Positive News SentimentPositive NewsNASDAQ:MCRB Seres Therapeutics (MCRB) Stock Price, News & Analysis $20.59 -0.45 (-2.14%) Closing price 10/3/2025 04:00 PM EasternExtended Trading$20.30 -0.29 (-1.41%) As of 10/3/2025 06:36 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock About Seres Therapeutics Stock (NASDAQ:MCRB) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Seres Therapeutics alerts:Sign Up Key Stats Today's Range$19.14▼$22.0050-Day Range$12.15▼$22.8552-Week Range$6.53▼$24.67Volume264,845 shsAverage Volume268,113 shsMarket Capitalization$180.16 millionP/E RatioN/ADividend YieldN/APrice Target$14.33Consensus RatingReduce Company Overview Seres Therapeutics is a clinical‐stage microbiome therapeutics company focused on harnessing the power of the human microbiome to treat serious diseases. Headquartered in Cambridge, Massachusetts, Seres applies proprietary microbiome science and manufacturing capabilities to develop a pipeline of living microbial therapies designed to restore healthy gut function. The company’s approach leverages understanding of microbial ecology and human biology to address conditions where the native microbiome is disrupted. Among its lead candidates is SER-109, an investigational oral microbiome therapeutic for reducing recurrence of Clostridioides difficile infection. Seres is also advancing SER-287 in ulcerative colitis, SER-401 in combination with immunotherapy for certain cancers, and other preclinical programs targeting metabolic and inflammatory diseases. The company collaborates with strategic partners, including Nestlé Health Science, to support development, manufacturing scale-up and global research efforts. Founded in 2010, Seres went public in 2015 to further accelerate its clinical pipeline. The management team comprises experienced biotech executives, clinicians and scientists with expertise in microbiome research and product development. Seres continues to conduct multi‐center clinical trials across North America and Europe, seeking to bring first‐in‐class microbiome therapies to patients with limited treatment options.AI Generated. May Contain Errors. Read More Seres Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks49th Percentile Overall ScoreMCRB MarketRank™: Seres Therapeutics scored higher than 49% of companies evaluated by MarketBeat, and ranked 592nd out of 941 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion1.2 / 5Analyst RatingReduce Consensus RatingSeres Therapeutics has received a consensus rating of Reduce. The company's average rating score is 1.60, and is based on 1 buy rating, 1 hold rating, and 3 sell ratings.Downside RiskSeres Therapeutics has a consensus price target of $14.33, representing about 30.4% downside from its current price of $20.59.Amount of Analyst CoverageSeres Therapeutics has only been the subject of 2 research reports in the past 90 days.Read more about Seres Therapeutics' stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Seres Therapeutics are expected to decrease in the coming year, from ($0.38) to ($0.56) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Seres Therapeutics is -4.48, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Seres Therapeutics is -4.48, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioSeres Therapeutics has a P/B Ratio of 12.79. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Seres Therapeutics' valuation and earnings. Short Interest3.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted14.47% of the float of Seres Therapeutics has been sold short.Short Interest Ratio / Days to CoverSeres Therapeutics has a short interest ratio ("days to cover") of 5.2.Change versus previous monthShort interest in Seres Therapeutics has recently decreased by 7.30%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldSeres Therapeutics does not currently pay a dividend.Dividend GrowthSeres Therapeutics does not have a long track record of dividend growth. Sustainability and ESG4.6 / 5Environmental Score-1.14 Percentage of Shares Shorted14.47% of the float of Seres Therapeutics has been sold short.Short Interest Ratio / Days to CoverSeres Therapeutics has a short interest ratio ("days to cover") of 5.2.Change versus previous monthShort interest in Seres Therapeutics has recently decreased by 7.30%, indicating that investor sentiment is improving significantly. News and Social Media3.1 / 5News Sentiment1.55 News SentimentSeres Therapeutics has a news sentiment score of 1.55. