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Spero Therapeutics (SPRO) Institutional Ownership

Spero Therapeutics logo
$2.81 -0.03 (-1.06%)
Closing price 07/11/2025 04:00 PM Eastern
Extended Trading
$2.84 +0.03 (+1.07%)
As of 07/11/2025 07:47 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.
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Institutional Ownership Changes (13F Filings) for Spero Therapeutics (NASDAQ:SPRO)

Current
Institutional Ownership
Percentage
25.60%
Number of
Institutional Buyers
(last 12 months)
14
Total
Institutional Inflows
(last 12 months)
$4.51M
Number of
Institutional Sellers
(last 12 months)
5
Total
Institutional Outflows
(last 12 months)
$386.02K
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SPRO Institutional Buying and Selling by Quarter

Spero Therapeutics Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
7/7/2025 Capital Asset Advisory Services LLC32,548$94K0.0%N/A0.058%
5/28/2025Anson Funds Management LP3,798,932$2.74M0.4%-1.1%6.795%
5/21/2025Acadian Asset Management LLC871,212$626K0.0%-16.2%1.558%
5/14/2025Anson Funds Management LP7,638,818$5.50M0.8%+98.9%13.662%
5/7/2025Mackenzie Financial Corp209,031$151K0.0%+11.4%0.374%
2/20/2025Mackenzie Financial Corp187,559$193K0.0%+487.9%0.344%
2/17/2025Squarepoint Ops LLC55,051$57K0.0%N/A0.101%
2/17/2025Anson Funds Management LP3,839,886$3.96M0.4%+2.4%7.043%
2/14/2025Jane Street Group LLC52,869$54K0.0%N/A0.097%
2/14/2025Northern Trust Corp86,447$89K0.0%-22.5%0.159%
2/14/2025 Three Seasons Wealth LLC30,000$31K0.0%N/A0.055%
2/13/2025XTX Topco Ltd30,138$31K0.0%N/A0.055%
2/13/2025Renaissance Technologies LLC1,105,591$1.14M0.0%+13.4%2.028%
2/13/2025ADAR1 Capital Management LLC801,277$825K0.2%+7.8%1.470%
2/12/2025JPMorgan Chase & Co.61,624$63K0.0%+26,011.9%0.113%
2/11/2025Prudential Financial Inc.49,200$51K0.0%N/A0.090%
2/11/2025Virtu Financial LLC46,046$47K0.0%N/A0.084%
2/10/2025Monimus Capital Management LP310,908$320K0.3%N/A0.570%
2/6/2025Atlas Venture Life Science Advisors LLC305,255$314K0.0%-24.2%0.560%
11/16/2024Geode Capital Management LLC481,187$645K0.0%-2.2%0.891%
8/9/2024Renaissance Technologies LLC975,952$1.27M0.0%+14.2%1.808%
8/9/2024Atlas Venture Life Science Advisors LLC535,336$696K0.1%-11.9%0.992%
8/6/2024Acadian Asset Management LLC1,071,860$1.39M0.0%+40.6%1.985%
5/20/2024Virtu Financial LLC18,180$31K0.0%N/A0.034%
5/16/2024Murchinson Ltd.873,910$1.50M0.1%+1.3%1.622%
5/14/2024Anson Funds Management LP3,750,450$6.45M0.4%-12.7%6.959%
5/10/2024Acadian Asset Management LLC762,598$1.31M0.0%+121.8%1.415%
5/10/2024Vanguard Group Inc.1,653,432$2.84M0.0%+0.6%3.068%
5/6/2024Atlas Venture Life Science Advisors LLC607,613$1.05M0.1%-40.0%1.128%
2/14/2024ADAR1 Capital Management LLC1,067,711$1.57M0.6%N/A2.015%
11/15/2023Rock Springs Capital Management LP57,373$69K0.0%-91.4%0.109%
11/14/2023AWM Investment Company Inc.333,400$403K0.1%-13.0%0.632%
11/13/2023Acadian Asset Management LLC272,024$327K0.0%+56.8%0.516%
8/14/2023Anson Funds Management LP3,444,862$5.00M0.8%+3.0%6.537%
8/11/2023AWM Investment Company Inc.383,400$556K0.1%-70.5%0.729%
8/11/2023Atlas Venture Life Science Advisors LLC1,013,438$1.47M0.2%-1.7%1.928%
8/7/2023Acadian Asset Management LLC173,539$250K0.0%N/A0.330%
8/7/2023Royce & Associates LP22,851$33K0.0%N/A0.043%
8/3/2023Mackenzie Financial Corp17,198$25K0.0%N/A0.033%
7/27/2023Virtu Financial LLC22,195$32K0.0%N/A0.042%
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5/15/2023Anson Funds Management LP3,344,862$4.85M0.8%+10.8%6.363%
4/17/2023Bourgeon Capital Management LLC25,600$37K0.0%+95.4%0.049%
2/14/2023AWM Investment Company Inc.1,300,400$2.25M0.3%-43.5%3.708%
11/16/2022Alphabet Inc.889,979$1.78M0.1%N/A2.538%
11/16/2022Anson Funds Management LP1,473,872$2.95M0.3%N/A4.203%
