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Xenon Pharmaceuticals (XENE) Institutional Ownership

Xenon Pharmaceuticals logo
$54.17 0.00 (0.00%)
Closing price 05/22/2026 04:00 PM Eastern
Extended Trading
$54.14 -0.03 (-0.06%)
As of 05/22/2026 05:36 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Institutional Ownership Changes (13F Filings) for Xenon Pharmaceuticals (NASDAQ:XENE)

Current
Institutional Ownership
Percentage
95.45%
Number of
Institutional Buyers
(last 12 months)
162
Total
Institutional Inflows
(last 12 months)
$859.73M
Number of
Institutional Sellers
(last 12 months)
91
Total
Institutional Outflows
(last 12 months)
$603.02M
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XENE Institutional Buying and Selling by Quarter

Xenon Pharmaceuticals Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
5/19/2026 Bank of America Corp DE265,267$15.43M0.0%+19.8%0.274%
5/19/2026 Stempoint Capital LP140,755$8.19M1.6%-59.6%0.146%
5/19/2026 Janus Henderson Group PLC4,175,982$242.86M0.1%+2.3%4.320%
5/18/2026 ADAR1 Capital Management LLC228,899$13.31M0.8%+12.2%0.237%
5/18/2026 Amundi18,013$1.05M0.0%+290.8%0.019%
5/18/2026 California State Teachers Retirement System92,747$5.39M0.0%+64.0%0.096%
5/18/2026 Royal Bank of Canada90,387$5.26M0.0%+0.7%0.094%
5/18/2026 Redmile Group LLC262,674$15.27M1.0%+96.2%0.272%
5/18/2026 Rock Springs Capital Management LP763,020$44.37M2.6%-3.1%0.789%
5/18/2026 Eversept Partners LP129,574$7.54M0.4%-44.0%0.134%
5/16/2026 The Manufacturers Life Insurance Company 21,684$1.26M0.0%-33.5%0.022%
5/16/2026 Quantinno Capital Management LP55,444$3.22M0.0%+125.1%0.057%
5/16/2026 SummitTX Capital L.P.26,186$1.52M0.0%N/A0.027%
5/16/2026 Lazard Asset Management LLC50,755$2.95M0.0%-35.5%0.053%
5/16/2026 Castleark Management LLC64,563$3.75M0.1%N/A0.067%
5/16/2026 Orbimed Advisors LLC1,059,971$61.64M1.1%+137.0%1.096%
5/15/2026 Commodore Capital LP825,000$47.97M2.8%-54.2%0.853%
5/15/2026 Octagon Capital Advisors LP490,000$28.49M3.2%N/A0.507%
5/15/2026 Granahan Investment Management LLC104,478$6.08M0.3%+12.6%0.108%
5/15/2026 Affinity Asset Advisors LLC1,675,000$97.40M5.0%+34.0%1.733%
5/14/2026 Renaissance Technologies LLC300,500$17.47M0.0%N/A0.311%
5/14/2026 Siren L.L.C.1,318,564$76.67M2.1%+62.2%1.364%
5/14/2026 Atika Capital Management LLC59,900$3.48M0.4%-35.2%0.062%
5/14/2026 Sei Investments Co.114,381$6.65M0.0%+160.8%0.118%
5/13/2026 Cetera Investment Advisers3,624$211K0.0%N/A0.004%
5/13/2026 First Trust Advisors LP9,133$531K0.0%+43.6%0.009%
5/8/2026 PNC Financial Services Group Inc.8,097$471K0.0%+23.2%0.008%
5/7/2026 KBC Group NV129,010$7.50M0.0%+4,540.6%0.133%
5/7/2026 Swiss National Bank157,700$9.17M0.0%+38.3%0.163%
5/6/2026 Jennison Associates LLC1,318,814$76.69M0.1%+2.1%1.365%
5/6/2026 Assetmark Inc.20,272$1.18M0.0%-4.7%0.021%
5/6/2026 Allspring Global Investments Holdings LLC246,306$13.96M0.0%N/A0.255%
5/5/2026 Bank of New York Mellon Corp396,138$23.04M0.0%+2.3%0.410%
5/4/2026 Calamos Advisors LLC30,374$1.77M0.0%N/A0.031%
5/4/2026 Principal Financial Group Inc.6,244$363K0.0%+39.1%0.006%
5/4/2026 J. Safra Sarasin Holding AG9,071$527K0.0%-33.2%0.009%
5/4/2026 Teachers Retirement System of The State of Kentucky21,133$1.23M0.0%N/A0.022%
5/1/2026 Candriam S.C.A.476,494$27.71M0.1%+14.2%0.493%
4/30/2026 Hsbc Holdings PLC121,558$7.07M0.0%N/A0.126%
4/29/2026 Swedbank AB26,200$1.52M0.0%N/A0.027%
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4/27/2026 Y Intercept Hong Kong Ltd85,388$4.97M0.1%+17.0%0.088%
4/25/2026 Strs Ohio5,700$331K0.0%+338.5%0.006%
4/24/2026 Peregrine Capital Management LLC143,136$8.32M0.3%-18.1%0.172%
4/22/2026 Pictet Asset Management Holding SA679,709$39.23M0.0%+8.6%0.817%
