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C4 Therapeutics (CCCC) Competitors

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$3.90 +0.03 (+0.78%)
Closing price 06/12/2026 04:00 PM Eastern
Extended Trading
$3.93 +0.03 (+0.79%)
As of 06/12/2026 07:00 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

CCCC vs. AGIO, TSHA, AAPG, CMPS, and TYRA

Should you buy C4 Therapeutics stock or one of its competitors? MarketBeat compares C4 Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with C4 Therapeutics include Agios Pharmaceuticals (AGIO), Taysha Gene Therapies (TSHA), Ascentage Pharma Group International (AAPG), Compass Pathways (CMPS), and Tyra Biosciences (TYRA). These companies are all part of the "pharmaceutical products" industry.

How does C4 Therapeutics compare to Agios Pharmaceuticals?

Agios Pharmaceuticals (NASDAQ:AGIO) and C4 Therapeutics (NASDAQ:CCCC) are both small-cap medical companies, but which is the superior stock? We will contrast the two businesses based on the strength of their valuation, institutional ownership, risk, dividends, earnings, profitability, media sentiment and analyst recommendations.

78.8% of C4 Therapeutics shares are owned by institutional investors. 5.4% of Agios Pharmaceuticals shares are owned by company insiders. Comparatively, 5.6% of C4 Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Agios Pharmaceuticals currently has a consensus price target of $40.89, indicating a potential upside of 38.79%. C4 Therapeutics has a consensus price target of $7.75, indicating a potential upside of 98.72%. Given C4 Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe C4 Therapeutics is more favorable than Agios Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Agios Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.45
C4 Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57

Agios Pharmaceuticals has a beta of 0.59, indicating that its share price is 41% less volatile than the broader market. Comparatively, C4 Therapeutics has a beta of 2.92, indicating that its share price is 192% more volatile than the broader market.

In the previous week, Agios Pharmaceuticals had 8 more articles in the media than C4 Therapeutics. MarketBeat recorded 12 mentions for Agios Pharmaceuticals and 4 mentions for C4 Therapeutics. Agios Pharmaceuticals' average media sentiment score of 0.76 beat C4 Therapeutics' score of 0.24 indicating that Agios Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Agios Pharmaceuticals
5 Very Positive mention(s)
2 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
C4 Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

C4 Therapeutics has lower revenue, but higher earnings than Agios Pharmaceuticals. Agios Pharmaceuticals is trading at a lower price-to-earnings ratio than C4 Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Agios Pharmaceuticals$54.03M32.43-$412.78M-$7.25N/A
C4 Therapeutics$34.86M12.37-$104.99M-$1.19N/A

C4 Therapeutics has a net margin of -297.76% compared to Agios Pharmaceuticals' net margin of -639.84%. Agios Pharmaceuticals' return on equity of -34.11% beat C4 Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Agios Pharmaceuticals-639.84% -34.11% -31.66%
C4 Therapeutics -297.76%-50.68%-33.22%

Summary

C4 Therapeutics beats Agios Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does C4 Therapeutics compare to Taysha Gene Therapies?

C4 Therapeutics (NASDAQ:CCCC) and Taysha Gene Therapies (NASDAQ:TSHA) are both small-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their analyst recommendations, profitability, valuation, risk, earnings, media sentiment, institutional ownership and dividends.

Taysha Gene Therapies has a net margin of 0.00% compared to C4 Therapeutics' net margin of -297.76%. C4 Therapeutics' return on equity of -50.68% beat Taysha Gene Therapies' return on equity.

Company Net Margins Return on Equity Return on Assets
C4 Therapeutics-297.76% -50.68% -33.22%
Taysha Gene Therapies N/A -56.07%-40.16%

78.8% of C4 Therapeutics shares are held by institutional investors. Comparatively, 77.7% of Taysha Gene Therapies shares are held by institutional investors. 5.6% of C4 Therapeutics shares are held by company insiders. Comparatively, 3.8% of Taysha Gene Therapies shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

C4 Therapeutics has a beta of 2.92, indicating that its stock price is 192% more volatile than the broader market. Comparatively, Taysha Gene Therapies has a beta of 1.19, indicating that its stock price is 19% more volatile than the broader market.

