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C4 Therapeutics (CCCC) Competitors

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$4.30 0.00 (0.00%)
Closing price 07/2/2026 04:00 PM Eastern
Extended Trading
$4.26 -0.04 (-1.05%)
As of 07/2/2026 07:50 PM Eastern
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CCCC vs. GLUE, NUVB, ATAI, TSHA, and SION

Should you buy C4 Therapeutics stock or one of its competitors? MarketBeat compares C4 Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with C4 Therapeutics include Monte Rosa Therapeutics (GLUE), Nuvation Bio (NUVB), Atai Beckley (ATAI), Taysha Gene Therapies (TSHA), and Sionna Therapeutics (SION). These companies are all part of the "pharmaceutical products" industry.

How does C4 Therapeutics compare to Monte Rosa Therapeutics?

Monte Rosa Therapeutics (NASDAQ:GLUE) and C4 Therapeutics (NASDAQ:CCCC) are both medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their earnings, valuation, profitability, analyst recommendations, dividends, media sentiment, institutional ownership and risk.

Monte Rosa Therapeutics has higher revenue and earnings than C4 Therapeutics. Monte Rosa Therapeutics is trading at a lower price-to-earnings ratio than C4 Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Monte Rosa Therapeutics$123.67M16.54-$38.63M-$1.48N/A
C4 Therapeutics$35.95M13.23-$104.99M-$1.19N/A

In the previous week, Monte Rosa Therapeutics had 7 more articles in the media than C4 Therapeutics. MarketBeat recorded 9 mentions for Monte Rosa Therapeutics and 2 mentions for C4 Therapeutics. C4 Therapeutics' average media sentiment score of 0.89 beat Monte Rosa Therapeutics' score of 0.08 indicating that C4 Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Monte Rosa Therapeutics
5 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
C4 Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Monte Rosa Therapeutics has a beta of 1.56, suggesting that its stock price is 56% more volatile than the broader market. Comparatively, C4 Therapeutics has a beta of 2.9, suggesting that its stock price is 190% more volatile than the broader market.

Monte Rosa Therapeutics currently has a consensus target price of $33.33, suggesting a potential upside of 37.68%. C4 Therapeutics has a consensus target price of $7.75, suggesting a potential upside of 80.23%. Given C4 Therapeutics' higher probable upside, analysts clearly believe C4 Therapeutics is more favorable than Monte Rosa Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Monte Rosa Therapeutics
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.67
C4 Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57

80.0% of Monte Rosa Therapeutics shares are owned by institutional investors. Comparatively, 78.8% of C4 Therapeutics shares are owned by institutional investors. 6.4% of Monte Rosa Therapeutics shares are owned by insiders. Comparatively, 5.6% of C4 Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

C4 Therapeutics has a net margin of -297.76% compared to Monte Rosa Therapeutics' net margin of -302.69%. Monte Rosa Therapeutics' return on equity of -40.99% beat C4 Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Monte Rosa Therapeutics-302.69% -40.99% -25.94%
C4 Therapeutics -297.76%-50.68%-33.22%

Summary

Monte Rosa Therapeutics beats C4 Therapeutics on 10 of the 16 factors compared between the two stocks.

How does C4 Therapeutics compare to Nuvation Bio?

Nuvation Bio (NYSE:NUVB) and C4 Therapeutics (NASDAQ:CCCC) are both small-cap medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their earnings, valuation, dividends, profitability, risk, analyst recommendations, institutional ownership and media sentiment.

Nuvation Bio currently has a consensus price target of $12.50, indicating a potential upside of 119.88%. C4 Therapeutics has a consensus price target of $7.75, indicating a potential upside of 80.23%. Given Nuvation Bio's higher probable upside, equities research analysts clearly believe Nuvation Bio is more favorable than C4 Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Nuvation Bio
2 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.55
C4 Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57

Nuvation Bio has a beta of 1.52, meaning that its stock price is 52% more volatile than the broader market. Comparatively, C4 Therapeutics has a beta of 2.9, meaning that its stock price is 190% more volatile than the broader market.

