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Mesoblast (MESO) Competitors

Mesoblast logo
$17.00 -0.43 (-2.47%)
As of 08/21/2026 04:00 PM Eastern

MESO vs. ALKS, APGE, IBRX, RYTM, and TGTX

Should you buy Mesoblast stock or one of its competitors? Mesoblast's main competitors and comparable companies include Alkermes (ALKS), Apogee Therapeutics (APGE), ImmunityBio (IBRX), Rhythm Pharmaceuticals (RYTM), and TG Therapeutics (TGTX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Mesoblast compare to Alkermes?

Mesoblast (NASDAQ:MESO) and Alkermes (NASDAQ:ALKS) are both mid-cap healthcare companies, but which is the better business? We will compare the two businesses based on the strength of their risk, media sentiment, valuation, institutional ownership, earnings, dividends, profitability and analyst recommendations.

1.4% of Mesoblast shares are held by institutional investors. Comparatively, 95.2% of Alkermes shares are held by institutional investors. 18.8% of Mesoblast shares are held by insiders. Comparatively, 4.6% of Alkermes shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Alkermes has a consensus target price of $54.56, suggesting a potential upside of 12.90%. Given Alkermes' stronger consensus rating and higher probable upside, analysts clearly believe Alkermes is more favorable than Mesoblast.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mesoblast
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Alkermes
1 Sell rating(s)
4 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.72

Alkermes has a net margin of 3.96% compared to Mesoblast's net margin of 0.00%. Alkermes' return on equity of 4.15% beat Mesoblast's return on equity.

Company Net Margins Return on Equity Return on Assets
MesoblastN/A N/A N/A
Alkermes 3.96%4.15%2.19%

In the previous week, Mesoblast had 4 more articles in the media than Alkermes. MarketBeat recorded 8 mentions for Mesoblast and 4 mentions for Alkermes. Alkermes' average media sentiment score of 1.02 beat Mesoblast's score of 0.01 indicating that Alkermes is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mesoblast
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Neutral
Alkermes
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Alkermes has higher revenue and earnings than Mesoblast. Mesoblast is trading at a lower price-to-earnings ratio than Alkermes, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mesoblast$17.20M128.37-$102.14M-$0.28N/A
Alkermes$1.48B5.49$241.66M$0.38127.18

Mesoblast has a beta of 2.08, indicating that its share price is 108% more volatile than the broader market. Comparatively, Alkermes has a beta of 0.34, indicating that its share price is 66% less volatile than the broader market.

Summary

Alkermes beats Mesoblast on 13 of the 17 factors compared between the two stocks.

How does Mesoblast compare to Apogee Therapeutics?

Apogee Therapeutics (NASDAQ:APGE) and Mesoblast (NASDAQ:MESO) are both mid-cap healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their valuation, dividends, risk, media sentiment, institutional ownership, earnings, profitability and analyst recommendations.

Apogee Therapeutics has a beta of 0.34, suggesting that its stock price is 66% less volatile than the broader market. Comparatively, Mesoblast has a beta of 2.08, suggesting that its stock price is 108% more volatile than the broader market.

Mesoblast's return on equity of 0.00% beat Apogee Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Apogee TherapeuticsN/A -29.88% -28.08%
Mesoblast N/A N/A N/A

In the previous week, Mesoblast had 3 more articles in the media than Apogee Therapeutics. MarketBeat recorded 8 mentions for Mesoblast and 5 mentions for Apogee Therapeutics. Apogee Therapeutics' average media sentiment score of 1.39 beat Mesoblast's score of 0.01 indicating that Apogee Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Apogee Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Mesoblast
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Neutral

Apogee Therapeutics currently has a consensus target price of $124.43, suggesting a potential downside of 7.66%. Given Apogee Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Apogee Therapeutics is more favorable than Mesoblast.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Apogee Therapeutics
1 Sell rating(s)
15 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.20
Mesoblast
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

79.0% of Apogee Therapeutics shares are held by institutional investors. Comparatively, 1.4% of Mesoblast shares are held by institutional investors. 24.3% of Apogee Therapeutics shares are held by insiders. Comparatively, 18.8% of Mesoblast shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Mesoblast has higher revenue and earnings than Apogee Therapeutics. Mesoblast is trading at a lower price-to-earnings ratio than Apogee Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Apogee TherapeuticsN/AN/A-$255.84M-$4.34N/A
Mesoblast$17.20M128.37-$102.14M-$0.28N/A

Summary

Apogee Therapeutics beats Mesoblast on 8 of the 15 factors compared between the two stocks.

