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Denali Therapeutics (DNLI) Competitors

Denali Therapeutics logo
$19.34 -0.01 (-0.05%)
As of 01:21 PM Eastern

DNLI vs. BEAM, RDY, ELAN, ARWR, and ABVX

Should you buy Denali Therapeutics stock or one of its competitors? MarketBeat compares Denali Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Denali Therapeutics include Beam Therapeutics (BEAM), Dr. Reddy's Laboratories (RDY), Elanco Animal Health (ELAN), Arrowhead Pharmaceuticals (ARWR), and Abivax (ABVX). These companies are all part of the "pharmaceutical products" industry.

How does Denali Therapeutics compare to Beam Therapeutics?

Beam Therapeutics (NASDAQ:BEAM) and Denali Therapeutics (NASDAQ:DNLI) are both mid-cap medical companies, but which is the superior stock? We will compare the two businesses based on the strength of their analyst recommendations, valuation, media sentiment, profitability, institutional ownership, risk, dividends and earnings.

In the previous week, Beam Therapeutics had 3 more articles in the media than Denali Therapeutics. MarketBeat recorded 5 mentions for Beam Therapeutics and 2 mentions for Denali Therapeutics. Denali Therapeutics' average media sentiment score of 1.26 beat Beam Therapeutics' score of 0.96 indicating that Denali Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Beam Therapeutics
1 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Denali Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

99.7% of Beam Therapeutics shares are held by institutional investors. Comparatively, 92.9% of Denali Therapeutics shares are held by institutional investors. 3.8% of Beam Therapeutics shares are held by insiders. Comparatively, 12.5% of Denali Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Beam Therapeutics presently has a consensus target price of $46.83, suggesting a potential upside of 60.94%. Denali Therapeutics has a consensus target price of $34.25, suggesting a potential upside of 77.19%. Given Denali Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Denali Therapeutics is more favorable than Beam Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Beam Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.71
Denali Therapeutics
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.87

Denali Therapeutics has a net margin of 0.00% compared to Beam Therapeutics' net margin of -39.66%. Beam Therapeutics' return on equity of -29.00% beat Denali Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Beam Therapeutics-39.66% -29.00% -22.61%
Denali Therapeutics N/A -52.20%-43.86%

Beam Therapeutics has a beta of 2.25, suggesting that its stock price is 125% more volatile than the broader market. Comparatively, Denali Therapeutics has a beta of 1.03, suggesting that its stock price is 3% more volatile than the broader market.

Beam Therapeutics has higher earnings, but lower revenue than Denali Therapeutics. Beam Therapeutics is trading at a lower price-to-earnings ratio than Denali Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Beam Therapeutics$139.74M21.42-$79.99M-$0.68N/A
Denali Therapeutics$330.53M9.28-$512.54M-$2.88N/A

Summary

Beam Therapeutics and Denali Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Denali Therapeutics compare to Dr. Reddy's Laboratories?

Denali Therapeutics (NASDAQ:DNLI) and Dr. Reddy's Laboratories (NYSE:RDY) are both medical companies, but which is the superior investment? We will compare the two companies based on the strength of their dividends, institutional ownership, valuation, media sentiment, analyst recommendations, risk, profitability and earnings.

In the previous week, Dr. Reddy's Laboratories had 7 more articles in the media than Denali Therapeutics. MarketBeat recorded 9 mentions for Dr. Reddy's Laboratories and 2 mentions for Denali Therapeutics. Denali Therapeutics' average media sentiment score of 1.26 beat Dr. Reddy's Laboratories' score of 0.00 indicating that Denali Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Denali Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Dr. Reddy's Laboratories
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Dr. Reddy's Laboratories has higher revenue and earnings than Denali Therapeutics. Denali Therapeutics is trading at a lower price-to-earnings ratio than Dr. Reddy's Laboratories, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Denali Therapeutics$330.53M9.28-$512.54M-$2.88N/A
Dr. Reddy's Laboratories$335.93B0.03$484.20M$0.5822.43

Denali Therapeutics has a beta of 1.03, indicating that its stock price is 3% more volatile than the broader market. Comparatively, Dr. Reddy's Laboratories has a beta of 0.27, indicating that its stock price is 73% less volatile than the broader market.

