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Puma Biotechnology (PBYI) Competitors

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$8.26 0.00 (0.00%)
Closing price 07/2/2026 04:00 PM Eastern
Extended Trading
$8.26 0.00 (0.00%)
As of 07/2/2026 05:41 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

PBYI vs. ADMA, CTMX, TRDA, MAZE, and AAPG

Should you buy Puma Biotechnology stock or one of its competitors? MarketBeat compares Puma Biotechnology with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Puma Biotechnology include ADMA Biologics (ADMA), CytomX Therapeutics (CTMX), Entrada Therapeutics (TRDA), Maze Therapeutics (MAZE), and Ascentage Pharma Group International (AAPG). These companies are all part of the "pharmaceutical products" industry.

How does Puma Biotechnology compare to ADMA Biologics?

Puma Biotechnology (NASDAQ:PBYI) and ADMA Biologics (NASDAQ:ADMA) are both medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their profitability, valuation, media sentiment, risk, earnings, analyst recommendations, dividends and institutional ownership.

ADMA Biologics has a consensus price target of $19.67, indicating a potential upside of 119.74%. Given ADMA Biologics' stronger consensus rating and higher possible upside, analysts clearly believe ADMA Biologics is more favorable than Puma Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Puma Biotechnology
0 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00
ADMA Biologics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33

In the previous week, ADMA Biologics had 28 more articles in the media than Puma Biotechnology. MarketBeat recorded 28 mentions for ADMA Biologics and 0 mentions for Puma Biotechnology. ADMA Biologics' average media sentiment score of 0.06 beat Puma Biotechnology's score of 0.00 indicating that ADMA Biologics is being referred to more favorably in the news media.

Company Overall Sentiment
Puma Biotechnology Neutral
ADMA Biologics Neutral

ADMA Biologics has a net margin of 32.43% compared to Puma Biotechnology's net margin of 10.69%. ADMA Biologics' return on equity of 39.98% beat Puma Biotechnology's return on equity.

Company Net Margins Return on Equity Return on Assets
Puma Biotechnology10.69% 20.30% 12.05%
ADMA Biologics 32.43%39.98%28.08%

Puma Biotechnology has a beta of 1.2, meaning that its stock price is 20% more volatile than the broader market. Comparatively, ADMA Biologics has a beta of 0.73, meaning that its stock price is 27% less volatile than the broader market.

ADMA Biologics has higher revenue and earnings than Puma Biotechnology. ADMA Biologics is trading at a lower price-to-earnings ratio than Puma Biotechnology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Puma Biotechnology$227.18M1.85$31.11M$0.4817.21
ADMA Biologics$509.86M4.07$146.93M$0.6813.16

61.3% of Puma Biotechnology shares are held by institutional investors. Comparatively, 75.7% of ADMA Biologics shares are held by institutional investors. 22.2% of Puma Biotechnology shares are held by company insiders. Comparatively, 3.9% of ADMA Biologics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Summary

ADMA Biologics beats Puma Biotechnology on 13 of the 16 factors compared between the two stocks.

How does Puma Biotechnology compare to CytomX Therapeutics?

CytomX Therapeutics (NASDAQ:CTMX) and Puma Biotechnology (NASDAQ:PBYI) are both small-cap medical companies, but which is the better business? We will compare the two companies based on the strength of their institutional ownership, analyst recommendations, profitability, media sentiment, risk, valuation, dividends and earnings.

In the previous week, CytomX Therapeutics' average media sentiment score of 0.00 equaled Puma Biotechnology'saverage media sentiment score.

Company Overall Sentiment
CytomX Therapeutics Neutral
Puma Biotechnology Neutral

Puma Biotechnology has higher revenue and earnings than CytomX Therapeutics. CytomX Therapeutics is trading at a lower price-to-earnings ratio than Puma Biotechnology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
CytomX Therapeutics$35.54M18.29-$17.37M-$0.41N/A
Puma Biotechnology$227.18M1.85$31.11M$0.4817.21

67.8% of CytomX Therapeutics shares are held by institutional investors. Comparatively, 61.3% of Puma Biotechnology shares are held by institutional investors. 3.8% of CytomX Therapeutics shares are held by company insiders. Comparatively, 22.2% of Puma Biotechnology shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

CytomX Therapeutics currently has a consensus price target of $12.10, suggesting a potential upside of 216.75%. Given CytomX Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe CytomX Therapeutics is more favorable than Puma Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
CytomX Therapeutics
1 Sell rating(s)
0 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.91
Puma Biotechnology
0 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00

Puma Biotechnology has a net margin of 10.69% compared to CytomX Therapeutics' net margin of -166.40%. Puma Biotechnology's return on equity of 20.30% beat CytomX Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
CytomX Therapeutics-166.40% -36.61% -28.02%
Puma Biotechnology 10.69%20.30%12.05%

CytomX Therapeutics has a beta of 2.08, suggesting that its stock price is 108% more volatile than the broader market. Comparatively, Puma Biotechnology has a beta of 1.2, suggesting that its stock price is 20% more volatile than the broader market.

