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Taysha Gene Therapies (TSHA) Competitors

Taysha Gene Therapies logo
$3.62 -0.11 (-2.95%)
Closing price 10/16/2026 04:00 PM Eastern
Extended Trading
$3.67 +0.05 (+1.44%)
As of 10/16/2026 07:38 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

TSHA vs. HHH, CGON, ERAS, MIRM, and ORKA

Should you buy Taysha Gene Therapies stock or one of its competitors? Taysha Gene Therapies's main competitors and comparable companies include Howard Hughes (HHH), CG Oncology (CGON), Erasca (ERAS), Mirum Pharmaceuticals (MIRM), and Oruka Therapeutics (ORKA). Companies are selected based on similarities in market, industry, and size.

How does Taysha Gene Therapies compare to Howard Hughes?

Taysha Gene Therapies (NASDAQ:TSHA) and Howard Hughes (NYSE:HHH) are related companies, but which is the superior investment? We will compare the two companies based on the strength of their analyst recommendations, profitability, risk, media sentiment, valuation, earnings, institutional ownership and dividends.

In the previous week, Howard Hughes had 7 more articles in the media than Taysha Gene Therapies. MarketBeat recorded 10 mentions for Howard Hughes and 3 mentions for Taysha Gene Therapies. Howard Hughes' average media sentiment score of 0.55 beat Taysha Gene Therapies' score of 0.41 indicating that Howard Hughes is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Taysha Gene Therapies
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Howard Hughes
2 Very Positive mention(s)
1 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Taysha Gene Therapies currently has a consensus target price of $12.77, indicating a potential upside of 252.74%. Howard Hughes has a consensus target price of $81.00, indicating a potential upside of 17.80%. Given Taysha Gene Therapies' stronger consensus rating and higher possible upside, analysts plainly believe Taysha Gene Therapies is more favorable than Howard Hughes.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
2 Strong Buy rating(s)
3.00
Howard Hughes
0 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.75

Howard Hughes has a net margin of 12.31% compared to Taysha Gene Therapies' net margin of 0.00%. Howard Hughes' return on equity of 7.51% beat Taysha Gene Therapies' return on equity.

Company Net Margins Return on Equity Return on Assets
Taysha Gene TherapiesN/A -56.19% -41.84%
Howard Hughes 12.31%7.51%2.41%

Taysha Gene Therapies has a beta of 1.19, suggesting that its share price is 19% more volatile than the broader market. Comparatively, Howard Hughes has a beta of 1.14, suggesting that its share price is 14% more volatile than the broader market.

77.7% of Taysha Gene Therapies shares are owned by institutional investors. Comparatively, 93.8% of Howard Hughes shares are owned by institutional investors. 3.5% of Taysha Gene Therapies shares are owned by insiders. Comparatively, 47.7% of Howard Hughes shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Howard Hughes has higher revenue and earnings than Taysha Gene Therapies. Taysha Gene Therapies is trading at a lower price-to-earnings ratio than Howard Hughes, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Taysha Gene Therapies$9.77M120.73-$109M-$0.42N/A
Howard Hughes$1.47B2.78$123.90M$4.9413.92

Summary

Howard Hughes beats Taysha Gene Therapies on 11 of the 17 factors compared between the two stocks.

How does Taysha Gene Therapies compare to CG Oncology?

CG Oncology (NASDAQ:CGON) and Taysha Gene Therapies (NASDAQ:TSHA) are both healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their valuation, profitability, dividends, media sentiment, risk, institutional ownership, earnings and analyst recommendations.

26.6% of CG Oncology shares are owned by institutional investors. Comparatively, 77.7% of Taysha Gene Therapies shares are owned by institutional investors. 4.8% of CG Oncology shares are owned by company insiders. Comparatively, 3.5% of Taysha Gene Therapies shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

CG Oncology currently has a consensus target price of $87.50, suggesting a potential upside of 46.20%. Taysha Gene Therapies has a consensus target price of $12.77, suggesting a potential upside of 252.74%. Given Taysha Gene Therapies' stronger consensus rating and higher possible upside, analysts clearly believe Taysha Gene Therapies is more favorable than CG Oncology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
CG Oncology
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.70
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
2 Strong Buy rating(s)
3.00

Taysha Gene Therapies has higher revenue and earnings than CG Oncology. CG Oncology is trading at a lower price-to-earnings ratio than Taysha Gene Therapies, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
CG Oncology$4.04M1,313.14-$160.99M-$2.69N/A
Taysha Gene Therapies$9.77M120.73-$109M-$0.42N/A

In the previous week, CG Oncology had 5 more articles in the media than Taysha Gene Therapies. MarketBeat recorded 8 mentions for CG Oncology and 3 mentions for Taysha Gene Therapies. Taysha Gene Therapies' average media sentiment score of 0.41 beat CG Oncology's score of 0.21 indicating that Taysha Gene Therapies is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
CG Oncology
1 Very Positive mention(s)
0 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Taysha Gene Therapies
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Taysha Gene Therapies has a net margin of 0.00% compared to CG Oncology's net margin of -3,602.68%. CG Oncology's return on equity of -25.20% beat Taysha Gene Therapies' return on equity.