In the previous week, Nuvation Bio had 2 more articles in the media than C4 Therapeutics. MarketBeat recorded 4 mentions for Nuvation Bio and 2 mentions for C4 Therapeutics. C4 Therapeutics' average media sentiment score of 0.89 beat Nuvation Bio's score of 0.63 indicating that C4 Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Nuvation Bio
1 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
C4 Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

61.7% of Nuvation Bio shares are owned by institutional investors. Comparatively, 78.8% of C4 Therapeutics shares are owned by institutional investors. 30.1% of Nuvation Bio shares are owned by company insiders. Comparatively, 5.6% of C4 Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Nuvation Bio has a net margin of -102.06% compared to C4 Therapeutics' net margin of -297.76%. Nuvation Bio's return on equity of -44.10% beat C4 Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Nuvation Bio-102.06% -44.10% -23.80%
C4 Therapeutics -297.76%-50.68%-33.22%

C4 Therapeutics has lower revenue, but higher earnings than Nuvation Bio. Nuvation Bio is trading at a lower price-to-earnings ratio than C4 Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Nuvation Bio$62.90M31.47-$204.63M-$0.43N/A
C4 Therapeutics$35.95M13.23-$104.99M-$1.19N/A

Summary

Nuvation Bio beats C4 Therapeutics on 10 of the 16 factors compared between the two stocks.

How does C4 Therapeutics compare to Atai Beckley?

C4 Therapeutics (NASDAQ:CCCC) and Atai Beckley (NASDAQ:ATAI) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their valuation, profitability, institutional ownership, media sentiment, earnings, risk, dividends and analyst recommendations.

In the previous week, C4 Therapeutics and C4 Therapeutics both had 2 articles in the media. C4 Therapeutics' average media sentiment score of 0.89 beat Atai Beckley's score of 0.89 indicating that C4 Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
C4 Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Atai Beckley
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

C4 Therapeutics has a beta of 2.9, indicating that its share price is 190% more volatile than the broader market. Comparatively, Atai Beckley has a beta of 1.56, indicating that its share price is 56% more volatile than the broader market.

C4 Therapeutics currently has a consensus target price of $7.75, suggesting a potential upside of 80.23%. Atai Beckley has a consensus target price of $16.00, suggesting a potential upside of 208.29%. Given Atai Beckley's stronger consensus rating and higher probable upside, analysts clearly believe Atai Beckley is more favorable than C4 Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
C4 Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57
Atai Beckley
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91

C4 Therapeutics has a net margin of -297.76% compared to Atai Beckley's net margin of -19,019.44%. C4 Therapeutics' return on equity of -50.68% beat Atai Beckley's return on equity.

Company Net Margins Return on Equity Return on Assets
C4 Therapeutics-297.76% -50.68% -33.22%
Atai Beckley -19,019.44%-89.79%-63.58%

C4 Therapeutics has higher revenue and earnings than Atai Beckley. C4 Therapeutics is trading at a lower price-to-earnings ratio than Atai Beckley, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
C4 Therapeutics$35.95M13.23-$104.99M-$1.19N/A
Atai Beckley$4.09M467.19-$660.05M-$2.23N/A

78.8% of C4 Therapeutics shares are held by institutional investors. Comparatively, 28.4% of Atai Beckley shares are held by institutional investors. 5.6% of C4 Therapeutics shares are held by insiders. Comparatively, 26.8% of Atai Beckley shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Summary

C4 Therapeutics beats Atai Beckley on 9 of the 16 factors compared between the two stocks.

How does C4 Therapeutics compare to Taysha Gene Therapies?

Taysha Gene Therapies (NASDAQ:TSHA) and C4 Therapeutics (NASDAQ:CCCC) are both small-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their analyst recommendations, institutional ownership, media sentiment, earnings, dividends, profitability, valuation and risk.

In the previous week, Taysha Gene Therapies had 3 more articles in the media than C4 Therapeutics. MarketBeat recorded 5 mentions for Taysha Gene Therapies and 2 mentions for C4 Therapeutics. C4 Therapeutics' average media sentiment score of 0.89 beat Taysha Gene Therapies' score of 0.49 indicating that C4 Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Taysha Gene Therapies
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
C4 Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

77.7% of Taysha Gene Therapies shares are owned by institutional investors. Comparatively, 78.8% of C4 Therapeutics shares are owned by institutional investors. 3.8% of Taysha Gene Therapies shares are owned by company insiders. Comparatively, 5.6% of C4 Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Taysha Gene Therapies has a beta of 1.17, indicating that its share price is 17% more volatile than the broader market. Comparatively, C4 Therapeutics has a beta of 2.9, indicating that its share price is 190% more volatile than the broader market.

