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Stoke Therapeutics (STOK) Competitors

Stoke Therapeutics logo
$32.29 +0.89 (+2.83%)
As of 08/21/2026 04:00 PM Eastern

STOK vs. PCVX, APGE, IMVT, IBRX, and RYTM

Should you buy Stoke Therapeutics stock or one of its competitors? Stoke Therapeutics's main competitors and comparable companies include Vaxcyte (PCVX), Apogee Therapeutics (APGE), Immunovant (IMVT), ImmunityBio (IBRX), and Rhythm Pharmaceuticals (RYTM). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Stoke Therapeutics compare to Vaxcyte?

Vaxcyte (NASDAQ:PCVX) and Stoke Therapeutics (NASDAQ:STOK) are both mid-cap healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their risk, analyst recommendations, institutional ownership, valuation, dividends, earnings, media sentiment and profitability.

In the previous week, Stoke Therapeutics had 11 more articles in the media than Vaxcyte. MarketBeat recorded 14 mentions for Stoke Therapeutics and 3 mentions for Vaxcyte. Vaxcyte's average media sentiment score of 1.07 beat Stoke Therapeutics' score of 0.28 indicating that Vaxcyte is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vaxcyte
2 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Stoke Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

Vaxcyte has a net margin of 0.00% compared to Stoke Therapeutics' net margin of -753.60%. Vaxcyte's return on equity of -37.56% beat Stoke Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
VaxcyteN/A -37.56% -33.62%
Stoke Therapeutics -753.60%-59.36%-51.46%

96.8% of Vaxcyte shares are held by institutional investors. 3.3% of Vaxcyte shares are held by insiders. Comparatively, 9.6% of Stoke Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Stoke Therapeutics has higher revenue and earnings than Vaxcyte. Stoke Therapeutics is trading at a lower price-to-earnings ratio than Vaxcyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
VaxcyteN/AN/A-$766.63M-$7.63N/A
Stoke Therapeutics$184.42M11.30-$6.89M-$3.34N/A

Vaxcyte has a beta of 1.23, suggesting that its stock price is 23% more volatile than the broader market. Comparatively, Stoke Therapeutics has a beta of 1.2, suggesting that its stock price is 20% more volatile than the broader market.

Vaxcyte currently has a consensus target price of $86.00, suggesting a potential upside of 37.34%. Stoke Therapeutics has a consensus target price of $44.25, suggesting a potential upside of 37.04%. Given Vaxcyte's higher possible upside, research analysts plainly believe Vaxcyte is more favorable than Stoke Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vaxcyte
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50
Stoke Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82

Summary

Vaxcyte beats Stoke Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Stoke Therapeutics compare to Apogee Therapeutics?

Apogee Therapeutics (NASDAQ:APGE) and Stoke Therapeutics (NASDAQ:STOK) are both mid-cap healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their analyst recommendations, profitability, institutional ownership, valuation, dividends, risk, media sentiment and earnings.

In the previous week, Stoke Therapeutics had 9 more articles in the media than Apogee Therapeutics. MarketBeat recorded 14 mentions for Stoke Therapeutics and 5 mentions for Apogee Therapeutics. Apogee Therapeutics' average media sentiment score of 1.39 beat Stoke Therapeutics' score of 0.28 indicating that Apogee Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Apogee Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Stoke Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

79.0% of Apogee Therapeutics shares are held by institutional investors. 24.3% of Apogee Therapeutics shares are held by company insiders. Comparatively, 9.6% of Stoke Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Apogee Therapeutics currently has a consensus price target of $124.43, suggesting a potential downside of 7.66%. Stoke Therapeutics has a consensus price target of $44.25, suggesting a potential upside of 37.04%. Given Stoke Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Stoke Therapeutics is more favorable than Apogee Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Apogee Therapeutics
1 Sell rating(s)
15 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.20
Stoke Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82

Apogee Therapeutics has a net margin of 0.00% compared to Stoke Therapeutics' net margin of -753.60%. Apogee Therapeutics' return on equity of -29.88% beat Stoke Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Apogee TherapeuticsN/A -29.88% -28.08%
Stoke Therapeutics -753.60%-59.36%-51.46%

Apogee Therapeutics has a beta of 0.34, meaning that its share price is 66% less volatile than the broader market. Comparatively, Stoke Therapeutics has a beta of 1.2, meaning that its share price is 20% more volatile than the broader market.

