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NASDAQ:STOK

Stoke Therapeutics (STOK) Stock Price, News & Analysis

Stoke Therapeutics logo
$25.20 -0.09 (-0.36%)
As of 02:43 PM Eastern
This is a fair market value price provided by Massive. Learn more.

About Stoke Therapeutics Stock (NASDAQ:STOK)

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Key Stats

Today's Range
$24.92
▼
$25.52
50-Day Range
$25.29
▼
$33.46
52-Week Range
$20.32
▼
$40.22
Volume
351,704 shs
Average Volume
765,517 shs
Market Capitalization
$1.63 billion
P/E Ratio
N/A
Dividend Yield
N/A
Price Target
$44.25
Consensus Rating
Moderate Buy

Company Overview

Stoke Therapeutics, Inc. is a biotechnology company focused on developing RNA-based medicines for severe genetic diseases. The company’s approach is designed to increase the production of functional proteins by selectively targeting RNA splicing, a process that helps determine how genetic information is translated into proteins.

Stoke’s technology is based on its TANGO platform, which uses antisense oligonucleotides to promote the inclusion of productive genetic sequences in messenger RNA. Its lead investigational medicine, STK-001, is being developed for Dravet syndrome, a severe form of epilepsy commonly associated with mutations in the SCN1A gene. STK-001 is intended to increase production of functional Nav1.1 protein and is being evaluated in clinical studies.

Founded in 2014 and headquartered in Bedford, Massachusetts, Stoke serves the global rare-disease and genetic-medicine market through research and clinical development activities. The company’s leadership includes Edward M. Kaye, M.D., who serves as chief executive officer and has experience in the development of treatments for rare neurological disorders.

AI Generated. May Contain Errors.

Stoke Therapeutics Stock Analysis - MarketRank™

See Top-Rated MarketRank™ Stocks
57th Percentile Overall Score

STOK MarketRank™: 

Stoke Therapeutics scored higher than 57% of companies evaluated by MarketBeat, and ranked 415th out of 908 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

  • Consensus Rating

    Stoke Therapeutics has received a consensus rating of Moderate Buy. The company's average rating score is 2.82, and is based on no strong buy ratings, 10 buy ratings, no hold ratings, and 1 sell rating.

  • Upside Potential

    Stoke Therapeutics has a consensus price target of $44.25, representing about 74.4% upside from its current price of $25.37.

  • Amount of Analyst Coverage

    Stoke Therapeutics has been the subject of 7 research reports in the past 90 days, demonstrating strong analyst interest in this stock.

  • Read more about Stoke Therapeutics' stock forecast and price target.
  • Earnings Growth

    Earnings for Stoke Therapeutics are expected to grow in the coming year, from ($3.52) to ($3.44) per share.

  • Price to Earnings Ratio vs. the Market

    The P/E ratio of Stoke Therapeutics is -7.61, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Earnings Ratio vs. Sector

    The P/E ratio of Stoke Therapeutics is -7.61, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Book Value per Share Ratio

    Stoke Therapeutics has a P/B Ratio of 4.11. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

  • Read more about Stoke Therapeutics' valuation and earnings.
  • Percentage of Shares Shorted

    19.12% of the float of Stoke Therapeutics has been sold short.
  • Short Interest Ratio / Days to Cover

    Stoke Therapeutics has a short interest ratio ("days to cover") of 17.31, which indicates bearish sentiment.
  • Change versus previous month

    Short interest in Stoke Therapeutics has recently decreased by 0.47%, indicating that investor sentiment is improving.
  • Dividend Yield

    Stoke Therapeutics does not currently pay a dividend.

  • Dividend Growth

    Stoke Therapeutics does not have a long track record of dividend growth.

  • News Sentiment

    Stoke Therapeutics has a news sentiment score of 0.68. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Healthcare companies.
  • News Coverage This Week

    MarketBeat has tracked 7 news articles for Stoke Therapeutics this week, compared to 5 articles on an average week.
  • Search Interest

    Only 1 people have searched for STOK on MarketBeat in the last 30 days. This is a decrease of 0% compared to the previous 30 days.
  • Insider Buying vs. Insider Selling

    In the past three months, Stoke Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $1,025,302.00 in company stock.