92.9% of Denali Therapeutics shares are owned by institutional investors. Comparatively, 3.8% of Dr. Reddy's Laboratories shares are owned by institutional investors. 12.5% of Denali Therapeutics shares are owned by insiders. Comparatively, 2.0% of Dr. Reddy's Laboratories shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Denali Therapeutics currently has a consensus target price of $34.25, indicating a potential upside of 77.19%. Dr. Reddy's Laboratories has a consensus target price of $16.90, indicating a potential upside of 29.90%. Given Denali Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Denali Therapeutics is more favorable than Dr. Reddy's Laboratories.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Denali Therapeutics
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.87
Dr. Reddy's Laboratories
1 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Dr. Reddy's Laboratories has a net margin of 12.90% compared to Denali Therapeutics' net margin of 0.00%. Dr. Reddy's Laboratories' return on equity of 12.34% beat Denali Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Denali TherapeuticsN/A -52.20% -43.86%
Dr. Reddy's Laboratories 12.90%12.34%8.24%

Summary

Denali Therapeutics beats Dr. Reddy's Laboratories on 9 of the 17 factors compared between the two stocks.

How does Denali Therapeutics compare to Elanco Animal Health?

Elanco Animal Health (NYSE:ELAN) and Denali Therapeutics (NASDAQ:DNLI) are both medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their earnings, media sentiment, valuation, risk, institutional ownership, profitability, analyst recommendations and dividends.

Elanco Animal Health has a beta of 1.69, suggesting that its share price is 69% more volatile than the broader market. Comparatively, Denali Therapeutics has a beta of 1.03, suggesting that its share price is 3% more volatile than the broader market.

In the previous week, Elanco Animal Health had 13 more articles in the media than Denali Therapeutics. MarketBeat recorded 15 mentions for Elanco Animal Health and 2 mentions for Denali Therapeutics. Denali Therapeutics' average media sentiment score of 1.26 beat Elanco Animal Health's score of 1.18 indicating that Denali Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Elanco Animal Health
9 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Denali Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Elanco Animal Health presently has a consensus price target of $28.20, indicating a potential upside of 16.82%. Denali Therapeutics has a consensus price target of $34.25, indicating a potential upside of 77.19%. Given Denali Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Denali Therapeutics is more favorable than Elanco Animal Health.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Elanco Animal Health
1 Sell rating(s)
2 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.77
Denali Therapeutics
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.87

97.5% of Elanco Animal Health shares are owned by institutional investors. Comparatively, 92.9% of Denali Therapeutics shares are owned by institutional investors. 1.1% of Elanco Animal Health shares are owned by insiders. Comparatively, 12.5% of Denali Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Elanco Animal Health has higher revenue and earnings than Denali Therapeutics. Elanco Animal Health is trading at a lower price-to-earnings ratio than Denali Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Elanco Animal Health$4.72B2.56-$232M-$0.50N/A
Denali Therapeutics$330.53M9.28-$512.54M-$2.88N/A

Denali Therapeutics has a net margin of 0.00% compared to Elanco Animal Health's net margin of -4.95%. Elanco Animal Health's return on equity of 7.42% beat Denali Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Elanco Animal Health-4.95% 7.42% 3.66%
Denali Therapeutics N/A -52.20%-43.86%

Summary

Elanco Animal Health and Denali Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Denali Therapeutics compare to Arrowhead Pharmaceuticals?

Denali Therapeutics (NASDAQ:DNLI) and Arrowhead Pharmaceuticals (NASDAQ:ARWR) are both medical companies, but which is the better business? We will contrast the two companies based on the strength of their institutional ownership, analyst recommendations, media sentiment, profitability, valuation, earnings, risk and dividends.

In the previous week, Arrowhead Pharmaceuticals had 6 more articles in the media than Denali Therapeutics. MarketBeat recorded 8 mentions for Arrowhead Pharmaceuticals and 2 mentions for Denali Therapeutics. Denali Therapeutics' average media sentiment score of 1.26 beat Arrowhead Pharmaceuticals' score of 1.05 indicating that Denali Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Denali Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Arrowhead Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Denali Therapeutics currently has a consensus price target of $34.25, suggesting a potential upside of 77.19%. Arrowhead Pharmaceuticals has a consensus price target of $87.80, suggesting a potential upside of 20.37%. Given Denali Therapeutics' stronger consensus rating and higher possible upside, equities analysts clearly believe Denali Therapeutics is more favorable than Arrowhead Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Denali Therapeutics
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.87
Arrowhead Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.75

Arrowhead Pharmaceuticals has higher revenue and earnings than Denali Therapeutics. Arrowhead Pharmaceuticals is trading at a lower price-to-earnings ratio than Denali Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Denali Therapeutics$330.53M9.28-$512.54M-$2.88N/A
Arrowhead Pharmaceuticals$622.01M16.52-$1.63M-$2.15N/A

92.9% of Denali Therapeutics shares are held by institutional investors. Comparatively, 62.6% of Arrowhead Pharmaceuticals shares are held by institutional investors. 12.5% of Denali Therapeutics shares are held by insiders. Comparatively, 3.6% of Arrowhead Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Denali Therapeutics has a beta of 1.03, meaning that its share price is 3% more volatile than the broader market. Comparatively, Arrowhead Pharmaceuticals has a beta of 1.28, meaning that its share price is 28% more volatile than the broader market.

