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Agios Pharmaceuticals (AGIO) Competitors

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$30.87 +0.66 (+2.18%)
As of 02:10 PM Eastern
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AGIO vs. IONS, ALKS, GRAL, IMVT, and IOVA

Should you buy Agios Pharmaceuticals stock or one of its competitors? Agios Pharmaceuticals's main competitors and comparable companies include Ionis Pharmaceuticals (IONS), Alkermes (ALKS), GRAIL (GRAL), Immunovant (IMVT), and Iovance Biotherapeutics (IOVA). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Agios Pharmaceuticals compare to Ionis Pharmaceuticals?

Ionis Pharmaceuticals (NASDAQ:IONS) and Agios Pharmaceuticals (NASDAQ:AGIO) are both healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their earnings, institutional ownership, profitability, media sentiment, analyst recommendations, risk, dividends and valuation.

In the previous week, Agios Pharmaceuticals had 2 more articles in the media than Ionis Pharmaceuticals. MarketBeat recorded 8 mentions for Agios Pharmaceuticals and 6 mentions for Ionis Pharmaceuticals. Ionis Pharmaceuticals' average media sentiment score of 0.47 beat Agios Pharmaceuticals' score of -0.01 indicating that Ionis Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ionis Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Agios Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

93.9% of Ionis Pharmaceuticals shares are held by institutional investors. 1.8% of Ionis Pharmaceuticals shares are held by company insiders. Comparatively, 5.4% of Agios Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Ionis Pharmaceuticals has a beta of 0.38, meaning that its stock price is 62% less volatile than the broader market. Comparatively, Agios Pharmaceuticals has a beta of 0.63, meaning that its stock price is 37% less volatile than the broader market.

Ionis Pharmaceuticals presently has a consensus target price of $89.20, suggesting a potential upside of 110.48%. Agios Pharmaceuticals has a consensus target price of $41.50, suggesting a potential upside of 37.37%. Given Ionis Pharmaceuticals' stronger consensus rating and higher probable upside, equities analysts plainly believe Ionis Pharmaceuticals is more favorable than Agios Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ionis Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.73
Agios Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.55

Ionis Pharmaceuticals has higher revenue and earnings than Agios Pharmaceuticals. Ionis Pharmaceuticals is trading at a lower price-to-earnings ratio than Agios Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ionis Pharmaceuticals$944M7.46-$381.39M-$3.46N/A
Agios Pharmaceuticals$54.03M33.38-$412.78M-$7.01N/A

Ionis Pharmaceuticals has a net margin of -64.76% compared to Agios Pharmaceuticals' net margin of -418.24%. Agios Pharmaceuticals' return on equity of -35.67% beat Ionis Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ionis Pharmaceuticals-64.76% -111.08% -17.41%
Agios Pharmaceuticals -418.24%-35.67%-33.06%

Summary

Ionis Pharmaceuticals beats Agios Pharmaceuticals on 10 of the 17 factors compared between the two stocks.

How does Agios Pharmaceuticals compare to Alkermes?

Agios Pharmaceuticals (NASDAQ:AGIO) and Alkermes (NASDAQ:ALKS) are both healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their earnings, media sentiment, risk, dividends, profitability, analyst recommendations, institutional ownership and valuation.

Agios Pharmaceuticals currently has a consensus target price of $41.50, indicating a potential upside of 37.37%. Alkermes has a consensus target price of $54.47, indicating a potential upside of 37.10%. Given Agios Pharmaceuticals' higher probable upside, research analysts clearly believe Agios Pharmaceuticals is more favorable than Alkermes.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Agios Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.55
Alkermes
1 Sell rating(s)
5 Hold rating(s)
11 Buy rating(s)
2 Strong Buy rating(s)
2.74

95.2% of Alkermes shares are owned by institutional investors. 5.4% of Agios Pharmaceuticals shares are owned by company insiders. Comparatively, 4.6% of Alkermes shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

In the previous week, Agios Pharmaceuticals had 4 more articles in the media than Alkermes. MarketBeat recorded 8 mentions for Agios Pharmaceuticals and 4 mentions for Alkermes. Alkermes' average media sentiment score of 0.35 beat Agios Pharmaceuticals' score of -0.01 indicating that Alkermes is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Agios Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Alkermes
0 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Agios Pharmaceuticals has a beta of 0.63, indicating that its share price is 37% less volatile than the broader market. Comparatively, Alkermes has a beta of 0.32, indicating that its share price is 68% less volatile than the broader market.

