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Iovance Biotherapeutics (IOVA) Competitors

Iovance Biotherapeutics logo
$8.43 -0.27 (-3.10%)
Closing price 09/9/2026 04:00 PM Eastern
Extended Trading
$8.51 +0.08 (+0.89%)
As of 09/9/2026 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

IOVA vs. EXEL, BMRN, MDGL, HALO, and ARWR

Should you buy Iovance Biotherapeutics stock or one of its competitors? Iovance Biotherapeutics's main competitors and comparable companies include Exelixis (EXEL), BioMarin Pharmaceutical (BMRN), Madrigal Pharmaceuticals (MDGL), Halozyme Therapeutics (HALO), and Arrowhead Pharmaceuticals (ARWR). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Iovance Biotherapeutics compare to Exelixis?

Exelixis (NASDAQ:EXEL) and Iovance Biotherapeutics (NASDAQ:IOVA) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their risk, analyst recommendations, earnings, valuation, institutional ownership, dividends, media sentiment and profitability.

Exelixis presently has a consensus price target of $50.07, indicating a potential downside of 14.17%. Iovance Biotherapeutics has a consensus price target of $8.89, indicating a potential upside of 5.44%. Given Iovance Biotherapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Iovance Biotherapeutics is more favorable than Exelixis.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Exelixis
1 Sell rating(s)
12 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.35
Iovance Biotherapeutics
2 Sell rating(s)
2 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.45

Exelixis has a net margin of 35.33% compared to Iovance Biotherapeutics' net margin of -89.11%. Exelixis' return on equity of 42.17% beat Iovance Biotherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Exelixis35.33% 42.17% 31.76%
Iovance Biotherapeutics -89.11%-40.51%-31.65%

Exelixis has higher revenue and earnings than Iovance Biotherapeutics. Iovance Biotherapeutics is trading at a lower price-to-earnings ratio than Exelixis, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Exelixis$2.32B6.23$782.57M$3.1818.34
Iovance Biotherapeutics$263.50M14.49-$390.98M-$0.73N/A

Exelixis has a beta of 0.42, indicating that its share price is 58% less volatile than the broader market. Comparatively, Iovance Biotherapeutics has a beta of 0.83, indicating that its share price is 17% less volatile than the broader market.

In the previous week, Exelixis had 15 more articles in the media than Iovance Biotherapeutics. MarketBeat recorded 21 mentions for Exelixis and 6 mentions for Iovance Biotherapeutics. Iovance Biotherapeutics' average media sentiment score of 1.48 beat Exelixis' score of 1.00 indicating that Iovance Biotherapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Exelixis
8 Very Positive mention(s)
3 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Iovance Biotherapeutics
5 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

85.3% of Exelixis shares are held by institutional investors. Comparatively, 77.0% of Iovance Biotherapeutics shares are held by institutional investors. 2.6% of Exelixis shares are held by insiders. Comparatively, 7.8% of Iovance Biotherapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Summary

Exelixis beats Iovance Biotherapeutics on 10 of the 17 factors compared between the two stocks.

How does Iovance Biotherapeutics compare to BioMarin Pharmaceutical?

Iovance Biotherapeutics (NASDAQ:IOVA) and BioMarin Pharmaceutical (NASDAQ:BMRN) are both healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their analyst recommendations, dividends, valuation, risk, earnings, profitability, media sentiment and institutional ownership.

Iovance Biotherapeutics presently has a consensus target price of $8.89, suggesting a potential upside of 5.44%. BioMarin Pharmaceutical has a consensus target price of $89.17, suggesting a potential upside of 38.45%. Given BioMarin Pharmaceutical's stronger consensus rating and higher possible upside, analysts clearly believe BioMarin Pharmaceutical is more favorable than Iovance Biotherapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Iovance Biotherapeutics
2 Sell rating(s)
2 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.45
BioMarin Pharmaceutical
1 Sell rating(s)
6 Hold rating(s)
14 Buy rating(s)
2 Strong Buy rating(s)
2.74

Iovance Biotherapeutics has a beta of 0.83, meaning that its share price is 17% less volatile than the broader market. Comparatively, BioMarin Pharmaceutical has a beta of 0.24, meaning that its share price is 76% less volatile than the broader market.

