Taysha Gene Therapies (TSHA) Institutional Ownership

$5.10 -0.25 (-4.59%)

As of 11:49 AM Eastern

Current Institutional Ownership Percentage: 77.70%
Number of Institutional Buyers (last 12 months): 106
Total Institutional Inflows (last 12 months): $298.85M

Number of Institutional Sellers (last 12 months): 33
Total Institutional Outflows (last 12 months): $149.54M

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TSHA Institutional Buying and Selling by Quarter

Taysha Gene Therapies Major Shareholders & Ownership History

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Reporting Date	Major Shareholder Name	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
9/9/2026	Engineers Gate Manager LP	104,132	$709K	0.0%	N/A	0.032%
9/9/2026	Squarepoint Ops LLC	569,269	$3.88M	0.0%	+38.8%	0.175%
9/8/2026	Arizona State Retirement System	39,633	$270K	0.0%	+5.4%	0.012%
8/24/2026	California State Teachers Retirement System	1,153,437	$7.86M	0.0%	+742.3%	0.354%
8/22/2026	Seven Fleet Capital Management LP	1,504,400	$9.94M	1.6%	+140.4%	0.462%
8/19/2026	Wellington Management Group LLP	3,975,605	$27.07M	0.0%	+534.7%	1.220%
8/6/2026	Bank of New York Mellon Corp	697,971	$4.75M	0.0%	N/A	0.243%
7/9/2026	Hennion & Walsh Asset Management Inc.	519,120	$3.54M	0.1%	+32.6%	0.181%
6/12/2026	Militia Capital Management LLC	46,500	$208K	0.0%	N/A	0.016%
6/4/2026	Seven Fleet Capital Management LP	625,708	$2.80M	0.9%	+274.2%	0.218%
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5/19/2026	Bank of America Corp DE	1,677,046	$7.50M	0.0%	+45.5%	0.584%
5/18/2026	ADAR1 Capital Management LLC	2,979,429	$13.32M	0.8%	+19.4%	1.037%
5/16/2026	The Manufacturers Life Insurance Company	99,371	$444K	0.0%	+48.1%	0.035%
5/15/2026	Rice Hall James & Associates LLC	1,944,671	$8.69M	0.5%	+53.0%	0.677%
5/15/2026	Granahan Investment Management LLC	883,241	$3.95M	0.2%	+25.5%	0.307%
5/15/2026	Affinity Asset Advisors LLC	1,000,000	$4.47M	0.2%	-69.7%	0.348%
5/14/2026	Healthcare of Ontario Pension Plan Trust Fund	2,883,301	$12.89M	0.0%	-22.5%	1.003%
5/14/2026	Renaissance Technologies LLC	413,203	$1.85M	0.0%	+141.5%	0.144%
5/14/2026	Siren L.L.C.	8,829,913	$39.47M	1.1%	-12.8%	3.073%
5/14/2026	Sei Investments Co.	51,472	$230K	0.0%	+7.6%	0.018%
5/13/2026	Cetera Investment Advisers	28,450	$127K	0.0%	+34.5%	0.010%
5/13/2026	Militia Capital Management LLC	46,500	$208K	0.0%	N/A	0.016%
5/5/2026	Bank of New York Mellon Corp	608,123	$2.72M	0.0%	-2.6%	0.212%
5/4/2026	Principal Financial Group Inc.	16,185	$72K	0.0%	+26.2%	0.006%
5/4/2026	Chicago Partners Investment Group LLC	170,751	$763K	0.0%	+2.5%	0.059%
4/29/2026	R Squared Ltd	11,276	$50K	0.0%	N/A	0.004%
4/27/2026	Y Intercept Hong Kong Ltd	11,486	$51K	0.0%	N/A	0.004%
4/16/2026	SG Americas Securities LLC	2,176,742	$9.73M	0.0%	+178.5%	0.758%
4/16/2026	Allegheny Financial Group	12,000	$54K	0.0%	-54.5%	0.004%
3/3/2026	Caitong International Asset Management Co. Ltd	25,577	$141K	0.0%	+698.3%	0.009%
2/26/2026	Seven Fleet Capital Management LP	167,223	$920K	0.7%	N/A	0.061%
2/19/2026	Invesco Ltd.	1,332,780	$7.33M	0.0%	+376.3%	0.487%
2/18/2026	Oracle Investment Management Inc.	265,000	$1.46M	0.9%	N/A	0.097%
2/18/2026	ADAR1 Capital Management LLC	2,495,809	$13.73M	1.0%	-12.0%	0.911%
2/18/2026	Voloridge Investment Management LLC	54,785	$301K	0.0%	N/A	0.020%
2/18/2026	Vestal Point Capital LP	13,750,000	$75.63M	2.6%	+150.0%	5.020%
2/18/2026	Virtus Investment Advisers LLC	45,946	$253K	0.1%	+7.0%	0.017%
2/18/2026	Wellington Management Group LLP	711,235	$3.91M	0.0%	+25.2%	0.260%
2/18/2026	SummitTX Capital L.P.	56,595	$311K	0.0%	N/A	0.021%
2/18/2026	Sphera Funds Management LTD.	368,146	$2.03M	0.4%	-9.8%	0.134%
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2/18/2026	Superstring Capital Management LP	980,768	$5.39M	2.9%	N/A	0.358%
2/18/2026	RTW Investments LP	16,398,297	$90.19M	0.9%	-32.7%	5.987%
2/18/2026	Millennium Management LLC	3,178,863	$17.48M	0.0%	-24.2%	1.161%
2/18/2026	Janus Henderson Group PLC	69,000	$378K	0.0%	N/A	0.025%
