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Iovance Biotherapeutics (IOVA) Competitors

Iovance Biotherapeutics logo
$7.76 +0.13 (+1.70%)
Closing price 11/13/2026 04:00 PM Eastern
Extended Trading
$7.74 -0.01 (-0.19%)
As of 11/13/2026 07:58 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

IOVA vs. SMMT, KYMR, HALO, BMRN, and SYRE

Should you buy Iovance Biotherapeutics stock or one of its competitors? Iovance Biotherapeutics's main competitors and comparable companies include Summit Therapeutics (SMMT), Kymera Therapeutics (KYMR), Halozyme Therapeutics (HALO), BioMarin Pharmaceutical (BMRN), and Spyre Therapeutics (SYRE). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Iovance Biotherapeutics compare to Summit Therapeutics?

Summit Therapeutics (NASDAQ:SMMT) and Iovance Biotherapeutics (NASDAQ:IOVA) are both healthcare companies, but which is the better business? We will compare the two businesses based on the strength of their dividends, media sentiment, profitability, valuation, analyst recommendations, institutional ownership, earnings and risk.

Summit Therapeutics has a beta of -1.49, indicating that its share price is 249% less volatile than the broader market. Comparatively, Iovance Biotherapeutics has a beta of 0.88, indicating that its share price is 12% less volatile than the broader market.

4.6% of Summit Therapeutics shares are held by institutional investors. Comparatively, 77.0% of Iovance Biotherapeutics shares are held by institutional investors. 81.8% of Summit Therapeutics shares are held by insiders. Comparatively, 7.8% of Iovance Biotherapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Summit Therapeutics currently has a consensus target price of $28.61, suggesting a potential upside of 102.17%. Iovance Biotherapeutics has a consensus target price of $13.80, suggesting a potential upside of 77.84%. Given Summit Therapeutics' higher probable upside, analysts clearly believe Summit Therapeutics is more favorable than Iovance Biotherapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Summit Therapeutics
1 Sell rating(s)
7 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.58
Iovance Biotherapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.71

In the previous week, Iovance Biotherapeutics had 4 more articles in the media than Summit Therapeutics. MarketBeat recorded 12 mentions for Iovance Biotherapeutics and 8 mentions for Summit Therapeutics. Summit Therapeutics' average media sentiment score of 0.95 beat Iovance Biotherapeutics' score of 0.44 indicating that Summit Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Summit Therapeutics
4 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Iovance Biotherapeutics
2 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Summit Therapeutics has a net margin of 0.00% compared to Iovance Biotherapeutics' net margin of -58.20%. Iovance Biotherapeutics' return on equity of -29.71% beat Summit Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Summit TherapeuticsN/A -138.82% -117.11%
Iovance Biotherapeutics -58.20%-29.71%-23.55%

Iovance Biotherapeutics has higher revenue and earnings than Summit Therapeutics. Iovance Biotherapeutics is trading at a lower price-to-earnings ratio than Summit Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Summit TherapeuticsN/AN/A-$1.08B-$1.07N/A
Iovance Biotherapeutics$378.98M9.47-$390.98M-$0.53N/A

Summary

Iovance Biotherapeutics beats Summit Therapeutics on 9 of the 15 factors compared between the two stocks.

How does Iovance Biotherapeutics compare to Kymera Therapeutics?

Iovance Biotherapeutics (NASDAQ:IOVA) and Kymera Therapeutics (NASDAQ:KYMR) are both healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their institutional ownership, valuation, analyst recommendations, media sentiment, profitability, earnings, dividends and risk.

In the previous week, Iovance Biotherapeutics had 9 more articles in the media than Kymera Therapeutics. MarketBeat recorded 12 mentions for Iovance Biotherapeutics and 3 mentions for Kymera Therapeutics. Kymera Therapeutics' average media sentiment score of 0.87 beat Iovance Biotherapeutics' score of 0.44 indicating that Kymera Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Iovance Biotherapeutics
2 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Kymera Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

77.0% of Iovance Biotherapeutics shares are held by institutional investors. 7.8% of Iovance Biotherapeutics shares are held by company insiders. Comparatively, 16.0% of Kymera Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Iovance Biotherapeutics currently has a consensus target price of $13.80, suggesting a potential upside of 77.84%. Kymera Therapeutics has a consensus target price of $139.16, suggesting a potential upside of 9.09%. Given Iovance Biotherapeutics' higher possible upside, research analysts plainly believe Iovance Biotherapeutics is more favorable than Kymera Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Iovance Biotherapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.71
Kymera Therapeutics
1 Sell rating(s)
2 Hold rating(s)
23 Buy rating(s)
1 Strong Buy rating(s)
2.89

Iovance Biotherapeutics has a beta of 0.88, indicating that its stock price is 12% less volatile than the broader market. Comparatively, Kymera Therapeutics has a beta of 2.04, indicating that its stock price is 104% more volatile than the broader market.