How does Mesoblast compare to ImmunityBio?

Mesoblast (NASDAQ:MESO) and ImmunityBio (NASDAQ:IBRX) are both mid-cap healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their earnings, dividends, analyst recommendations, valuation, profitability, risk, institutional ownership and media sentiment.

Mesoblast has a beta of 2.08, suggesting that its share price is 108% more volatile than the broader market. Comparatively, ImmunityBio has a beta of 0.03, suggesting that its share price is 97% less volatile than the broader market.

Mesoblast has higher earnings, but lower revenue than ImmunityBio. Mesoblast is trading at a lower price-to-earnings ratio than ImmunityBio, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mesoblast$17.20M128.37-$102.14M-$0.28N/A
ImmunityBio$113.29M72.88-$351.40M-$0.97N/A

1.4% of Mesoblast shares are owned by institutional investors. Comparatively, 8.6% of ImmunityBio shares are owned by institutional investors. 18.8% of Mesoblast shares are owned by company insiders. Comparatively, 66.1% of ImmunityBio shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

In the previous week, Mesoblast had 6 more articles in the media than ImmunityBio. MarketBeat recorded 8 mentions for Mesoblast and 2 mentions for ImmunityBio. ImmunityBio's average media sentiment score of 1.13 beat Mesoblast's score of 0.01 indicating that ImmunityBio is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mesoblast
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Neutral
ImmunityBio
1 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Mesoblast has a net margin of 0.00% compared to ImmunityBio's net margin of -598.55%.

Company Net Margins Return on Equity Return on Assets
MesoblastN/A N/A N/A
ImmunityBio -598.55%N/A -51.65%

ImmunityBio has a consensus target price of $14.20, suggesting a potential upside of 82.28%. Given ImmunityBio's stronger consensus rating and higher probable upside, analysts plainly believe ImmunityBio is more favorable than Mesoblast.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mesoblast
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
ImmunityBio
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71

Summary

ImmunityBio beats Mesoblast on 8 of the 15 factors compared between the two stocks.

How does Mesoblast compare to Rhythm Pharmaceuticals?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Mesoblast (NASDAQ:MESO) are both mid-cap healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their valuation, earnings, analyst recommendations, dividends, risk, profitability, institutional ownership and media sentiment.

Rhythm Pharmaceuticals currently has a consensus target price of $142.44, suggesting a potential upside of 29.49%. Given Rhythm Pharmaceuticals' stronger consensus rating and higher probable upside, research analysts plainly believe Rhythm Pharmaceuticals is more favorable than Mesoblast.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.78
Mesoblast
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

In the previous week, Rhythm Pharmaceuticals had 2 more articles in the media than Mesoblast. MarketBeat recorded 10 mentions for Rhythm Pharmaceuticals and 8 mentions for Mesoblast. Rhythm Pharmaceuticals' average media sentiment score of 0.56 beat Mesoblast's score of 0.01 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Mesoblast
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Neutral

Mesoblast has a net margin of 0.00% compared to Rhythm Pharmaceuticals' net margin of -85.59%. Mesoblast's return on equity of 0.00% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-85.59% -159.87% -44.00%
Mesoblast N/A N/A N/A

Mesoblast has lower revenue, but higher earnings than Rhythm Pharmaceuticals. Mesoblast is trading at a lower price-to-earnings ratio than Rhythm Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$189.76M39.73-$196.54M-$3.11N/A
Mesoblast$17.20M128.37-$102.14M-$0.28N/A

1.4% of Mesoblast shares are owned by institutional investors. 5.9% of Rhythm Pharmaceuticals shares are owned by company insiders. Comparatively, 18.8% of Mesoblast shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Rhythm Pharmaceuticals has a beta of 1.92, suggesting that its stock price is 92% more volatile than the broader market. Comparatively, Mesoblast has a beta of 2.08, suggesting that its stock price is 108% more volatile than the broader market.

