Lyra Therapeutics (LYRA) Institutional Ownership $7.95 -0.19 (-2.33%) Closing price 04:00 PM EasternExtended Trading$8.04 +0.09 (+1.07%) As of 05:54 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Lyra Therapeutics (NASDAQ:LYRA)CurrentInstitutional OwnershipPercentage95.62%Number ofInstitutional Buyers(last 12 months)7TotalInstitutional Inflows(last 12 months)$27.88MNumber ofInstitutional Sellers(last 12 months)4TotalInstitutional Outflows(last 12 months)$12.27M Get LYRA Insider Trade Alerts Want to know when executives and insiders are buying or selling Lyra Therapeutics stock? 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Email Address Skip Chart & View Institutional Buying and Selling Data LYRA Institutional Buying and Selling by Quarter Lyra Therapeutics Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails6/27/2025Goldman Sachs Group Inc.370,194$47K0.0%-33.4%27.834% 5/16/2025Goldman Sachs Group Inc.370,194$47K0.0%-33.4%0.559% 2/17/2025Two Sigma Investments LP209,997$43K0.0%-25.7%0.321% 2/17/2025Two Sigma Advisers LP385,500$80K0.0%-16.3%0.589% 2/17/2025BNP Paribas Financial Markets244,920$51K0.0%N/A0.374% 2/14/2025Samsara BioCapital LLC1,965,689$406K0.1%-29.3%3.003% 2/14/2025Northern Trust Corp286,310$59K0.0%+56.2%0.437% 2/13/2025ADAR1 Capital Management LLC533,200$110K0.0%N/A0.815% 2/12/2025Geode Capital Management LLC885,966$183K0.0%+15.3%1.353% 2/12/2025JPMorgan Chase & Co.156,442$32K0.0%+161.8%0.239% Get the Latest News and Ratings for LYRA and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Lyra Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 11/15/2024State Street Corp488,720$126K0.0%+88.1%0.747% 8/6/2024Acadian Asset Management LLC985,631$271K0.0%N/A1.617% 7/12/2024Rosalind Advisors Inc.1,034,773$286K0.2%-9.6%1.697% 5/17/2024Ikarian Capital LLC1,056,829$6.57M0.7%-15.7%1.733% 5/10/2024Vanguard Group Inc.1,481,481$9.22M0.0%+38.3%2.430% 4/25/2024Rosalind Advisors Inc.1,144,524$7.12M6.7%-39.4%1.916% 2/15/2024Parkman Healthcare Partners LLC754,885$3.96M0.6%+20.8%1.436% 2/14/2024Vestal Point Capital LP3,000,000$15.72M1.7%N/A5.708% 2/13/2024Armistice Capital LLC1,088,000$5.70M0.1%-29.8%2.070% 2/7/2024Jump Financial LLC16,737$88K0.0%N/A0.032% 1/25/2024Heritage Wealth Management Inc. Texas10,000$52K0.0%N/A0.019% 12/6/2023Citigroup Inc.67,677$265K0.0%N/A0.129% 11/15/2023Armistice Capital LLC1,550,000$6.06M0.1%-61.4%2.949% 11/14/2023Prescott Group Capital Management L.L.C.30,000$117K0.0%N/A0.057% 10/24/2023Bank of New York Mellon Corp18,621$73K0.0%N/A0.038% 8/24/2023Perceptive Advisors LLC12,757,562$52.43M1.5%+39.5%25.747% 8/14/2023Samsara BioCapital LLC2,780,261$11.43M2.0%+56.4%8.733% 8/14/2023Pura Vida Investments LLC1,413,242$5.72M0.8%-29.2%4.439% 8/10/2023Letko Brosseau & Associates Inc.31,900$131K0.0%N/A0.100% 2/15/2023Nantahala Capital Management LLC2,220,830$6.97M0.5%-1.1%6.977% 2/14/2023Pura Vida Investments LLC2,157,298$6.77M0.3%-14.1%6.778% 11/15/2022Pura Vida Investments LLC2,510,302$12.58M0.7%-2.6%7.888% 11/14/2022Boothbay Fund Management LLC34,721$174K0.0%-9.5%0.109% 11/10/2022Nantahala Capital Management LLC2,245,830$11.25M0.7%-5.2%17.262% 8/16/2022Pura Vida Investments LLC2,576,196$14.56M0.8%+394.9%19.802% 8/16/2022CVI Holdings LLC60,822$344K0.0%N/A0.468% 8/15/2022Nantahala Capital Management LLC2,369,668$13.39M0.7%N/A18.214% 8/12/2022Ensign Peak Advisors Inc56,229$318K0.0%+43.6%0.432% 8/12/2022Ikarian Capital LLC347,338$1.96M0.4%-17.8%2.670% 5/16/2022Clearline Capital LP119,924$482K0.1%+84.9%0.922% The End of Elon Musk…? 