2/18/2026	First Manhattan CO. LLC.	43,500	$239K	0.0%	+52.6%	0.016%
2/18/2026	Casdin Capital LLC	1,500,000	$8.25M	0.5%	N/A	0.548%
2/18/2026	Balyasny Asset Management L.P.	42,070	$231K	0.0%	N/A	0.015%
2/18/2026	Boothbay Fund Management LLC	309,481	$1.70M	0.0%	-25.5%	0.113%
2/17/2026	Guggenheim Capital LLC	11,111	$61K	0.0%	N/A	0.004%
2/17/2026	ADAR1 Capital Management LLC	2,495,809	$13.73M	1.0%	-12.0%	0.911%
2/17/2026	J. Goldman & Co LP	33,750	$186K	0.0%	N/A	0.012%
2/17/2026	AQR Capital Management LLC	168,862	$929K	0.0%	+11.8%	0.062%
2/17/2026	Cetera Investment Advisers	21,154	$116K	0.0%	+30.9%	0.008%
2/17/2026	Price T Rowe Associates Inc. MD	121,814	$670K	0.0%	+7.0%	0.044%
2/17/2026	Adage Capital Partners GP L.L.C.	1,328,000	$7.30M	0.0%	-60.1%	0.485%
2/17/2026	California State Teachers Retirement System	138,580	$762K	0.0%	+1,236.0%	0.051%
2/17/2026	Granahan Investment Management LLC	703,971	$3.87M	0.2%	-37.0%	0.257%
2/17/2026	State of Wisconsin Investment Board	113,178	$622K	0.0%	+163.5%	0.041%
2/17/2026	Captrust Financial Advisors	15,113	$83K	0.0%	N/A	0.006%
2/17/2026	Royal Bank of Canada	6,302	$34K	0.0%	-98.9%	0.002%
2/17/2026	Mangrove Partners IM LLC	20,546	$113K	0.0%	N/A	0.008%
2/17/2026	Militia Capital Partners LP	46,500	$256K	0.1%	-30.4%	0.017%
2/17/2026	Polar Capital Holdings Plc	7,931,403	$43.62M	0.2%	+49.8%	2.896%
2/17/2026	Rice Hall James & Associates LLC	1,270,645	$6.99M	0.4%	+119.8%	0.464%
2/16/2026	Squarepoint Ops LLC	471,577	$2.59M	0.0%	+137.7%	0.172%
2/16/2026	Panagora Asset Management Inc.	11,574	$64K	0.0%	N/A	0.004%
2/16/2026	Focus Partners Wealth	295,516	$1.63M	0.0%	N/A	0.108%
2/16/2026	Healthcare of Ontario Pension Plan Trust Fund	3,722,000	$20.47M	0.0%	N/A	1.359%
2/16/2026	Barclays PLC	5,539,001	$30.47M	0.0%	+7.6%	2.022%
2/13/2026	The Manufacturers Life Insurance Company	67,085	$369K	0.0%	-4.0%	0.024%
2/13/2026	Affinity Asset Advisors LLC	3,300,000	$18.15M	1.0%	+10.0%	1.205%
2/13/2026	Morgan Stanley	18,078,518	$99.43M	0.0%	-6.4%	6.600%
2/13/2026	Rafferty Asset Management LLC	344,784	$1.90M	0.0%	+43.8%	0.126%
2/13/2026	Siren L.L.C.	10,129,913	$55.72M	1.7%	-8.0%	3.698%
2/13/2026	Charles Schwab Investment Management Inc.	1,902,978	$10.47M	0.0%	+3.1%	0.695%
2/13/2026	State Street Corp	10,790,084	$59.35M	0.0%	+49.1%	3.939%
2/13/2026	Caitong International Asset Management Co. Ltd	7,811	$43K	0.1%	+143.8%	0.003%
2/13/2026	UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	167,500	$921K	0.0%	N/A	0.061%
2/13/2026	Wells Fargo & Company MN	305,086	$1.68M	0.0%	+110.3%	0.111%
2/12/2026	HRT Financial LP	409,254	$2.25M	0.0%	N/A	0.149%
2/12/2026	MetLife Investment Management LLC	113,266	$623K	0.0%	-10.8%	0.041%
2/12/2026	Cibc World Markets Corp	14,612	$80K	0.0%	N/A	0.005%
2/12/2026	Commonwealth Equity Services LLC	55,657	$306K	0.0%	-4.5%	0.020%
2/12/2026	Renaissance Technologies LLC	171,100	$941K	0.0%	N/A	0.062%
2/12/2026	Dimensional Fund Advisors LP	490,472	$2.70M	0.0%	+42.1%	0.179%
2/12/2026	Ensign Peak Advisors Inc	275,111	$1.51M	0.0%	N/A	0.100%
2/12/2026	Informed Momentum Co LLC	823,758	$4.53M	0.5%	N/A	0.301%
2/12/2026	Alps Advisors Inc.	224,920	$1.24M	0.0%	N/A	0.082%
2/12/2026	Swiss National Bank	268,800	$1.48M	0.0%	N/A	0.098%
2/12/2026	Polen Capital Management LLC	156,586	$861K	0.0%	N/A	0.057%
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2/12/2026	Nuveen LLC	545,286	$3.00M	0.0%	+7.5%	0.199%
2/11/2026	Deutsche Bank AG	160,779	$884K	0.0%	+30.9%	0.059%
2/11/2026	JPMorgan Chase & Co.	774,412	$4.26M	0.0%	+161.4%	0.283%
2/11/2026	Los Angeles Capital Management LLC	32,918	$181K	0.0%	N/A	0.012%
2/10/2026	CIBC Asset Management Inc	11,959	$66K	0.0%	N/A	0.004%
2/10/2026	Goldman Sachs Group Inc.	13,692,739	$75.31M	0.0%	+2.3%	4.999%
2/10/2026	AXQ Capital LP	37,804	$208K	0.0%	-23.9%	0.014%
2/10/2026	Norges Bank	1,837,800	$10.11M	0.0%	N/A	0.671%
2/10/2026	Intech Investment Management LLC	71,069	$391K	0.0%	+3.6%	0.026%
2/9/2026	Geode Capital Management LLC	5,387,026	$29.63M	0.0%	+4.1%	1.967%