Kymera Therapeutics has lower revenue, but higher earnings than Iovance Biotherapeutics. Kymera Therapeutics is trading at a lower price-to-earnings ratio than Iovance Biotherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Iovance Biotherapeutics$378.98M9.47-$390.98M-$0.53N/A
Kymera Therapeutics$39.21M277.75-$311.35M-$3.62N/A

Iovance Biotherapeutics has a net margin of -58.20% compared to Kymera Therapeutics' net margin of -285.33%. Kymera Therapeutics' return on equity of -22.39% beat Iovance Biotherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Iovance Biotherapeutics-58.20% -29.71% -23.55%
Kymera Therapeutics -285.33%-22.39%-20.48%

Summary

Kymera Therapeutics beats Iovance Biotherapeutics on 9 of the 16 factors compared between the two stocks.

How does Iovance Biotherapeutics compare to Halozyme Therapeutics?

Halozyme Therapeutics (NASDAQ:HALO) and Iovance Biotherapeutics (NASDAQ:IOVA) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their earnings, dividends, profitability, analyst recommendations, institutional ownership, media sentiment, risk and valuation.

97.8% of Halozyme Therapeutics shares are held by institutional investors. Comparatively, 77.0% of Iovance Biotherapeutics shares are held by institutional investors. 2.5% of Halozyme Therapeutics shares are held by company insiders. Comparatively, 7.8% of Iovance Biotherapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

In the previous week, Halozyme Therapeutics had 4 more articles in the media than Iovance Biotherapeutics. MarketBeat recorded 15 mentions for Halozyme Therapeutics and 11 mentions for Iovance Biotherapeutics. Iovance Biotherapeutics' average media sentiment score of 0.44 beat Halozyme Therapeutics' score of 0.24 indicating that Iovance Biotherapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Halozyme Therapeutics
3 Very Positive mention(s)
2 Positive mention(s)
4 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral
Iovance Biotherapeutics
2 Very Positive mention(s)
2 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Halozyme Therapeutics presently has a consensus target price of $108.18, indicating a potential upside of 7.89%. Iovance Biotherapeutics has a consensus target price of $13.80, indicating a potential upside of 77.84%. Given Iovance Biotherapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Iovance Biotherapeutics is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Halozyme Therapeutics
1 Sell rating(s)
5 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.46
Iovance Biotherapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.71

Halozyme Therapeutics has a beta of 0.92, indicating that its stock price is 8% less volatile than the broader market. Comparatively, Iovance Biotherapeutics has a beta of 0.88, indicating that its stock price is 12% less volatile than the broader market.

Halozyme Therapeutics has higher revenue and earnings than Iovance Biotherapeutics. Iovance Biotherapeutics is trading at a lower price-to-earnings ratio than Halozyme Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Halozyme Therapeutics$1.40B8.19$316.89M$3.9325.51
Iovance Biotherapeutics$378.98M9.47-$390.98M-$0.53N/A

Halozyme Therapeutics has a net margin of 26.93% compared to Iovance Biotherapeutics' net margin of -58.20%. Halozyme Therapeutics' return on equity of 751.81% beat Iovance Biotherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Halozyme Therapeutics26.93% 751.81% 23.84%
Iovance Biotherapeutics -58.20%-29.71%-23.55%

Summary

Halozyme Therapeutics beats Iovance Biotherapeutics on 10 of the 17 factors compared between the two stocks.

How does Iovance Biotherapeutics compare to BioMarin Pharmaceutical?

BioMarin Pharmaceutical (NASDAQ:BMRN) and Iovance Biotherapeutics (NASDAQ:IOVA) are both healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their profitability, valuation, analyst recommendations, dividends, media sentiment, institutional ownership, risk and earnings.

98.7% of BioMarin Pharmaceutical shares are held by institutional investors. Comparatively, 77.0% of Iovance Biotherapeutics shares are held by institutional investors. 0.7% of BioMarin Pharmaceutical shares are held by company insiders. Comparatively, 7.8% of Iovance Biotherapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

In the previous week, Iovance Biotherapeutics had 2 more articles in the media than BioMarin Pharmaceutical. MarketBeat recorded 12 mentions for Iovance Biotherapeutics and 10 mentions for BioMarin Pharmaceutical. Iovance Biotherapeutics' average media sentiment score of 0.44 beat BioMarin Pharmaceutical's score of 0.30 indicating that Iovance Biotherapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BioMarin Pharmaceutical
1 Very Positive mention(s)
3 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Iovance Biotherapeutics
2 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

BioMarin Pharmaceutical has a net margin of -0.52% compared to Iovance Biotherapeutics' net margin of -58.20%. BioMarin Pharmaceutical's return on equity of 5.58% beat Iovance Biotherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
BioMarin Pharmaceutical-0.52% 5.58% 3.51%
Iovance Biotherapeutics -58.20%-29.71%-23.55%

BioMarin Pharmaceutical has higher revenue and earnings than Iovance Biotherapeutics. BioMarin Pharmaceutical is trading at a lower price-to-earnings ratio than Iovance Biotherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioMarin Pharmaceutical$3.22B3.44$348.90M-$0.10N/A
Iovance Biotherapeutics$378.98M9.47-$390.98M-$0.53N/A

BioMarin Pharmaceutical has a beta of 0.21, indicating that its stock price is 79% less volatile than the broader market. Comparatively, Iovance Biotherapeutics has a beta of 0.88, indicating that its stock price is 12% less volatile than the broader market.

