Iovance Biotherapeutics (IOVA) Competitors $2.23 -0.11 (-4.70%) Closing price 04:00 PM EasternExtended Trading$2.24 +0.00 (+0.22%) As of 07:41 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock IOVA vs. APLS, NAMS, TWST, DNLI, KNSA, AGIO, VCEL, RXRX, CGON, and BEAMShould you be buying Iovance Biotherapeutics stock or one of its competitors? The main competitors of Iovance Biotherapeutics include Apellis Pharmaceuticals (APLS), NewAmsterdam Pharma (NAMS), Twist Bioscience (TWST), Denali Therapeutics (DNLI), Kiniksa Pharmaceuticals International (KNSA), Agios Pharmaceuticals (AGIO), Vericel (VCEL), Recursion Pharmaceuticals (RXRX), CG Oncology (CGON), and Beam Therapeutics (BEAM). These companies are all part of the "pharmaceutical products" industry. Iovance Biotherapeutics vs. Its Competitors Apellis Pharmaceuticals NewAmsterdam Pharma Twist Bioscience Denali Therapeutics Kiniksa Pharmaceuticals International Agios Pharmaceuticals Vericel Recursion Pharmaceuticals CG Oncology Beam Therapeutics Iovance Biotherapeutics (NASDAQ:IOVA) and Apellis Pharmaceuticals (NASDAQ:APLS) are both medical companies, but which is the superior stock? We will compare the two businesses based on the strength of their analyst recommendations, earnings, dividends, institutional ownership, valuation, risk, media sentiment and profitability. Which has better valuation & earnings, IOVA or APLS? Apellis Pharmaceuticals has higher revenue and earnings than Iovance Biotherapeutics. Apellis Pharmaceuticals is trading at a lower price-to-earnings ratio than Iovance Biotherapeutics, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioIovance Biotherapeutics$164.07M4.54-$372.18M-$1.24-1.80Apellis Pharmaceuticals$781.37M3.13-$197.88M-$1.79-10.88 Which has more volatility and risk, IOVA or APLS? Iovance Biotherapeutics has a beta of 0.85, indicating that its share price is 15% less volatile than the S&P 500. Comparatively, Apellis Pharmaceuticals has a beta of 0.67, indicating that its share price is 33% less volatile than the S&P 500. Do analysts recommend IOVA or APLS? Iovance Biotherapeutics presently has a consensus price target of $12.22, suggesting a potential upside of 448.08%. Apellis Pharmaceuticals has a consensus price target of $40.00, suggesting a potential upside of 105.44%. Given Iovance Biotherapeutics' higher possible upside, equities analysts clearly believe Iovance Biotherapeutics is more favorable than Apellis Pharmaceuticals.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Iovance Biotherapeutics 1 Sell rating(s) 6 Hold rating(s) 5 Buy rating(s) 0 Strong Buy rating(s) 2.33Apellis Pharmaceuticals 0 Sell rating(s) 9 Hold rating(s) 11 Buy rating(s) 1 Strong Buy rating(s) 2.62 Does the media favor IOVA or APLS? In the previous week, Iovance Biotherapeutics had 11 more articles in the media than Apellis Pharmaceuticals. MarketBeat recorded 34 mentions for Iovance Biotherapeutics and 23 mentions for Apellis Pharmaceuticals. Apellis Pharmaceuticals' average media sentiment score of 0.86 beat Iovance Biotherapeutics' score of 0.24 indicating that Apellis Pharmaceuticals is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Iovance Biotherapeutics 4 Very Positive mention(s) 5 Positive mention(s) 21 Neutral mention(s) 2 Negative mention(s) 0 Very Negative mention(s) Neutral Apellis Pharmaceuticals 6 Very Positive mention(s) 2 Positive mention(s) 4 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Do insiders and institutionals have more ownership in IOVA or APLS? 77.0% of Iovance Biotherapeutics shares are owned by institutional investors. Comparatively, 96.3% of Apellis Pharmaceuticals shares are owned by institutional investors. 