NASDAQ:PBYI Puma Biotechnology (PBYI) Stock Price, News & Analysis $2.91 -0.16 (-5.21%) Closing price 05/9/2025 04:00 PM EasternExtended Trading$2.96 +0.04 (+1.55%) As of 08:02 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Puma Biotechnology Stock (NASDAQ:PBYI) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get Puma Biotechnology alerts:Sign Up Key Stats Today's Range$2.90▼$3.3050-Day Range$2.74▼$3.6252-Week Range$2.23▼$5.20Volume475,098 shsAverage Volume440,927 shsMarket Capitalization$144.43 millionP/E Ratio6.06Dividend YieldN/APrice Target$7.00Consensus RatingBuy Company OverviewPuma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. The company offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine. It also develops alisertib, a small molecule inhibitor of aurora kinase A for the treatment of hormone receptor positive breast cancer, triple negative breast cancer, small cell lung cancer, and head and neck cancer. The company sells its products through specialty pharmacy and distributor networks. It has license agreements with Pfizer Inc. for the development, manufacture, and commercialization of neratinib (oral), neratinib (intravenous), PB357, and related compounds; and Takeda Pharmaceutical Company Limited for the research, development, and commercialization of alisertib, as well as sub-license agreements with Specialised Therapeutics Asia Pte Ltd., Medison Pharma Ltd., Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. The company was founded in 2010 and is headquartered in Los Angeles, California.Read More… Puma Biotechnology Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks78th Percentile Overall ScorePBYI MarketRank™: Puma Biotechnology scored higher than 78% of companies evaluated by MarketBeat, and ranked 210th out of 916 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.5 / 5Analyst RatingBuy Consensus RatingPuma Biotechnology has received a consensus rating of Buy. The company's average rating score is 3.00, and is based on 1 buy rating, no hold ratings, and no sell ratings.Amount of Analyst CoveragePuma Biotechnology has only been the subject of 1 research reports in the past 90 days.Read more about Puma Biotechnology's stock forecast and price target. Earnings and Valuation3.1 / 5Proj. Earnings Growth22.58% Earnings GrowthEarnings for Puma Biotechnology are expected to grow by 22.58% in the coming year, from $0.31 to $0.38 per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Puma Biotechnology is 6.06, which means that it is trading at a less expensive P/E ratio than the market average P/E ratio of about 22.38.Price to Earnings Ratio vs. SectorThe P/E ratio of Puma Biotechnology is 6.06, which means that it is trading at a less expensive P/E ratio than the Medical sector average P/E ratio of about 25.15.Price to Book Value per Share RatioPuma Biotechnology has a P/B Ratio of 2.60. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted7.39% of the float of Puma Biotechnology has been sold short.Short Interest Ratio / Days to CoverPuma Biotechnology has a short interest ratio ("days to cover") of 7.7.Change versus previous monthShort interest in Puma Biotechnology has recently decreased by 0.35%, indicating that investor sentiment is improving. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldPuma Biotechnology does not currently pay a dividend.Dividend GrowthPuma Biotechnology does not have a long track record of dividend growth. Sustainability and ESGN/AEnvironmental ScoreN/A Percentage of Shares Shorted7.39% of the float of Puma Biotechnology has been sold short.Short Interest Ratio / Days to CoverPuma Biotechnology has a short interest ratio ("days to cover") of 7.7.Change versus previous monthShort interest in Puma Biotechnology has recently decreased by 0.35%, indicating that investor sentiment is improving. News and Social Media2.6 / 5News Sentiment0.72 News SentimentPuma Biotechnology has a news sentiment score of 0.72. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.86 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 10 news articles for Puma Biotechnology this week, compared to 2 articles on an average week.Search Interest1 people have searched for PBYI on MarketBeat in the last 30 days. MarketBeat FollowsOnly 1 people have added Puma Biotechnology to their MarketBeat watchlist in the last 30 days. This is a decrease of -50% compared to the previous 30 days. Company Ownership3.3 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Puma Biotechnology insiders have not sold or bought any company stock.Percentage Held by Insiders23.70% of the stock of Puma Biotechnology is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by Institutions61.29% of the stock of Puma Biotechnology