TSHA Institutional Ownership - Frequently Asked Questions

During the previous two years, 160 institutional investors and hedge funds held shares of Taysha Gene Therapies. The most heavily invested institutionals were Morgan Stanley ($99.43M), RTW Investments LP ($90.19M), Vestal Point Capital LP ($75.63M), Goldman Sachs Group Inc. ($75.31M), Vanguard Group Inc. ($72.97M), State Street Corp ($59.35M), and Polar Capital Holdings Plc ($43.62M).Learn more on Taysha Gene Therapies' institutional investors.

77.70% of Taysha Gene Therapies' stock is owned by institutional investors. Learn more on TSHA's institutional investor holdings.

Of the 149 institutional investors that purchased Taysha Gene Therapies' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Vestal Point Capital LP ($10.75M), Jefferies Financial Group Inc. ($10.31M), Adage Capital Partners GP L.L.C. ($9.84M), Octagon Capital Advisors LP ($8.02M), Barclays PLC ($5.56M), Wellington Management Group LLP ($4.24M), and Healthcare of Ontario Pension Plan Trust Fund ($3.72M).

Institutional investors have bought a total of 59,844,427 shares in the last 24 months. This purchase volume represents approximately $298.85M in transactions.

Of the 33 institutional investors that sold Taysha Gene Therapies' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Jefferies Financial Group Inc. ($10.29M), RTW Investments LP ($7.96M), Affinity Asset Advisors LLC ($2.30M), Siren L.L.C. ($2.18M), Adage Capital Partners GP L.L.C. ($2M), Morgan Stanley ($1.23M), and Millennium Management LLC ($1.01M).

Institutional investors have sold a total of 32,062,956 shares in the last 24 months. This volume of shares sold represents approximately $149.54M in transactions.

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Institutional ownership data for NASDAQ:TSHA is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 9/9/2026. New 13F filings are added each quarter as they're published.

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Taysha Gene Therapies (TSHA) Institutional Ownership

TSHA Institutional Buying and Selling by Quarter

Taysha Gene Therapies Major Shareholders & Ownership History

TSHA Institutional Ownership - Frequently Asked Questions

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Taysha Gene Therapies (TSHA) Institutional Ownership

Institutional Ownership Changes (13F Filings) for Taysha Gene Therapies (NASDAQ:TSHA)

TSHA Institutional Buying and Selling by Quarter

Taysha Gene Therapies Major Shareholders & Ownership History

TSHA Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of TSHA shares?

What percentage of Taysha Gene Therapies' stock is owned by institutional investors?

Which institutional investors have been buying Taysha Gene Therapies' stock?

How much institutional buying is happening at Taysha Gene Therapies?

Which of Taysha Gene Therapies' major shareholders have been selling company stock?

How much institutional selling is happening at Taysha Gene Therapies?

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