Free Trial
→ If You Keep Cash In A U.S. Bank Account… Read This NOW (From Banyan Hill Publishing) (Ad)tc pixel Free LYRA Stock Alerts

Lyra Therapeutics (LYRA) Institutional Ownership

Lyra Therapeutics logo
$6.36 -0.14 (-2.15%)
Closing price 09/25/2025 04:00 PM Eastern
Extended Trading
$6.30 -0.06 (-0.86%)
As of 09/25/2025 07:19 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.
Compare

Institutional Ownership Changes (13F Filings) for Lyra Therapeutics (NASDAQ:LYRA)

Current
Institutional Ownership
Percentage
95.62%
Number of
Institutional Buyers
(last 12 months)
7
Total
Institutional Inflows
(last 12 months)
$14.31M
Number of
Institutional Sellers
(last 12 months)
6
Total
Institutional Outflows
(last 12 months)
$133.29M
Get LYRA Insider Trade Alerts

Want to know when executives and insiders are buying or selling Lyra Therapeutics stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily.

Subscribe Now
By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy.
Skip Chart & View Institutional Buying and Selling Data

LYRA Institutional Buying and Selling by Quarter

Lyra Therapeutics Major Shareholders & Ownership History

Export to Excel
Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
8/15/2025 Perceptive Advisors LLC255,150$2.29M0.2%-98.0%15.558%
8/15/2025 Bank of America Corp DE28,542$256K0.0%+33.7%1.740%
8/8/2025 Geode Capital Management LLC10,986$98K0.0%-98.9%0.687%
6/27/2025 Goldman Sachs Group Inc.370,194$47K0.0%-33.4%27.834%
5/16/2025Goldman Sachs Group Inc.370,194$47K0.0%-33.4%0.559%
2/17/2025Two Sigma Investments LP209,997$43K0.0%-25.7%0.321%
2/17/2025Two Sigma Advisers LP385,500$80K0.0%-16.3%0.589%
2/17/2025BNP Paribas Financial Markets244,920$51K0.0%N/A0.374%
2/14/2025Samsara BioCapital LLC1,965,689$406K0.1%-29.3%3.003%
2/14/2025Northern Trust Corp286,310$59K0.0%+56.2%0.437%
2/13/2025ADAR1 Capital Management LLC533,200$110K0.0%N/A0.815%
2/12/2025Geode Capital Management LLC885,966$183K0.0%+15.3%1.353%
2/12/2025JPMorgan Chase & Co.156,442$32K0.0%+161.8%0.239%
11/15/2024State Street Corp488,720$126K0.0%+88.1%0.747%
8/6/2024Acadian Asset Management LLC985,631$271K0.0%N/A1.617%
7/12/2024Rosalind Advisors Inc.1,034,773$286K0.2%-9.6%1.697%
5/17/2024Ikarian Capital LLC1,056,829$6.57M0.7%-15.7%1.733%
5/10/2024Vanguard Group Inc.1,481,481$9.22M0.0%+38.3%2.430%
4/25/2024Rosalind Advisors Inc.1,144,524$7.12M6.7%-39.4%1.916%
2/15/2024Parkman Healthcare Partners LLC754,885$3.96M0.6%+20.8%1.436%
2/14/2024Vestal Point Capital LP3,000,000$15.72M1.7%N/A5.708%
2/13/2024Armistice Capital LLC1,088,000$5.70M0.1%-29.8%2.070%
2/7/2024Jump Financial LLC16,737$88K0.0%N/A0.032%
1/25/2024Heritage Wealth Management Inc. Texas10,000$52K0.0%N/A0.019%
12/6/2023Citigroup Inc.67,677$265K0.0%N/A0.129%
11/15/2023Armistice Capital LLC1,550,000$6.06M0.1%-61.4%2.949%
11/14/2023Prescott Group Capital Management L.L.C.30,000$117K0.0%N/A0.057%
10/24/2023Bank of New York Mellon Corp18,621$73K0.0%N/A0.038%
8/24/2023Perceptive Advisors LLC12,757,562$52.43M1.5%+39.5%25.747%
8/14/2023Samsara BioCapital LLC2,780,261$11.43M2.0%+56.4%8.733%
8/14/2023Pura Vida Investments LLC1,413,242$5.72M0.8%-29.2%4.439%
8/10/2023Letko Brosseau & Associates Inc.31,900$131K0.0%N/A0.100%
2/15/2023Nantahala Capital Management LLC2,220,830$6.97M0.5%-1.1%6.977%
2/14/2023Pura Vida Investments LLC2,157,298$6.77M0.3%-14.1%6.778%
11/15/2022Pura Vida Investments LLC2,510,302$12.58M0.7%-2.6%7.888%
11/14/2022Boothbay Fund Management LLC34,721$174K0.0%-9.5%0.109%
11/10/2022Nantahala Capital Management LLC2,245,830$11.25M0.7%-5.2%17.262%
8/16/2022Pura Vida Investments LLC2,576,196$14.56M0.8%+394.9%19.802%
8/16/2022CVI Holdings LLC60,822$344K0.0%N/A0.468%
8/15/2022Nantahala Capital Management LLC2,369,668$13.39M0.7%N/A18.214%
8/12/2022Ensign Peak Advisors Inc56,229$318K0.0%+43.6%0.432%
8/12/2022Ikarian Capital LLC347,338$1.96M0.4%-17.8%2.670%
5/16/2022Clearline Capital LP119,924$482K0.1%+84.9%0.922%
2/14/2022Clearline Capital LP64,862$283K0.0%N/A0.499%
2/14/2022Soleus Capital Management L.P.10,000$44K0.0%-95.4%0.077%
2/11/2022Pentwater Capital Management LP71,313$311K0.0%+122.8%0.548%
11/16/2021Two Sigma Advisers LP58,000$529K0.0%+31.8%0.446%
11/15/2021Pura Vida Investments LLC533,417$4.87M0.1%-1.7%4.103%
11/15/2021Marshall Wace LLP12,457$114K0.0%-35.5%0.096%
11/9/2021BlackRock Inc.17,818$163K0.0%-11.4%0.137%
11/4/2021Close Asset Management Ltd7,000$64K0.0%N/A0.054%
8/25/2021Marshall Wace LLP19,321$155K0.0%-58.8%0.149%
8/18/2021Ikarian Capital LLC624,684$5.02M0.4%-20.0%4.805%
8/17/2021Walleye Capital LLC19,093$153K0.0%N/A0.147%
8/17/2021Millennium Management LLC155,135$1.25M0.0%N/A1.193%
8/17/2021Bridgeway Capital Management LLC41,900$336K0.0%-14.5%0.322%
8/16/2021Tibra Equities Europe Ltd40,000$321K0.1%N/A0.308%
8/16/2021Marshall Wace LLP19,321$155K0.0%-58.8%0.149%
8/13/2021Geode Capital Management LLC36,102$289K0.0%-60.0%0.278%
8/13/2021Vanguard Group Inc.220,029$1.77M0.0%+3.8%1.692%
8/12/2021Trexquant Investment LP11,610$93K0.0%N/A0.089%
8/12/2021Ergoteles LLC31,000$249K0.0%N/A0.238%
8/11/2021Deutsche Bank AG76,441$614K0.0%-5.4%0.588%
8/11/2021Susquehanna International Group LLP21,529$173K0.0%N/A0.166%
8/2/2021Advisor Group Holdings Inc.4,434$36K0.0%-89.6%0.034%
(Data available from 1/1/2016 forward)