Company Net Margins Return on Equity Return on Assets
CG Oncology-3,602.68% -25.20% -23.98%
Taysha Gene Therapies N/A -56.19%-41.84%

CG Oncology has a beta of 0.28, meaning that its share price is 72% less volatile than the broader market. Comparatively, Taysha Gene Therapies has a beta of 1.19, meaning that its share price is 19% more volatile than the broader market.

Summary

Taysha Gene Therapies beats CG Oncology on 12 of the 17 factors compared between the two stocks.

How does Taysha Gene Therapies compare to Erasca?

Taysha Gene Therapies (NASDAQ:TSHA) and Erasca (NASDAQ:ERAS) are both healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their valuation, analyst recommendations, media sentiment, earnings, profitability, institutional ownership, dividends and risk.

In the previous week, Erasca had 1 more articles in the media than Taysha Gene Therapies. MarketBeat recorded 4 mentions for Erasca and 3 mentions for Taysha Gene Therapies. Erasca's average media sentiment score of 0.90 beat Taysha Gene Therapies' score of 0.41 indicating that Erasca is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Taysha Gene Therapies
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Erasca
1 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Taysha Gene Therapies currently has a consensus price target of $12.77, suggesting a potential upside of 252.74%. Erasca has a consensus price target of $22.09, suggesting a potential upside of 64.98%. Given Taysha Gene Therapies' stronger consensus rating and higher possible upside, analysts plainly believe Taysha Gene Therapies is more favorable than Erasca.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
2 Strong Buy rating(s)
3.00
Erasca
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.64

Taysha Gene Therapies has a beta of 1.19, suggesting that its stock price is 19% more volatile than the broader market. Comparatively, Erasca has a beta of 0.61, suggesting that its stock price is 39% less volatile than the broader market.

77.7% of Taysha Gene Therapies shares are owned by institutional investors. Comparatively, 67.8% of Erasca shares are owned by institutional investors. 3.5% of Taysha Gene Therapies shares are owned by company insiders. Comparatively, 14.2% of Erasca shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Erasca's return on equity of -38.43% beat Taysha Gene Therapies' return on equity.

Company Net Margins Return on Equity Return on Assets
Taysha Gene TherapiesN/A -56.19% -41.84%
Erasca N/A -38.43%-32.05%

Taysha Gene Therapies has higher revenue and earnings than Erasca. Erasca is trading at a lower price-to-earnings ratio than Taysha Gene Therapies, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Taysha Gene Therapies$9.77M120.73-$109M-$0.42N/A
ErascaN/AN/A-$124.55M-$0.95N/A

Summary

Taysha Gene Therapies beats Erasca on 10 of the 15 factors compared between the two stocks.

How does Taysha Gene Therapies compare to Mirum Pharmaceuticals?

Mirum Pharmaceuticals (NASDAQ:MIRM) and Taysha Gene Therapies (NASDAQ:TSHA) are both healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their earnings, institutional ownership, valuation, profitability, risk, analyst recommendations, dividends and media sentiment.

77.7% of Taysha Gene Therapies shares are owned by institutional investors. 8.3% of Mirum Pharmaceuticals shares are owned by company insiders. Comparatively, 3.5% of Taysha Gene Therapies shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Mirum Pharmaceuticals currently has a consensus price target of $147.88, indicating a potential upside of 84.52%. Taysha Gene Therapies has a consensus price target of $12.77, indicating a potential upside of 252.74%. Given Taysha Gene Therapies' stronger consensus rating and higher possible upside, analysts plainly believe Taysha Gene Therapies is more favorable than Mirum Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mirum Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.93
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
2 Strong Buy rating(s)
3.00

Mirum Pharmaceuticals has a beta of 0.61, suggesting that its share price is 39% less volatile than the broader market. Comparatively, Taysha Gene Therapies has a beta of 1.19, suggesting that its share price is 19% more volatile than the broader market.

Taysha Gene Therapies has a net margin of 0.00% compared to Mirum Pharmaceuticals' net margin of -139.18%. Mirum Pharmaceuticals' return on equity of -36.28% beat Taysha Gene Therapies' return on equity.