BioMarin Pharmaceutical presently has a consensus price target of $87.22, suggesting a potential upside of 52.40%. Iovance Biotherapeutics has a consensus price target of $13.80, suggesting a potential upside of 77.84%. Given Iovance Biotherapeutics' higher probable upside, analysts clearly believe Iovance Biotherapeutics is more favorable than BioMarin Pharmaceutical.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioMarin Pharmaceutical
1 Sell rating(s)
6 Hold rating(s)
15 Buy rating(s)
3 Strong Buy rating(s)
2.80
Iovance Biotherapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.71

Summary

BioMarin Pharmaceutical beats Iovance Biotherapeutics on 10 of the 17 factors compared between the two stocks.

How does Iovance Biotherapeutics compare to Spyre Therapeutics?

Iovance Biotherapeutics (NASDAQ:IOVA) and Spyre Therapeutics (NASDAQ:SYRE) are both mid-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their institutional ownership, profitability, analyst recommendations, media sentiment, earnings, risk, valuation and dividends.

Iovance Biotherapeutics has a beta of 0.88, indicating that its share price is 12% less volatile than the broader market. Comparatively, Spyre Therapeutics has a beta of 3.24, indicating that its share price is 224% more volatile than the broader market.

77.0% of Iovance Biotherapeutics shares are held by institutional investors. Comparatively, 80.4% of Spyre Therapeutics shares are held by institutional investors. 7.8% of Iovance Biotherapeutics shares are held by insiders. Comparatively, 15.7% of Spyre Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Spyre Therapeutics has lower revenue, but higher earnings than Iovance Biotherapeutics. Spyre Therapeutics is trading at a lower price-to-earnings ratio than Iovance Biotherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Iovance Biotherapeutics$378.98M9.47-$390.98M-$0.53N/A
Spyre Therapeutics$890K11,097.62-$155.20M-$2.74N/A

In the previous week, Iovance Biotherapeutics had 6 more articles in the media than Spyre Therapeutics. MarketBeat recorded 12 mentions for Iovance Biotherapeutics and 6 mentions for Spyre Therapeutics. Spyre Therapeutics' average media sentiment score of 0.57 beat Iovance Biotherapeutics' score of 0.44 indicating that Spyre Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Iovance Biotherapeutics
2 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Spyre Therapeutics
1 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Iovance Biotherapeutics presently has a consensus target price of $13.80, suggesting a potential upside of 77.84%. Spyre Therapeutics has a consensus target price of $110.53, suggesting a potential upside of 6.28%. Given Iovance Biotherapeutics' higher probable upside, analysts plainly believe Iovance Biotherapeutics is more favorable than Spyre Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Iovance Biotherapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.71
Spyre Therapeutics
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
2 Strong Buy rating(s)
2.94

Spyre Therapeutics has a net margin of 0.00% compared to Iovance Biotherapeutics' net margin of -58.20%. Iovance Biotherapeutics' return on equity of -29.71% beat Spyre Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Iovance Biotherapeutics-58.20% -29.71% -23.55%
Spyre Therapeutics N/A -35.97%-27.67%

Summary

Spyre Therapeutics beats Iovance Biotherapeutics on 10 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding IOVA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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IOVA vs. The Competition

MetricIovance BiotherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$3.53B$4.12B$7.84B$12.19B
Dividend YieldN/A3.62%2.46%4.53%
P/E Ratio-14.6425.7334.7128.44
Price / Sales9.4716.578.665.84
Price / CashN/A26.3721.9322.49
Price / Book4.414.004.353.76
Net Income-$390.98M-$22.78M$3.51B$390.55M
7 Day Performance-3.48%-2.85%-1.49%-0.33%
1 Month Performance-45.39%-3.75%-2.55%-4.82%
1 Year Performance214.17%-1.56%0.92%-5.83%

Iovance Biotherapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
IOVA
Iovance Biotherapeutics
2.7129 of 5 stars
$7.76
+1.7%
$13.80
+77.8%
+222.0%$3.53B$378.98MN/A975
SMMT
Summit Therapeutics
3.0799 of 5 stars
$17.84
+9.2%
$28.61
+60.4%
-22.5%$14.27BN/AN/A265
KYMR
Kymera Therapeutics
1.9827 of 5 stars
$138.86
+5.4%
$139.16
+0.2%
+100.5%$11.85B$102.24MN/A285
HALO
Halozyme Therapeutics
3.9767 of 5 stars
$102.92
-0.7%
$106.73
+3.7%
+40.8%$11.73B$1.40B26.19423
BMRN
BioMarin Pharmaceutical
4.2161 of 5 stars
$57.18
+2.1%
$87.91
+53.7%
+5.6%$11.08B$3.22BN/A3,221

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This page (NASDAQ:IOVA) was last updated on 11/14/2026 by MarketBeat.com Staff.
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