| 5/19/2025 | UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC | 288,134 | $5.90M | 0.0% | +13.6% | 0.262% | |
| 5/16/2025 | Woodline Partners LP | 2,442,397 | $50.00M | 0.3% | +0.5% | 2.224% | |
| 5/16/2025 | Fred Alger Management LLC | 27,421 | $561K | 0.0% | -66.0% | 0.025% | |
| 5/16/2025 | Goldman Sachs Group Inc. | 619,563 | $12.68M | 0.0% | -5.4% | 0.564% | |
| 5/16/2025 | Parkman Healthcare Partners LLC | 100,955 | $2.07M | 0.2% | +32.6% | 0.092% | |
| 5/16/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 29,779 | $610K | 0.0% | N/A | 0.027% | |
| 5/16/2025 | Duquesne Family Office LLC | 800,360 | $16.38M | 0.5% | +178.4% | 0.729% | |
| 5/16/2025 | Cutter Capital Management LP | 221,152 | $4.53M | 2.0% | -34.4% | 0.201% | |
| 5/16/2025 | Alliancebernstein L.P. | 2,241,953 | $45.89M | 0.0% | +20.7% | 2.042% | |
| 5/16/2025 | BVF Inc. IL | 59,065 | $1.21M | 0.0% | N/A | 0.054% | |
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| 5/16/2025 | Adage Capital Partners GP L.L.C. | 1,950,650 | $39.93M | 0.1% | +85.8% | 1.776% | |
| 5/15/2025 | RA Capital Management L.P. | 10,138,938 | $207.54M | 3.5% | +14.6% | 9.232% | |
| 5/15/2025 | Frazier Life Sciences Management L.P. | 16,116,418 | $329.90M | 15.1% | +1.3% | 14.676% | |
| 5/15/2025 | Maverick Capital Ltd. | 549,469 | $11.25M | 0.2% | +57.0% | 0.500% | |
| 5/15/2025 | Caption Management LLC | 30,934 | $633K | 0.0% | -341.3% | 0.028% | |
| 5/15/2025 | Quarry LP | 1,200 | $25K | 0.0% | N/A | 0.001% | |
| 5/15/2025 | Siren L.L.C. | 1,912,030 | $39.14M | 2.3% | -8.8% | 1.741% | |
| 5/15/2025 | Trexquant Investment LP | 66,102 | $1.35M | 0.0% | N/A | 0.060% | |
| 5/15/2025 | OMERS ADMINISTRATION Corp | 37,700 | $772K | 0.0% | +83.9% | 0.034% | |
| 5/14/2025 | Wellington Management Group LLP | 3,541,975 | $72.50M | 0.0% | +53.0% | 3.225% | |
| 5/13/2025 | American Century Companies Inc. | 528,830 | $10.83M | 0.0% | +52.6% | 0.482% | |
| 5/13/2025 | Aberdeen Group plc | 376,863 | $7.71M | 0.0% | +110.5% | 0.343% | |
| 5/12/2025 | Invesco Ltd. | 118,934 | $2.44M | 0.0% | -21.0% | 0.108% | |
| 5/12/2025 | Swiss National Bank | 70,900 | $1.45M | 0.0% | -1.5% | 0.065% | |
| 5/9/2025 | CenterBook Partners LP | 222,264 | $4.55M | 0.3% | +6.6% | 0.202% | |
| 5/9/2025 | Deutsche Bank AG | 72,397 | $1.48M | 0.0% | +2,634.0% | 0.066% | |
| 5/9/2025 | DCF Advisers LLC | 172,500 | $3.53M | 1.7% | +93.0% | 0.157% | |
| 5/7/2025 | Bryce Point Capital LLC | 19,653 | $438K | 0.3% | N/A | 0.018% | |
| 5/7/2025 | Zurcher Kantonalbank Zurich Cantonalbank | 5,990 | $123K | 0.0% | +130.4% | 0.005% | |
| 5/7/2025 | HB Wealth Management LLC | 11,247 | $230K | 0.0% | +28.9% | 0.010% | |
| 5/6/2025 | Readystate Asset Management LP | 229,662 | $4.70M | 0.2% | -11.8% | 0.209% | |
| 5/5/2025 | Atle Fund Management AB | 107,783 | $2.21M | 1.0% | -22.4% | 0.098% | |
| 5/5/2025 | Jennison Associates LLC | 3,970,189 | $81.27M | 0.1% | -0.7% | 3.615% | |
| 5/2/2025 | TimesSquare Capital Management LLC | 891,088 | $18.24M | 0.3% | -0.5% | 0.811% | |
