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Xenon Pharmaceuticals (XENE) Competitors

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$39.75 -17.60 (-30.69%)
Closing price 09/18/2026 04:00 PM Eastern
Extended Trading
$39.80 +0.05 (+0.11%)
As of 09/18/2026 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

XENE vs. UTHR, GMAB, ASND, BBIO, and SMMT

Should you buy Xenon Pharmaceuticals stock or one of its competitors? Xenon Pharmaceuticals's main competitors and comparable companies include United Therapeutics (UTHR), Genmab A/S (GMAB), Ascendis Pharma A/S (ASND), BridgeBio Pharma (BBIO), and Summit Therapeutics (SMMT). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Xenon Pharmaceuticals compare to United Therapeutics?

Xenon Pharmaceuticals (NASDAQ:XENE) and United Therapeutics (NASDAQ:UTHR) are both healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their risk, earnings, analyst recommendations, media sentiment, valuation, profitability, dividends and institutional ownership.

Xenon Pharmaceuticals has a beta of 0.61, suggesting that its stock price is 39% less volatile than the broader market. Comparatively, United Therapeutics has a beta of 0.56, suggesting that its stock price is 44% less volatile than the broader market.

United Therapeutics has higher revenue and earnings than Xenon Pharmaceuticals. Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than United Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Xenon Pharmaceuticals$7.50M512.35-$345.91M-$4.74N/A
United Therapeutics$3.18B6.67$1.33B$27.9517.70

United Therapeutics has a net margin of 41.56% compared to Xenon Pharmaceuticals' net margin of 0.00%. United Therapeutics' return on equity of 20.18% beat Xenon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Xenon PharmaceuticalsN/A -43.98% -41.72%
United Therapeutics 41.56%20.18%17.98%

In the previous week, Xenon Pharmaceuticals had 4 more articles in the media than United Therapeutics. MarketBeat recorded 27 mentions for Xenon Pharmaceuticals and 23 mentions for United Therapeutics. United Therapeutics' average media sentiment score of 0.65 beat Xenon Pharmaceuticals' score of -0.31 indicating that United Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Xenon Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
8 Neutral mention(s)
7 Negative mention(s)
3 Very Negative mention(s)
Neutral
United Therapeutics
13 Very Positive mention(s)
4 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

95.5% of Xenon Pharmaceuticals shares are held by institutional investors. Comparatively, 94.1% of United Therapeutics shares are held by institutional investors. 2.9% of Xenon Pharmaceuticals shares are held by insiders. Comparatively, 8.6% of United Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Xenon Pharmaceuticals currently has a consensus target price of $70.93, indicating a potential upside of 78.45%. United Therapeutics has a consensus target price of $646.00, indicating a potential upside of 30.60%. Given Xenon Pharmaceuticals' stronger consensus rating and higher possible upside, equities research analysts plainly believe Xenon Pharmaceuticals is more favorable than United Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Xenon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
2 Strong Buy rating(s)
2.94
United Therapeutics
0 Sell rating(s)
2 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.85

Summary

United Therapeutics beats Xenon Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Xenon Pharmaceuticals compare to Genmab A/S?

Genmab A/S (NASDAQ:GMAB) and Xenon Pharmaceuticals (NASDAQ:XENE) are both healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their valuation, risk, profitability, institutional ownership, analyst recommendations, dividends, media sentiment and earnings.

Genmab A/S has a beta of 0.84, indicating that its stock price is 16% less volatile than the broader market. Comparatively, Xenon Pharmaceuticals has a beta of 0.61, indicating that its stock price is 39% less volatile than the broader market.

Genmab A/S has higher revenue and earnings than Xenon Pharmaceuticals. Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than Genmab A/S, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Genmab A/S$3.72B5.83$963M$1.2727.35
Xenon Pharmaceuticals$7.50M512.35-$345.91M-$4.74N/A

In the previous week, Xenon Pharmaceuticals had 15 more articles in the media than Genmab A/S. MarketBeat recorded 27 mentions for Xenon Pharmaceuticals and 12 mentions for Genmab A/S. Genmab A/S's average media sentiment score of 0.64 beat Xenon Pharmaceuticals' score of -0.31 indicating that Genmab A/S is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Genmab A/S
2 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Xenon Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
8 Neutral mention(s)
7 Negative mention(s)
3 Very Negative mention(s)
Neutral

Genmab A/S has a net margin of 19.08% compared to Xenon Pharmaceuticals' net margin of 0.00%. Genmab A/S's return on equity of 14.89% beat Xenon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Genmab A/S19.08% 14.89% 7.73%
Xenon Pharmaceuticals N/A -43.98%-41.72%

7.1% of Genmab A/S shares are owned by institutional investors. Comparatively, 95.5% of Xenon Pharmaceuticals shares are owned by institutional investors. 1.5% of Genmab A/S shares are owned by insiders. Comparatively, 2.9% of Xenon Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Genmab A/S presently has a consensus price target of $39.50, suggesting a potential upside of 13.70%. Xenon Pharmaceuticals has a consensus price target of $70.93, suggesting a potential upside of 78.45%. Given Xenon Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Xenon Pharmaceuticals is more favorable than Genmab A/S.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Genmab A/S
0 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.85
Xenon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
2 Strong Buy rating(s)
2.94

Summary

Genmab A/S beats Xenon Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Xenon Pharmaceuticals compare to Ascendis Pharma A/S?