Summary

Puma Biotechnology beats CytomX Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Puma Biotechnology compare to Entrada Therapeutics?

Entrada Therapeutics (NASDAQ:TRDA) and Puma Biotechnology (NASDAQ:PBYI) are both small-cap medical companies, but which is the better investment? We will compare the two companies based on the strength of their institutional ownership, analyst recommendations, valuation, profitability, media sentiment, risk, dividends and earnings.

86.4% of Entrada Therapeutics shares are held by institutional investors. Comparatively, 61.3% of Puma Biotechnology shares are held by institutional investors. 9.5% of Entrada Therapeutics shares are held by insiders. Comparatively, 22.2% of Puma Biotechnology shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Entrada Therapeutics has a beta of -0.26, meaning that its share price is 126% less volatile than the broader market. Comparatively, Puma Biotechnology has a beta of 1.2, meaning that its share price is 20% more volatile than the broader market.

In the previous week, Entrada Therapeutics' average media sentiment score of 0.00 equaled Puma Biotechnology'saverage media sentiment score.

Company Overall Sentiment
Entrada Therapeutics Neutral
Puma Biotechnology Neutral

Entrada Therapeutics presently has a consensus target price of $17.50, suggesting a potential upside of 126.68%. Given Entrada Therapeutics' stronger consensus rating and higher probable upside, equities analysts clearly believe Entrada Therapeutics is more favorable than Puma Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Entrada Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33
Puma Biotechnology
0 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00

Puma Biotechnology has higher revenue and earnings than Entrada Therapeutics. Entrada Therapeutics is trading at a lower price-to-earnings ratio than Puma Biotechnology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Entrada Therapeutics$25.42M11.79-$143.75M-$3.99N/A
Puma Biotechnology$227.18M1.85$31.11M$0.4817.21

Puma Biotechnology has a net margin of 10.69% compared to Entrada Therapeutics' net margin of -2,895.05%. Puma Biotechnology's return on equity of 20.30% beat Entrada Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Entrada Therapeutics-2,895.05% -51.22% -42.20%
Puma Biotechnology 10.69%20.30%12.05%

Summary

Puma Biotechnology beats Entrada Therapeutics on 9 of the 14 factors compared between the two stocks.

How does Puma Biotechnology compare to Maze Therapeutics?

Puma Biotechnology (NASDAQ:PBYI) and Maze Therapeutics (NASDAQ:MAZE) are both small-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their profitability, media sentiment, earnings, institutional ownership, dividends, analyst recommendations, valuation and risk.

Maze Therapeutics has a consensus price target of $66.00, indicating a potential upside of 111.13%. Given Maze Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Maze Therapeutics is more favorable than Puma Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Puma Biotechnology
0 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00
Maze Therapeutics
1 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.00

Puma Biotechnology has a net margin of 10.69% compared to Maze Therapeutics' net margin of 0.00%. Puma Biotechnology's return on equity of 20.30% beat Maze Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Puma Biotechnology10.69% 20.30% 12.05%
Maze Therapeutics N/A -36.62%-31.78%

61.3% of Puma Biotechnology shares are owned by institutional investors. 22.2% of Puma Biotechnology shares are owned by company insiders. Comparatively, 5.3% of Maze Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Puma Biotechnology has higher revenue and earnings than Maze Therapeutics. Maze Therapeutics is trading at a lower price-to-earnings ratio than Puma Biotechnology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Puma Biotechnology$227.18M1.85$31.11M$0.4817.21
Maze Therapeutics$167.50M10.33-$131.12M-$2.53N/A

In the previous week, Maze Therapeutics had 8 more articles in the media than Puma Biotechnology. MarketBeat recorded 8 mentions for Maze Therapeutics and 0 mentions for Puma Biotechnology. Puma Biotechnology's average media sentiment score of 0.00 beat Maze Therapeutics' score of -0.20 indicating that Puma Biotechnology is being referred to more favorably in the media.