| 5/1/2025 | Arizona State Retirement System | 10,486 | $215K | 0.0% | N/A | 0.010% | |
| 4/30/2025 | Alps Advisors Inc. | 77,961 | $1.60M | 0.0% | +4.4% | 0.071% | |
| 4/30/2025 | China Universal Asset Management Co. Ltd. | 22,028 | $451K | 0.0% | +12.5% | 0.020% | |
| 4/25/2025 | Lisanti Capital Growth LLC | 49,110 | $1.01M | 0.3% | +26.9% | 0.045% | |
| 4/24/2025 | Mirae Asset Global Investments Co. Ltd. | 3,675 | $80K | 0.0% | +19.4% | 0.003% | |
| 4/15/2025 | Handelsbanken Fonder AB | 260,000 | $5.32M | 0.0% | +38.7% | 0.237% | |
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| 4/15/2025 | Avanza Fonder AB | 6,205 | $127K | 0.0% | N/A | 0.006% | |
| 3/24/2025 | Wellington Management Group LLP | 2,315,123 | $59.50M | 0.0% | +2,410.4% | 2.108% | |
| 3/18/2025 | California State Teachers Retirement System | 19,404 | $499K | 0.0% | +23.5% | 0.018% | |
| 2/19/2025 | GF Fund Management CO. LTD. | 1,940 | $50K | 0.0% | N/A | 0.002% | |
| 2/18/2025 | Frazier Life Sciences Management L.P. | 15,916,418 | $409.05M | 17.0% | +23.8% | 17.227% | |
| 2/17/2025 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 253,571 | $6.52M | 0.0% | +6.0% | 0.274% | |
| 2/17/2025 | Voloridge Investment Management LLC | 28,041 | $721K | 0.0% | N/A | 0.030% | |
| 2/17/2025 | Woodline Partners LP | 2,430,782 | $62.47M | 0.4% | +108.7% | 2.631% | |
| 2/17/2025 | Two Sigma Advisers LP | 74,300 | $1.91M | 0.0% | -23.8% | 0.080% | |
| 2/17/2025 | Two Sigma Investments LP | 89,589 | $2.30M | 0.0% | -61.1% | 0.097% | |
| 2/17/2025 | Polar Capital Holdings Plc | 1,750,000 | $44.98M | 0.3% | +16.3% | 1.894% | |
| 2/17/2025 | Parkman Healthcare Partners LLC | 76,116 | $1.96M | 0.3% | -27.7% | 0.082% | |
| 2/17/2025 | OMERS ADMINISTRATION Corp | 20,500 | $527K | 0.0% | N/A | 0.022% | |
| 2/17/2025 | Maven Securities LTD | 150,000 | $3.86M | 0.1% | N/A | 0.162% | |
| 2/17/2025 | Millennium Management LLC | 494,230 | $12.70M | 0.0% | +2,850.8% | 0.535% | |
| 2/17/2025 | Lazard Asset Management LLC | 28,517 | $732K | 0.0% | N/A | 0.031% | |
| 2/17/2025 | Janus Henderson Group PLC | 1,736,777 | $44.65M | 0.0% | +12.7% | 1.880% | |
| 2/17/2025 | Fcpm Iii Services B.V. | 10,597,181 | $272.35M | 46.2% | -10.4% | 11.470% | |
| 2/17/2025 | Fred Alger Management LLC | 80,579 | $2.07M | 0.0% | N/A | 0.087% | |
| 2/17/2025 | Deerfield Management Company L.P. Series C | 4,314,340 | $110.88M | 2.1% | +378.4% | 4.670% | |
| 2/17/2025 | Crestline Management LP | 35,068 | $901K | 0.0% | N/A | 0.038% | |
| 2/17/2025 | Cutter Capital Management LP | 337,152 | $8.67M | 3.6% | N/A | 0.365% | |
| 2/17/2025 | Bellevue Group AG | 25,000 | $642K | 0.0% | +224.7% | 0.027% | |
| 2/17/2025 | Bank of America Corp DE | 43,529 | $1.12M | 0.0% | +1,506.2% | 0.047% | |
| 2/17/2025 | BNP Paribas Financial Markets | 35,657 | $916K | 0.0% | N/A | 0.039% | |
| 2/17/2025 | Alyeska Investment Group L.P. | 114,707 | $2.95M | 0.0% | -62.8% | 0.124% | |
| 2/17/2025 | ArrowMark Colorado Holdings LLC | 345,048 | $8.87M | 0.1% | -2.8% | 0.373% | |
