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Puma Biotechnology (PBYI) Competitors

Puma Biotechnology logo
$7.98 -0.03 (-0.37%)
Closing price 07/24/2026 04:00 PM Eastern
Extended Trading
$7.90 -0.08 (-0.94%)
As of 07/24/2026 07:34 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

PBYI vs. ADMA, CTMX, TRDA, AAPG, and ZYME

Should you buy Puma Biotechnology stock or one of its competitors? MarketBeat compares Puma Biotechnology with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Puma Biotechnology include ADMA Biologics (ADMA), CytomX Therapeutics (CTMX), Entrada Therapeutics (TRDA), Ascentage Pharma Group International (AAPG), and Zymeworks (ZYME). These companies are all part of the "pharmaceutical products" industry.

How does Puma Biotechnology compare to ADMA Biologics?

Puma Biotechnology (NASDAQ:PBYI) and ADMA Biologics (NASDAQ:ADMA) are both small-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their valuation, media sentiment, analyst recommendations, risk, dividends, institutional ownership, earnings and profitability.

In the previous week, ADMA Biologics had 34 more articles in the media than Puma Biotechnology. MarketBeat recorded 36 mentions for ADMA Biologics and 2 mentions for Puma Biotechnology. Puma Biotechnology's average media sentiment score of 0.94 beat ADMA Biologics' score of 0.07 indicating that Puma Biotechnology is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Puma Biotechnology
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
ADMA Biologics
1 Very Positive mention(s)
1 Positive mention(s)
33 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

61.3% of Puma Biotechnology shares are held by institutional investors. Comparatively, 75.7% of ADMA Biologics shares are held by institutional investors. 22.2% of Puma Biotechnology shares are held by company insiders. Comparatively, 3.9% of ADMA Biologics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

ADMA Biologics has a net margin of 32.43% compared to Puma Biotechnology's net margin of 10.69%. ADMA Biologics' return on equity of 39.98% beat Puma Biotechnology's return on equity.

Company Net Margins Return on Equity Return on Assets
Puma Biotechnology10.69% 20.30% 12.05%
ADMA Biologics 32.43%39.98%28.08%

ADMA Biologics has higher revenue and earnings than Puma Biotechnology. ADMA Biologics is trading at a lower price-to-earnings ratio than Puma Biotechnology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Puma Biotechnology$228.40M1.78$31.11M$0.4816.63
ADMA Biologics$510.17M3.76$146.93M$0.6812.16

ADMA Biologics has a consensus price target of $18.67, suggesting a potential upside of 125.72%. Given ADMA Biologics' stronger consensus rating and higher possible upside, analysts plainly believe ADMA Biologics is more favorable than Puma Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Puma Biotechnology
0 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00
ADMA Biologics
0 Sell rating(s)
3 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50

Puma Biotechnology has a beta of 1.2, meaning that its stock price is 20% more volatile than the broader market. Comparatively, ADMA Biologics has a beta of 0.73, meaning that its stock price is 27% less volatile than the broader market.

Summary

ADMA Biologics beats Puma Biotechnology on 12 of the 16 factors compared between the two stocks.

How does Puma Biotechnology compare to CytomX Therapeutics?

CytomX Therapeutics (NASDAQ:CTMX) and Puma Biotechnology (NASDAQ:PBYI) are both small-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their institutional ownership, earnings, risk, dividends, media sentiment, valuation, analyst recommendations and profitability.

67.8% of CytomX Therapeutics shares are held by institutional investors. Comparatively, 61.3% of Puma Biotechnology shares are held by institutional investors. 3.8% of CytomX Therapeutics shares are held by insiders. Comparatively, 22.2% of Puma Biotechnology shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

CytomX Therapeutics currently has a consensus target price of $12.10, indicating a potential upside of 273.46%. Given CytomX Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe CytomX Therapeutics is more favorable than Puma Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
CytomX Therapeutics
1 Sell rating(s)
0 Hold rating(s)
9 Buy rating(s)
2 Strong Buy rating(s)
3.00
Puma Biotechnology
0 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00

Puma Biotechnology has higher revenue and earnings than CytomX Therapeutics. CytomX Therapeutics is trading at a lower price-to-earnings ratio than Puma Biotechnology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
CytomX Therapeutics$76.20M7.24-$17.37M-$0.41N/A
Puma Biotechnology$228.40M1.78$31.11M$0.4816.63