11/15/2022Murchinson Ltd.762,700$1.53M0.4%N/A2.175%
11/15/2022BVF Inc. IL1,929,376$3.86M0.2%-37.6%5.501%
10/21/2022Weitzel Financial Services Inc.14,200$28K0.0%N/A0.040%
8/9/2022Kingsbury Capital Investment Advisors LLC60,844$45K0.1%N/A0.185%
7/27/2022Assenagon Asset Management S.A.131,020$97K0.0%+466.6%0.399%
5/17/2022Rock Springs Capital Management LP990,913$8.62M0.2%+4.8%3.025%
5/16/2022Eversept Partners LP59,639$519K0.0%N/A0.182%
5/16/2022Granahan Investment Management LLC113,322$986K0.0%-70.1%0.346%
5/11/2022GSA Capital Partners LLP25,916$225K0.0%N/A0.079%
5/6/2022Sentinel Pension Advisors Inc.42,000$365K0.1%+39.1%0.128%
5/5/2022New York State Common Retirement Fund17,123$149K0.0%-68.1%0.052%
5/3/2022Bourgeon Capital Management LLC63,096$549K0.1%+23.1%0.193%
4/25/2022Assenagon Asset Management S.A.23,123$201K0.0%N/A0.071%
2/14/2022Williams Jones Wealth Management LLC.75,000$1.20M0.0%-28.9%0.232%
2/10/2022Rafferty Asset Management LLC34,958$560K0.0%+86.1%0.108%
2/9/2022BNP Paribas Arbitrage SA8,997$144K0.0%+107.2%0.028%
2/9/2022Dimensional Fund Advisors LP371,222$5.94M0.0%+12.6%1.148%
2/8/2022Sentinel Pension Advisors Inc.30,200$484K0.2%+49.5%0.093%
2/8/2022Northern Trust Corp253,200$4.05M0.0%-1.8%0.783%
2/4/2022IndexIQ Advisors LLC28,689$459K0.0%-6.1%0.089%
2/3/2022OUP Management Co. LLC249,070$3.99M1.8%N/A0.771%
2/2/2022New York State Common Retirement Fund53,728$860K0.0%-24.6%0.166%
1/31/2022Bourgeon Capital Management LLC51,246$820K0.2%+22.8%0.159%
1/28/2022Allspring Global Investments Holdings LLC10,186$163K0.0%N/A0.032%
1/21/2022Russell Investments Group Ltd.7,250$116K0.0%-11.0%0.022%
1/10/2022Patriot Financial Group Insurance Agency LLC4,150$66K0.0%N/A0.013%
11/16/2021BVF Inc. IL1,809,352$33.31M1.3%-15.4%5.628%
11/15/2021Rock Springs Capital Management LP941,543$17.33M0.4%-2.5%2.929%
11/15/2021Royal Bank of Canada180,102$3.32M0.0%+8,249.7%0.560%
11/15/2021Granahan Investment Management Inc. MA555,614$10.23M0.2%+67.0%1.728%
11/15/2021Dimensional Fund Advisors LP329,633$6.07M0.0%-12.0%1.025%
11/12/2021Brandywine Global Investment Management LLC58,400$1.08M0.0%N/A0.182%
11/12/2021The Manufacturers Life Insurance Company14,276$263K0.0%-10.4%0.044%
11/12/2021Geode Capital Management LLC444,914$8.19M0.0%+7.5%1.384%
11/10/2021Goldman Sachs Group Inc.137,579$2.53M0.0%+1.0%0.428%
11/10/2021IndexIQ Advisors LLC30,543$562K0.0%+11.1%0.095%
11/10/2021Citigroup Inc.16,085$296K0.0%-59.1%0.050%
11/10/2021Rafferty Asset Management LLC18,789$346K0.0%-21.4%0.058%
11/10/2021Alliancebernstein L.P.11,934$220K0.0%-16.2%0.037%
11/9/2021Bourgeon Capital Management LLC41,746$769K0.2%N/A0.130%
11/9/2021Barclays PLC9,965$183K0.0%+79.1%0.031%
11/9/2021BlackRock Inc.1,802,528$33.19M0.0%+1.3%5.607%
11/8/2021Russell Investments Group Ltd.8,147$149K0.0%-53.1%0.025%
11/5/2021Advisor Group Holdings Inc.2,548$46K0.0%-74.7%0.008%
11/2/2021New York State Common Retirement Fund71,220$1.31M0.0%+42.8%0.222%
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11/1/2021SG Americas Securities LLC10,617$195K0.0%N/A0.033%
10/29/2021Janney Montgomery Scott LLC26,000$479K0.0%+10.6%0.081%
10/20/2021Sentinel Pension Advisors Inc.20,200$372K0.1%N/A0.063%
9/3/2021Parametric Portfolio Associates LLC29,947$418K0.0%-4.7%0.093%
8/17/2021Metropolitan Life Insurance Co NY6,987$98K0.0%+139,640.0%0.022%
8/17/2021MetLife Investment Management LLC9,977$139K0.0%+392.0%0.031%
8/16/2021California State Teachers Retirement System33,446$467K0.0%+8.2%0.104%
8/16/2021Charles Schwab Investment Management Inc.60,496$845K0.0%+13.4%0.188%
8/16/2021State Street Corp810,738$11.32M0.0%-40.2%2.522%
8/16/2021Goldman Sachs Group Inc.136,262$1.90M0.0%-46.7%0.424%
(Data available from 1/1/2016 forward)