BioMarin Pharmaceutical has a net margin of 2.14% compared to Iovance Biotherapeutics' net margin of -89.11%. BioMarin Pharmaceutical's return on equity of 5.32% beat Iovance Biotherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Iovance Biotherapeutics-89.11% -40.51% -31.65%
BioMarin Pharmaceutical 2.14%5.32%3.69%

BioMarin Pharmaceutical has higher revenue and earnings than Iovance Biotherapeutics. Iovance Biotherapeutics is trading at a lower price-to-earnings ratio than BioMarin Pharmaceutical, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Iovance Biotherapeutics$263.50M14.49-$390.98M-$0.73N/A
BioMarin Pharmaceutical$3.22B3.87$348.90M$0.37174.08

77.0% of Iovance Biotherapeutics shares are owned by institutional investors. Comparatively, 98.7% of BioMarin Pharmaceutical shares are owned by institutional investors. 7.8% of Iovance Biotherapeutics shares are owned by company insiders. Comparatively, 0.7% of BioMarin Pharmaceutical shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

In the previous week, BioMarin Pharmaceutical had 6 more articles in the media than Iovance Biotherapeutics. MarketBeat recorded 12 mentions for BioMarin Pharmaceutical and 6 mentions for Iovance Biotherapeutics. Iovance Biotherapeutics' average media sentiment score of 1.48 beat BioMarin Pharmaceutical's score of 0.65 indicating that Iovance Biotherapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Iovance Biotherapeutics
5 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
BioMarin Pharmaceutical
7 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

BioMarin Pharmaceutical beats Iovance Biotherapeutics on 13 of the 17 factors compared between the two stocks.

How does Iovance Biotherapeutics compare to Madrigal Pharmaceuticals?

Iovance Biotherapeutics (NASDAQ:IOVA) and Madrigal Pharmaceuticals (NASDAQ:MDGL) are both healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their valuation, analyst recommendations, media sentiment, dividends, earnings, institutional ownership, risk and profitability.

Madrigal Pharmaceuticals has higher revenue and earnings than Iovance Biotherapeutics. Madrigal Pharmaceuticals is trading at a lower price-to-earnings ratio than Iovance Biotherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Iovance Biotherapeutics$263.50M14.49-$390.98M-$0.73N/A
Madrigal Pharmaceuticals$958.40M13.18-$288.28M-$12.89N/A

Madrigal Pharmaceuticals has a net margin of -25.32% compared to Iovance Biotherapeutics' net margin of -89.11%. Iovance Biotherapeutics' return on equity of -40.51% beat Madrigal Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Iovance Biotherapeutics-89.11% -40.51% -31.65%
Madrigal Pharmaceuticals -25.32%-56.65%-25.53%

77.0% of Iovance Biotherapeutics shares are owned by institutional investors. Comparatively, 98.5% of Madrigal Pharmaceuticals shares are owned by institutional investors. 7.8% of Iovance Biotherapeutics shares are owned by insiders. Comparatively, 17.6% of Madrigal Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Iovance Biotherapeutics currently has a consensus target price of $8.89, indicating a potential upside of 5.44%. Madrigal Pharmaceuticals has a consensus target price of $699.64, indicating a potential upside of 27.99%. Given Madrigal Pharmaceuticals' stronger consensus rating and higher possible upside, analysts plainly believe Madrigal Pharmaceuticals is more favorable than Iovance Biotherapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Iovance Biotherapeutics
2 Sell rating(s)
2 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.45
Madrigal Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.78

