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Xenon Pharmaceuticals (XENE) Competitors

Xenon Pharmaceuticals logo
$63.36 0.00 (0.00%)
Closing price 08/7/2026 04:00 PM Eastern
Extended Trading
$63.73 +0.37 (+0.58%)
As of 07:24 AM Eastern
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XENE vs. INCY, BNTX, UTHR, MRNA, and INSM

Should you buy Xenon Pharmaceuticals stock or one of its competitors? MarketBeat compares Xenon Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Xenon Pharmaceuticals include Incyte (INCY), BioNTech (BNTX), United Therapeutics (UTHR), Moderna (MRNA), and Insmed (INSM). These companies are all part of the "biotechnology" industry.

How does Xenon Pharmaceuticals compare to Incyte?

Xenon Pharmaceuticals (NASDAQ:XENE) and Incyte (NASDAQ:INCY) are both healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their analyst recommendations, institutional ownership, earnings, dividends, media sentiment, risk, valuation and profitability.

Incyte has higher revenue and earnings than Xenon Pharmaceuticals. Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than Incyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Xenon Pharmaceuticals$7.50M816.67-$345.91M-$4.74N/A
Incyte$5.14B4.75$1.29B$7.8515.36

Incyte has a net margin of 27.71% compared to Xenon Pharmaceuticals' net margin of 0.00%. Incyte's return on equity of 29.93% beat Xenon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Xenon PharmaceuticalsN/A -43.98% -41.72%
Incyte 27.71%29.93%22.88%

Xenon Pharmaceuticals currently has a consensus target price of $77.13, suggesting a potential upside of 21.74%. Incyte has a consensus target price of $120.40, suggesting a potential downside of 0.13%. Given Xenon Pharmaceuticals' stronger consensus rating and higher probable upside, equities analysts plainly believe Xenon Pharmaceuticals is more favorable than Incyte.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Xenon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
2 Strong Buy rating(s)
3.00
Incyte
0 Sell rating(s)
13 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.43

95.5% of Xenon Pharmaceuticals shares are owned by institutional investors. Comparatively, 97.0% of Incyte shares are owned by institutional investors. 2.9% of Xenon Pharmaceuticals shares are owned by company insiders. Comparatively, 16.2% of Incyte shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Xenon Pharmaceuticals has a beta of 0.62, suggesting that its share price is 38% less volatile than the broader market. Comparatively, Incyte has a beta of 0.76, suggesting that its share price is 24% less volatile than the broader market.

In the previous week, Xenon Pharmaceuticals had 3 more articles in the media than Incyte. MarketBeat recorded 15 mentions for Xenon Pharmaceuticals and 12 mentions for Incyte. Incyte's average media sentiment score of 0.94 beat Xenon Pharmaceuticals' score of 0.65 indicating that Incyte is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Xenon Pharmaceuticals
5 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Incyte
6 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Incyte beats Xenon Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

How does Xenon Pharmaceuticals compare to BioNTech?

BioNTech (NASDAQ:BNTX) and Xenon Pharmaceuticals (NASDAQ:XENE) are both healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their analyst recommendations, profitability, institutional ownership, risk, dividends, media sentiment, valuation and earnings.

Xenon Pharmaceuticals has lower revenue, but higher earnings than BioNTech. Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than BioNTech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioNTech$3.25B7.30-$1.29B-$7.83N/A
Xenon Pharmaceuticals$7.50M816.67-$345.91M-$4.74N/A

In the previous week, BioNTech had 9 more articles in the media than Xenon Pharmaceuticals. MarketBeat recorded 24 mentions for BioNTech and 15 mentions for Xenon Pharmaceuticals. Xenon Pharmaceuticals' average media sentiment score of 0.65 beat BioNTech's score of -0.11 indicating that Xenon Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BioNTech
4 Very Positive mention(s)
1 Positive mention(s)
8 Neutral mention(s)
8 Negative mention(s)
0 Very Negative mention(s)
Neutral
Xenon Pharmaceuticals
5 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

BioNTech has a beta of 1.27, meaning that its stock price is 27% more volatile than the broader market. Comparatively, Xenon Pharmaceuticals has a beta of 0.62, meaning that its stock price is 38% less volatile than the broader market.