SPRO Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of SPRO shares?

During the previous two years, 22 institutional investors and hedge funds held shares of Spero Therapeutics. The most heavily invested institutionals were Vanguard Group Inc. ($2.84M), Anson Funds Management LP ($2.74M), Murchinson Ltd. ($1.50M), Renaissance Technologies LLC ($1.14M), ADAR1 Capital Management LLC ($825K), Geode Capital Management LLC ($645K), and Acadian Asset Management LLC ($626K).Learn more on Spero Therapeutics' institutional investors.

What percentage of Spero Therapeutics' stock is owned by institutional investors?

25.60% of Spero Therapeutics' stock is owned by institutional investors. Learn more on SPRO's institutional investor holdings.

Which institutional investors have been buying Spero Therapeutics' stock?

Of the 17 institutional investors that purchased Spero Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Anson Funds Management LP ($3.99M), ADAR1 Capital Management LLC ($1.13M), Acadian Asset Management LLC ($1.00M), Monimus Capital Management LP ($310.91K), Renaissance Technologies LLC ($252.43K), Mackenzie Financial Corp ($194.33K), and Virtu Financial LLC ($86.42K).

How much institutional buying is happening at Spero Therapeutics?

Institutional investors have bought a total of 5,353,154 shares in the last 24 months. This purchase volume represents approximately $4.51M in transactions.

Which of Spero Therapeutics' major shareholders have been selling company stock?

The following institutional investors have sold Spero Therapeutics stock in the last 24 months: Atlas Venture Life Science Advisors LLC ($169.91K), Acadian Asset Management LLC ($168.71K), Anson Funds Management LP ($40.95K), Northern Trust Corp ($25.05K), and Geode Capital Management LLC ($11K).

How much institutional selling is happening at Spero Therapeutics?

Institutional investors have sold a total of 415,621 shares in the last 24 months. This volume of shares sold represents approximately $386.02K in transactions.


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This page (NASDAQ:SPRO) was last updated on 7/12/2025 by MarketBeat.com Staff
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