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.54 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 2 news articles for Seres Therapeutics this week, compared to 2 articles on an average week.Search Interest24 people have searched for MCRB on MarketBeat in the last 30 days. This is an increase of 243% compared to the previous 30 days. Company Ownership0.8 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Seres Therapeutics insiders have not sold or bought any company stock.Percentage Held by InsidersOnly 4.70% of the stock of Seres Therapeutics is held by insiders.Percentage Held by Institutions59.34% of the stock of Seres Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Seres Therapeutics' insider trading history. Receive MCRB Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Seres Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 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MCRB Stock News HeadlinesSeres Therapeutics price target raised to $22 from $14 at CanaccordSeptember 24, 2025 | msn.comSeres Therapeutics, Inc.: Seres Therapeutics Announces Further Constructive Feedback from FDA on SER-155 Phase 2 Study Protocol and Implements Cost Reduction Actions to Extend ...September 23, 2025 | finanznachrichten.deURGENT: The Market's 3 Red Flags Are FlashingThe warning signs that preceded the 2008 crash are reappearing: an irrational NASDAQ bubble, a record-high gold price (signaling fear), and escalating geopolitical risk. A sharp correction might happen tomorrow, and most investors will be caught off guard. Your portfolio is currently exposed.October 5 at 2:00 AM | StockEarnings (Ad)Seres Therapeutics cuts 25% of workforce to extend cash runway into Q2 2026September 23, 2025 | msn.comSeres Therapeutics Advances SER-155 Phase 2 Study Protocol and Initiates Workforce Reduction to Extend Cash RunwaySeptember 23, 2025 | quiverquant.comQSeres Therapeutics Announces Further Constructive Feedback from FDA on SER-155 Phase 2 Study Protocol and Implements Cost Reduction Actions to Extend Cash RunwaySeptember 23, 2025 | globenewswire.comBiggest stock movers Monday: RAPP, MCRB, SATS, QS, SMMT and moreSeptember 8, 2025 | msn.comSeres Therapeutics soars on report of takeover offerSeptember 8, 2025 | msn.comSee More Headlines MCRB Stock Analysis - Frequently Asked Questions How have MCRB shares performed this year? Seres Therapeutics' stock was trading at $16.62 at the beginning of 2025. Since then, MCRB stock has increased by 23.9% and is now trading at $20.59. How were Seres Therapeutics' earnings last quarter? Seres Therapeutics, Inc. (NASDAQ:MCRB) released its earnings results on Wednesday, August, 6th. The biotechnology company reported ($2.27) EPS for the quarter, beating the consensus estimate of ($2.72) by $0.45. Read the conference call transcript. When did Seres Therapeutics' stock split? Shares of Seres Therapeutics reverse split before market open on Tuesday, April 22nd 2025.The 1-20 reverse split was announced on Thursday, April 10th 2025. The number of shares owned by shareholders was adjusted after the closing bell on Monday, April 21st 2025. An investor that had 100 shares of stock prior to the reverse split would have 5 shares after the split. When did Seres Therapeutics IPO? Seres Therapeutics (MCRB) raised $101 million in an IPO on Friday, June 26th 2015. The company issued 6,300,000 shares at $15.00-$17.00 per share. Goldman Sachs and BofA Merrill Lynch acted as the underwriters for the IPO and Leerink Partners and Canaccord Genuity were co-managers. How do I buy shares of Seres Therapeutics? Shares of MCRB stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Seres Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Seres Therapeutics investors own include PayPal (PYPL), NVIDIA (NVDA), Meta Platforms (META), Tesla (TSLA), Micron Technology (MU), QUALCOMM (QCOM) and NIO (NIO). Company Calendar Last Earnings8/06/2025Today10/04/2025Next Earnings (Estimated)11/12/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:MCRB CIK1609809 Webwww.serestherapeutics.com Phone(617) 945-9626FaxN/AEmployees330Year Founded2010Price Target and Rating Average Price Target for Seres Therapeutics$14.33 High Price Target$22.00 Low Price Target$6.00 Potential Upside/Downside-30.4%Consensus RatingReduce Rating Score (0-4)1.60 Research Coverage5 Analysts Profitability EPS (Trailing Twelve Months)($4.60) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income$140 thousand Net MarginsN/A Pretax MarginN/A Return on Equity-350.16% Return on Assets-67.69% Debt Debt-to-Equity RatioN/A Current Ratio1.57 Quick Ratio1.57 Sales & Book Value Annual Sales$126.32 million Price / Sales1.43 Cash FlowN/A Price / Cash FlowN/A Book Value$1.61 per share Price / Book12.79Miscellaneous Outstanding Shares8,750,000Free Float8,344,000Market Cap$180.16 million OptionableOptionable Beta0.19 Social Links 7 Stocks to Buy And Hold ForeverEnter your email address and we'll send you MarketBeat's list of seven stocks and why their long-term outlooks are very promising. 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