Stoke Therapeutics has higher revenue and earnings than Apogee Therapeutics. Apogee Therapeutics is trading at a lower price-to-earnings ratio than Stoke Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Apogee TherapeuticsN/AN/A-$255.84M-$4.34N/A
Stoke Therapeutics$184.42M11.30-$6.89M-$3.34N/A

Summary

Stoke Therapeutics beats Apogee Therapeutics on 9 of the 16 factors compared between the two stocks.

How does Stoke Therapeutics compare to Immunovant?

Immunovant (NASDAQ:IMVT) and Stoke Therapeutics (NASDAQ:STOK) are both mid-cap healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their analyst recommendations, profitability, media sentiment, institutional ownership, risk, valuation, earnings and dividends.

47.1% of Immunovant shares are held by institutional investors. 1.9% of Immunovant shares are held by insiders. Comparatively, 9.6% of Stoke Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Immunovant has a net margin of 0.00% compared to Stoke Therapeutics' net margin of -753.60%. Stoke Therapeutics' return on equity of -59.36% beat Immunovant's return on equity.

Company Net Margins Return on Equity Return on Assets
ImmunovantN/A -69.59% -62.49%
Stoke Therapeutics -753.60%-59.36%-51.46%

Stoke Therapeutics has higher revenue and earnings than Immunovant. Immunovant is trading at a lower price-to-earnings ratio than Stoke Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ImmunovantN/AN/A-$505.61M-$2.82N/A
Stoke Therapeutics$184.42M11.30-$6.89M-$3.34N/A

Immunovant has a beta of 0.77, meaning that its share price is 23% less volatile than the broader market. Comparatively, Stoke Therapeutics has a beta of 1.2, meaning that its share price is 20% more volatile than the broader market.

Immunovant presently has a consensus target price of $44.00, suggesting a potential downside of 0.83%. Stoke Therapeutics has a consensus target price of $44.25, suggesting a potential upside of 37.04%. Given Stoke Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Stoke Therapeutics is more favorable than Immunovant.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Immunovant
1 Sell rating(s)
3 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.50
Stoke Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82

In the previous week, Stoke Therapeutics had 6 more articles in the media than Immunovant. MarketBeat recorded 14 mentions for Stoke Therapeutics and 8 mentions for Immunovant. Immunovant's average media sentiment score of 0.97 beat Stoke Therapeutics' score of 0.28 indicating that Immunovant is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Immunovant
4 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Stoke Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Stoke Therapeutics beats Immunovant on 11 of the 15 factors compared between the two stocks.

How does Stoke Therapeutics compare to ImmunityBio?

ImmunityBio (NASDAQ:IBRX) and Stoke Therapeutics (NASDAQ:STOK) are both mid-cap healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their dividends, risk, analyst recommendations, media sentiment, profitability, institutional ownership, earnings and valuation.

ImmunityBio has a net margin of -598.55% compared to Stoke Therapeutics' net margin of -753.60%. ImmunityBio's return on equity of 0.00% beat Stoke Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
ImmunityBio-598.55% N/A -51.65%
Stoke Therapeutics -753.60%-59.36%-51.46%

Stoke Therapeutics has higher revenue and earnings than ImmunityBio. Stoke Therapeutics is trading at a lower price-to-earnings ratio than ImmunityBio, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ImmunityBio$113.29M72.88-$351.40M-$0.97N/A
Stoke Therapeutics$184.42M11.30-$6.89M-$3.34N/A

ImmunityBio has a beta of 0.03, meaning that its stock price is 97% less volatile than the broader market. Comparatively, Stoke Therapeutics has a beta of 1.2, meaning that its stock price is 20% more volatile than the broader market.

