NASDAQ:XENE Xenon Pharmaceuticals (XENE) Stock Price, News & Analysis $33.49 -0.84 (-2.45%) Closing price 10/16/2026 04:00 PM EasternExtended Trading$33.50 +0.01 (+0.02%) As of 10/16/2026 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Xenon Pharmaceuticals Stock (NASDAQ:XENE) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Xenon Pharmaceuticals alerts:Sign Up Key Stats Today's Range$33.38▼$34.3850-Day Range$33.49▼$65.2652-Week Range$33.38▼$72.66Volume1.08 million shsAverage Volume3.08 million shsMarket Capitalization$3.24 billionP/E RatioN/ADividend YieldN/APrice Target$70.14Consensus RatingModerate Buy Company Overview Xenon Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company focused on developing medicines for neurological and psychiatric disorders. The company uses research in ion channels and neuronal signaling to identify potential treatments for conditions with significant unmet medical needs. Xenon’s lead investigational medicine is azetukalner, also known as XEN1101, a selective potassium channel opener being evaluated for epilepsy and major depressive disorder. The company is also advancing additional programs aimed at genetically defined epilepsies and other disorders of the central nervous system. Its medicines remain in development and are subject to clinical and regulatory review. Founded in 1996 and headquartered in Vancouver, British Columbia, Xenon conducts research and clinical development activities in North America and works with external collaborators to advance its programs. The company’s operations are supported by a leadership team with experience in biotechnology, pharmaceutical development and neuroscience, including President and Chief Executive Officer Ian Mortimer.AI Generated. May Contain Errors. Read More Xenon Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks86th Percentile Overall ScoreXENE MarketRank™: 4.28942920296 of 5 starsXenon Pharmaceuticals scored higher than 86% of companies evaluated by MarketBeat, and ranked 63rd out of 887 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.4 / 5Analyst RatingModerate Buy Consensus RatingXenon Pharmaceuticals has received a consensus rating of Moderate Buy. The company's average rating score is 2.87, and is based on 1 strong buy rating, 12 buy ratings, 1 hold rating, and 1 sell rating.Upside PotentialXenon Pharmaceuticals has a consensus price target of $70.14, representing about 109.4% upside from its current price of $33.49.Amount of Analyst CoverageXenon Pharmaceuticals has been the subject of 10 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Xenon Pharmaceuticals' stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Xenon Pharmaceuticals are expected to decrease in the coming year, from ($4.70) to ($4.95) per share.Price to Book Value per Share RatioXenon Pharmaceuticals has a P/B Ratio of 4.45. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Xenon Pharmaceuticals' valuation and earnings. Short Interest4.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted6.44% of the float of Xenon Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverXenon Pharmaceuticals has a short interest ratio ("days to cover") of 1.58, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Xenon Pharmaceuticals has recently decreased by 6.26%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldXenon Pharmaceuticals does not currently pay a dividend.Dividend GrowthXenon Pharmaceuticals does not have a long track record of dividend growth. News and Social Media2.9 / 5News Sentiment0.64 News SentimentXenon Pharmaceuticals has a news sentiment score of 0.64. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.74 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 4 news articles for Xenon Pharmaceuticals this week, compared to 6 articles on an average week.Search Interest7 people have searched for XENE on MarketBeat in the last 30 days. MarketBeat Follows5 people have added Xenon Pharmaceuticals to their MarketBeat watchlist in the last 30 days. This is an increase of 400% compared to the previous 30 days. Company Ownership4.4 / 5Insider TradingAcquiring Shares Cluster Insider Buying2 insiders have purchased shares of Xenon Pharmaceuticals in the last three months. Multiple insiders buying is a strong bullish signal.Net Insider BuyingOver the last three months, insiders have purchased a net $614,753.00 in company stock, which represents 0.0190% of the company's market cap.Insider Buying vs. Insider SellingIn the past three months, Xenon Pharmaceuticals insiders have bought 57.64% more of their company's stock than they have sold. Specifically, they have bought $1,681,200.00 in company stock and sold $1,066,447.00 in company stock.Percentage Held by Insiders2.91% of the stock of Xenon Pharmaceuticals is held by insiders.Percentage Held by Institutions95.45% of the stock of Xenon Pharmaceuticals is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Xenon Pharmaceuticals' insider trading history. Receive XENE Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Xenon Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. 