In the previous week, C4 Therapeutics had 1 more articles in the media than Taysha Gene Therapies. MarketBeat recorded 4 mentions for C4 Therapeutics and 3 mentions for Taysha Gene Therapies. Taysha Gene Therapies' average media sentiment score of 0.94 beat C4 Therapeutics' score of 0.24 indicating that Taysha Gene Therapies is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
C4 Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Taysha Gene Therapies
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

C4 Therapeutics has higher revenue and earnings than Taysha Gene Therapies. Taysha Gene Therapies is trading at a lower price-to-earnings ratio than C4 Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
C4 Therapeutics$34.86M12.37-$104.99M-$1.19N/A
Taysha Gene Therapies$7.47M219.63-$109M-$0.38N/A

C4 Therapeutics currently has a consensus price target of $7.75, suggesting a potential upside of 98.72%. Taysha Gene Therapies has a consensus price target of $11.64, suggesting a potential upside of 103.79%. Given Taysha Gene Therapies' stronger consensus rating and higher probable upside, analysts clearly believe Taysha Gene Therapies is more favorable than C4 Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
C4 Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57
Taysha Gene Therapies
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
2 Strong Buy rating(s)
3.00

Summary

C4 Therapeutics beats Taysha Gene Therapies on 9 of the 17 factors compared between the two stocks.

How does C4 Therapeutics compare to Ascentage Pharma Group International?

Ascentage Pharma Group International (NASDAQ:AAPG) and C4 Therapeutics (NASDAQ:CCCC) are both small-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their media sentiment, analyst recommendations, earnings, risk, profitability, institutional ownership, dividends and valuation.

78.8% of C4 Therapeutics shares are owned by institutional investors. 5.6% of C4 Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

C4 Therapeutics has lower revenue, but higher earnings than Ascentage Pharma Group International.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ascentage Pharma Group International$574.12M2.86-$177.71MN/AN/A
C4 Therapeutics$34.86M12.37-$104.99M-$1.19N/A

Ascentage Pharma Group International presently has a consensus price target of $46.43, indicating a potential upside of 163.80%. C4 Therapeutics has a consensus price target of $7.75, indicating a potential upside of 98.72%. Given Ascentage Pharma Group International's stronger consensus rating and higher probable upside, equities analysts plainly believe Ascentage Pharma Group International is more favorable than C4 Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ascentage Pharma Group International
0 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.20
C4 Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57

Ascentage Pharma Group International has a net margin of 0.00% compared to C4 Therapeutics' net margin of -297.76%. Ascentage Pharma Group International's return on equity of 0.00% beat C4 Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Ascentage Pharma Group InternationalN/A N/A N/A
C4 Therapeutics -297.76%-50.68%-33.22%

Ascentage Pharma Group International has a beta of -0.05, indicating that its stock price is 105% less volatile than the broader market. Comparatively, C4 Therapeutics has a beta of 2.92, indicating that its stock price is 192% more volatile than the broader market.

In the previous week, Ascentage Pharma Group International had 1 more articles in the media than C4 Therapeutics. MarketBeat recorded 5 mentions for Ascentage Pharma Group International and 4 mentions for C4 Therapeutics. Ascentage Pharma Group International's average media sentiment score of 0.62 beat C4 Therapeutics' score of 0.24 indicating that Ascentage Pharma Group International is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ascentage Pharma Group International
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
C4 Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Ascentage Pharma Group International beats C4 Therapeutics on 10 of the 15 factors compared between the two stocks.

How does C4 Therapeutics compare to Compass Pathways?

C4 Therapeutics (NASDAQ:CCCC) and Compass Pathways (NASDAQ:CMPS) are both small-cap medical companies, but which is the superior stock? We will contrast the two businesses based on the strength of their dividends, valuation, risk, profitability, media sentiment, analyst recommendations, earnings and institutional ownership.

C4 Therapeutics currently has a consensus target price of $7.75, suggesting a potential upside of 98.72%. Compass Pathways has a consensus target price of $21.36, suggesting a potential upside of 76.85%. Given C4 Therapeutics' higher probable upside, analysts clearly believe C4 Therapeutics is more favorable than Compass Pathways.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
C4 Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57
Compass Pathways
1 Sell rating(s)
1 Hold rating(s)
10 Buy rating(s)
2 Strong Buy rating(s)
2.93

In the previous week, C4 Therapeutics had 2 more articles in the media than Compass Pathways. MarketBeat recorded 4 mentions for C4 Therapeutics and 2 mentions for Compass Pathways. Compass Pathways' average media sentiment score of 1.75 beat C4 Therapeutics' score of 0.24 indicating that Compass Pathways is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
C4 Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Compass Pathways
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Compass Pathways has a net margin of 0.00% compared to C4 Therapeutics' net margin of -297.76%. Compass Pathways' return on equity of -31.07% beat C4 Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
C4 Therapeutics-297.76% -50.68% -33.22%
Compass Pathways N/A -31.07%-11.40%

78.8% of C4 Therapeutics shares are owned by institutional investors. Comparatively, 46.2% of Compass Pathways shares are owned by institutional investors. 5.6% of C4 Therapeutics shares are owned by company insiders. Comparatively, 2.8% of Compass Pathways shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

C4 Therapeutics has a beta of 2.92, indicating that its stock price is 192% more volatile than the broader market. Comparatively, Compass Pathways has a beta of 2.5, indicating that its stock price is 150% more volatile than the broader market.

