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Taysha Gene Therapies (TSHA) Competitors

Taysha Gene Therapies logo
$6.34 +0.13 (+2.09%)
Closing price 06/26/2026 04:00 PM Eastern
Extended Trading
$6.28 -0.06 (-0.95%)
As of 06/26/2026 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

TSHA vs. HHH, PTGX, IMVT, RYTM, and LNTH

Should you buy Taysha Gene Therapies stock or one of its competitors? MarketBeat compares Taysha Gene Therapies with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Taysha Gene Therapies include Howard Hughes (HHH), Protagonist Therapeutics (PTGX), Immunovant (IMVT), Rhythm Pharmaceuticals (RYTM), and Lantheus (LNTH).

How does Taysha Gene Therapies compare to Howard Hughes?

Howard Hughes (NYSE:HHH) and Taysha Gene Therapies (NASDAQ:TSHA) are related companies, but which is the better investment? We will compare the two businesses based on the strength of their risk, dividends, valuation, media sentiment, analyst recommendations, institutional ownership, profitability and earnings.

Howard Hughes presently has a consensus price target of $85.00, suggesting a potential upside of 17.62%. Taysha Gene Therapies has a consensus price target of $12.38, suggesting a potential upside of 95.34%. Given Taysha Gene Therapies' stronger consensus rating and higher probable upside, analysts clearly believe Taysha Gene Therapies is more favorable than Howard Hughes.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Howard Hughes
1 Sell rating(s)
2 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.67
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
11 Buy rating(s)
2 Strong Buy rating(s)
3.00

Howard Hughes has a net margin of 8.04% compared to Taysha Gene Therapies' net margin of 0.00%. Howard Hughes' return on equity of 5.41% beat Taysha Gene Therapies' return on equity.

Company Net Margins Return on Equity Return on Assets
Howard Hughes8.04% 5.41% 1.61%
Taysha Gene Therapies N/A -56.07%-40.16%

Howard Hughes has higher revenue and earnings than Taysha Gene Therapies. Taysha Gene Therapies is trading at a lower price-to-earnings ratio than Howard Hughes, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Howard Hughes$1.47B2.92$131.88M$2.0435.42
Taysha Gene Therapies$9.77M186.48-$109M-$0.38N/A

93.8% of Howard Hughes shares are held by institutional investors. Comparatively, 77.7% of Taysha Gene Therapies shares are held by institutional investors. 48.0% of Howard Hughes shares are held by insiders. Comparatively, 3.8% of Taysha Gene Therapies shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Howard Hughes has a beta of 1.14, meaning that its stock price is 14% more volatile than the broader market. Comparatively, Taysha Gene Therapies has a beta of 1.19, meaning that its stock price is 19% more volatile than the broader market.

In the previous week, Taysha Gene Therapies had 13 more articles in the media than Howard Hughes. MarketBeat recorded 15 mentions for Taysha Gene Therapies and 2 mentions for Howard Hughes. Howard Hughes' average media sentiment score of 1.00 beat Taysha Gene Therapies' score of 0.44 indicating that Howard Hughes is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Howard Hughes
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Taysha Gene Therapies
3 Very Positive mention(s)
0 Positive mention(s)
9 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Howard Hughes beats Taysha Gene Therapies on 10 of the 17 factors compared between the two stocks.

How does Taysha Gene Therapies compare to Protagonist Therapeutics?

Taysha Gene Therapies (NASDAQ:TSHA) and Protagonist Therapeutics (NASDAQ:PTGX) are both medical companies, but which is the better stock? We will contrast the two companies based on the strength of their institutional ownership, media sentiment, earnings, dividends, profitability, analyst recommendations, valuation and risk.

Taysha Gene Therapies has a net margin of 0.00% compared to Protagonist Therapeutics' net margin of -154.88%. Protagonist Therapeutics' return on equity of -17.76% beat Taysha Gene Therapies' return on equity.

Company Net Margins Return on Equity Return on Assets
Taysha Gene TherapiesN/A -56.07% -40.16%
Protagonist Therapeutics -154.88%-17.76%-16.47%

77.7% of Taysha Gene Therapies shares are held by institutional investors. Comparatively, 98.6% of Protagonist Therapeutics shares are held by institutional investors. 3.8% of Taysha Gene Therapies shares are held by insiders. Comparatively, 5.2% of Protagonist Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Taysha Gene Therapies has higher earnings, but lower revenue than Protagonist Therapeutics. Protagonist Therapeutics is trading at a lower price-to-earnings ratio than Taysha Gene Therapies, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Taysha Gene Therapies$9.77M186.48-$109M-$0.38N/A
Protagonist Therapeutics$46.02M170.32-$130.15M-$1.81N/A

Taysha Gene Therapies has a beta of 1.19, meaning that its share price is 19% more volatile than the broader market. Comparatively, Protagonist Therapeutics has a beta of 1.85, meaning that its share price is 85% more volatile than the broader market.