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XENE Stock News HeadlinesBank of America Securities Sticks to Their Buy Rating for Xenon (XENE)October 13, 2026 | theglobeandmail.comXenon Pharmaceuticals (NASDAQ:XENE) Downgraded by Wall Street Zen to "Strong Sell"October 11, 2026 | americanbankingnews.comReady to give options a try? Your first trade (Ticker included) -INSIDETired of trying tactic after tactic when it comes to options trades... only to be met with market noise and stinging losses? Dave Aquino is giving away the exact 11-hour options strategy he uses in volatile markets. You get the plain English blueprint behind the strategy and the very same "rinse and repeat" ticker he's traded nearly 900 times with a 95.3% success rate. It's so simple to understand, you could trade it tomorrow.October 17 at 1:00 AM | Base Camp Trading (Ad)Why Xenon Pharmaceuticals (XENE) Is Getting Attention NowOctober 9, 2026 | finance.yahoo.comXenon Pharmaceuticals (XENE) Stock May Still Look Above Fair Value On Its Research PipelineOctober 9, 2026 | uk.finance.yahoo.comWolf Popper LLP Continues Investigation on Behalf of Xenon Pharmaceuticals Inc. InvestorsOctober 7, 2026 | globenewswire.comXenon Pharmaceuticals (NASDAQ:XENE) Given "Buy" Rating at GuggenheimOctober 6, 2026 | americanbankingnews.comInsider Buying: Xenon Pharmaceuticals (NASDAQ:XENE) CFO Buys $559,800.00 in StockOctober 2, 2026 | insidertrades.comSee More Headlines XENE Stock Analysis - Frequently Asked Questions How have XENE shares performed this year? Xenon Pharmaceuticals' stock was trading at $44.82 on January 1st, 2026. Since then, XENE shares have decreased by 25.3% and is now trading at $33.49. How were Xenon Pharmaceuticals' earnings last quarter? Xenon Pharmaceuticals Inc. (NASDAQ:XENE) posted its earnings results on Thursday, August, 6th. The biopharmaceutical company reported ($1.11) earnings per share for the quarter, beating the consensus estimate of ($1.16) by $0.05. Read the conference call transcript. When did Xenon Pharmaceuticals IPO? Xenon Pharmaceuticals (XENE) raised $44 million in an initial public offering on Friday, October 17th 2014. The company issued 4,000,000 shares at a price of $10.00-$12.00 per share. Who are Xenon Pharmaceuticals' major shareholders? Xenon Pharmaceuticals' top institutional shareholders include Elmwood Wealth Management Inc. (0.01%), Wedmont Private Capital (0.01%) and GAMMA Investing LLC. Insiders that own company stock include Ian Mortimer, Gary Patou, Sherrington Robin, Andrea Difabio, Steven Gannon, Gillian Cannon, Christopher John Kenney and Sherry Aulin. View institutional ownership trends. How do I buy shares of Xenon Pharmaceuticals? Shares of XENE stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Xenon Pharmaceuticals own? Based on aggregate information from My MarketBeat watchlists, some other companies that Xenon Pharmaceuticals investors own include NVIDIA (NVDA), Tesla (TSLA), Advanced Micro Devices (AMD), Micron Technology (MU), Alibaba Group (BABA), Ford Motor (F) and AbbVie (ABBV). Company Calendar Last Earnings8/06/2026Today10/17/2026Next Earnings (Estimated)11/02/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Red Zone (4w+) 1-Year History Oct 25 Jan 26 Apr 26 Jul 26 Oct 26 For the last 4 weeks, XENE's financial health has been in the Red zone, according to TradeSmith. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:XENE CIK1582313 Webwww.xenon-pharma.com Phone(604) 484-3300Fax604-484-3450Employees364Year Founded1996Price Target and Rating Average Price Target for Xenon Pharmaceuticals$70.14 High Price Target$97.00 Low Price Target$46.00 Potential Upside/Downside+109.4%Consensus RatingModerate Buy Rating Score (0-4)2.87 Research Coverage15 Analysts Profitability EPS (Trailing Twelve Months)($4.74) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$345.91 million Net MarginsN/A Pretax MarginN/A Return on Equity-43.98% Return on Assets-41.72% Debt Debt-to-Equity RatioN/A Current Ratio21.01 Quick Ratio21.02 Sales & Book Value Annual Sales$7.50 million Price / Sales431.66 Cash FlowN/A Price / Cash FlowN/A Book Value$7.53 per share Price / Book4.45Miscellaneous Outstanding Shares96,670,000Free Float93,853,000Market Cap$3.24 billion OptionableOptionable Beta0.60 Social Links The Infrastructure's Backbone: 10 Stocks Powering the AI BuildoutThe AI boom extends far beyond the biggest tech names. Discover 10 companies supplying the memory, storage, networking, semiconductor manufacturing, and power infrastructure that make AI possible. Learn where the next wave of AI investment opportunities may emerge—and the key risks investors should watch as the global AI buildout accelerates.Get This Free Report This page (NASDAQ:XENE) was last updated on 10/16/2026 by MarketBeat.com Staff. From Our PartnersTicker Revealed: Pre-IPO Access to "Next Elon Musk" CompanyWe’ve found The Next Elon Musk… and what we believe to be the next Tesla. It’s already racked up $26 billi...Banyan Hill Publishing | SponsoredALERT: Drop these 5 stocks before the market opens tomorrow!The Wall Street Journal is already raising the alarm about a potential market crash, and Weiss Ratings researc...Weiss Ratings | SponsoredThe $15 Gold Fund That Pays Up to $1,152/MonthGold is hitting record highs, but most investors are leaving income on the table. 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