C4 Therapeutics has higher revenue and earnings than Compass Pathways. Compass Pathways is trading at a lower price-to-earnings ratio than C4 Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
C4 Therapeutics$34.86M12.37-$104.99M-$1.19N/A
Compass PathwaysN/AN/A-$287.86M-$3.15N/A

Summary

C4 Therapeutics beats Compass Pathways on 9 of the 16 factors compared between the two stocks.

How does C4 Therapeutics compare to Tyra Biosciences?

C4 Therapeutics (NASDAQ:CCCC) and Tyra Biosciences (NASDAQ:TYRA) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their dividends, valuation, media sentiment, earnings, analyst recommendations, institutional ownership, profitability and risk.

C4 Therapeutics has a beta of 2.92, meaning that its share price is 192% more volatile than the broader market. Comparatively, Tyra Biosciences has a beta of 0.75, meaning that its share price is 25% less volatile than the broader market.

C4 Therapeutics has higher revenue and earnings than Tyra Biosciences. Tyra Biosciences is trading at a lower price-to-earnings ratio than C4 Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
C4 Therapeutics$34.86M12.37-$104.99M-$1.19N/A
Tyra BiosciencesN/AN/A-$119.95M-$2.18N/A

78.8% of C4 Therapeutics shares are owned by institutional investors. Comparatively, 84.1% of Tyra Biosciences shares are owned by institutional investors. 5.6% of C4 Therapeutics shares are owned by company insiders. Comparatively, 12.5% of Tyra Biosciences shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

In the previous week, C4 Therapeutics had 2 more articles in the media than Tyra Biosciences. MarketBeat recorded 4 mentions for C4 Therapeutics and 2 mentions for Tyra Biosciences. Tyra Biosciences' average media sentiment score of 1.11 beat C4 Therapeutics' score of 0.24 indicating that Tyra Biosciences is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
C4 Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Tyra Biosciences
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Tyra Biosciences has a net margin of 0.00% compared to C4 Therapeutics' net margin of -297.76%. Tyra Biosciences' return on equity of -42.66% beat C4 Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
C4 Therapeutics-297.76% -50.68% -33.22%
Tyra Biosciences N/A -42.66%-39.79%

C4 Therapeutics currently has a consensus target price of $7.75, suggesting a potential upside of 98.72%. Tyra Biosciences has a consensus target price of $46.00, suggesting a potential upside of 70.43%. Given C4 Therapeutics' higher possible upside, analysts clearly believe C4 Therapeutics is more favorable than Tyra Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
C4 Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57
Tyra Biosciences
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.86

Summary

C4 Therapeutics and Tyra Biosciences tied by winning 8 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding CCCC and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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CCCC vs. The Competition

MetricC4 TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$431.21M$3.39B$6.72B$12.07B
Dividend YieldN/A2.25%2.67%5.67%
P/E Ratio-3.2819.8224.2424.42
Price / Sales12.37177.23481.0486.26
Price / CashN/A123.0443.5455.64
Price / Book1.478.3210.656.80
Net Income-$104.99M$23.94M$3.57B$338.00M
7 Day Performance1.30%3.53%0.84%2.68%
1 Month Performance7.44%-2.55%-0.34%1.56%
1 Year Performance132.14%44.82%25.40%30.59%

C4 Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
CCCC
C4 Therapeutics
1.846 of 5 stars
$3.90
+0.8%
$7.75
+98.7%
+132.1%$431.21M$34.86MN/A150
AGIO
Agios Pharmaceuticals
3.5367 of 5 stars
$27.37
-0.2%
$41.44
+51.4%
-14.1%$1.63B$54.03MN/A390
TSHA
Taysha Gene Therapies
3.2261 of 5 stars
$5.62
+3.4%
$11.64
+107.2%
+124.8%$1.61B$9.77MN/A180
AAPG
Ascentage Pharma Group International
4.3067 of 5 stars
$17.18
-0.1%
$46.67
+171.7%
-44.1%$1.60B$82.10MN/A600
CMPS
Compass Pathways
3.4927 of 5 stars
$11.72
-0.1%
$21.36
+82.3%
+175.2%$1.59BN/AN/A120

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This page (NASDAQ:CCCC) was last updated on 6/14/2026 by MarketBeat.com Staff.
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