Ascendis Pharma A/S (NASDAQ:ASND) and Xenon Pharmaceuticals (NASDAQ:XENE) are both healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their analyst recommendations, media sentiment, dividends, profitability, valuation, earnings, risk and institutional ownership.

95.5% of Xenon Pharmaceuticals shares are held by institutional investors. 40.0% of Ascendis Pharma A/S shares are held by company insiders. Comparatively, 2.9% of Xenon Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Ascendis Pharma A/S presently has a consensus price target of $310.75, indicating a potential upside of 31.27%. Xenon Pharmaceuticals has a consensus price target of $70.93, indicating a potential upside of 78.45%. Given Xenon Pharmaceuticals' higher possible upside, analysts clearly believe Xenon Pharmaceuticals is more favorable than Ascendis Pharma A/S.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ascendis Pharma A/S
0 Sell rating(s)
1 Hold rating(s)
19 Buy rating(s)
1 Strong Buy rating(s)
3.00
Xenon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
2 Strong Buy rating(s)
2.94

Ascendis Pharma A/S has a beta of 0.35, indicating that its share price is 65% less volatile than the broader market. Comparatively, Xenon Pharmaceuticals has a beta of 0.61, indicating that its share price is 39% less volatile than the broader market.

Ascendis Pharma A/S has higher revenue and earnings than Xenon Pharmaceuticals. Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than Ascendis Pharma A/S, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ascendis Pharma A/S$814.57M18.13-$258M$12.8918.36
Xenon Pharmaceuticals$7.50M512.35-$345.91M-$4.74N/A

In the previous week, Xenon Pharmaceuticals had 4 more articles in the media than Ascendis Pharma A/S. MarketBeat recorded 27 mentions for Xenon Pharmaceuticals and 23 mentions for Ascendis Pharma A/S. Ascendis Pharma A/S's average media sentiment score of 0.68 beat Xenon Pharmaceuticals' score of -0.31 indicating that Ascendis Pharma A/S is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ascendis Pharma A/S
7 Very Positive mention(s)
7 Positive mention(s)
8 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Xenon Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
8 Neutral mention(s)
7 Negative mention(s)
3 Very Negative mention(s)
Neutral

Ascendis Pharma A/S has a net margin of 70.99% compared to Xenon Pharmaceuticals' net margin of 0.00%. Ascendis Pharma A/S's return on equity of 32.54% beat Xenon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ascendis Pharma A/S70.99% 32.54% 7.71%
Xenon Pharmaceuticals N/A -43.98%-41.72%

Summary

Ascendis Pharma A/S beats Xenon Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

How does Xenon Pharmaceuticals compare to BridgeBio Pharma?

BridgeBio Pharma (NASDAQ:BBIO) and Xenon Pharmaceuticals (NASDAQ:XENE) are both healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their institutional ownership, earnings, risk, dividends, media sentiment, valuation, analyst recommendations and profitability.

Xenon Pharmaceuticals has lower revenue, but higher earnings than BridgeBio Pharma. BridgeBio Pharma is trading at a lower price-to-earnings ratio than Xenon Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BridgeBio Pharma$502.08M25.94-$724.93M-$3.57N/A
Xenon Pharmaceuticals$7.50M512.35-$345.91M-$4.74N/A

BridgeBio Pharma currently has a consensus target price of $102.61, indicating a potential upside of 54.05%. Xenon Pharmaceuticals has a consensus target price of $70.93, indicating a potential upside of 78.45%. Given Xenon Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Xenon Pharmaceuticals is more favorable than BridgeBio Pharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BridgeBio Pharma
1 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
0 Strong Buy rating(s)
2.83
Xenon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
2 Strong Buy rating(s)
2.94

In the previous week, Xenon Pharmaceuticals had 19 more articles in the media than BridgeBio Pharma. MarketBeat recorded 27 mentions for Xenon Pharmaceuticals and 8 mentions for BridgeBio Pharma. BridgeBio Pharma's average media sentiment score of 0.87 beat Xenon Pharmaceuticals' score of -0.31 indicating that BridgeBio Pharma is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BridgeBio Pharma
4 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Xenon Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
8 Neutral mention(s)
7 Negative mention(s)
3 Very Negative mention(s)
Neutral

BridgeBio Pharma has a beta of 0.97, suggesting that its stock price is 3% less volatile than the broader market. Comparatively, Xenon Pharmaceuticals has a beta of 0.61, suggesting that its stock price is 39% less volatile than the broader market.