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According to his research, if you listen to the media and miss out on Elon's newest breakthrough, it's going to cost you the fortune of a lifetime.Click here to see why the "End of Elon" crowd is about to be wrong again.2/14/2022Clearline Capital LP64,862$283K0.0%N/A0.499% 2/14/2022Soleus Capital Management L.P.10,000$44K0.0%-95.4%0.077% 2/11/2022Pentwater Capital Management LP71,313$311K0.0%+122.8%0.548% 11/16/2021Two Sigma Advisers LP58,000$529K0.0%+31.8%0.446% 11/15/2021Pura Vida Investments LLC533,417$4.87M0.1%-1.7%4.103% 11/15/2021Marshall Wace LLP12,457$114K0.0%-35.5%0.096% 11/9/2021BlackRock Inc.17,818$163K0.0%-11.4%0.137% 11/4/2021Close Asset Management Ltd7,000$64K0.0%N/A0.054% 8/25/2021Marshall Wace LLP19,321$155K0.0%-58.8%0.149% 8/18/2021Ikarian Capital LLC624,684$5.02M0.4%-20.0%4.805% 8/17/2021Walleye Capital LLC19,093$153K0.0%N/A0.147% 8/17/2021Millennium Management LLC155,135$1.25M0.0%N/A1.193% 8/17/2021Bridgeway Capital Management LLC41,900$336K0.0%-14.5%0.322% 8/16/2021Tibra Equities Europe Ltd40,000$321K0.1%N/A0.308% 8/16/2021Marshall Wace LLP19,321$155K0.0%-58.8%0.149% 8/13/2021Geode Capital Management LLC36,102$289K0.0%-60.0%0.278% 8/13/2021Vanguard Group Inc.220,029$1.77M0.0%+3.8%1.692% 8/12/2021Trexquant Investment LP11,610$93K0.0%N/A0.089% 8/12/2021Ergoteles LLC31,000$249K0.0%N/A0.238% 8/11/2021Deutsche Bank AG76,441$614K0.0%-5.4%0.588% 8/11/2021Susquehanna International Group LLP21,529$173K0.0%N/A0.166% 8/2/2021Advisor Group Holdings Inc.4,434$36K0.0%-89.6%0.034% 5/18/2021Morgan Stanley107,217$1.24M0.0%+655.0%0.825% 5/17/2021Nuveen Asset Management LLC17,913$208K0.0%N/A0.138% 5/13/2021Bank of New York Mellon Corp15,036$174K0.0%-22.7%0.116% 5/12/2021Northern Trust Corp64,451$746K0.0%-5.2%0.497% 5/12/2021Geode Capital Management LLC90,281$1.05M0.0%+31.8%0.696% (Data available from 1/1/2016 forward) LYRA Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of LYRA shares? During the previous two years, 25 institutional investors and hedge funds held shares of Lyra Therapeutics. The most heavily invested institutionals were Perceptive Advisors LLC ($52.43M), Vestal Point Capital LP ($15.72M), Vanguard Group Inc. ($9.22M), Ikarian Capital LLC ($6.57M), Pura Vida Investments LLC ($5.72M), Armistice Capital LLC ($5.70M), and Parkman Healthcare Partners LLC ($3.96M).Learn more on Lyra Therapeutics' institutional investors. What percentage of Lyra Therapeutics' stock is owned by institutional investors? 95.62% of Lyra Therapeutics' stock is owned by institutional investors. Learn more on LYRA's institutional investor holdings. Which institutional investors have been buying Lyra Therapeutics' stock? Of the 18 institutional investors that purchased Lyra Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Perceptive Advisors LLC ($3.61M), Vestal Point Capital LP ($3M), Samsara BioCapital LLC ($1.00M), Acadian Asset Management LLC ($985.63K), ADAR1 Capital Management LLC ($533.20K), Vanguard Group Inc. ($410.02K), and BNP Paribas Financial Markets ($244.92K). How much institutional buying is happening at Lyra Therapeutics? Institutional investors have bought a total of 2,309,936 shares in the last 24 months. This purchase volume represents approximately $27.88M in transactions. Which of Lyra Therapeutics' major shareholders have been selling company stock? The following institutional investors have sold Lyra Therapeutics stock in the last 24 months: Samsara BioCapital LLC ($814.57K), Goldman Sachs Group Inc. ($370.63K), Two Sigma Advisers LP ($74.80K), and Two Sigma Investments LP ($72.55K). How much institutional selling is happening at Lyra Therapeutics? Institutional investors have sold a total of 1,332,550 shares in the last 24 months. This volume of shares sold represents approximately $12.27M in transactions. Related Companies PYPD Institutional Ownership MODD Institutional Ownership NEPH Institutional Ownership POCI Institutional Ownership COCH Institutional Ownership VVOS Institutional Ownership DRIO Institutional Ownership FEMY Institutional Ownership CLGN Institutional Ownership ALUR Institutional Ownership This page (NASDAQ:LYRA) was last updated on 7/25/2025 by MarketBeat.com Staff From Our PartnersINVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting OffRight now, we’re witnessing a monumental shift in the world.Traders Agency | SponsoredGoogle did what!?!?A new technology has sparked a modern-day gold rush in Silicon Valley. OpenAI’s Sam Altman invested $375M. 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