Company Overall Sentiment
Puma Biotechnology Neutral
Maze Therapeutics Neutral

Puma Biotechnology has a beta of 1.2, suggesting that its share price is 20% more volatile than the broader market. Comparatively, Maze Therapeutics has a beta of 2.14, suggesting that its share price is 114% more volatile than the broader market.

Summary

Puma Biotechnology beats Maze Therapeutics on 10 of the 17 factors compared between the two stocks.

How does Puma Biotechnology compare to Ascentage Pharma Group International?

Puma Biotechnology (NASDAQ:PBYI) and Ascentage Pharma Group International (NASDAQ:AAPG) are both small-cap medical companies, but which is the better stock? We will contrast the two companies based on the strength of their media sentiment, institutional ownership, analyst recommendations, valuation, profitability, earnings, dividends and risk.

Puma Biotechnology has a net margin of 10.69% compared to Ascentage Pharma Group International's net margin of 0.00%. Puma Biotechnology's return on equity of 20.30% beat Ascentage Pharma Group International's return on equity.

Company Net Margins Return on Equity Return on Assets
Puma Biotechnology10.69% 20.30% 12.05%
Ascentage Pharma Group International N/A N/A N/A

Puma Biotechnology has a beta of 1.2, suggesting that its stock price is 20% more volatile than the broader market. Comparatively, Ascentage Pharma Group International has a beta of 0.09, suggesting that its stock price is 91% less volatile than the broader market.

In the previous week, Ascentage Pharma Group International had 3 more articles in the media than Puma Biotechnology. MarketBeat recorded 3 mentions for Ascentage Pharma Group International and 0 mentions for Puma Biotechnology. Puma Biotechnology's average media sentiment score of 0.00 beat Ascentage Pharma Group International's score of -0.35 indicating that Puma Biotechnology is being referred to more favorably in the media.

Company Overall Sentiment
Puma Biotechnology Neutral
Ascentage Pharma Group International Neutral

Ascentage Pharma Group International has a consensus price target of $46.43, indicating a potential upside of 150.97%. Given Ascentage Pharma Group International's stronger consensus rating and higher probable upside, analysts clearly believe Ascentage Pharma Group International is more favorable than Puma Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Puma Biotechnology
0 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
2.00
Ascentage Pharma Group International
0 Sell rating(s)
0 Hold rating(s)
8 Buy rating(s)
2 Strong Buy rating(s)
3.20

Puma Biotechnology has higher revenue and earnings than Ascentage Pharma Group International.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Puma Biotechnology$227.18M1.85$31.11M$0.4817.21
Ascentage Pharma Group International$82.10M21.04-$177.71MN/AN/A

61.3% of Puma Biotechnology shares are owned by institutional investors. 22.2% of Puma Biotechnology shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Summary

Puma Biotechnology beats Ascentage Pharma Group International on 9 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PBYI and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PBYI vs. The Competition

MetricPuma BiotechnologyMED IndustryMedical SectorNASDAQ Exchange
Market Cap$420.43M$3.78B$7.18B$12.47B
Dividend YieldN/A2.16%2.66%6.51%
P/E Ratio17.2121.6128.0224.70
Price / Sales1.85338.16537.0097.28
Price / Cash9.90147.1249.2657.09
Price / Book3.198.6610.966.46
Net Income$31.11M$23.81M$3.57B$337.01M
7 Day Performance1.85%3.39%2.12%1.69%
1 Month Performance17.50%10.81%5.25%3.81%
1 Year Performance132.68%62.61%33.29%23.90%

Puma Biotechnology Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PBYI
Puma Biotechnology
0.8168 of 5 stars
$8.26
flat
N/A+132.7%$420.43M$227.18M17.21200
ADMA
ADMA Biologics
4.4029 of 5 stars
$8.36
-0.2%
$19.67
+135.4%
-51.1%$1.93B$510.17M12.27530
CTMX
CytomX Therapeutics
1.9697 of 5 stars
$3.82
+2.0%
$12.10
+217.2%
+53.4%$647.57M$76.20MN/A170
TRDA
Entrada Therapeutics
2.7609 of 5 stars
$7.57
-1.8%
$17.50
+131.1%
+6.7%$294.45M$25.42MN/A110
MAZE
Maze Therapeutics
1.8216 of 5 stars
$29.48
+1.6%
$66.00
+123.9%
+171.8%$1.63B$20MN/A121

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This page (NASDAQ:PBYI) was last updated on 7/5/2026 by MarketBeat.com Staff.
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