Taysha Gene Therapies presently has a consensus target price of $12.38, indicating a potential upside of 95.34%. Protagonist Therapeutics has a consensus target price of $115.21, indicating a potential downside of 5.47%. Given Taysha Gene Therapies' stronger consensus rating and higher probable upside, analysts clearly believe Taysha Gene Therapies is more favorable than Protagonist Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
11 Buy rating(s)
2 Strong Buy rating(s)
3.00
Protagonist Therapeutics
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.88

In the previous week, Taysha Gene Therapies had 7 more articles in the media than Protagonist Therapeutics. MarketBeat recorded 15 mentions for Taysha Gene Therapies and 8 mentions for Protagonist Therapeutics. Taysha Gene Therapies' average media sentiment score of 0.44 beat Protagonist Therapeutics' score of 0.25 indicating that Taysha Gene Therapies is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Taysha Gene Therapies
3 Very Positive mention(s)
0 Positive mention(s)
9 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Protagonist Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Taysha Gene Therapies beats Protagonist Therapeutics on 10 of the 17 factors compared between the two stocks.

How does Taysha Gene Therapies compare to Immunovant?

Immunovant (NASDAQ:IMVT) and Taysha Gene Therapies (NASDAQ:TSHA) are both medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their profitability, institutional ownership, media sentiment, dividends, risk, analyst recommendations, earnings and valuation.

Immunovant currently has a consensus price target of $37.33, indicating a potential downside of 3.90%. Taysha Gene Therapies has a consensus price target of $12.38, indicating a potential upside of 95.34%. Given Taysha Gene Therapies' stronger consensus rating and higher possible upside, analysts clearly believe Taysha Gene Therapies is more favorable than Immunovant.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Immunovant
1 Sell rating(s)
4 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.45
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
11 Buy rating(s)
2 Strong Buy rating(s)
3.00

Immunovant has a beta of 0.76, indicating that its stock price is 24% less volatile than the broader market. Comparatively, Taysha Gene Therapies has a beta of 1.19, indicating that its stock price is 19% more volatile than the broader market.

47.1% of Immunovant shares are held by institutional investors. Comparatively, 77.7% of Taysha Gene Therapies shares are held by institutional investors. 1.8% of Immunovant shares are held by insiders. Comparatively, 3.8% of Taysha Gene Therapies shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

In the previous week, Taysha Gene Therapies had 2 more articles in the media than Immunovant. MarketBeat recorded 15 mentions for Taysha Gene Therapies and 13 mentions for Immunovant. Taysha Gene Therapies' average media sentiment score of 0.44 beat Immunovant's score of -0.75 indicating that Taysha Gene Therapies is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Immunovant
1 Very Positive mention(s)
4 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Negative
Taysha Gene Therapies
3 Very Positive mention(s)
0 Positive mention(s)
9 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Taysha Gene Therapies has higher revenue and earnings than Immunovant. Taysha Gene Therapies is trading at a lower price-to-earnings ratio than Immunovant, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ImmunovantN/AN/A-$505.61M-$2.78N/A
Taysha Gene Therapies$9.77M186.48-$109M-$0.38N/A

Taysha Gene Therapies' return on equity of -56.07% beat Immunovant's return on equity.

Company Net Margins Return on Equity Return on Assets
ImmunovantN/A -65.66% -59.88%
Taysha Gene Therapies N/A -56.07%-40.16%

Summary

Taysha Gene Therapies beats Immunovant on 14 of the 15 factors compared between the two stocks.

How does Taysha Gene Therapies compare to Rhythm Pharmaceuticals?

Taysha Gene Therapies (NASDAQ:TSHA) and Rhythm Pharmaceuticals (NASDAQ:RYTM) are both medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their media sentiment, valuation, earnings, profitability, dividends, risk, analyst recommendations and institutional ownership.

Taysha Gene Therapies has a net margin of 0.00% compared to Rhythm Pharmaceuticals' net margin of -93.33%. Taysha Gene Therapies' return on equity of -56.07% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Taysha Gene TherapiesN/A -56.07% -40.16%
Rhythm Pharmaceuticals -93.33%-203.25%-44.99%

Taysha Gene Therapies presently has a consensus target price of $12.38, indicating a potential upside of 95.34%. Rhythm Pharmaceuticals has a consensus target price of $133.13, indicating a potential upside of 21.20%. Given Taysha Gene Therapies' stronger consensus rating and higher probable upside, equities research analysts plainly believe Taysha Gene Therapies is more favorable than Rhythm Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
11 Buy rating(s)
2 Strong Buy rating(s)
3.00
Rhythm Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.83

77.7% of Taysha Gene Therapies shares are held by institutional investors. 3.8% of Taysha Gene Therapies shares are held by insiders. Comparatively, 5.9% of Rhythm Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Taysha Gene Therapies has higher earnings, but lower revenue than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Taysha Gene Therapies, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Taysha Gene Therapies$9.77M186.48-$109M-$0.38N/A
Rhythm Pharmaceuticals$189.76M39.67-$196.54M-$3.13N/A

In the previous week, Taysha Gene Therapies had 8 more articles in the media than Rhythm Pharmaceuticals. MarketBeat recorded 15 mentions for Taysha Gene Therapies and 7 mentions for Rhythm Pharmaceuticals. Rhythm Pharmaceuticals' average media sentiment score of 0.71 beat Taysha Gene Therapies' score of 0.44 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Taysha Gene Therapies
3 Very Positive mention(s)
0 Positive mention(s)
9 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Rhythm Pharmaceuticals
2 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Taysha Gene Therapies has a beta of 1.19, meaning that its stock price is 19% more volatile than the broader market. Comparatively, Rhythm Pharmaceuticals has a beta of 1.91, meaning that its stock price is 91% more volatile than the broader market.