10.3% of Iovance Biotherapeutics shares are owned by company insiders. Comparatively, 6.5% of Apellis Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth. Is IOVA or APLS more profitable? Apellis Pharmaceuticals has a net margin of -28.83% compared to Iovance Biotherapeutics' net margin of -176.49%. Iovance Biotherapeutics' return on equity of -49.71% beat Apellis Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Iovance Biotherapeutics-176.49% -49.71% -39.18% Apellis Pharmaceuticals -28.83%-99.19%-25.35% SummaryApellis Pharmaceuticals beats Iovance Biotherapeutics on 9 of the 17 factors compared between the two stocks. Get Iovance Biotherapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for IOVA and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding IOVA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart IOVA vs. The Competition Export to ExcelMetricIovance BiotherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$781.41M$2.96B$5.54B$9.41BDividend YieldN/A2.46%3.75%4.03%P/E Ratio-1.808.2821.0120.09Price / Sales4.54303.17433.8199.01Price / CashN/A42.5936.1658.27Price / Book0.967.678.125.65Net Income-$372.18M-$55.28M$3.25B$257.91M7 Day Performance19.25%2.50%0.97%2.09%1 Month Performance9.31%11.70%7.36%11.13%1 Year Performance-73.16%4.89%31.31%18.40% Iovance Biotherapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)IOVAIovance Biotherapeutics4.7457 of 5 stars$2.23-4.7%$12.22+448.1%-73.8%$781.41M$164.07M-1.80500Analyst DowngradeAnalyst RevisionGap UpAPLSApellis Pharmaceuticals4.3305 of 5 stars$17.41-4.7%$39.79+128.5%-49.3%$2.19B$781.37M-9.73770Trending NewsAnalyst ForecastInsider TradeAnalyst RevisionNAMSNewAmsterdam Pharma3.5952 of 5 stars$19.48-1.9%$42.89+120.2%+16.9%$2.19B$45.56M-10.364News CoverageAnalyst ForecastInsider TradeTWSTTwist Bioscience4.227 of 5 stars$35.54-6.9%$50.40+41.8%-36.2%$2.13B$312.97M-10.94990News CoverageDNLIDenali Therapeutics4.537 of 5 stars$14.27-2.9%$33.71+136.3%-36.9%$2.07B$330.53M-5.34430KNSAKiniksa Pharmaceuticals International3.3535 of 5 stars$28.12+0.9%$38.80+38.0%+34.7%$2.05B$481.17M-112.48220Upcoming EarningsInsider TradeAGIOAgios Pharmaceuticals4.409 of 5 stars$35.27-2.2%$58.60+66.1%-14.4%$2.04B$36.50M3.14390VCELVericel3.6832 of 5 stars$39.65-5.0%$61.14+54.2%-29.9%$2.00B$237.22M1,322.11300News CoveragePositive NewsRXRXRecursion Pharmaceuticals1.1335 of 5 stars$4.91-6.8%$7.00+42.6%-33.9%$2.00B$58.84M-2.77400Gap UpHigh Trading VolumeCGONCG Oncology2.531 of 5 stars$26.18-2.7%$58.67+124.1%-25.5%$2.00B$662K-17.3461News CoverageAnalyst ForecastBEAMBeam Therapeutics2.0658 of 5 stars$19.18-4.1%$48.75+154.2%-24.1%$1.93B$63.52M-4.16510Gap Up Related Companies and Tools Related Companies Apellis Pharmaceuticals Competitors NewAmsterdam Pharma Competitors Twist Bioscience Competitors Denali Therapeutics Competitors Kiniksa Pharmaceuticals International Competitors Agios Pharmaceuticals Competitors Vericel Competitors Recursion Pharmaceuticals Competitors CG Oncology Competitors Beam Therapeutics Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:IOVA) was last updated on 7/18/2025 by MarketBeat.com Staff From Our PartnersUtah’s New Oil FindThe Real Reason 218,000 Acres Just Vanished The government just quietly leased 218,000 acres in the middle ...Stansberry Research | SponsoredMarket Panic: Trump Just Dropped a Bomb on Your Stockstock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tarif...American Alternative | SponsoredCritical AI announcement set to ignite AI 2.0 I just put together an urgent new presentation that you need to see right away. 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