Summary

Mesoblast beats Rhythm Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does Mesoblast compare to TG Therapeutics?

Mesoblast (NASDAQ:MESO) and TG Therapeutics (NASDAQ:TGTX) are both mid-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their media sentiment, valuation, risk, analyst recommendations, dividends, earnings, profitability and institutional ownership.

In the previous week, TG Therapeutics had 2 more articles in the media than Mesoblast. MarketBeat recorded 10 mentions for TG Therapeutics and 8 mentions for Mesoblast. TG Therapeutics' average media sentiment score of 1.08 beat Mesoblast's score of 0.01 indicating that TG Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mesoblast
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
1 Very Negative mention(s)
Neutral
TG Therapeutics
6 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

TG Therapeutics has a net margin of 55.22% compared to Mesoblast's net margin of 0.00%. TG Therapeutics' return on equity of 73.49% beat Mesoblast's return on equity.

Company Net Margins Return on Equity Return on Assets
MesoblastN/A N/A N/A
TG Therapeutics 55.22%73.49%34.14%

1.4% of Mesoblast shares are held by institutional investors. Comparatively, 58.6% of TG Therapeutics shares are held by institutional investors. 18.8% of Mesoblast shares are held by insiders. Comparatively, 8.9% of TG Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Mesoblast has a beta of 2.08, meaning that its share price is 108% more volatile than the broader market. Comparatively, TG Therapeutics has a beta of 1.62, meaning that its share price is 62% more volatile than the broader market.

TG Therapeutics has a consensus price target of $63.00, suggesting a potential upside of 16.09%. Given TG Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe TG Therapeutics is more favorable than Mesoblast.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mesoblast
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
TG Therapeutics
1 Sell rating(s)
3 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.44

TG Therapeutics has higher revenue and earnings than Mesoblast. Mesoblast is trading at a lower price-to-earnings ratio than TG Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mesoblast$17.20M128.37-$102.14M-$0.28N/A
TG Therapeutics$616.29M13.48$447.18M$2.7419.81

Summary

TG Therapeutics beats Mesoblast on 13 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding MESO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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MESO vs. The Competition

MetricMesoblastBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$2.21B$4.01B$7.37B$12.85B
Dividend YieldN/A3.64%2.53%11.08%
P/E Ratio-60.7111.62272.6024.24
Price / Sales128.371,338.17618.9699.81
Price / CashN/A105.1478.6253.99
Price / Book3.6416.8013.056.20
Net Income-$102.14M-$12.50M$3.47B$348.59M
7 Day Performance8.97%3.29%2.09%0.08%
1 Month Performance5.72%8.23%6.64%3.88%
1 Year Performance7.53%55.05%25.02%16.98%

Mesoblast Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
MESO
Mesoblast
0.3642 of 5 stars
$17.00
-2.5%
N/A+7.5%$2.21B$17.20MN/A80
ALKS
Alkermes
3.1861 of 5 stars
$49.94
+0.2%
$54.56
+9.3%
+62.5%$8.39B$1.48B131.692,050
APGE
Apogee Therapeutics
1.3679 of 5 stars
$134.58
0.0%
$124.43
-7.5%
+252.1%$8.37BN/AN/A91
IBRX
ImmunityBio
2.6518 of 5 stars
$7.67
-3.1%
$14.20
+85.1%
+237.2%$8.14B$113.29MN/A590
RYTM
Rhythm Pharmaceuticals
2.938 of 5 stars
$116.02
+0.5%
$142.44
+22.8%
+6.5%$7.98B$239.92MN/A140

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This page (NASDAQ:MESO) was last updated on 8/23/2026 by MarketBeat.com Staff.
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