Company Net Margins Return on Equity Return on Assets
Mirum Pharmaceuticals-139.18% -36.28% -8.54%
Taysha Gene Therapies N/A -56.19%-41.84%

Mirum Pharmaceuticals has higher revenue and earnings than Taysha Gene Therapies. Taysha Gene Therapies is trading at a lower price-to-earnings ratio than Mirum Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mirum Pharmaceuticals$521.31M9.98-$23.36M-$14.55N/A
Taysha Gene Therapies$9.77M120.73-$109M-$0.42N/A

In the previous week, Mirum Pharmaceuticals had 25 more articles in the media than Taysha Gene Therapies. MarketBeat recorded 28 mentions for Mirum Pharmaceuticals and 3 mentions for Taysha Gene Therapies. Mirum Pharmaceuticals' average media sentiment score of 0.42 beat Taysha Gene Therapies' score of 0.41 indicating that Mirum Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mirum Pharmaceuticals
8 Very Positive mention(s)
4 Positive mention(s)
8 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Taysha Gene Therapies
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Mirum Pharmaceuticals and Taysha Gene Therapies tied by winning 8 of the 16 factors compared between the two stocks.

How does Taysha Gene Therapies compare to Oruka Therapeutics?

Oruka Therapeutics (NASDAQ:ORKA) and Taysha Gene Therapies (NASDAQ:TSHA) are both healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their institutional ownership, risk, valuation, dividends, analyst recommendations, media sentiment, earnings and profitability.

Oruka Therapeutics presently has a consensus price target of $128.91, indicating a potential upside of 79.21%. Taysha Gene Therapies has a consensus price target of $12.77, indicating a potential upside of 252.74%. Given Taysha Gene Therapies' stronger consensus rating and higher probable upside, analysts clearly believe Taysha Gene Therapies is more favorable than Oruka Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Oruka Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
2 Strong Buy rating(s)
3.00

Oruka Therapeutics' return on equity of -21.65% beat Taysha Gene Therapies' return on equity.

Company Net Margins Return on Equity Return on Assets
Oruka TherapeuticsN/A -21.65% -20.88%
Taysha Gene Therapies N/A -56.19%-41.84%

Oruka Therapeutics has higher earnings, but lower revenue than Taysha Gene Therapies. Oruka Therapeutics is trading at a lower price-to-earnings ratio than Taysha Gene Therapies, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Oruka TherapeuticsN/AN/A-$105.43M-$2.03N/A
Taysha Gene Therapies$9.77M120.73-$109M-$0.42N/A

56.4% of Oruka Therapeutics shares are held by institutional investors. Comparatively, 77.7% of Taysha Gene Therapies shares are held by institutional investors. 23.5% of Oruka Therapeutics shares are held by company insiders. Comparatively, 3.5% of Taysha Gene Therapies shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

In the previous week, Oruka Therapeutics had 4 more articles in the media than Taysha Gene Therapies. MarketBeat recorded 7 mentions for Oruka Therapeutics and 3 mentions for Taysha Gene Therapies. Oruka Therapeutics' average media sentiment score of 0.65 beat Taysha Gene Therapies' score of 0.41 indicating that Oruka Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Oruka Therapeutics
4 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Taysha Gene Therapies
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Oruka Therapeutics has a beta of -0.37, meaning that its share price is 137% less volatile than the broader market. Comparatively, Taysha Gene Therapies has a beta of 1.19, meaning that its share price is 19% more volatile than the broader market.

Summary

Taysha Gene Therapies beats Oruka Therapeutics on 8 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding TSHA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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TSHA vs. The Competition

MetricTaysha Gene TherapiesBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$1.22B$3.95B$7.45B$12.95B
Dividend YieldN/A3.64%2.50%27.63%
P/E Ratio-8.6212.55275.0024.84
Price / Sales120.731,175.03571.5476.68
Price / CashN/A122.1076.5451.88
Price / Book4.0215.9410.315.85
Net Income-$109M-$22.69M$3.51B$381.63M
7 Day Performance-19.38%-8.71%-5.47%-5.04%
1 Month Performance-29.84%-15.43%-9.66%-7.99%
1 Year Performance-23.31%1.39%0.73%-5.68%

Taysha Gene Therapies Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
TSHA
Taysha Gene Therapies
2.1445 of 5 stars
$3.62
-2.9%
$12.77
+252.7%
-28.7%$1.22B$9.77MN/A99
HHH
Howard Hughes
3.4479 of 5 stars
$72.33
-1.9%
$81.00
+12.0%
-13.7%$4.40B$1.47B14.64500
CGON
CG Oncology
3.6703 of 5 stars
$63.13
-1.1%
$87.50
+38.6%
+43.0%$5.66B$4.04MN/A142
ERAS
Erasca
2.7565 of 5 stars
$15.46
-3.6%
$22.09
+42.9%
+429.2%$5.61BN/AN/A103
MIRM
Mirum Pharmaceuticals
3.153 of 5 stars
$86.06
+0.1%
$146.13
+69.8%
+7.7%$5.58B$521.31MN/A433

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This page (NASDAQ:TSHA) was last updated on 10/17/2026 by MarketBeat.com Staff.
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