Alkermes has higher revenue and earnings than Agios Pharmaceuticals. Agios Pharmaceuticals is trading at a lower price-to-earnings ratio than Alkermes, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Agios Pharmaceuticals$54.03M33.38-$412.78M-$7.01N/A
Alkermes$1.48B4.52$241.66M$0.38104.55

Alkermes has a net margin of 3.96% compared to Agios Pharmaceuticals' net margin of -418.24%. Alkermes' return on equity of 4.15% beat Agios Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Agios Pharmaceuticals-418.24% -35.67% -33.06%
Alkermes 3.96%4.15%2.19%

Summary

Alkermes beats Agios Pharmaceuticals on 12 of the 17 factors compared between the two stocks.

How does Agios Pharmaceuticals compare to GRAIL?

GRAIL (NASDAQ:GRAL) and Agios Pharmaceuticals (NASDAQ:AGIO) are both healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their analyst recommendations, media sentiment, earnings, institutional ownership, profitability, valuation, dividends and risk.

GRAIL has higher revenue and earnings than Agios Pharmaceuticals. GRAIL is trading at a lower price-to-earnings ratio than Agios Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
GRAIL$147.17M42.60-$408.35M-$9.75N/A
Agios Pharmaceuticals$54.03M33.38-$412.78M-$7.01N/A

GRAIL currently has a consensus target price of $119.80, indicating a potential downside of 14.64%. Agios Pharmaceuticals has a consensus target price of $41.50, indicating a potential upside of 37.37%. Given Agios Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Agios Pharmaceuticals is more favorable than GRAIL.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
GRAIL
1 Sell rating(s)
6 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.33
Agios Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.55

GRAIL has a beta of 2.83, suggesting that its share price is 183% more volatile than the broader market. Comparatively, Agios Pharmaceuticals has a beta of 0.63, suggesting that its share price is 37% less volatile than the broader market.

In the previous week, GRAIL had 10 more articles in the media than Agios Pharmaceuticals. MarketBeat recorded 18 mentions for GRAIL and 8 mentions for Agios Pharmaceuticals. GRAIL's average media sentiment score of 0.46 beat Agios Pharmaceuticals' score of -0.01 indicating that GRAIL is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
GRAIL
5 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Agios Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

GRAIL has a net margin of -236.95% compared to Agios Pharmaceuticals' net margin of -418.24%. GRAIL's return on equity of -15.88% beat Agios Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
GRAIL-236.95% -15.88% -14.02%
Agios Pharmaceuticals -418.24%-35.67%-33.06%

Summary

GRAIL beats Agios Pharmaceuticals on 9 of the 13 factors compared between the two stocks.

How does Agios Pharmaceuticals compare to Immunovant?

Agios Pharmaceuticals (NASDAQ:AGIO) and Immunovant (NASDAQ:IMVT) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, dividends, earnings, valuation, institutional ownership, risk, profitability and analyst recommendations.

47.1% of Immunovant shares are owned by institutional investors. 5.4% of Agios Pharmaceuticals shares are owned by company insiders. Comparatively, 1.9% of Immunovant shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Agios Pharmaceuticals has higher revenue and earnings than Immunovant. Immunovant is trading at a lower price-to-earnings ratio than Agios Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Agios Pharmaceuticals$54.03M33.38-$412.78M-$7.01N/A
ImmunovantN/AN/A-$505.61M-$2.82N/A

In the previous week, Immunovant had 7 more articles in the media than Agios Pharmaceuticals. MarketBeat recorded 15 mentions for Immunovant and 8 mentions for Agios Pharmaceuticals. Immunovant's average media sentiment score of 0.45 beat Agios Pharmaceuticals' score of -0.01 indicating that Immunovant is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Agios Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Immunovant
4 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Agios Pharmaceuticals has a beta of 0.63, meaning that its stock price is 37% less volatile than the broader market. Comparatively, Immunovant has a beta of 0.84, meaning that its stock price is 16% less volatile than the broader market.

Agios Pharmaceuticals currently has a consensus target price of $41.50, indicating a potential upside of 37.37%. Immunovant has a consensus target price of $44.00, indicating a potential upside of 53.26%. Given Immunovant's stronger consensus rating and higher possible upside, analysts plainly believe Immunovant is more favorable than Agios Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Agios Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.55
Immunovant
1 Sell rating(s)
3 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.58

Immunovant has a net margin of 0.00% compared to Agios Pharmaceuticals' net margin of -418.24%. Agios Pharmaceuticals' return on equity of -35.67% beat Immunovant's return on equity.