| 2/17/2025 | AXA S.A. | 278,266 | $7.15M | 0.0% | -19.3% | 0.301% | |
| 2/17/2025 | Acuta Capital Partners LLC | 50,000 | $1.29M | 1.3% | N/A | 0.054% | |
| 2/14/2025 | RA Capital Management L.P. | 8,845,000 | $227.32M | 3.0% | +9.7% | 9.574% | |
| 2/14/2025 | Monashee Investment Management LLC | 50,000 | $1.29M | 0.2% | N/A | 0.054% | |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 20,382 | $524K | 0.0% | N/A | 0.022% | |
| 2/14/2025 | Northern Trust Corp | 21,627 | $556K | 0.0% | N/A | 0.023% | |
| 2/14/2025 | The Manufacturers Life Insurance Company | 8,616 | $221K | 0.0% | N/A | 0.009% | |
| 2/14/2025 | Tudor Investment Corp ET AL | 52,208 | $1.34M | 0.0% | N/A | 0.057% | |
| 2/14/2025 | Decheng Capital LLC | 770,000 | $19.79M | 4.2% | +30.5% | 0.833% | |
| 2/14/2025 | Virtus ETF Advisers LLC | 2,834 | $73K | 0.0% | -40.2% | 0.003% | |
| 2/14/2025 | Gilder Gagnon Howe & Co. LLC | 29,871 | $768K | 0.0% | +24.9% | 0.032% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 1,050,000 | $26.99M | 0.0% | -23.9% | 1.136% | |
| 2/14/2025 | GMT Capital Corp | 285,136 | $7.33M | 0.4% | -65.6% | 0.309% | |
| 2/14/2025 | Slate Path Capital LP | 319,000 | $8.20M | 0.1% | N/A | 0.345% | |
| 2/14/2025 | Eversept Partners LP | 275,362 | $7.08M | 0.6% | -10.4% | 0.298% | |
| 2/14/2025 | Rock Springs Capital Management LP | 767,522 | $19.73M | 0.8% | +117.2% | 0.831% | |
| 2/14/2025 | Bain Capital Life Sciences Investors LLC | 10,719,110 | $275.48M | 32.4% | +2.3% | 11.602% | |
| 2/14/2025 | Tower Research Capital LLC TRC | 1,297 | $33K | 0.0% | -83.3% | 0.001% | |
| 2/14/2025 | Capital World Investors | 1,016,076 | $26.11M | 0.0% | N/A | 1.100% | |
| 2/14/2025 | Capital International Investors | 2,062,535 | $53.01M | 0.0% | N/A | 2.233% | |
| 2/13/2025 | Marshall Wace LLP | 288,446 | $7.41M | 0.0% | +161.9% | 0.312% | |
| 2/13/2025 | Affinity Asset Advisors LLC | 425,000 | $10.92M | 1.5% | -10.0% | 0.460% | |
| 2/13/2025 | Jump Financial LLC | 25,401 | $653K | 0.0% | N/A | 0.027% | |
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| 2/13/2025 | Walleye Capital LLC | 10,506 | $270K | 0.0% | -77.6% | 0.011% | |
| 2/13/2025 | Barclays PLC | 16,713 | $429K | 0.0% | +120.0% | 0.018% | |
| 2/13/2025 | Kennedy Capital Management LLC | 7,945 | $204K | 0.0% | -43.4% | 0.009% | |
| 2/13/2025 | CenterBook Partners LP | 208,589 | $5.36M | 0.3% | +143.4% | 0.226% | |
| 2/13/2025 | Legal & General Group Plc | 22,946 | $590K | 0.0% | +24.8% | 0.025% | |
| 2/13/2025 | Invesco Ltd. | 150,559 | $3.87M | 0.0% | N/A | 0.163% | |
| 2/13/2025 | Envestnet Asset Management Inc. | 9,359 | $241K | 0.0% | -48.3% | 0.010% | |
| 2/13/2025 | Ovata Capital Management Ltd | 150,000 | $3.86M | 1.5% | N/A | 0.162% | |
| 2/13/2025 | Pamalican Asset Management Ltd | 30,000 | $771K | 0.3% | N/A | 0.032% | |
| 2/12/2025 | Cinctive Capital Management LP | 9,516 | $245K | 0.0% | -85.7% | 0.010% | |
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