Lyra Therapeutics (LYRA) Institutional Ownership $7.10 -0.19 (-2.61%) Closing price 08/14/2025 04:00 PM EasternExtended Trading$7.08 -0.02 (-0.35%) As of 08/14/2025 04:41 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Lyra Therapeutics (NASDAQ:LYRA)CurrentInstitutional OwnershipPercentage95.62%Number ofInstitutional Buyers(last 12 months)7TotalInstitutional Inflows(last 12 months)$14.31MNumber ofInstitutional Sellers(last 12 months)5TotalInstitutional Outflows(last 12 months)$21.27M Get LYRA Insider Trade Alerts Want to know when executives and insiders are buying or selling Lyra Therapeutics stock? 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Email Address Skip Chart & View Institutional Buying and Selling Data LYRA Institutional Buying and Selling by Quarter Lyra Therapeutics Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails8/15/2025Bank of America Corp DE28,542$256K0.0%+33.7%1.740% 8/8/2025 Geode Capital Management LLC10,986$98K0.0%-98.9%0.687% 6/27/2025Goldman Sachs Group Inc.370,194$47K0.0%-33.4%27.834% 5/16/2025Goldman Sachs Group Inc.370,194$47K0.0%-33.4%0.559% 2/17/2025Two Sigma Investments LP209,997$43K0.0%-25.7%0.321% 2/17/2025Two Sigma Advisers LP385,500$80K0.0%-16.3%0.589% 2/17/2025BNP Paribas Financial Markets244,920$51K0.0%N/A0.374% 2/14/2025Samsara BioCapital LLC1,965,689$406K0.1%-29.3%3.003% 2/14/2025 Northern Trust Corp286,310$59K0.0%+56.2%0.437% 2/13/2025ADAR1 Capital Management LLC533,200$110K0.0%N/A0.815% Get the Latest News and Ratings for LYRA and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Lyra Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 2/12/2025 Geode Capital Management LLC885,966$183K0.0%+15.3%1.353% 2/12/2025 JPMorgan Chase & Co.156,442$32K0.0%+161.8%0.239% 11/15/2024State Street Corp488,720$126K0.0%+88.1%0.747% 8/6/2024 Acadian Asset Management LLC985,631$271K0.0%N/A1.617% 7/12/2024Rosalind Advisors Inc.1,034,773$286K0.2%-9.6%1.697% 5/17/2024Ikarian Capital LLC1,056,829$6.57M0.7%-15.7%1.733% 5/10/2024 Vanguard Group Inc.1,481,481$9.22M0.0%+38.3%2.430% 4/25/2024Rosalind Advisors Inc.1,144,524$7.12M6.7%-39.4%1.916% 2/15/2024Parkman Healthcare Partners LLC754,885$3.96M0.6%+20.8%1.436% 2/14/2024Vestal Point Capital LP3,000,000$15.72M1.7%N/A5.708% 2/13/2024Armistice Capital LLC1,088,000$5.70M0.1%-29.8%2.070% 2/7/2024 Jump Financial LLC16,737$88K0.0%N/A0.032% 1/25/2024 Heritage Wealth Management Inc. Texas10,000$52K0.0%N/A0.019% 12/6/2023 Citigroup Inc.67,677$265K0.0%N/A0.129% 11/15/2023Armistice Capital LLC1,550,000$6.06M0.1%-61.4%2.949% 11/14/2023 Prescott Group Capital Management L.L.C.30,000$117K0.0%N/A0.057% 10/24/2023 Bank of New York Mellon Corp18,621$73K0.0%N/A0.038% 8/24/2023Perceptive Advisors LLC12,757,562$52.43M1.5%+39.5%25.747% 8/14/2023Samsara BioCapital LLC2,780,261$11.43M2.0%+56.4%8.733% 8/14/2023 Pura Vida Investments LLC1,413,242$5.72M0.8%-29.2%4.439% 8/10/2023 Letko Brosseau & Associates Inc.31,900$131K0.0%N/A0.100% 2/15/2023Nantahala Capital Management LLC2,220,830$6.97M0.5%-1.1%6.977% 2/14/2023 Pura Vida Investments LLC2,157,298$6.77M0.3%-14.1%6.778% 11/15/2022 Pura Vida Investments LLC2,510,302$12.58M0.7%-2.6%7.888% 11/14/2022Boothbay Fund Management LLC34,721$174K0.0%-9.5%0.109% 11/10/2022Nantahala Capital Management LLC2,245,830$11.25M0.7%-5.2%17.262% 8/16/2022 Pura Vida Investments LLC2,576,196$14.56M0.8%+394.9%19.802% 8/16/2022CVI Holdings LLC60,822$344K0.0%N/A0.468% 8/15/2022Nantahala Capital Management LLC2,369,668$13.39M0.7%N/A18.214% 8/12/2022 Ensign Peak Advisors Inc56,229$318K0.0%+43.6%0.432% He Called Nvidia at $1.10. 