In the previous week, Iovance Biotherapeutics had 3 more articles in the media than Madrigal Pharmaceuticals. MarketBeat recorded 6 mentions for Iovance Biotherapeutics and 3 mentions for Madrigal Pharmaceuticals. Iovance Biotherapeutics' average media sentiment score of 1.48 beat Madrigal Pharmaceuticals' score of 1.01 indicating that Iovance Biotherapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Iovance Biotherapeutics
5 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Madrigal Pharmaceuticals
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Iovance Biotherapeutics has a beta of 0.83, indicating that its share price is 17% less volatile than the broader market. Comparatively, Madrigal Pharmaceuticals has a beta of -0.98, indicating that its share price is 198% less volatile than the broader market.

Summary

Madrigal Pharmaceuticals beats Iovance Biotherapeutics on 9 of the 16 factors compared between the two stocks.

How does Iovance Biotherapeutics compare to Halozyme Therapeutics?

Halozyme Therapeutics (NASDAQ:HALO) and Iovance Biotherapeutics (NASDAQ:IOVA) are both healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their earnings, profitability, analyst recommendations, valuation, risk, dividends, media sentiment and institutional ownership.

97.8% of Halozyme Therapeutics shares are held by institutional investors. Comparatively, 77.0% of Iovance Biotherapeutics shares are held by institutional investors. 2.5% of Halozyme Therapeutics shares are held by company insiders. Comparatively, 7.8% of Iovance Biotherapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Halozyme Therapeutics has a net margin of 24.86% compared to Iovance Biotherapeutics' net margin of -89.11%. Halozyme Therapeutics' return on equity of 260.98% beat Iovance Biotherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Halozyme Therapeutics24.86% 260.98% 23.91%
Iovance Biotherapeutics -89.11%-40.51%-31.65%

Halozyme Therapeutics presently has a consensus price target of $91.20, suggesting a potential downside of 15.08%. Iovance Biotherapeutics has a consensus price target of $8.89, suggesting a potential upside of 5.44%. Given Iovance Biotherapeutics' higher possible upside, analysts plainly believe Iovance Biotherapeutics is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62
Iovance Biotherapeutics
2 Sell rating(s)
2 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.45

Halozyme Therapeutics has a beta of 0.88, suggesting that its stock price is 12% less volatile than the broader market. Comparatively, Iovance Biotherapeutics has a beta of 0.83, suggesting that its stock price is 17% less volatile than the broader market.

Halozyme Therapeutics has higher revenue and earnings than Iovance Biotherapeutics. Iovance Biotherapeutics is trading at a lower price-to-earnings ratio than Halozyme Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Halozyme Therapeutics$1.66B7.33$316.89M$3.3532.06
Iovance Biotherapeutics$263.50M14.49-$390.98M-$0.73N/A

In the previous week, Halozyme Therapeutics had 14 more articles in the media than Iovance Biotherapeutics. MarketBeat recorded 20 mentions for Halozyme Therapeutics and 6 mentions for Iovance Biotherapeutics. Iovance Biotherapeutics' average media sentiment score of 1.48 beat Halozyme Therapeutics' score of 0.74 indicating that Iovance Biotherapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Halozyme Therapeutics
7 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Iovance Biotherapeutics
5 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Halozyme Therapeutics beats Iovance Biotherapeutics on 12 of the 16 factors compared between the two stocks.

How does Iovance Biotherapeutics compare to Arrowhead Pharmaceuticals?

Arrowhead Pharmaceuticals (NASDAQ:ARWR) and Iovance Biotherapeutics (NASDAQ:IOVA) are both healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their institutional ownership, earnings, valuation, media sentiment, risk, profitability, analyst recommendations and dividends.

