iterum Therapeutics. The most heavily invested institutionals were Renaissance Technologies LLC ($777K), Apollon Financial LLC ($443K), OneDigital Investment Advisors LLC ($124K), Jane Street Group LLC ($92K), Two Sigma Investments LP ($45K), Citadel Advisors LLC ($38K), and XTX Topco Ltd ($36K).Learn more on Iterum Therapeutics' institutional investors. What percentage of Iterum Therapeutics' stock is owned by institutional investors? 9.21% of Iterum Therapeutics' stock is owned by institutional investors. Learn more on ITRM's institutional investor holdings. Which institutional investors have been buying Iterum Therapeutics' stock? Of the 9 institutional investors that purchased Iterum Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Renaissance Technologies LLC ($438.82K), OneDigital Investment Advisors LLC ($101K), Jane Street Group LLC ($92.94K), XTX Topco Ltd ($33.04K), Apollon Financial LLC ($25.50K), Two Sigma Investments LP ($25.25K), and Citadel Advisors LLC ($21.21K). How much institutional buying is happening at Iterum Therapeutics? Institutional investors have bought a total of 773,751 shares in the last 24 months. This purchase volume represents approximately $1.22M in transactions. Which of Iterum Therapeutics' major shareholders have been selling company stock? The following institutional investors have sold Iterum Therapeutics stock in the last 24 months: Alpine Global Management LLC ($99.67K). How much institutional selling is happening at Iterum Therapeutics? Institutional investors have sold a total of 99,666 shares in the last 24 months. This volume of shares sold represents approximately $176.41K in transactions. Related Companies Protara Therapeutics Major Shareholders Fate Therapeutics Major Shareholders Invivyd Major Shareholders Spero Therapeutics Major Shareholders Biomea Fusion Major Shareholders Corbus Pharmaceuticals Major Shareholders Connect Biopharma Major Shareholders MacroGenics Major Shareholders Cassava Sciences Major Shareholders Coya Therapeutics Major Shareholders This page (NASDAQ:ITRM) was last updated on 9/6/2025 by MarketBeat.com Staff From Our PartnersWarren Buffett's Strangest AI InvestmentTrump Schedules Controversial 'Market Reset' for September 30 Behind closed doors, the White House has orde...Altimetry | SponsoredMusk Warns. Trump Acts. 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