4/16/2026 SG Americas Securities LLC9,119$530K0.0%+28.9%0.011%
3/17/2026 Rockefeller Capital Management L.P.1,100$49K0.0%+450.0%0.001%
3/9/2026 Corient Private Wealth LLC25,109$1.13M0.0%N/A0.030%
3/3/2026 Caitong International Asset Management Co. Ltd1,225$55K0.0%N/A0.001%
2/19/2026 T. Rowe Price Investment Management Inc.547,613$24.55M0.0%-8.6%0.709%
2/19/2026 Invesco Ltd.50,947$2.28M0.0%-9.1%0.066%
2/19/2026 Corient Private Wealth LLC25,109$1.13M0.0%N/A0.032%
2/18/2026 Mackenzie Financial Corp4,772$210K0.0%N/A0.006%
2/18/2026 ADAR1 Capital Management LLC203,969$9.14M0.7%+7.9%0.264%
2/18/2026 XTX Topco Ltd21,498$964K0.0%N/A0.028%
2/18/2026 Vestal Point Capital LP600,000$26.89M0.9%-45.5%0.776%
2/18/2026 Virtus Investment Advisers LLC6,037$271K0.1%+74.0%0.008%
2/18/2026 Squadron Capital Management LLC105,551$4.73M2.0%N/A0.137%
2/18/2026 Orbimed Advisors LLC447,200$20.04M0.4%+6.6%0.579%
2/18/2026 Oxford Asset Management LLP7,379$331K0.1%-66.7%0.010%
2/18/2026 Millennium Management LLC635,056$28.46M0.0%-56.2%0.822%
2/18/2026 Man Group plc114,826$5.15M0.0%+396.7%0.149%
2/18/2026 Janus Henderson Group PLC4,084,034$183.11M0.1%+3.6%5.285%
2/18/2026 Eversept Partners LP231,380$10.37M0.5%N/A0.299%
2/18/2026 Cinctive Capital Management LP23,317$1.05M0.1%+1.1%0.030%
2/18/2026 Commodore Capital LP1,800,000$80.68M5.4%-33.3%2.329%
2/18/2026 Balyasny Asset Management L.P.84,360$3.78M0.0%-73.8%0.109%
2/17/2026 ADAR1 Capital Management LLC203,969$9.14M0.7%+7.9%0.264%
2/17/2026 Braidwell LP1,825,076$81.80M2.6%-49.4%2.362%
2/17/2026 Abel Hall LLC6,757$303K0.1%N/A0.009%
2/17/2026 Lazard Asset Management LLC78,663$3.53M0.0%N/A0.102%
2/17/2026 MPM Bioimpact LLC485,620$21.77M2.5%-3.5%0.628%
2/17/2026 Jain Global LLC173,882$7.79M0.0%-31.1%0.225%
2/17/2026 Amundi4,609$207K0.0%N/A0.006%
2/17/2026 Jump Financial LLC30,987$1.39M0.0%+376.7%0.040%
2/17/2026Iron Triangle Partners LP233,688$10.47M1.2%N/A0.302%
2/17/2026 Price T Rowe Associates Inc. MD862,300$38.65M0.0%+1,968.3%1.116%
2/17/2026 T. Rowe Price Investment Management Inc.92,547$4.15M0.0%-84.6%0.120%
2/17/2026 Rock Springs Capital Management LP787,788$35.31M1.8%-7.5%1.019%
2/17/2026 Himension Capital Singapore PTE. LTD.11,279$506K0.0%N/A0.015%
2/17/2026 Adage Capital Partners GP L.L.C.685,100$30.71M0.0%-18.0%0.887%
2/17/2026 California State Teachers Retirement System56,564$2.54M0.0%-6.1%0.073%
2/17/2026 Russell Investments Group Ltd.86,220$3.86M0.0%+23.4%0.112%
2/17/2026 Granahan Investment Management LLC92,778$4.16M0.2%+6.1%0.120%
2/17/2026 State of Wisconsin Investment Board205,569$9.21M0.0%-1.3%0.266%
2/17/2026 Avoro Capital Advisors LLC5,424,444$243.12M2.3%+0.5%6.521%
2/17/2026 Royal Bank of Canada89,757$4.02M0.0%-25.5%0.116%
2/17/2026 Magnetar Financial LLC5,153$231K0.0%N/A0.007%
2/17/2026 Polar Capital Holdings Plc2,465,694$110.51M0.4%-3.2%3.191%
2/16/2026 Sofinnova Investments Inc.59,900$2.69M0.1%N/A0.078%
2/16/2026 Verition Fund Management LLC93,756$4.20M0.0%+64.1%0.121%
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2/16/2026 NEXTBio Capital Management LP183,704$8.23M4.8%N/A0.238%
2/16/2026 Nicholas Investment Partners LP242,989$10.89M0.8%+104.0%0.314%
2/16/2026 Entropy Technologies LP17,025$763K0.0%N/A0.022%
2/16/2026 Barclays PLC600,964$26.94M0.0%+439.9%0.778%
2/13/2026 Kestra Advisory Services LLC740$33K0.0%N/A0.001%
2/13/2026 Marshall Wace LLP162,551$7.29M0.0%-73.4%0.210%
2/13/2026 The Manufacturers Life Insurance Company 32,622$1.45M0.0%+36.3%0.042%
2/13/2026 Walleye Capital LLC19,587$878K0.0%N/A0.025%
2/13/2026 Affinity Asset Advisors LLC1,250,000$56.03M3.2%-10.7%1.617%
2/13/2026 Stifel Financial Corp17,548$787K0.0%-6.2%0.023%


