Live Earnings Conference Call: Ligand Pharmaceuticals will host a live Q2 2025 earnings call on August 7, 2025 at 8:30AM ET. Follow this link to get details and listen to Ligand Pharmaceuticals' Q2 2025 earnings call when it goes live. Get details. Ligand Pharmaceuticals (LGND) Short Interest Ratio & Short Volume $142.40 +7.25 (+5.36%) Closing price 08/6/2025 04:00 PM EasternExtended Trading$147.74 +5.34 (+3.75%) As of 08/6/2025 07:57 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Ligand Pharmaceuticals Short Interest DataLigand Pharmaceuticals (LGND) has a short interest of 1.23 million shares. This marks a 3.36% increase in short interest from the previous month. The short interest ratio (days to cover) is 8.7, indicating that it would take 8.7 days of the average trading volume of 196,447 shares to cover all short positions.Current Short Interest1,230,000 sharesPrevious Short Interest1,190,000 sharesChange Vs. Previous Month+3.36%Dollar Volume Sold Short$152.89 millionShort Interest Ratio8.7 Days to CoverLast Record DateJuly 15, 2025Outstanding Shares19,290,000 sharesPercentage of Shares Shorted6.38%Today's Trading Volume300,453 sharesAverage Trading Volume196,447 sharesToday's Volume Vs. Average153% Short Selling Ligand Pharmaceuticals? Sign up to receive the latest short interest report for Ligand Pharmaceuticals and its competitors with MarketBeat's FREE newsletter. Email Address Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartLGND Short Interest Over TimeLGND Days to Cover Over TimeLGND Percentage of Float Shorted Over Time Ligand Pharmaceuticals Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 7/15/20251,230,000 shares $152.89 million +3.4%N/A8.7 $124.30 6/30/20251,190,000 shares $135.28 million +3.5%6.6%9.7 $113.68 6/15/20251,150,000 shares $129.38 million -6.5%6.4%9.7 $112.50 5/31/20251,230,000 shares $126.90 million +12.8%6.9%10.2 $103.17 5/15/20251,090,000 shares $112.78 million -10.7%6.1%8.9 $103.47 4/30/20251,220,000 shares $134.03 million +7.0%N/A10.2 $109.86 4/15/20251,140,000 shares $121.75 million +12.9%6.4%10.1 $106.80 3/31/20251,010,000 shares $106.19 million +5.8%5.7%9 $105.14 3/15/2025955,100 shares $101.42 million +22.4%5.4%8.3 $106.19 2/28/2025780,100 shares $95.35 million -7.7%4.4%7.1 $122.23 Get the Latest News and Ratings for LGND and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Ligand Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. 2/15/2025845,000 shares $101.40 million -11.2%4.8%8 $120.00 1/31/2025951,500 shares $110.90 million +4.4%N/A8.2 $116.55 1/15/2025911,400 shares $100.51 million +1.3%N/A7.4 $110.28 12/31/2024900,100 shares $96.45 million +10.7%N/A7.5 $107.15 12/15/2024812,800 shares $95.02 million +3.5%N/A6.9 $116.91 11/30/2024785,700 shares $95.44 million -5.5%N/A7.1 $121.47 11/15/2024831,500 shares $92.89 million -9.5%N/A7.5 $111.71 10/31/2024918,600 shares $97.10 million -8.1%N/A8.5 $105.70 10/15/20241,000,000 shares $104.39 million +0.4%N/A9.5 $104.39 9/30/2024996,100 shares $99.70 million +1.9%N/A8.7 $100.09 9/15/2024977,400 shares $102.40 million -1.8%N/A7.9 $104.77 8/31/2024995,000 shares $105.27 million -6.1%N/A8.1 $105.80 8/15/20241,060,000 shares $109.32 million +10.3%N/A8.3 $103.13 7/31/2024960,700 shares $104.71 million -12.7%N/A6.9 $108.99 7/15/20241,100,000 shares $106.34 million +17.7%N/A7.9 $96.67 6/30/2024934,400 shares $78.73 million -0.2%N/A6.5 $84.26 6/15/2024936,600 shares $74.98 million +32.3%N/A6.6 $80.06 5/31/2024707,700 shares $60.19 million -17.6%N/A4.3 $85.05 5/15/2024858,700 shares $73.65 million +7.9%N/A4.6 $85.77 4/30/2024795,600 shares $55.60 million -3.8%N/A4.3 $69.89 4/15/2024826,600 shares $65.94 million +23.0%5.0%4.9 $79.77 3/31/2024672,100 shares $49.13 million -23.3%4.1%4.1 $73.10 3/15/2024876,300 shares $62.30 million +14.9%5.3%5.8 $71.09 2/29/2024762,600 shares $60.51 million -15.0%4.6%5.3 $79.35 2/15/2024896,600 shares $66.93 million -3.6%5.5%7.3 $74.65 1/31/2024929,800 shares $67.97 million +1.0%5.7%8.1 $73.10 1/15/2024920,700 shares $66.84 million +2.2%6.9%8.2 $72.60 12/31/2023900,800 shares $64.34 million +0.8%5.5%8.2 $71.42 12/15/2023893,600 shares $60.18 million -1.7%5.5%8.1 $67.35 11/30/2023909,100 shares $53.01 million -2.3%5.5%8.8 $58.31$100 Trillion “AI Metal” Found in American Ghost Town (Ad)Jeff Brown recently traveled to a ghost town in the middle of an American desert… To investigate what could be the biggest technology story of this decade. In short, he believes what he's holding in his hand is the key to the $100 trillion AI boom… And only one company here in the U.S. can mine this obscure metal.Click here to get the details on this virtual monopoly. 11/15/2023930,200 shares $52.54 million +6.1%5.7%9.2 $56.48 10/31/2023876,400 shares $45.83 million +3.8%5.4%8.8 $52.29 10/15/2023844,700 shares $46.45 million +2.5%5.2%8.8 $54.99 9/30/2023824,100 shares $49.38 million -0.1%5.1%8.4 $59.92 9/15/2023825,000 shares $51.13 million -6.2%5.1%8.8 $61.98 8/31/2023879,200 shares $57.82 million +4.6%5.4%9.1 $65.77 8/15/2023840,500 shares $56.81 million +4.3%5.2%8.6 $67.59 7/31/2023805,800 shares $53.93 million -3.4%5.0%8.2 $66.93 7/15/2023834,300 shares $56.61 million -1.4%5.1%8.4 $67.85 6/30/2023846,200 shares $61.01 million +4.0%5.2%8.6 $72.10 6/15/2023814,000 shares $64.30 million -1.6%5.0%7.8 $78.99 5/31/2023827,100 shares $57.96 million +1.3%5.1%7.9 $70.08 5/15/2023816,400 shares $63.34 million +0.7%5.0%7.2 $77.59 4/30/2023811,100 shares $61.93 million +5.1%5.1%7 $76.35 4/15/2023771,800 shares $57.38 million -1.0%4.8%6.6 $74.34 3/31/2023779,200 shares $57.32 million -13.5%4.9%6.5 $73.56 3/15/2023900,500 shares $64.48 million +7.5%5.6%7.1 $71.61 2/28/2023838,100 shares $60.46 million +2.5%5.2%5.1 $72.14 2/15/2023817,900 shares $59.69 million +1.5%5.1%4.8 $72.98 1/31/2023806,000 shares $56.18 million +0.1%5.1%4.6 $69.70 1/15/2023805,000 shares $57.38 million +1.5%5.1%4.1 $71.28 12/30/2022792,800 shares $52.96 million -8.4%5.0%4.1 $66.80 12/15/2022865,800 shares $53.81 million +13.0%5.5%4.4 $62.15 11/30/2022766,100 shares $55.85 million -2.3%4.8%4.6 $72.90 11/15/2022784,100 shares $61.99 million +6.6%4.9%5 $79.06 10/31/2022735,400 shares $64.46 million -0.3%4.6%5 $87.65 10/15/2022737,800 shares $66.03 million -6.7%4.6%6 $89.49 9/30/2022790,600 shares $68.08 million -5.1%5.0%6.6 $86.11 9/15/2022833,000 shares $75.08 million +3.1%5.2%7 $90.13 8/31/2022808,200 shares $74.67 million -3.7%5.1%6.6 $92.39 8/15/2022839,000 shares $90.03 million -3.2%5.3%6.8 $107.31 7/31/2022866,700 shares $79.76 million -0.8%5.4%6.5 $92.03 7/15/2022873,600 shares $82.58 million -3.6%5.4%6 $94.53 6/30/2022905,800 shares $80.82 million -0.2%5.6%6 $89.22 6/15/2022907,900 shares $71.80 million -0.6%N/A5.7 $79.08 5/31/2022913,400 shares $81.21 million -10.5%5.7%6.2 $88.91 5/15/20221,020,000 shares $87.68 million -8.9%6.4%6.2 $85.96 4/30/20221,120,000 shares $104.00 million No Change7.0%6.8 $92.86 4/15/20221,120,000 shares $117.89 million -8.9%7.0%6.8 $105.26 3/31/20221,230,000 shares $138.36 million +2.5%7.7%7.2 $112.49 3/15/20221,200,000 shares $125.44 million -2.4%7.5%7.5 $104.53 2/28/20221,230,000 shares $124.50 million No Change7.7%7.7 $101.22 2/15/20221,230,000 shares $152.13 million -10.2%7.8%8.1 $123.68 1/31/20221,370,000 shares $170.74 million -11.0%8.6%9.7 $124.63 1/15/20221,540,000 shares $192.36 million -4.4%9.7%11.3 $124.91 12/31/20211,610,000 shares $248.68 million -4.2%10.1%13.4 $154.46 12/15/20211,680,000 shares $247.80 million +5.0%10.6%13.9 $147.50 11/30/20211,600,000 shares $259.07 million +0.6%10.1%13.5 $161.92 11/15/20211,590,000 shares $260.93 million -4.2%10.0%8 $164.11 10/29/20211,660,000 shares $242.26 million No Change10.5%8 $145.94$100 Trillion “AI Metal” Found in American Ghost Town (Ad)Jeff Brown recently traveled to a ghost town in the middle of an American desert… To investigate what could be the biggest technology story of this decade. In short, he believes what he's holding in his hand is the key to the $100 trillion AI boom… And only one company here in the U.S. can mine this obscure metal.Click here to get the details on this virtual monopoly. 10/15/20211,660,000 shares $216.23 million -4.1%10.5%7.9 $130.26 9/30/20211,730,000 shares $241.02 million -2.8%10.9%8 $139.32 9/15/20211,780,000 shares $241.83 million +10.6%11.2%7.8 $135.86 8/31/20211,610,000 shares $213.00 million -0.6%10.2%7 $132.30 8/13/20211,620,000 shares $173.05 million -1.8%10.2%10.1 $106.82 7/30/20211,650,000 shares $187.29 million -6.3%10.4%11 $113.51 7/15/20211,760,000 shares $203.84 million +0.6%11.1%11.7 $115.82 6/30/20211,750,000 shares $229.58 million +1.7%11.0%11.7 $131.19 6/15/20211,720,000 shares $212.97 million +8.2%10.8%12 $123.82 5/28/20211,590,000 shares $187.14 million -0.6%10.0%9.8 $117.70 5/14/20211,600,000 shares $198.21 million -0.6%10.1%8.5 $123.88 4/30/20211,610,000 shares $234.69 million +2.6%10.1%6.1 $145.77 4/15/20211,570,000 shares $237.12 million +4.7%9.9%2.9 $151.03 3/31/20211,500,000 shares $223.67 million -19.4%9.5%2.6 $149.11 3/15/20211,860,000 shares $306.49 million -15.8%11.8%3 $164.78 2/26/20212,210,000 shares $331.96 million -19.3%14.0%3.6 $150.21 2/12/20212,740,000 shares $493.31 million -54.1%17.9%4.5 $180.04 1/29/20215,970,000 shares $1.14 billion -40.4%38.9%10.3 $191.59 1/15/202110,010,000 shares $1.22 billion +1.0%64.9%21.5 $122.28 12/31/20209,910,000 shares $1.02 billion -0.7%64.2%28.9 $102.63 12/15/20209,980,000 shares $1.02 billion -1.6%64.7%29.5 $101.79 11/30/202010,140,000 shares $871.23 million -4.6%65.7%30.6 $85.92 11/15/202010,630,000 shares $889.84 million -1.0%68.9%32.7 $83.71 10/30/202010,740,000 shares $892.17 million +5.1%69.6%34.8 $83.07 10/15/202010,220,000 shares $1.02 billion +3.9%66.2%34.7 $100.01 9/30/20209,840,000 shares $937.95 million +6.0%63.8%39.7 $95.32 9/15/20209,280,000 shares $890.79 million +3.0%60.1%35 $95.99 8/31/20209,010,000 shares $919.02 million +0.9%58.4%34.6 $102.00 8/14/20208,930,000 shares $1.01 billion +4.6%57.9%31.6 $113.25 LGND Short Interest - Frequently Asked Questions What is Ligand Pharmaceuticals' current short interest? Short interest is the volume of Ligand Pharmaceuticals shares that have been sold short but have not yet been covered or closed out. As of July 15th, investors have sold 1,230,000 shares of LGND short. Learn More on Ligand Pharmaceuticals' current short interest. What is a good short interest ratio for Ligand Pharmaceuticals? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. LGND shares currently have a short interest ratio of 9.0. Learn More on Ligand Pharmaceuticals's short interest ratio. Which institutional investors are shorting Ligand Pharmaceuticals? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Ligand Pharmaceuticals: Walleye Trading LLC, and Walleye Capital LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. Is Ligand Pharmaceuticals' short interest increasing or decreasing? Ligand Pharmaceuticals saw a increase in short interest during the month of July. As of July 15th, there was short interest totaling 1,230,000 shares, an increase of 3.4% from the previous total of 1,190,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. How does Ligand Pharmaceuticals' short interest compare to its competitors? Here is how the short interest of companies in the sector of "medical" compare to Ligand Pharmaceuticals: ADMA Biologics Inc (6.06%), ANI Pharmaceuticals, Inc. (9.83%), Exelixis, Inc. (6.92%), Exact Sciences Corporation (3.96%), Halozyme Therapeutics, Inc. (7.88%), Ionis Pharmaceuticals, Inc. (8.30%), Madrigal Pharmaceuticals, Inc. (17.07%), Repligen Corporation (6.40%), Alkermes plc (7.61%), Amicus Therapeutics, Inc. (7.05%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: Coinbase Global, Inc. ($5.11 billion), Charter Communications, Inc. ($4.76 billion), Reddit Inc. ($2.84 billion), SoFi Technologies, Inc. ($2.79 billion), Seagate Technology Holdings PLC ($2.79 billion), Live Nation Entertainment, Inc. ($2.67 billion), Rocket Lab Corporation ($2.49 billion), AST SpaceMobile, Inc. ($2.12 billion), Moderna, Inc. ($2.09 billion), and Omnicom Group Inc. ($2.04 billion). View all of the most shorted stocks. What does it mean to sell short Ligand Pharmaceuticals stock? Short selling LGND is an investing strategy that aims to generate trading profit from Ligand Pharmaceuticals as its price is falling. LGND shares are trading up $7.25 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Ligand Pharmaceuticals? A short squeeze for Ligand Pharmaceuticals occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of LGND, which in turn drives the price of the stock up even further. How often is Ligand Pharmaceuticals' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including LGND, twice per month. The most recent reporting period available is July, 15 2025. More Short Interest Resources from MarketBeat Related Companies ADMA Biologics Short Interest Data ANI Pharmaceuticals Short Interest Data Exelixis Short Interest Data Exact Sciences Short Interest Data Halozyme Therapeutics Short Interest Data Ionis Pharmaceuticals Short Interest Data Madrigal Pharmaceuticals Short Interest Data Repligen Short Interest Data Alkermes Short Interest Data Amicus Therapeutics Short Interest Data Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:LGND) was last updated on 8/7/2025 by MarketBeat.com Staff From Our PartnersMan Who Called Nvidia at $1.10 Says Buy This Now...In 2004, one man called Nvidia before just about anyone knew it existed. 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