Summary

Taysha Gene Therapies beats Rhythm Pharmaceuticals on 12 of the 17 factors compared between the two stocks.

How does Taysha Gene Therapies compare to Lantheus?

Lantheus (NASDAQ:LNTH) and Taysha Gene Therapies (NASDAQ:TSHA) are both medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their risk, analyst recommendations, valuation, earnings, institutional ownership, profitability, media sentiment and dividends.

Lantheus has a net margin of 18.05% compared to Taysha Gene Therapies' net margin of 0.00%. Lantheus' return on equity of 29.32% beat Taysha Gene Therapies' return on equity.

Company Net Margins Return on Equity Return on Assets
Lantheus18.05% 29.32% 15.00%
Taysha Gene Therapies N/A -56.07%-40.16%

Lantheus presently has a consensus target price of $101.86, suggesting a potential downside of 7.23%. Taysha Gene Therapies has a consensus target price of $12.38, suggesting a potential upside of 95.34%. Given Taysha Gene Therapies' stronger consensus rating and higher possible upside, analysts clearly believe Taysha Gene Therapies is more favorable than Lantheus.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lantheus
0 Sell rating(s)
3 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.73
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
11 Buy rating(s)
2 Strong Buy rating(s)
3.00

99.1% of Lantheus shares are held by institutional investors. Comparatively, 77.7% of Taysha Gene Therapies shares are held by institutional investors. 1.7% of Lantheus shares are held by company insiders. Comparatively, 3.8% of Taysha Gene Therapies shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Lantheus has a beta of -0.03, suggesting that its stock price is 103% less volatile than the broader market. Comparatively, Taysha Gene Therapies has a beta of 1.19, suggesting that its stock price is 19% more volatile than the broader market.

Lantheus has higher revenue and earnings than Taysha Gene Therapies. Taysha Gene Therapies is trading at a lower price-to-earnings ratio than Lantheus, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lantheus$1.54B4.64$233.56M$4.1526.46
Taysha Gene Therapies$9.77M186.48-$109M-$0.38N/A

In the previous week, Taysha Gene Therapies had 4 more articles in the media than Lantheus. MarketBeat recorded 15 mentions for Taysha Gene Therapies and 11 mentions for Lantheus. Taysha Gene Therapies' average media sentiment score of 0.44 beat Lantheus' score of -0.03 indicating that Taysha Gene Therapies is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lantheus
0 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Neutral
Taysha Gene Therapies
3 Very Positive mention(s)
0 Positive mention(s)
9 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Taysha Gene Therapies beats Lantheus on 9 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding TSHA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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TSHA vs. The Competition

MetricTaysha Gene TherapiesMED IndustryMedical SectorNASDAQ Exchange
Market Cap$1.82B$6.01B$7.04B$12.18B
Dividend YieldN/A0.63%2.66%6.24%
P/E Ratio-16.689.2326.1324.17
Price / Sales186.4823.86600.49118.58
Price / CashN/A8.9847.9555.62
Price / Book7.044.3310.786.36
Net Income-$109M$99.67M$3.58B$337.99M
7 Day Performance-1.25%7.76%2.22%0.10%
1 Month Performance7.09%4.03%-0.09%-1.28%
1 Year Performance166.39%130.64%34.39%27.68%

Taysha Gene Therapies Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
TSHA
Taysha Gene Therapies
3.0648 of 5 stars
$6.34
+2.1%
$12.38
+95.3%
+166.4%$1.82B$9.77MN/A180
HHH
Howard Hughes
2.6835 of 5 stars
$66.81
-0.1%
$85.00
+27.2%
+6.6%$3.99B$1.51B32.75608
PTGX
Protagonist Therapeutics
0.9554 of 5 stars
$115.03
+1.9%
$115.21
+0.2%
+118.9%$7.26B$46.02MN/A120
IMVT
Immunovant
0.7441 of 5 stars
$38.10
+7.8%
$37.33
-2.0%
+141.3%$7.26BN/AN/A120
RYTM
Rhythm Pharmaceuticals
2.7297 of 5 stars
$101.39
+4.8%
$133.13
+31.3%
+75.1%$6.95B$217.17MN/A140

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This page (NASDAQ:TSHA) was last updated on 6/28/2026 by MarketBeat.com Staff.
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