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Now, the man who called Nvidia at $1.10 reveals AI’s Next Magnificent Seven… including one stock he says could become America’s next trillion-dollar giant.See his full breakdown of the seven stocks to own now8/12/2022Ikarian Capital LLC347,338$1.96M0.4%-17.8%2.670% 5/16/2022Clearline Capital LP119,924$482K0.1%+84.9%0.922% 2/14/2022Clearline Capital LP64,862$283K0.0%N/A0.499% 2/14/2022Soleus Capital Management L.P.10,000$44K0.0%-95.4%0.077% 2/11/2022Pentwater Capital Management LP71,313$311K0.0%+122.8%0.548% 11/16/2021Two Sigma Advisers LP58,000$529K0.0%+31.8%0.446% 11/15/2021 Pura Vida Investments LLC533,417$4.87M0.1%-1.7%4.103% 11/15/2021 Marshall Wace LLP12,457$114K0.0%-35.5%0.096% 11/9/2021BlackRock Inc.17,818$163K0.0%-11.4%0.137% 11/4/2021 Close Asset Management Ltd7,000$64K0.0%N/A0.054% 8/25/2021 Marshall Wace LLP19,321$155K0.0%-58.8%0.149% 8/18/2021Ikarian Capital LLC624,684$5.02M0.4%-20.0%4.805% 8/17/2021 Walleye Capital LLC19,093$153K0.0%N/A0.147% 8/17/2021Millennium Management LLC155,135$1.25M0.0%N/A1.193% 8/17/2021Bridgeway Capital Management LLC41,900$336K0.0%-14.5%0.322% 8/16/2021Tibra Equities Europe Ltd40,000$321K0.1%N/A0.308% 8/16/2021 Marshall Wace LLP19,321$155K0.0%-58.8%0.149% 8/13/2021 Geode Capital Management LLC36,102$289K0.0%-60.0%0.278% 8/13/2021 Vanguard Group Inc.220,029$1.77M0.0%+3.8%1.692% 8/12/2021 Trexquant Investment LP11,610$93K0.0%N/A0.089% 8/12/2021Ergoteles LLC31,000$249K0.0%N/A0.238% 8/11/2021 Deutsche Bank AG76,441$614K0.0%-5.4%0.588% 8/11/2021Susquehanna International Group LLP21,529$173K0.0%N/A0.166% 8/2/2021 Advisor Group Holdings Inc.4,434$36K0.0%-89.6%0.034% 5/18/2021Morgan Stanley107,217$1.24M0.0%+655.0%0.825% 5/17/2021Nuveen Asset Management LLC17,913$208K0.0%N/A0.138% (Data available from 1/1/2016 forward) LYRA Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of LYRA shares? During the previous two years, 24 institutional investors and hedge funds held shares of Lyra Therapeutics. The most heavily invested institutionals were Perceptive Advisors LLC ($52.43M), Vestal Point Capital LP ($15.72M), Vanguard Group Inc. ($9.22M), Ikarian Capital LLC ($6.57M), Armistice Capital LLC ($5.70M), Parkman Healthcare Partners LLC ($3.96M), and Samsara BioCapital LLC ($406K).Learn more on Lyra Therapeutics' institutional investors. What percentage of Lyra Therapeutics' stock is owned by institutional investors? 95.62% of Lyra Therapeutics' stock is owned by institutional investors. Learn more on LYRA's institutional investor holdings. Which institutional investors have been buying Lyra Therapeutics' stock? Of the 17 institutional investors that purchased Lyra Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Perceptive Advisors LLC ($3.61M), Vestal Point Capital LP ($3M), Acadian Asset Management LLC ($985.63K), ADAR1 Capital Management LLC ($533.20K), Vanguard Group Inc. ($410.02K), BNP Paribas Financial Markets ($244.92K), and State Street Corp ($228.90K). How much institutional buying is happening at Lyra Therapeutics? Institutional investors have bought a total of 1,331,495 shares in the last 24 months. This purchase volume represents approximately $14.31M in transactions. Which of Lyra Therapeutics' major shareholders have been selling company stock? The following institutional investors have sold Lyra Therapeutics stock in the last 24 months: Geode Capital Management LLC ($1.01M), Samsara BioCapital LLC ($814.57K), Goldman Sachs Group Inc. ($370.63K), Two Sigma Advisers LP ($74.80K), and Two Sigma Investments LP ($72.55K). How much institutional selling is happening at Lyra Therapeutics? Institutional investors have sold a total of 2,337,568 shares in the last 24 months. This volume of shares sold represents approximately $21.27M in transactions. Related Companies NEPH Institutional Ownership MODD Institutional Ownership NMTC Institutional Ownership POCI Institutional Ownership CLGN Institutional Ownership ECOR Institutional Ownership COCH Institutional Ownership FEMY Institutional Ownership VVOS Institutional Ownership DRIO Institutional Ownership This page (NASDAQ:LYRA) was last updated on 8/15/2025 by MarketBeat.com Staff From Our PartnersTrump’s national nightmare is herePorter Stansberry and Jeff Brown say a new U.S. national emergency is already underway — and it could trigger ...Porter & Company | SponsoredAlex’s “Next Magnificent Seven” stocksThe original “Magnificent Seven” turned $7K into $1.18 million. 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