  • Percentage Held by Insiders

    9.60% of the stock of Stoke Therapeutics is held by insiders.

  • Percentage Held by Institutions

    Stoke Therapeutics has minimal institutional ownership at this time.

  • Read more about Stoke Therapeutics' insider trading history.
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STOK Stock News Headlines

Stoke Therapeutics, Inc. Announces Board Changes
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See More Headlines

STOK Stock Analysis - Frequently Asked Questions

Stoke Therapeutics' stock was trading at $31.74 on January 1st, 2026. Since then, STOK stock has decreased by 20.1% and is now trading at $25.37.

Stoke Therapeutics, Inc. (NASDAQ:STOK) posted its quarterly earnings data on Monday, August, 3rd. The company reported ($0.93) earnings per share for the quarter, missing analysts' consensus estimates of ($0.80) by $0.14. The firm had revenue of $9.33 million for the quarter, compared to the consensus estimate of $4.89 million. Stoke Therapeutics had a negative net margin of 753.60% and a negative trailing twelve-month return on equity of 59.36%.
Read the conference call transcript
.

Stoke Therapeutics (STOK) raised $118 million in an initial public offering on Wednesday, June 19th 2019. The company issued 7,891,110 shares at a price of $14.00-$16.00 per share. J.P. Morgan, Cowen and Credit Suisse acted as the underwriters for the IPO and Canaccord Genuity was co-manager.

Top institutional shareholders of Stoke Therapeutics include BlackRock Inc. (9.11%), Wellington Management Group LLP (5.45%), Jupiter Topco LLC (2.81%) and Assenagon Asset Management S.A. (1.81%). Insiders that own company stock include Skorpios Trust, Adrian R Krainer, Edward M Md Kaye, Arthur Tzianabos, Jonathan Allan, Stephen J Tulipano, Barry Ticho, Jason Hoitt, Thomas Leggett and Arthur A Levin.
View institutional ownership trends
.

Shares of STOK stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

Based on aggregate information from My MarketBeat watchlists, some other companies that Stoke Therapeutics investors own include Enovix (ENVX), Rambus (RMBS), Compass Pathways (CMPS), Globant (GLOB), Ginkgo Bioworks (DNA), Toast (TOST) and Saia (SAIA).

Company Calendar

Last Earnings
8/03/2026
Today
9/25/2026
Next Earnings (Estimated)
11/03/2026
Fiscal Year End
12/31/2026

Industry, Sector and Symbol

Stock Exchange
NASDAQ
Industry
Biotechnology
Sub-Industry
Biotechnology
Current Symbol
NASDAQ:STOK
CIK
1623526
Fax
N/A
Employees
170
Year Founded
2014

Price Target and Rating

High Price Target
$60.00
Low Price Target
$35.00
Potential Upside/Downside
+75.6%
Consensus Rating
Moderate Buy
Rating Score (0-4)
2.82
Research Coverage
11 Analysts

Profitability

EPS (Trailing Twelve Months)
($3.34)
Trailing P/E Ratio
N/A
Forward P/E Ratio
N/A
P/E Growth
N/A
Net Income
-$6.89 million
Net Margins
-753.60%
Pretax Margin
-758.23%
Return on Equity
-59.36%
Return on Assets
-51.46%

Debt

Debt-to-Equity Ratio
N/A
Current Ratio
7.69
Quick Ratio
7.69

Sales & Book Value

Annual Sales
$184.42 million
Price / Sales
8.82
Cash Flow
N/A
Price / Cash Flow
N/A
Book Value
$6.17 per share
Price / Book
4.08

Miscellaneous

Outstanding Shares
64,530,000
Free Float
58,332,000
Market Cap
$1.63 billion
Optionable
Optionable
Beta
1.23

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This page (NASDAQ:STOK) was last updated on 9/25/2026 by MarketBeat.com Staff.
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