NASDAQ:AGIO Agios Pharmaceuticals (AGIO) Stock Price, News & Analysis $29.40 -1.02 (-3.35%) Closing price 05/29/2026 04:00 PM EasternExtended Trading$29.37 -0.03 (-0.12%) As of 05/29/2026 06:42 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Agios Pharmaceuticals Stock (NASDAQ:AGIO) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Agios Pharmaceuticals alerts:Sign Up Key Stats Today's Range$28.50▼$30.2850-Day Range$24.43▼$35.2052-Week Range$22.24▼$46.00Volume1.43 million shsAverage Volume794,834 shsMarket Capitalization$1.75 billionP/E RatioN/ADividend YieldN/APrice Target$41.44Consensus RatingHold Company Overview Agios Pharmaceuticals, Inc. is a biopharmaceutical company founded in 2008 as a spin-out from research at Dana-Farber Cancer Institute and the Broad Institute. Headquartered in Cambridge, Massachusetts, Agios focuses on understanding and targeting cellular metabolism to develop novel therapies for cancer and rare genetic diseases. The company’s scientific platform integrates genomic discovery, metabolic profiling and precision medicine approaches to identify and advance small-molecule candidates that correct or exploit metabolic dysfunction. Agios’s lead products are IDH (isocitrate dehydrogenase) inhibitors that target specific cancer mutations. Tibsovo (ivosidenib) is approved for treating relapsed or refractory acute myeloid leukemia (AML) with an IDH1 mutation and for certain advanced cholangiocarcinoma patients. Idhifa (enasidenib) addresses AML patients bearing an IDH2 mutation. These targeted therapies represent some of the first metabolism-based oncology treatments on the market. Beyond its approved products, Agios maintains a diverse pipeline in both oncology and rare genetic diseases. The company is developing mitapivat, a pyruvate kinase activator for chronic hemolytic anemias, in collaboration with Servier for ex-U.S. commercialization. Additional research programs leverage Agios’s expertise in metabolic targets to pursue next-generation candidates for hematologic malignancies and solid tumors. Agios markets its therapies directly in the United States and partners with global pharmaceutical companies for commercialization in Europe and other regions. Agios went public in 2013 and has maintained its headquarters and core research operations in Cambridge. Leadership is currently headed by President and CEO Jackie Fouse, with Catherine Shacklett serving as Chief Financial Officer. The company continues to expand its scientific capabilities and strategic collaborations as it advances its mission of translating metabolism research into life-changing treatments.AI Generated. May Contain Errors. Read More Agios Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks52nd Percentile Overall ScoreAGIO MarketRank™: Agios Pharmaceuticals scored higher than 52% of companies evaluated by MarketBeat, and ranked 547th out of 870 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.2 / 5Analyst RatingHold Consensus RatingAgios Pharmaceuticals has received a consensus rating of Hold. The company's average rating score is 2.45, and is based on no strong buy ratings, 6 buy ratings, 4 hold ratings, and 1 sell rating.Upside PotentialAgios Pharmaceuticals has a consensus price target of $41.44, representing about 41.0% upside from its current price of $29.40.Amount of Analyst CoverageAgios Pharmaceuticals has been the subject of 7 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Agios Pharmaceuticals' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Agios Pharmaceuticals are expected to grow in the coming year, from ($6.17) to ($4.79) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Agios Pharmaceuticals is -4.06, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Agios Pharmaceuticals is -4.06, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioAgios Pharmaceuticals has a P/B Ratio of 1.58. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.Read more about Agios Pharmaceuticals' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted13.24% of the float of Agios Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverAgios Pharmaceuticals has a short interest ratio ("days to cover") of 8.67.Change versus previous monthShort interest in Agios Pharmaceuticals has recently increased by 6.83%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldAgios Pharmaceuticals does not currently pay a dividend.Dividend GrowthAgios Pharmaceuticals does not have a long track record of dividend growth. News and Social Media2.2 / 5News Sentiment0.52 News SentimentAgios Pharmaceuticals has a news sentiment score of 0.52. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.82 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 10 news articles for Agios Pharmaceuticals this week, compared to 8 articles on an average week.Search InterestOnly 1 people have searched for AGIO on MarketBeat in the last 30 days. This is a decrease of -50% compared to the previous 30 days. Company Ownership0.9 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Agios Pharmaceuticals insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $520,405.00 in company stock.Percentage Held by Insiders5.40% of the stock of Agios Pharmaceuticals is held by insiders.Percentage Held by InstitutionsAgios Pharmaceuticals has minimal institutional ownership at this time.Read more about Agios Pharmaceuticals' insider trading history. 