In the previous week, CytomX Therapeutics had 2 more articles in the media than Puma Biotechnology. MarketBeat recorded 4 mentions for CytomX Therapeutics and 2 mentions for Puma Biotechnology. CytomX Therapeutics' average media sentiment score of 1.23 beat Puma Biotechnology's score of 0.94 indicating that CytomX Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
CytomX Therapeutics
1 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Puma Biotechnology
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Puma Biotechnology has a net margin of 10.69% compared to CytomX Therapeutics' net margin of -166.40%. Puma Biotechnology's return on equity of 20.30% beat CytomX Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
CytomX Therapeutics-166.40% -36.61% -28.02%
Puma Biotechnology 10.69%20.30%12.05%

CytomX Therapeutics has a beta of 2.08, suggesting that its stock price is 108% more volatile than the broader market. Comparatively, Puma Biotechnology has a beta of 1.2, suggesting that its stock price is 20% more volatile than the broader market.

Summary

CytomX Therapeutics beats Puma Biotechnology on 9 of the 17 factors compared between the two stocks.

How does Puma Biotechnology compare to Entrada Therapeutics?

Entrada Therapeutics (NASDAQ:TRDA) and Puma Biotechnology (NASDAQ:PBYI) are both small-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their analyst recommendations, valuation, media sentiment, profitability, risk, dividends, earnings and institutional ownership.

Puma Biotechnology has higher revenue and earnings than Entrada Therapeutics. Entrada Therapeutics is trading at a lower price-to-earnings ratio than Puma Biotechnology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Entrada Therapeutics$5.74M39.58-$143.75M-$3.99N/A
Puma Biotechnology$228.40M1.78$31.11M$0.4816.63

In the previous week, Puma Biotechnology had 1 more articles in the media than Entrada Therapeutics. MarketBeat recorded 2 mentions for Puma Biotechnology and 1 mentions for Entrada Therapeutics. Entrada Therapeutics' average media sentiment score of 1.89 beat Puma Biotechnology's score of 0.94 indicating that Entrada Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Entrada Therapeutics Very Positive
Puma Biotechnology Positive

Puma Biotechnology has a net margin of 10.69% compared to Entrada Therapeutics' net margin of -2,895.05%. Puma Biotechnology's return on equity of 20.30% beat Entrada Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Entrada Therapeutics-2,895.05% -51.22% -42.20%
Puma Biotechnology 10.69%20.30%12.05%

Entrada Therapeutics presently has a consensus price target of $17.50, indicating a potential upside of 199.15%. Given Entrada Therapeutics' stronger consensus rating and higher probable upside, equities research analysts plainly believe Entrada Therapeutics is more favorable than Puma Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Entrada Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33
Puma Biotechnology
0 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00

86.4% of Entrada Therapeutics shares are owned by institutional investors. Comparatively, 61.3% of Puma Biotechnology shares are owned by institutional investors. 9.5% of Entrada Therapeutics shares are owned by company insiders. Comparatively, 22.2% of Puma Biotechnology shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Entrada Therapeutics has a beta of -0.26, suggesting that its stock price is 126% less volatile than the broader market. Comparatively, Puma Biotechnology has a beta of 1.2, suggesting that its stock price is 20% more volatile than the broader market.

Summary

Puma Biotechnology beats Entrada Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Puma Biotechnology compare to Ascentage Pharma Group International?

Puma Biotechnology (NASDAQ:PBYI) and Ascentage Pharma Group International (NASDAQ:AAPG) are both small-cap medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their profitability, analyst recommendations, media sentiment, earnings, valuation, institutional ownership, risk and dividends.

Puma Biotechnology has a net margin of 10.69% compared to Ascentage Pharma Group International's net margin of 0.00%. Puma Biotechnology's return on equity of 20.30% beat Ascentage Pharma Group International's return on equity.

Company Net Margins Return on Equity Return on Assets
Puma Biotechnology10.69% 20.30% 12.05%
Ascentage Pharma Group International N/A N/A N/A

Puma Biotechnology has a beta of 1.2, indicating that its stock price is 20% more volatile than the broader market. Comparatively, Ascentage Pharma Group International has a beta of 0.09, indicating that its stock price is 91% less volatile than the broader market.