Xenon Pharmaceuticals has a net margin of 0.00% compared to BioNTech's net margin of -63.54%. BioNTech's return on equity of -6.86% beat Xenon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
BioNTech-63.54% -6.86% -6.00%
Xenon Pharmaceuticals N/A -43.98%-41.72%

15.5% of BioNTech shares are held by institutional investors. Comparatively, 95.5% of Xenon Pharmaceuticals shares are held by institutional investors. 19.2% of BioNTech shares are held by company insiders. Comparatively, 2.9% of Xenon Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

BioNTech currently has a consensus price target of $127.81, suggesting a potential upside of 36.45%. Xenon Pharmaceuticals has a consensus price target of $77.13, suggesting a potential upside of 21.74%. Given BioNTech's higher possible upside, equities analysts plainly believe BioNTech is more favorable than Xenon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioNTech
1 Sell rating(s)
4 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.74
Xenon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
2 Strong Buy rating(s)
3.00

Summary

Xenon Pharmaceuticals beats BioNTech on 9 of the 17 factors compared between the two stocks.

How does Xenon Pharmaceuticals compare to United Therapeutics?

United Therapeutics (NASDAQ:UTHR) and Xenon Pharmaceuticals (NASDAQ:XENE) are both healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their analyst recommendations, earnings, valuation, dividends, media sentiment, risk, profitability and institutional ownership.

United Therapeutics has higher revenue and earnings than Xenon Pharmaceuticals. Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than United Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
United Therapeutics$3.18B7.26$1.33B$27.9519.28
Xenon Pharmaceuticals$7.50M816.67-$345.91M-$4.74N/A

In the previous week, United Therapeutics had 18 more articles in the media than Xenon Pharmaceuticals. MarketBeat recorded 33 mentions for United Therapeutics and 15 mentions for Xenon Pharmaceuticals. United Therapeutics' average media sentiment score of 0.68 beat Xenon Pharmaceuticals' score of 0.65 indicating that United Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
United Therapeutics
14 Very Positive mention(s)
7 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Xenon Pharmaceuticals
5 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

United Therapeutics has a net margin of 41.56% compared to Xenon Pharmaceuticals' net margin of 0.00%. United Therapeutics' return on equity of 20.18% beat Xenon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
United Therapeutics41.56% 20.18% 17.98%
Xenon Pharmaceuticals N/A -43.98%-41.72%

United Therapeutics has a beta of 0.59, indicating that its stock price is 41% less volatile than the broader market. Comparatively, Xenon Pharmaceuticals has a beta of 0.62, indicating that its stock price is 38% less volatile than the broader market.

United Therapeutics currently has a consensus price target of $646.00, indicating a potential upside of 19.89%. Xenon Pharmaceuticals has a consensus price target of $77.13, indicating a potential upside of 21.74%. Given Xenon Pharmaceuticals' stronger consensus rating and higher probable upside, analysts clearly believe Xenon Pharmaceuticals is more favorable than United Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
United Therapeutics
0 Sell rating(s)
2 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.85
Xenon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
2 Strong Buy rating(s)
3.00

94.1% of United Therapeutics shares are owned by institutional investors. Comparatively, 95.5% of Xenon Pharmaceuticals shares are owned by institutional investors. 8.6% of United Therapeutics shares are owned by company insiders. Comparatively, 2.9% of Xenon Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Summary

United Therapeutics beats Xenon Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does Xenon Pharmaceuticals compare to Moderna?

Moderna (NASDAQ:MRNA) and Xenon Pharmaceuticals (NASDAQ:XENE) are both healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their profitability, valuation, risk, dividends, earnings, analyst recommendations, institutional ownership and media sentiment.

Xenon Pharmaceuticals has lower revenue, but higher earnings than Moderna. Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than Moderna, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Moderna$1.94B12.15-$2.82B-$7.99N/A
Xenon Pharmaceuticals$7.50M816.67-$345.91M-$4.74N/A

In the previous week, Moderna had 41 more articles in the media than Xenon Pharmaceuticals. MarketBeat recorded 56 mentions for Moderna and 15 mentions for Xenon Pharmaceuticals. Xenon Pharmaceuticals' average media sentiment score of 0.65 beat Moderna's score of 0.49 indicating that Xenon Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Moderna
21 Very Positive mention(s)
8 Positive mention(s)
15 Neutral mention(s)
7 Negative mention(s)
0 Very Negative mention(s)
Neutral
Xenon Pharmaceuticals
5 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

75.3% of Moderna shares are held by institutional investors. Comparatively, 95.5% of Xenon Pharmaceuticals shares are held by institutional investors. 10.8% of Moderna shares are held by company insiders. Comparatively, 2.9% of Xenon Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Moderna has a beta of 0.91, meaning that its stock price is 9% less volatile than the broader market. Comparatively, Xenon Pharmaceuticals has a beta of 0.62, meaning that its stock price is 38% less volatile than the broader market.