is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Puma Biotechnology's insider trading history. Receive PBYI Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Puma Biotechnology and its competitors with MarketBeat's FREE daily newsletter. Email Address PBYI Stock News HeadlinesPuma Biotech CCO Jeff Ludwig departs, no replacement namedMay 10 at 10:44 PM | uk.investing.comPuma Biotechnology targets $192M-$198M NERLYNX revenue for 2025 amid strategic effortsMay 9 at 1:05 PM | msn.comSilver’s 332% Surge?Silver has quietly become one of the most promising investments of this cycle. Russia is now stockpiling silver for its reserves. Bank of America believes it could hit $50 per ounce. And historical trends suggest that silver surges after Fed rate cuts—by as much as 332%. This free report breaks it all down—and shows how you may qualify for up to $15,000 in bonus silver.May 12, 2025 | Lear Capital (Ad)Puma Biotechnology Inc (PBYI) Q1 2025 Earnings Call Highlights: Revenue Growth Amidst ChallengesMay 9 at 2:47 AM | gurufocus.comPuma Biotechnology Stock Short Interest Report | NASDAQ:PBYI | BenzingaMay 8, 2025 | benzinga.comZacks Research Brokers Reduce Earnings Estimates for PBYIMay 4, 2025 | americanbankingnews.comQ1 EPS Forecast for Puma Biotechnology Raised by AnalystMay 3, 2025 | americanbankingnews.comPuma Biotechnology (NASDAQ:PBYI) Lowered to Buy Rating by StockNews.comMay 3, 2025 | americanbankingnews.comSee More Headlines PBYI Stock Analysis - Frequently Asked Questions How have PBYI shares performed this year? Puma Biotechnology's stock was trading at $3.05 on January 1st, 2025. Since then, PBYI stock has decreased by 4.6% and is now trading at $2.91. View the best growth stocks for 2025 here. How were Puma Biotechnology's earnings last quarter? Puma Biotechnology, Inc. (NASDAQ:PBYI) announced its earnings results on Thursday, February, 27th. The biopharmaceutical company reported $0.39 earnings per share for the quarter, beating analysts' consensus estimates of $0.10 by $0.29. The biopharmaceutical company earned $59.10 million during the quarter, compared to the consensus estimate of $52.50 million. Puma Biotechnology had a net margin of 9.56% and a trailing twelve-month return on equity of 41.60%. Read the conference call transcript. Who are Puma Biotechnology's major shareholders? Puma Biotechnology's top institutional shareholders include Bank of New York Mellon Corp (0.69%), Federated Hermes Inc. (0.40%), Mackenzie Financial Corp (0.32%) and XTX Topco Ltd (0.25%). Insiders that own company stock include Alan H Auerbach, Maximo F Nougues, Jeffrey Jerome Ludwig, Alvin F Wong, Douglas M Hunt, Michael Patrick Miller and Troy Edward Wilson. View institutional ownership trends. How do I buy shares of Puma Biotechnology? Shares of PBYI stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Puma Biotechnology own? Based on aggregate information from My MarketBeat watchlists, some other companies that Puma Biotechnology investors own include Incyte (INCY), BioMarin Pharmaceutical (BMRN), (MDVN) (MDVN), First Solar (FSLR), Humana (HUM), American Water Works (AWK) and NVIDIA (NVDA). Company Calendar Last Earnings2/27/2025Today5/12/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry Pharmaceutical preparations Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:PBYI CIK1401667 Webwww.pumabiotechnology.com Phone(424) 248-6500Fax424-248-6501Employees200Year FoundedN/APrice Target and Rating Average Stock Price Target$7.00 High Stock Price Target$7.00 Low Stock Price Target$7.00 Potential Upside/Downside+140.5%Consensus RatingBuy Rating Score (0-4)3.00 Research Coverage1 Analysts Profitability EPS (Most Recent Fiscal Year)$0.77 Trailing P/E Ratio6.06 Forward P/E Ratio9.39 P/E GrowthN/ANet Income$21.59 million Net Margins9.56% Pretax Margin10.13% Return on Equity41.60% Return on Assets10.71% Debt Debt-to-Equity Ratio0.46 Current Ratio1.42 Quick Ratio1.40 Sales & Book Value Annual Sales$230.47 million Price / Sales0.63 Cash Flow$0.69 per share Price / Cash Flow4.19 Book Value$1.12 per share Price / Book2.60Miscellaneous Outstanding Shares49,631,000Free Float37,454,000Market Cap$144.43 million OptionableOptionable Beta1.29 Social Links Elon Musk's Next MoveExplore Elon Musk’s boldest ventures yet—from AI and autonomy to space colonization—and find out how investors can ride the next wave of innovation.Get This Free Report This page (NASDAQ:PBYI) was last updated on 5/12/2025 by MarketBeat.com Staff From Our PartnersThe one deadline Elon can't afford to miss...For years, Elon Musk made headlines for blowing past deadlines — so often that investors coined a nickname for...Brownstone Research | SponsoredThink NVDA’s run was epic? 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