Xenon Pharmaceuticals has a net margin of 0.00% compared to BridgeBio Pharma's net margin of -97.03%. BridgeBio Pharma's return on equity of 0.00% beat Xenon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
BridgeBio Pharma-97.03% N/A -61.19%
Xenon Pharmaceuticals N/A -43.98%-41.72%

99.9% of BridgeBio Pharma shares are held by institutional investors. Comparatively, 95.5% of Xenon Pharmaceuticals shares are held by institutional investors. 14.2% of BridgeBio Pharma shares are held by insiders. Comparatively, 2.9% of Xenon Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Summary

Xenon Pharmaceuticals beats BridgeBio Pharma on 9 of the 17 factors compared between the two stocks.

How does Xenon Pharmaceuticals compare to Summit Therapeutics?

Xenon Pharmaceuticals (NASDAQ:XENE) and Summit Therapeutics (NASDAQ:SMMT) are both healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their analyst recommendations, dividends, valuation, profitability, risk, earnings, institutional ownership and media sentiment.

95.5% of Xenon Pharmaceuticals shares are owned by institutional investors. Comparatively, 4.6% of Summit Therapeutics shares are owned by institutional investors. 2.9% of Xenon Pharmaceuticals shares are owned by insiders. Comparatively, 83.5% of Summit Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

In the previous week, Xenon Pharmaceuticals had 20 more articles in the media than Summit Therapeutics. MarketBeat recorded 27 mentions for Xenon Pharmaceuticals and 7 mentions for Summit Therapeutics. Summit Therapeutics' average media sentiment score of 0.20 beat Xenon Pharmaceuticals' score of -0.31 indicating that Summit Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Xenon Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
8 Neutral mention(s)
7 Negative mention(s)
3 Very Negative mention(s)
Neutral
Summit Therapeutics
1 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Xenon Pharmaceuticals has higher revenue and earnings than Summit Therapeutics. Summit Therapeutics is trading at a lower price-to-earnings ratio than Xenon Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Xenon Pharmaceuticals$7.50M512.35-$345.91M-$4.74N/A
Summit TherapeuticsN/AN/A-$1.08B-$1.12N/A

Xenon Pharmaceuticals presently has a consensus target price of $70.93, indicating a potential upside of 78.45%. Summit Therapeutics has a consensus target price of $25.91, indicating a potential upside of 45.14%. Given Xenon Pharmaceuticals' stronger consensus rating and higher possible upside, research analysts clearly believe Xenon Pharmaceuticals is more favorable than Summit Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Xenon Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
2 Strong Buy rating(s)
2.94
Summit Therapeutics
1 Sell rating(s)
8 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.47

Xenon Pharmaceuticals' return on equity of -43.98% beat Summit Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Xenon PharmaceuticalsN/A -43.98% -41.72%
Summit Therapeutics N/A -168.94%-141.92%

Xenon Pharmaceuticals has a beta of 0.61, suggesting that its share price is 39% less volatile than the broader market. Comparatively, Summit Therapeutics has a beta of -1.24, suggesting that its share price is 224% less volatile than the broader market.

Summary

Xenon Pharmaceuticals beats Summit Therapeutics on 12 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding XENE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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XENE vs. The Competition

MetricXenon PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$5.54B$3.92B$7.24B$13.14B
Dividend YieldN/A3.65%2.57%12.30%
P/E Ratio-8.3914.30275.7925.40
Price / Sales512.351,415.50695.58114.44
Price / CashN/A110.7577.4251.66
Price / Book5.2815.4510.466.33
Net Income-$345.91M-$22.86M$3.49B$358.33M
7 Day Performance-32.23%-1.21%0.59%1.12%
1 Month Performance-36.22%-4.42%-2.01%-2.67%
1 Year Performance7.58%37.81%18.09%6.01%

Xenon Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
XENE
Xenon Pharmaceuticals
2.6549 of 5 stars
$39.75
-30.7%
$70.93
+78.4%
+5.3%$5.54B$7.50MN/A370
UTHR
United Therapeutics
4.2811 of 5 stars
$502.70
+1.1%
$646.00
+28.5%
+20.7%$21.32B$3.18B17.991,400
GMAB
Genmab A/S
4.2675 of 5 stars
$32.65
+0.6%
$39.50
+21.0%
+23.9%$20.25B$4.13B25.713,029
ASND
Ascendis Pharma A/S
4.7241 of 5 stars
$264.92
+0.5%
$310.80
+17.3%
+18.7%$16.44B$814.57M20.551,189
BBIO
BridgeBio Pharma
3.5816 of 5 stars
$72.38
-0.1%
$102.61
+41.8%
+24.9%$14.16B$713.07MN/A839

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This page (NASDAQ:XENE) was last updated on 9/19/2026 by MarketBeat.com Staff.
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