Moderna presently has a consensus price target of $42.13, indicating a potential downside of 28.79%. Xenon Pharmaceuticals has a consensus price target of $77.13, indicating a potential upside of 21.74%. Given Xenon Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Xenon Pharmaceuticals is more favorable than Moderna.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Moderna
5 Sell rating(s)
9 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
1.88
Xenon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
2 Strong Buy rating(s)
3.00

Xenon Pharmaceuticals has a net margin of 0.00% compared to Moderna's net margin of -141.43%. Moderna's return on equity of -28.30% beat Xenon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Moderna-141.43% -28.30% -19.39%
Xenon Pharmaceuticals N/A -43.98%-41.72%

Summary

Xenon Pharmaceuticals beats Moderna on 10 of the 17 factors compared between the two stocks.

How does Xenon Pharmaceuticals compare to Insmed?

Xenon Pharmaceuticals (NASDAQ:XENE) and Insmed (NASDAQ:INSM) are both healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their analyst recommendations, earnings, dividends, institutional ownership, valuation, risk, media sentiment and profitability.

Xenon Pharmaceuticals presently has a consensus price target of $77.13, suggesting a potential upside of 21.74%. Insmed has a consensus price target of $205.26, suggesting a potential upside of 56.57%. Given Insmed's higher possible upside, analysts clearly believe Insmed is more favorable than Xenon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Xenon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
2 Strong Buy rating(s)
3.00
Insmed
1 Sell rating(s)
0 Hold rating(s)
23 Buy rating(s)
2 Strong Buy rating(s)
3.00

In the previous week, Insmed had 8 more articles in the media than Xenon Pharmaceuticals. MarketBeat recorded 23 mentions for Insmed and 15 mentions for Xenon Pharmaceuticals. Insmed's average media sentiment score of 0.70 beat Xenon Pharmaceuticals' score of 0.65 indicating that Insmed is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Xenon Pharmaceuticals
5 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Insmed
8 Very Positive mention(s)
4 Positive mention(s)
7 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Xenon Pharmaceuticals has a beta of 0.62, indicating that its share price is 38% less volatile than the broader market. Comparatively, Insmed has a beta of 0.81, indicating that its share price is 19% less volatile than the broader market.

95.5% of Xenon Pharmaceuticals shares are owned by institutional investors. 2.9% of Xenon Pharmaceuticals shares are owned by company insiders. Comparatively, 2.1% of Insmed shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Xenon Pharmaceuticals has higher earnings, but lower revenue than Insmed. Insmed is trading at a lower price-to-earnings ratio than Xenon Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Xenon Pharmaceuticals$7.50M816.67-$345.91M-$4.74N/A
Insmed$1.14B24.98-$1.28B-$4.11N/A

Xenon Pharmaceuticals has a net margin of 0.00% compared to Insmed's net margin of -76.94%. Xenon Pharmaceuticals' return on equity of -43.98% beat Insmed's return on equity.

Company Net Margins Return on Equity Return on Assets
Xenon PharmaceuticalsN/A -43.98% -41.72%
Insmed -76.94%-123.94%-44.30%

Summary

Xenon Pharmaceuticals beats Insmed on 8 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding XENE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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XENE vs. The Competition

MetricXenon PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$6.13B$3.69B$7.00B$12.99B
Dividend YieldN/A3.76%2.58%10.20%
P/E Ratio-13.379.02270.6125.05
Price / Sales816.671,287.31657.91107.93
Price / CashN/A44.9528.8937.44
Price / Book8.4117.6911.266.43
Net Income-$345.91M-$13.25M$3.45B$348.10M
7 Day Performance1.77%5.04%3.41%2.66%
1 Month Performance-8.07%-2.10%-0.71%-0.85%
1 Year Performance89.53%61.50%77.43%23.96%

Xenon Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
XENE
Xenon Pharmaceuticals
2.5807 of 5 stars
$63.36
flat
$77.13
+21.7%
+89.5%$6.13B$7.50MN/A210
INCY
Incyte
3.4043 of 5 stars
$118.43
-0.9%
$119.60
+1.0%
+53.8%$24.23B$5.14B15.092,844
BNTX
BioNTech
3.8565 of 5 stars
$92.25
+1.8%
$129.13
+40.0%
-16.1%$22.91B$3.25BN/A7,807
UTHR
United Therapeutics
4.4315 of 5 stars
$516.31
-0.3%
$648.33
+25.6%
+78.7%$21.98B$3.18B19.061,400
MRNA
Moderna
1.3628 of 5 stars
$55.14
+0.6%
$42.13
-23.6%
+126.5%$21.75B$1.94BN/A4,700

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This page (NASDAQ:XENE) was last updated on 8/10/2026 by MarketBeat.com Staff.
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