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Fulcrum Therapeutics (FULC) Competitors

Fulcrum Therapeutics logo
$3.22 +0.08 (+2.55%)
Closing price 04:00 PM Eastern
Extended Trading
$3.18 -0.04 (-1.09%)
As of 07:15 PM Eastern
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FULC vs. NBTX, NRIX, ZYME, IOVA, and HRMY

Should you buy Fulcrum Therapeutics stock or one of its competitors? MarketBeat compares Fulcrum Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Fulcrum Therapeutics include Nanobiotix (NBTX), Nurix Therapeutics (NRIX), Zymeworks (ZYME), Iovance Biotherapeutics (IOVA), and Harmony Biosciences (HRMY). These companies are all part of the "pharmaceutical products" industry.

How does Fulcrum Therapeutics compare to Nanobiotix?

Fulcrum Therapeutics (NASDAQ:FULC) and Nanobiotix (NASDAQ:NBTX) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, risk, profitability, dividends, analyst recommendations, earnings, institutional ownership and valuation.

Fulcrum Therapeutics has a beta of 2.93, meaning that its stock price is 193% more volatile than the broader market. Comparatively, Nanobiotix has a beta of 0.74, meaning that its stock price is 26% less volatile than the broader market.

Nanobiotix's return on equity of 0.00% beat Fulcrum Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Fulcrum TherapeuticsN/A -27.80% -26.32%
Nanobiotix N/A N/A N/A

In the previous week, Fulcrum Therapeutics had 16 more articles in the media than Nanobiotix. MarketBeat recorded 19 mentions for Fulcrum Therapeutics and 3 mentions for Nanobiotix. Nanobiotix's average media sentiment score of 0.22 beat Fulcrum Therapeutics' score of -0.58 indicating that Nanobiotix is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Fulcrum Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
10 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Negative
Nanobiotix
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Nanobiotix has lower revenue, but higher earnings than Fulcrum Therapeutics.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fulcrum Therapeutics$80M2.68-$74.88M-$1.15N/A
Nanobiotix$36.87M46.32-$27.11MN/AN/A

Fulcrum Therapeutics currently has a consensus price target of $8.20, suggesting a potential upside of 154.66%. Nanobiotix has a consensus price target of $26.67, suggesting a potential downside of 24.24%. Given Fulcrum Therapeutics' higher probable upside, research analysts plainly believe Fulcrum Therapeutics is more favorable than Nanobiotix.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fulcrum Therapeutics
4 Sell rating(s)
7 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.75
Nanobiotix
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.50

89.8% of Fulcrum Therapeutics shares are owned by institutional investors. Comparatively, 38.8% of Nanobiotix shares are owned by institutional investors. 7.0% of Fulcrum Therapeutics shares are owned by company insiders. Comparatively, 3.5% of Nanobiotix shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Summary

Nanobiotix beats Fulcrum Therapeutics on 7 of the 13 factors compared between the two stocks.

How does Fulcrum Therapeutics compare to Nurix Therapeutics?

Fulcrum Therapeutics (NASDAQ:FULC) and Nurix Therapeutics (NASDAQ:NRIX) are both small-cap medical companies, but which is the superior stock? We will compare the two companies based on the strength of their media sentiment, risk, institutional ownership, valuation, profitability, dividends, earnings and analyst recommendations.

Fulcrum Therapeutics has a beta of 2.93, meaning that its stock price is 193% more volatile than the broader market. Comparatively, Nurix Therapeutics has a beta of 1.86, meaning that its stock price is 86% more volatile than the broader market.

Fulcrum Therapeutics has higher earnings, but lower revenue than Nurix Therapeutics. Nurix Therapeutics is trading at a lower price-to-earnings ratio than Fulcrum Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fulcrum Therapeutics$80M2.68-$74.88M-$1.15N/A
Nurix Therapeutics$83.98M19.06-$264.46M-$3.16N/A

89.8% of Fulcrum Therapeutics shares are owned by institutional investors. 7.0% of Fulcrum Therapeutics shares are owned by company insiders. Comparatively, 6.7% of Nurix Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

In the previous week, Fulcrum Therapeutics had 18 more articles in the media than Nurix Therapeutics. MarketBeat recorded 19 mentions for Fulcrum Therapeutics and 1 mentions for Nurix Therapeutics. Nurix Therapeutics' average media sentiment score of 1.89 beat Fulcrum Therapeutics' score of -0.58 indicating that Nurix Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
Fulcrum Therapeutics Negative
Nurix Therapeutics Very Positive

Fulcrum Therapeutics has a net margin of 0.00% compared to Nurix Therapeutics' net margin of -411.37%. Fulcrum Therapeutics' return on equity of -27.80% beat Nurix Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Fulcrum TherapeuticsN/A -27.80% -26.32%
Nurix Therapeutics -411.37%-64.21%-48.44%

Fulcrum Therapeutics currently has a consensus target price of $8.20, indicating a potential upside of 154.66%. Nurix Therapeutics has a consensus target price of $30.46, indicating a potential upside of 96.78%. Given Fulcrum Therapeutics' higher probable upside, equities analysts clearly believe Fulcrum Therapeutics is more favorable than Nurix Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fulcrum Therapeutics
4 Sell rating(s)
7 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.75
Nurix Therapeutics
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.93

Summary

Fulcrum Therapeutics beats Nurix Therapeutics on 11 of the 17 factors compared between the two stocks.