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Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. AGIO Stock News HeadlinesAgios Pharmaceuticals (NASDAQ:AGIO) Price Target Cut to $40.00 by Analysts at Bank of AmericaMay 30 at 3:37 AM | americanbankingnews.comAgios Pharmaceuticals, Inc.: Agios Provides Update on Phase 2b Trial of Tebapivat in Lower-Risk Myelodysplastic SyndromesMay 29 at 11:21 PM | finanznachrichten.deTrump’s New Dollar revealedThe last time something like this happened was 1974 - a secret deal that quietly determined the financial fate of an entire generation. According to Porter Stansberry, founder of one of the largest independent financial research firms in the world, it is happening again. Fortune calls it 'the biggest change to the world's relationship with the dollar' in a generation. Stansberry says Trump's money reset - enacted through executive orders and a treaty signed by 13 nations in December 2025 called Pax Silica - could determine whether you are enriched or quietly impoverished by the shift already underway.May 30 at 1:00 AM | Porter & Company (Ad)Agios: 'Sell' On Tebapivat Setback LR-MDS And Competitive PK Activator Drug ClassMay 29 at 4:11 PM | seekingalpha.comAgios scraps blood cancer drug program after study missMay 29 at 7:21 AM | reuters.comAgios Provides Update on Phase 2b Trial of Tebapivat in Lower-Risk Myelodysplastic SyndromesMay 29 at 7:00 AM | globenewswire.comAnalysts Offer Insights on Healthcare Companies: Clinuvel Pharmaceuticals (OtherCLVLF) and Agios Pharma (AGIO)May 27 at 7:41 AM | theglobeandmail.comAgios’ PYRUKYND® (mitapivat) Approved in the European Union for Adults with ThalassemiaMay 23, 2026 | finance.yahoo.comSee More Headlines AGIO Stock Analysis - Frequently Asked Questions How have AGIO shares performed this year? Agios Pharmaceuticals' stock was trading at $27.22 at the beginning of the year. Since then, AGIO stock has increased by 8.0% and is now trading at $29.40. How were Agios Pharmaceuticals' earnings last quarter? Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) released its quarterly earnings data on Wednesday, April, 29th. The biopharmaceutical company reported ($1.69) earnings per share (EPS) for the quarter, topping analysts' consensus estimates of ($1.81) by $0.12. Agios Pharmaceuticals's quarterly revenue was up 137.7% on a year-over-year basis. Read the conference call transcript. When did Agios Pharmaceuticals IPO? Agios Pharmaceuticals (AGIO) raised $88 million in an initial public offering on Wednesday, July 24th 2013. The company issued 5,888,888 shares at $14.00-$16.00 per share. Who are Agios Pharmaceuticals' major shareholders? Top institutional shareholders of Agios Pharmaceuticals include Dimensional Fund Advisors LP (1.94%), Bank of America Corp DE (0.85%), Arrowstreet Capital Limited Partnership (0.42%) and Eversept Partners LP (0.34%). Insiders that own company stock include Jacqualyn A Fouse, Brian Goff, Sarah Gheuens, Cecilia Jones, James William Burns, Tsveta Milanova, David Scadden, Kaye I Foster-Cheek, Krishnan Viswanadhan and Theodore James Jr Washburn. View institutional ownership trends. How do I buy shares of Agios Pharmaceuticals? Shares of AGIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Agios Pharmaceuticals own? Based on aggregate information from My MarketBeat watchlists, some other companies that Agios Pharmaceuticals investors own include Waste Connections (WCN), American Water Works (AWK), DiamondRock Hospitality (DRH), The RMR Group (RMR), AUO (AUOTY), iShares Micro-Cap ETF (IWC) and Voyager Therapeutics (VYGR). Company Calendar Last Earnings4/29/2026Today5/30/2026Next Earnings (Estimated)7/30/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (1w+) 1-Year History May 25 Aug 25 Nov 25 Feb 26 May 26 For the last 10 days, AGIO's financial health has been in the Green zone, according to TradeSmith. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:AGIO CIK1439222 Webwww.agios.com Phone(617) 649-8600FaxN/AEmployees390Year Founded2008Price Target and Rating Average Price Target for Agios Pharmaceuticals$41.44 High Price Target$65.00 Low Price Target$28.00 Potential Upside/Downside+41.0%Consensus RatingHold Rating Score (0-4)2.45 Research Coverage11 Analysts Profitability EPS (Trailing Twelve Months)($7.25) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$412.78 million Net Margins-639.84% Pretax Margin-641.38% Return on Equity-34.11% Return on Assets-31.66% Debt Debt-to-Equity RatioN/A Current Ratio14.19 Quick Ratio13.59 Sales & Book Value Annual Sales$54.03 million Price / Sales32.36 Cash FlowN/A Price / Cash FlowN/A Book Value$18.65 per share Price / Book1.58Miscellaneous Outstanding Shares59,470,000Free Float56,261,000Market Cap$1.75 billion OptionableOptionable Beta0.58 Social Links The 7 Hottest IPOs On Wall Street’s 2026 WatchlistMarketBeat just released its list of the 7 hottest IPOs expected to hit Wall Street in 2026. 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