Arrowhead Pharmaceuticals presently has a consensus target price of $99.15, suggesting a potential upside of 20.00%. Iovance Biotherapeutics has a consensus target price of $8.89, suggesting a potential upside of 5.44%. Given Arrowhead Pharmaceuticals' stronger consensus rating and higher possible upside, research analysts clearly believe Arrowhead Pharmaceuticals is more favorable than Iovance Biotherapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Arrowhead Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.64
Iovance Biotherapeutics
2 Sell rating(s)
2 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.45

Arrowhead Pharmaceuticals has a net margin of -47.79% compared to Iovance Biotherapeutics' net margin of -89.11%. Iovance Biotherapeutics' return on equity of -40.51% beat Arrowhead Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Arrowhead Pharmaceuticals-47.79% -60.06% -17.37%
Iovance Biotherapeutics -89.11%-40.51%-31.65%

Arrowhead Pharmaceuticals has a beta of 1.28, indicating that its stock price is 28% more volatile than the broader market. Comparatively, Iovance Biotherapeutics has a beta of 0.83, indicating that its stock price is 17% less volatile than the broader market.

In the previous week, Arrowhead Pharmaceuticals had 6 more articles in the media than Iovance Biotherapeutics. MarketBeat recorded 12 mentions for Arrowhead Pharmaceuticals and 6 mentions for Iovance Biotherapeutics. Iovance Biotherapeutics' average media sentiment score of 1.48 beat Arrowhead Pharmaceuticals' score of 0.76 indicating that Iovance Biotherapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Arrowhead Pharmaceuticals
6 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Iovance Biotherapeutics
5 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

62.6% of Arrowhead Pharmaceuticals shares are owned by institutional investors. Comparatively, 77.0% of Iovance Biotherapeutics shares are owned by institutional investors. 3.6% of Arrowhead Pharmaceuticals shares are owned by company insiders. Comparatively, 7.8% of Iovance Biotherapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Arrowhead Pharmaceuticals has higher revenue and earnings than Iovance Biotherapeutics. Arrowhead Pharmaceuticals is trading at a lower price-to-earnings ratio than Iovance Biotherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Arrowhead Pharmaceuticals$829.45M14.03-$1.63M-$2.25N/A
Iovance Biotherapeutics$263.50M14.49-$390.98M-$0.73N/A

Summary

Arrowhead Pharmaceuticals beats Iovance Biotherapeutics on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding IOVA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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IOVA vs. The Competition

MetricIovance BiotherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$3.94B$3.90B$7.22B$12.88B
Dividend YieldN/A3.62%2.55%9.95%
P/E Ratio-11.5512.94271.7925.29
Price / Sales14.491,459.61709.75113.08
Price / CashN/A107.4077.5552.32
Price / Book4.7915.8110.636.26
Net Income-$390.98M-$22.81M$3.48B$357.86M
7 Day Performance-3.10%-0.13%-1.19%-0.56%
1 Month Performance31.72%4.54%1.99%-1.04%
1 Year Performance254.20%46.20%21.89%11.31%

Iovance Biotherapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
IOVA
Iovance Biotherapeutics
1.5214 of 5 stars
$8.43
-3.1%
$8.89
+5.4%
+255.7%$3.94B$263.50MN/A500
EXEL
Exelixis
3.0297 of 5 stars
$54.64
+0.3%
$50.07
-8.4%
+52.4%$13.54B$2.32B17.181,077
BMRN
BioMarin Pharmaceutical
4.8232 of 5 stars
$65.23
+0.9%
$88.92
+36.3%
+15.7%$12.63B$3.22B176.303,221
MDGL
Madrigal Pharmaceuticals
3.2171 of 5 stars
$540.03
+1.2%
$699.64
+29.6%
+21.8%$12.47B$958.40MN/A90
HALO
Halozyme Therapeutics
3.3643 of 5 stars
$106.49
+1.1%
$91.20
-14.4%
+41.2%$12.09B$1.40B31.79390

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This page (NASDAQ:IOVA) was last updated on 9/10/2026 by MarketBeat.com Staff.
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