Company Net Margins Return on Equity Return on Assets
Agios Pharmaceuticals-418.24% -35.67% -33.06%
Immunovant N/A -69.59%-62.49%

Summary

Immunovant beats Agios Pharmaceuticals on 9 of the 15 factors compared between the two stocks.

How does Agios Pharmaceuticals compare to Iovance Biotherapeutics?

Iovance Biotherapeutics (NASDAQ:IOVA) and Agios Pharmaceuticals (NASDAQ:AGIO) are both healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their profitability, valuation, risk, dividends, earnings, analyst recommendations, institutional ownership and media sentiment.

Iovance Biotherapeutics has a beta of 0.76, meaning that its stock price is 24% less volatile than the broader market. Comparatively, Agios Pharmaceuticals has a beta of 0.63, meaning that its stock price is 37% less volatile than the broader market.

Iovance Biotherapeutics has higher revenue and earnings than Agios Pharmaceuticals. Iovance Biotherapeutics is trading at a lower price-to-earnings ratio than Agios Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Iovance Biotherapeutics$263.50M24.93-$390.98M-$0.73N/A
Agios Pharmaceuticals$54.03M33.38-$412.78M-$7.01N/A

77.0% of Iovance Biotherapeutics shares are held by institutional investors. 7.8% of Iovance Biotherapeutics shares are held by company insiders. Comparatively, 5.4% of Agios Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

In the previous week, Agios Pharmaceuticals had 1 more articles in the media than Iovance Biotherapeutics. MarketBeat recorded 8 mentions for Agios Pharmaceuticals and 7 mentions for Iovance Biotherapeutics. Iovance Biotherapeutics' average media sentiment score of 0.56 beat Agios Pharmaceuticals' score of -0.01 indicating that Iovance Biotherapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Iovance Biotherapeutics
2 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Agios Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

Iovance Biotherapeutics presently has a consensus price target of $13.20, indicating a potential downside of 8.97%. Agios Pharmaceuticals has a consensus price target of $41.50, indicating a potential upside of 37.37%. Given Agios Pharmaceuticals' higher possible upside, analysts clearly believe Agios Pharmaceuticals is more favorable than Iovance Biotherapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Iovance Biotherapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62
Agios Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.55

Iovance Biotherapeutics has a net margin of -89.11% compared to Agios Pharmaceuticals' net margin of -418.24%. Agios Pharmaceuticals' return on equity of -35.67% beat Iovance Biotherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Iovance Biotherapeutics-89.11% -40.51% -31.65%
Agios Pharmaceuticals -418.24%-35.67%-33.06%

Summary

Iovance Biotherapeutics beats Agios Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding AGIO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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AGIO vs. The Competition

MetricAgios PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$1.83B$3.89B$7.27B$12.97B
Dividend YieldN/A3.65%2.51%22.89%
P/E Ratio-4.3712.96275.4025.37
Price / Sales33.851,150.23562.2978.82
Price / CashN/A118.5077.1653.04
Price / Book1.5016.5910.555.95
Net Income-$412.78M-$22.65M$3.50B$380.75M
7 Day Performance-3.64%-6.11%-3.92%-3.96%
1 Month Performance-7.79%-13.89%-8.30%-6.81%
1 Year Performance-23.87%6.58%2.35%-4.58%

Agios Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
AGIO
Agios Pharmaceuticals
3.0228 of 5 stars
$30.87
+2.2%
$41.50
+34.4%
-26.2%$1.85B$54.03MN/A540
IONS
Ionis Pharmaceuticals
3.2557 of 5 stars
$43.50
-0.1%
$89.20
+105.1%
-40.0%$7.24B$944MN/A1,402
ALKS
Alkermes
3.1987 of 5 stars
$42.76
+2.4%
$54.47
+27.4%
+23.5%$7.00B$1.48B112.532,050
GRAL
GRAIL
1.4329 of 5 stars
$154.08
+7.6%
$102.70
-33.3%
+99.2%$6.88B$165.26MN/A910
IMVT
Immunovant
2.4556 of 5 stars
$33.25
-1.1%
$44.00
+32.3%
+65.5%$6.87BN/AN/A315

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This page (NASDAQ:AGIO) was last updated on 10/14/2026 by MarketBeat.com Staff.
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