Taysha Gene Therapies currently has a consensus price target of $12.62, indicating a potential upside of 93.19%. C4 Therapeutics has a consensus price target of $7.75, indicating a potential upside of 80.23%. Given Taysha Gene Therapies' stronger consensus rating and higher possible upside, equities analysts plainly believe Taysha Gene Therapies is more favorable than C4 Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
11 Buy rating(s)
2 Strong Buy rating(s)
3.00
C4 Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57

C4 Therapeutics has higher revenue and earnings than Taysha Gene Therapies. Taysha Gene Therapies is trading at a lower price-to-earnings ratio than C4 Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Taysha Gene Therapies$9.77M192.06-$109M-$0.38N/A
C4 Therapeutics$35.95M13.23-$104.99M-$1.19N/A

Taysha Gene Therapies has a net margin of 0.00% compared to C4 Therapeutics' net margin of -297.76%. C4 Therapeutics' return on equity of -50.68% beat Taysha Gene Therapies' return on equity.

Company Net Margins Return on Equity Return on Assets
Taysha Gene TherapiesN/A -56.07% -40.16%
C4 Therapeutics -297.76%-50.68%-33.22%

Summary

C4 Therapeutics beats Taysha Gene Therapies on 9 of the 17 factors compared between the two stocks.

How does C4 Therapeutics compare to Sionna Therapeutics?

C4 Therapeutics (NASDAQ:CCCC) and Sionna Therapeutics (NASDAQ:SION) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, valuation, profitability, risk, institutional ownership, analyst recommendations, earnings and dividends.

Sionna Therapeutics has a net margin of 0.00% compared to C4 Therapeutics' net margin of -297.76%. Sionna Therapeutics' return on equity of -27.31% beat C4 Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
C4 Therapeutics-297.76% -50.68% -33.22%
Sionna Therapeutics N/A -27.31%-25.88%

78.8% of C4 Therapeutics shares are owned by institutional investors. 5.6% of C4 Therapeutics shares are owned by insiders. Comparatively, 5.1% of Sionna Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

In the previous week, Sionna Therapeutics had 6 more articles in the media than C4 Therapeutics. MarketBeat recorded 8 mentions for Sionna Therapeutics and 2 mentions for C4 Therapeutics. C4 Therapeutics' average media sentiment score of 0.89 beat Sionna Therapeutics' score of 0.29 indicating that C4 Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
C4 Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Sionna Therapeutics
3 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

C4 Therapeutics has a beta of 2.9, indicating that its stock price is 190% more volatile than the broader market. Comparatively, Sionna Therapeutics has a beta of 1.33, indicating that its stock price is 33% more volatile than the broader market.

C4 Therapeutics currently has a consensus price target of $7.75, suggesting a potential upside of 80.23%. Sionna Therapeutics has a consensus price target of $53.22, suggesting a potential upside of 20.99%. Given C4 Therapeutics' higher probable upside, analysts clearly believe C4 Therapeutics is more favorable than Sionna Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
C4 Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57
Sionna Therapeutics
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
2.85

Sionna Therapeutics has lower revenue, but higher earnings than C4 Therapeutics. Sionna Therapeutics is trading at a lower price-to-earnings ratio than C4 Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
C4 Therapeutics$35.95M13.23-$104.99M-$1.19N/A
Sionna TherapeuticsN/AN/A-$75.27M-$1.93N/A

Summary

C4 Therapeutics and Sionna Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding CCCC and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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CCCC vs. The Competition

MetricC4 TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$475.44M$3.78B$7.18B$12.47B
Dividend YieldN/A2.16%2.66%6.51%
P/E Ratio-3.6121.6128.0224.70
Price / Sales13.23338.16537.0097.28
Price / CashN/A147.1249.2657.09
Price / Book1.628.6610.966.46
Net Income-$104.99M$23.81M$3.57B$337.01M
7 Day Performance0.94%3.39%2.12%1.69%
1 Month Performance11.69%10.81%5.25%3.81%
1 Year Performance188.59%62.61%33.29%23.90%

C4 Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
CCCC
C4 Therapeutics
1.8401 of 5 stars
$4.30
flat
$7.75
+80.2%
+188.6%$475.44M$35.95MN/A150
GLUE
Monte Rosa Therapeutics
1.9885 of 5 stars
$23.96
+0.3%
$33.33
+39.1%
+379.9%$2.03B$123.67MN/A90
NUVB
Nuvation Bio
4.0321 of 5 stars
$5.79
+3.1%
$12.50
+116.1%
+172.7%$2.02B$143.05MN/A60
ATAI
Atai Beckley
3.5663 of 5 stars
$5.49
+2.3%
$16.00
+191.7%
+87.0%$2.00B$3.49MN/A80
TSHA
Taysha Gene Therapies
3.1774 of 5 stars
$6.92
+2.8%
$12.62
+82.3%
+172.1%$1.98B$9.77MN/A180

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This page (NASDAQ:CCCC) was last updated on 7/5/2026 by MarketBeat.com Staff.
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