How does Fulcrum Therapeutics compare to Zymeworks?

Fulcrum Therapeutics (NASDAQ:FULC) and Zymeworks (NASDAQ:ZYME) are both small-cap pharmaceutical products companies, but which is the superior business? We will contrast the two companies based on the strength of their risk, analyst recommendations, media sentiment, earnings, valuation, institutional ownership, dividends and profitability.

In the previous week, Fulcrum Therapeutics had 15 more articles in the media than Zymeworks. MarketBeat recorded 19 mentions for Fulcrum Therapeutics and 4 mentions for Zymeworks. Zymeworks' average media sentiment score of 0.59 beat Fulcrum Therapeutics' score of -0.58 indicating that Zymeworks is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Fulcrum Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
10 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Negative
Zymeworks
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Fulcrum Therapeutics has a net margin of 0.00% compared to Zymeworks' net margin of -126.92%. Fulcrum Therapeutics' return on equity of -27.80% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Fulcrum TherapeuticsN/A -27.80% -26.32%
Zymeworks -126.92%-37.97%-25.31%

89.8% of Fulcrum Therapeutics shares are held by institutional investors. Comparatively, 92.9% of Zymeworks shares are held by institutional investors. 7.0% of Fulcrum Therapeutics shares are held by company insiders. Comparatively, 33.5% of Zymeworks shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Fulcrum Therapeutics has a beta of 2.93, meaning that its stock price is 193% more volatile than the broader market. Comparatively, Zymeworks has a beta of 1.15, meaning that its stock price is 15% more volatile than the broader market.

Fulcrum Therapeutics presently has a consensus target price of $8.20, suggesting a potential upside of 154.66%. Zymeworks has a consensus target price of $38.00, suggesting a potential upside of 56.06%. Given Fulcrum Therapeutics' higher possible upside, equities research analysts clearly believe Fulcrum Therapeutics is more favorable than Zymeworks.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fulcrum Therapeutics
4 Sell rating(s)
7 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.75
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91

Fulcrum Therapeutics has higher earnings, but lower revenue than Zymeworks. Zymeworks is trading at a lower price-to-earnings ratio than Fulcrum Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fulcrum Therapeutics$80M2.68-$74.88M-$1.15N/A
Zymeworks$105.96M16.78-$81.13M-$1.37N/A

Summary

Zymeworks beats Fulcrum Therapeutics on 9 of the 17 factors compared between the two stocks.

How does Fulcrum Therapeutics compare to Iovance Biotherapeutics?

Fulcrum Therapeutics (NASDAQ:FULC) and Iovance Biotherapeutics (NASDAQ:IOVA) are both small-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their valuation, earnings, dividends, institutional ownership, profitability, analyst recommendations, risk and media sentiment.

Fulcrum Therapeutics currently has a consensus price target of $8.20, indicating a potential upside of 154.66%. Iovance Biotherapeutics has a consensus price target of $8.43, indicating a potential upside of 122.39%. Given Fulcrum Therapeutics' higher probable upside, research analysts plainly believe Fulcrum Therapeutics is more favorable than Iovance Biotherapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fulcrum Therapeutics
4 Sell rating(s)
7 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.75
Iovance Biotherapeutics
2 Sell rating(s)
3 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.30

89.8% of Fulcrum Therapeutics shares are owned by institutional investors. Comparatively, 77.0% of Iovance Biotherapeutics shares are owned by institutional investors. 7.0% of Fulcrum Therapeutics shares are owned by insiders. Comparatively, 7.8% of Iovance Biotherapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Fulcrum Therapeutics has higher earnings, but lower revenue than Iovance Biotherapeutics. Iovance Biotherapeutics is trading at a lower price-to-earnings ratio than Fulcrum Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fulcrum Therapeutics$80M2.68-$74.88M-$1.15N/A
Iovance Biotherapeutics$263.50M6.42-$390.98M-$0.95N/A

Fulcrum Therapeutics has a beta of 2.93, indicating that its stock price is 193% more volatile than the broader market. Comparatively, Iovance Biotherapeutics has a beta of 0.74, indicating that its stock price is 26% less volatile than the broader market.