LYRA Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of LYRA shares?

During the previous two years, 24 institutional investors and hedge funds held shares of Lyra Therapeutics. The most heavily invested institutionals were Vestal Point Capital LP ($15.72M), Vanguard Group Inc. ($9.22M), Ikarian Capital LLC ($6.57M), Armistice Capital LLC ($5.70M), Parkman Healthcare Partners LLC ($3.96M), Perceptive Advisors LLC ($2.29M), and Samsara BioCapital LLC ($406K).Learn more on Lyra Therapeutics' institutional investors.

What percentage of Lyra Therapeutics' stock is owned by institutional investors?

95.62% of Lyra Therapeutics' stock is owned by institutional investors. Learn more on LYRA's institutional investor holdings.

Which institutional investors have been buying Lyra Therapeutics' stock?

Of the 16 institutional investors that purchased Lyra Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Vestal Point Capital LP ($3M), Acadian Asset Management LLC ($985.63K), ADAR1 Capital Management LLC ($533.20K), Vanguard Group Inc. ($410.02K), BNP Paribas Financial Markets ($244.92K), State Street Corp ($228.90K), and Parkman Healthcare Partners LLC ($129.83K).

How much institutional buying is happening at Lyra Therapeutics?

Institutional investors have bought a total of 1,331,495 shares in the last 24 months. This purchase volume represents approximately $14.31M in transactions.

Which of Lyra Therapeutics' major shareholders have been selling company stock?

The following institutional investors have sold Lyra Therapeutics stock in the last 24 months: Perceptive Advisors LLC ($12.50M), Geode Capital Management LLC ($1.01M), Samsara BioCapital LLC ($814.57K), Goldman Sachs Group Inc. ($370.63K), Two Sigma Advisers LP ($74.80K), and Two Sigma Investments LP ($72.55K).

How much institutional selling is happening at Lyra Therapeutics?

Institutional investors have sold a total of 14,839,980 shares in the last 24 months. This volume of shares sold represents approximately $133.29M in transactions.


Related Companies

This page (NASDAQ:LYRA) was last updated on 9/26/2025 by MarketBeat.com Staff
From Our Partners
Another gold high? Here’s the move Wall Street is missing …
Gold has surged past $3,600 an ounce, up 45% in the last year, but Weiss Ratings analyst Sean Brodrick says th...
Weiss Ratings | Sponsoredtc pixel
Stunning new initiative unfolding in the White House?
what I just learned about what’s unfolding in the White House is truly stunning… And you need to see it for...
Paradigm Press | Sponsoredtc pixel
Strange crypto pattern discovered by 40-person research team
Something unusual is happening inside a 40-person crypto research firm. They're helping 8,000+ ordinary peo...
Crypto Swap Profits | Sponsoredtc pixel
Market Panic: Trump Just Dropped a Bomb on Your Stocks
tock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tarif...
American Alternative | Sponsoredtc pixel
If You Keep Cash In A U.S. Bank Account… Read This NOW
The Treasury Department just issued a stunning warning: U.S. banks could lose up to $6.6 trillion of custom...
Banyan Hill Publishing | Sponsoredtc pixel
New Buy Alert: Should you put $1,000 into Oracle (ORCL) now?
Barron's is calling this Oracle's "Nvidia Moment..." While the Wall Street Journal is simply calling Oracle...
Chaikin Analytics | Sponsoredtc pixel
Why More Investors Are Using Family Trusts to Protect Their Wealth
For many investors, a family trust can be an essential tool for protecting assets, avoiding probate, and ensur...
SmartAsset | Sponsoredtc pixel
6-Figure Target for BTC by 2025
Crypto ETF records broken – here's what’s next The biggest names in finance have built the infrastructure f...
Crypto 101 Media | Sponsoredtc pixel