Denali Therapeutics has a net margin of 0.00% compared to Arrowhead Pharmaceuticals' net margin of -48.38%. Denali Therapeutics' return on equity of -52.20% beat Arrowhead Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Denali TherapeuticsN/A -52.20% -43.86%
Arrowhead Pharmaceuticals -48.38%-55.09%-18.13%

Summary

Denali Therapeutics beats Arrowhead Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does Denali Therapeutics compare to Abivax?

Denali Therapeutics (NASDAQ:DNLI) and Abivax (NASDAQ:ABVX) are both mid-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their analyst recommendations, institutional ownership, profitability, earnings, dividends, risk, valuation and media sentiment.

Denali Therapeutics' return on equity of -52.20% beat Abivax's return on equity.

Company Net Margins Return on Equity Return on Assets
Denali TherapeuticsN/A -52.20% -43.86%
Abivax N/A -99.02%-70.26%

Denali Therapeutics has a beta of 1.03, meaning that its stock price is 3% more volatile than the broader market. Comparatively, Abivax has a beta of 0.69, meaning that its stock price is 31% less volatile than the broader market.

Denali Therapeutics currently has a consensus target price of $34.25, suggesting a potential upside of 77.19%. Abivax has a consensus target price of $133.15, suggesting a potential upside of 60.43%. Given Denali Therapeutics' stronger consensus rating and higher probable upside, equities research analysts plainly believe Denali Therapeutics is more favorable than Abivax.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Denali Therapeutics
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.87
Abivax
1 Sell rating(s)
2 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.80

92.9% of Denali Therapeutics shares are owned by institutional investors. Comparatively, 47.9% of Abivax shares are owned by institutional investors. 12.5% of Denali Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Abivax has lower revenue, but higher earnings than Denali Therapeutics. Abivax is trading at a lower price-to-earnings ratio than Denali Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Denali Therapeutics$330.53M9.28-$512.54M-$2.88N/A
AbivaxN/AN/A-$380.27M-$5.21N/A

In the previous week, Abivax had 22 more articles in the media than Denali Therapeutics. MarketBeat recorded 24 mentions for Abivax and 2 mentions for Denali Therapeutics. Denali Therapeutics' average media sentiment score of 1.26 beat Abivax's score of 0.18 indicating that Denali Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Denali Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Abivax
3 Very Positive mention(s)
5 Positive mention(s)
4 Neutral mention(s)
3 Negative mention(s)
4 Very Negative mention(s)
Neutral

Summary

Denali Therapeutics beats Abivax on 12 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding DNLI and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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DNLI vs. The Competition

MetricDenali TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$3.07B$3.26B$6.26B$12.44B
Dividend YieldN/A2.33%2.69%5.30%
P/E Ratio-6.7117.7522.3524.23
Price / Sales9.28323.71555.60126.08
Price / CashN/A116.2742.3157.88
Price / Book2.806.559.826.73
Net Income-$512.54M$24.20M$3.56B$336.97M
7 Day Performance-4.35%-3.25%-1.16%0.79%
1 Month Performance5.63%0.48%3.85%5.38%
1 Year Performance38.77%47.06%27.33%34.55%

Denali Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
DNLI
Denali Therapeutics
3.7437 of 5 stars
$19.34
-0.1%
$34.25
+77.1%
+38.6%$3.07B$330.53MN/A430
BEAM
Beam Therapeutics
2.3268 of 5 stars
$28.64
flat
$46.83
+63.5%
+78.9%$2.95B$139.74MN/A510
RDY
Dr. Reddy's Laboratories
2.8702 of 5 stars
$13.60
0.0%
$16.90
+24.3%
-11.6%$11.35B$3.58B23.4427,811
ELAN
Elanco Animal Health
4.0025 of 5 stars
$21.77
+0.2%
$28.20
+29.5%
+76.0%$10.85B$4.72BN/A9,400
ARWR
Arrowhead Pharmaceuticals
3.1452 of 5 stars
$74.95
flat
$87.80
+17.1%
+331.8%$10.56B$829.45MN/A400

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This page (NASDAQ:DNLI) was last updated on 6/3/2026 by MarketBeat.com Staff.
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