XENE Institutional Ownership - Frequently Asked Questions

During the previous two years, 250 institutional investors and hedge funds held shares of Xenon Pharmaceuticals. The most heavily invested institutionals were FMR LLC ($294.99M), Avoro Capital Advisors LLC ($243.12M), Janus Henderson Group PLC ($242.86M), Driehaus Capital Management LLC ($153.82M), Capital International Investors ($153.06M), Wellington Management Group LLP ($144.94M), and Polar Capital Holdings Plc ($110.51M).Learn more on Xenon Pharmaceuticals' institutional investors.

95.45% of Xenon Pharmaceuticals' stock is owned by institutional investors. Learn more on XENE's institutional investor holdings.

Of the 216 institutional investors that purchased Xenon Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Janus Henderson Group PLC ($2.05M), Holocene Advisors LP ($1.98M), JPMorgan Chase & Co. ($1.67M), Vestal Point Capital LP ($1.49M), Wellington Management Group LLP ($1.46M), Braidwell LP ($1.25M), and Geode Capital Management LLC ($901.47K).

Institutional investors have bought a total of 21,011,350 shares in the last 24 months. This purchase volume represents approximately $859.73M in transactions.

Of the 91 institutional investors that sold Xenon Pharmaceuticals' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Commodore Capital LP ($2.20M), Braidwell LP ($1.78M), Vestal Point Capital LP ($1.40M), Marshall Wace LLP ($857.70K), Millennium Management LLC ($813.95K), Adage Capital Partners GP L.L.C. ($774.65K), and Pictet Asset Management Holding SA ($636.59K).

Institutional investors have sold a total of 14,158,293 shares in the last 24 months. This volume of shares sold represents approximately $603.02M in transactions.


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This page (NASDAQ:XENE) was last updated on 5/26/2026 by MarketBeat.com Staff.
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