ImmunityBio currently has a consensus price target of $14.20, indicating a potential upside of 82.28%. Stoke Therapeutics has a consensus price target of $44.25, indicating a potential upside of 37.04%. Given ImmunityBio's higher probable upside, equities analysts plainly believe ImmunityBio is more favorable than Stoke Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
ImmunityBio
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.71
Stoke Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82

8.6% of ImmunityBio shares are owned by institutional investors. 66.1% of ImmunityBio shares are owned by insiders. Comparatively, 9.6% of Stoke Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

In the previous week, Stoke Therapeutics had 12 more articles in the media than ImmunityBio. MarketBeat recorded 14 mentions for Stoke Therapeutics and 2 mentions for ImmunityBio. ImmunityBio's average media sentiment score of 1.13 beat Stoke Therapeutics' score of 0.28 indicating that ImmunityBio is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
ImmunityBio
1 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Stoke Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

ImmunityBio beats Stoke Therapeutics on 9 of the 16 factors compared between the two stocks.

How does Stoke Therapeutics compare to Rhythm Pharmaceuticals?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Stoke Therapeutics (NASDAQ:STOK) are both mid-cap healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their valuation, risk, dividends, analyst recommendations, earnings, media sentiment, institutional ownership and profitability.

Rhythm Pharmaceuticals has a beta of 1.92, indicating that its stock price is 92% more volatile than the broader market. Comparatively, Stoke Therapeutics has a beta of 1.2, indicating that its stock price is 20% more volatile than the broader market.

Rhythm Pharmaceuticals currently has a consensus price target of $142.44, indicating a potential upside of 29.49%. Stoke Therapeutics has a consensus price target of $44.25, indicating a potential upside of 37.04%. Given Stoke Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Stoke Therapeutics is more favorable than Rhythm Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.78
Stoke Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.82

Rhythm Pharmaceuticals has a net margin of -85.59% compared to Stoke Therapeutics' net margin of -753.60%. Stoke Therapeutics' return on equity of -59.36% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-85.59% -159.87% -44.00%
Stoke Therapeutics -753.60%-59.36%-51.46%

Stoke Therapeutics has lower revenue, but higher earnings than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Stoke Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$189.76M39.73-$196.54M-$3.11N/A
Stoke Therapeutics$184.42M11.30-$6.89M-$3.34N/A

In the previous week, Stoke Therapeutics had 4 more articles in the media than Rhythm Pharmaceuticals. MarketBeat recorded 14 mentions for Stoke Therapeutics and 10 mentions for Rhythm Pharmaceuticals. Rhythm Pharmaceuticals' average media sentiment score of 0.56 beat Stoke Therapeutics' score of 0.28 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Stoke Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Rhythm Pharmaceuticals beats Stoke Therapeutics on 8 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding STOK and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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STOK vs. The Competition

MetricStoke TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$2.08B$4.01B$7.37B$12.85B
Dividend YieldN/A3.64%2.53%11.08%
P/E Ratio-9.6711.62272.6024.24
Price / Sales11.301,338.17618.9699.81
Price / CashN/A105.1478.6253.99
Price / Book6.0216.8013.056.20
Net Income-$6.89M-$12.50M$3.47B$348.59M
7 Day Performance3.26%3.29%2.09%0.08%
1 Month Performance8.90%8.23%6.64%3.88%
1 Year Performance65.08%55.05%25.02%16.98%

Stoke Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
STOK
Stoke Therapeutics
2.4461 of 5 stars
$32.29
+2.8%
$44.25
+37.0%
+65.1%$2.08B$184.42MN/A100
PCVX
Vaxcyte
2.2586 of 5 stars
$58.29
+0.4%
$86.00
+47.5%
+93.9%$8.39BN/AN/A160
APGE
Apogee Therapeutics
1.3679 of 5 stars
$134.65
-0.1%
$121.25
-9.9%
+252.1%$8.34BN/AN/A91
IMVT
Immunovant
1.4326 of 5 stars
$39.89
-0.2%
$44.00
+10.3%
+191.1%$8.25BN/AN/A120
IBRX
ImmunityBio
2.6599 of 5 stars
$7.49
-2.0%
$14.20
+89.6%
+237.2%$8.10B$113.29MN/A590

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This page (NASDAQ:STOK) was last updated on 8/23/2026 by MarketBeat.com Staff.
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