Puma Biotechnology has higher earnings, but lower revenue than Ascentage Pharma Group International.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Puma Biotechnology$228.40M1.78$31.11M$0.4816.63
Ascentage Pharma Group International$574.12M2.98-$177.71MN/AN/A

Ascentage Pharma Group International has a consensus target price of $46.43, suggesting a potential upside of 153.85%. Given Ascentage Pharma Group International's stronger consensus rating and higher possible upside, analysts plainly believe Ascentage Pharma Group International is more favorable than Puma Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Puma Biotechnology
0 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00
Ascentage Pharma Group International
0 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.20

In the previous week, Ascentage Pharma Group International had 3 more articles in the media than Puma Biotechnology. MarketBeat recorded 5 mentions for Ascentage Pharma Group International and 2 mentions for Puma Biotechnology. Ascentage Pharma Group International's average media sentiment score of 1.16 beat Puma Biotechnology's score of 0.94 indicating that Ascentage Pharma Group International is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Puma Biotechnology
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Ascentage Pharma Group International
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

61.3% of Puma Biotechnology shares are owned by institutional investors. 22.2% of Puma Biotechnology shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Summary

Ascentage Pharma Group International beats Puma Biotechnology on 8 of the 15 factors compared between the two stocks.

How does Puma Biotechnology compare to Zymeworks?

Puma Biotechnology (NASDAQ:PBYI) and Zymeworks (NASDAQ:ZYME) are both small-cap pharmaceutical products companies, but which is the superior stock? We will compare the two businesses based on the strength of their analyst recommendations, risk, profitability, dividends, earnings, valuation, institutional ownership and media sentiment.

Puma Biotechnology has higher revenue and earnings than Zymeworks. Zymeworks is trading at a lower price-to-earnings ratio than Puma Biotechnology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Puma Biotechnology$228.40M1.78$31.11M$0.4816.63
Zymeworks$105.96M15.75-$81.13M-$1.37N/A

Puma Biotechnology has a net margin of 10.69% compared to Zymeworks' net margin of -126.92%. Puma Biotechnology's return on equity of 20.30% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Puma Biotechnology10.69% 20.30% 12.05%
Zymeworks -126.92%-37.97%-25.31%

Zymeworks has a consensus price target of $37.33, indicating a potential upside of 63.31%. Given Zymeworks' stronger consensus rating and higher probable upside, analysts clearly believe Zymeworks is more favorable than Puma Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Puma Biotechnology
0 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.82

61.3% of Puma Biotechnology shares are owned by institutional investors. Comparatively, 92.9% of Zymeworks shares are owned by institutional investors. 22.2% of Puma Biotechnology shares are owned by company insiders. Comparatively, 33.5% of Zymeworks shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Puma Biotechnology has a beta of 1.2, suggesting that its stock price is 20% more volatile than the broader market. Comparatively, Zymeworks has a beta of 1.13, suggesting that its stock price is 13% more volatile than the broader market.

In the previous week, Puma Biotechnology had 1 more articles in the media than Zymeworks. MarketBeat recorded 2 mentions for Puma Biotechnology and 1 mentions for Zymeworks. Zymeworks' average media sentiment score of 1.89 beat Puma Biotechnology's score of 0.94 indicating that Zymeworks is being referred to more favorably in the news media.

Company Overall Sentiment
Puma Biotechnology Positive
Zymeworks Very Positive

Summary

Puma Biotechnology beats Zymeworks on 9 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PBYI and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PBYI vs. The Competition

MetricPuma BiotechnologyMED IndustryMedical SectorNASDAQ Exchange
Market Cap$407.70M$3.67B$6.87B$12.26B
Dividend YieldN/A2.19%2.67%9.79%
P/E Ratio16.6321.2927.1123.64
Price / Sales1.78161.63511.1389.90
Price / Cash9.60157.9050.5459.64
Price / Book3.087.8810.286.07
Net Income$31.11M$23.86M$3.60B$331.99M
7 Day Performance-6.45%-3.82%-1.27%-0.63%
1 Month Performance4.04%-2.61%-0.37%-2.00%
1 Year Performance143.29%32.79%18.30%13.62%

Puma Biotechnology Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PBYI
Puma Biotechnology
0.989 of 5 stars
$7.98
-0.4%
N/A+134.7%$407.70M$228.40M16.63200
ADMA
ADMA Biologics
4.7447 of 5 stars
$8.66
-1.1%
$18.67
+115.7%
-52.2%$2.01B$509.86M12.73530
CTMX
CytomX Therapeutics
2.4553 of 5 stars
$3.41
-3.0%
$12.10
+254.5%
+35.6%$579.50M$76.20MN/A170
TRDA
Entrada Therapeutics
3.5071 of 5 stars
$6.43
+1.3%
$17.50
+172.4%
-8.5%$249.61M$25.42MN/A110
AAPG
Ascentage Pharma Group International
4.5841 of 5 stars
$18.75
+2.1%
$46.43
+147.6%
-54.0%$1.75B$82.10MN/A600

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This page (NASDAQ:PBYI) was last updated on 7/25/2026 by MarketBeat.com Staff.
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