In the previous week, Iovance Biotherapeutics had 3 more articles in the media than Fulcrum Therapeutics. MarketBeat recorded 22 mentions for Iovance Biotherapeutics and 19 mentions for Fulcrum Therapeutics. Iovance Biotherapeutics' average media sentiment score of 0.29 beat Fulcrum Therapeutics' score of -0.58 indicating that Iovance Biotherapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Fulcrum Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
10 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Negative
Iovance Biotherapeutics
4 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Fulcrum Therapeutics has a net margin of 0.00% compared to Iovance Biotherapeutics' net margin of -123.92%. Fulcrum Therapeutics' return on equity of -27.80% beat Iovance Biotherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Fulcrum TherapeuticsN/A -27.80% -26.32%
Iovance Biotherapeutics -123.92%-50.17%-38.77%

Summary

Fulcrum Therapeutics and Iovance Biotherapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Fulcrum Therapeutics compare to Harmony Biosciences?

Harmony Biosciences (NASDAQ:HRMY) and Fulcrum Therapeutics (NASDAQ:FULC) are both small-cap medical companies, but which is the superior business? We will contrast the two companies based on the strength of their profitability, institutional ownership, dividends, valuation, media sentiment, analyst recommendations, earnings and risk.

Harmony Biosciences has a beta of 0.96, meaning that its stock price is 4% less volatile than the broader market. Comparatively, Fulcrum Therapeutics has a beta of 2.93, meaning that its stock price is 193% more volatile than the broader market.

86.2% of Harmony Biosciences shares are owned by institutional investors. Comparatively, 89.8% of Fulcrum Therapeutics shares are owned by institutional investors. 11.0% of Harmony Biosciences shares are owned by company insiders. Comparatively, 7.0% of Fulcrum Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Harmony Biosciences has higher revenue and earnings than Fulcrum Therapeutics. Fulcrum Therapeutics is trading at a lower price-to-earnings ratio than Harmony Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Harmony Biosciences$868.45M2.14$158.69M$2.4812.93
Fulcrum Therapeutics$80M2.68-$74.88M-$1.15N/A

In the previous week, Fulcrum Therapeutics had 18 more articles in the media than Harmony Biosciences. MarketBeat recorded 19 mentions for Fulcrum Therapeutics and 1 mentions for Harmony Biosciences. Harmony Biosciences' average media sentiment score of 1.34 beat Fulcrum Therapeutics' score of -0.58 indicating that Harmony Biosciences is being referred to more favorably in the media.

Company Overall Sentiment
Harmony Biosciences Positive
Fulcrum Therapeutics Negative

Harmony Biosciences currently has a consensus target price of $40.89, indicating a potential upside of 27.51%. Fulcrum Therapeutics has a consensus target price of $8.20, indicating a potential upside of 154.66%. Given Fulcrum Therapeutics' higher possible upside, analysts clearly believe Fulcrum Therapeutics is more favorable than Harmony Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Harmony Biosciences
1 Sell rating(s)
6 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.27
Fulcrum Therapeutics
4 Sell rating(s)
7 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.75

Harmony Biosciences has a net margin of 16.20% compared to Fulcrum Therapeutics' net margin of 0.00%. Harmony Biosciences' return on equity of 17.19% beat Fulcrum Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Harmony Biosciences16.20% 17.19% 11.99%
Fulcrum Therapeutics N/A -27.80%-26.32%

Summary

Harmony Biosciences beats Fulcrum Therapeutics on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding FULC and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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FULC vs. The Competition

MetricFulcrum TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$214.55M$3.28B$6.25B$12.42B
Dividend YieldN/A2.33%2.69%5.29%
P/E Ratio-2.8017.9322.2924.19
Price / Sales2.68324.62581.44138.36
Price / CashN/A116.2742.3157.88
Price / Book0.506.639.846.72
Net Income-$74.88M$24.20M$3.57B$337.19M
7 Day Performance-52.51%-3.24%-1.17%0.48%
1 Month Performance-56.28%0.53%3.84%5.06%
1 Year Performance-54.20%47.24%27.39%34.27%

Fulcrum Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
FULC
Fulcrum Therapeutics
2.1006 of 5 stars
$3.22
+2.5%
$8.20
+154.7%
-54.9%$214.55M$80MN/A100
NBTX
Nanobiotix
2.1917 of 5 stars
$36.34
-4.4%
$26.67
-26.6%
+789.2%$1.84B$29.64MN/A100
NRIX
Nurix Therapeutics
2.8828 of 5 stars
$16.40
-5.7%
$30.46
+85.8%
+34.8%$1.84B$71.78MN/A300
ZYME
Zymeworks
2.5532 of 5 stars
$24.13
-1.7%
$38.00
+57.5%
N/A$1.84B$81.26MN/A460
IOVA
Iovance Biotherapeutics
2.909 of 5 stars
$4.10
+3.4%
$8.43
+105.8%
+132.7%$1.83B$285.61MN/A500

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This page (NASDAQ:FULC) was last updated on 6/3/2026 by MarketBeat.com Staff.
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