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Denali Therapeutics (DNLI) Institutional Ownership

Denali Therapeutics logo
$17.61 -0.73 (-3.98%)
Closing price 10/16/2026 04:00 PM Eastern
Extended Trading
$17.92 +0.32 (+1.79%)
As of 10/16/2026 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Institutional Ownership Changes (13F Filings) for Denali Therapeutics (NASDAQ:DNLI)

Current
Institutional Ownership
Percentage
92.92%
Number of
Institutional Buyers
(last 12 months)
147
Total
Institutional Inflows
(last 12 months)
$1.07B
Number of
Institutional Sellers
(last 12 months)
67
Total
Institutional Outflows
(last 12 months)
$278.40M
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DNLI Institutional Buying and Selling by Quarter

Denali Therapeutics Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
10/14/2026B. Riley Wealth Advisors Inc.17,713$366K0.0%+38.2%0.011%
10/13/2026Contravisory Investment Management Inc.16,741$346K0.0%+14.1%0.010%
10/9/2026GAMMA Investing LLC2,236$46K0.0%+44.4%0.001%
9/9/2026WINTON GROUP Ltd14,100$363K0.0%-80.2%0.009%
9/9/2026Engineers Gate Manager LP57,430$1.48M0.0%+256.5%0.036%
9/9/2026Integrated Wealth Concepts LLC102,241$2.63M0.0%+2.7%0.064%
9/8/2026Allworth Financial LP1,834$47K0.0%+555.0%0.001%
9/8/2026Arizona State Retirement System37,196$957K0.0%-2.5%0.023%
9/8/2026Nykredit A S1,488$38K0.0%N/A0.001%
8/27/2026Corient Private Wealth LP11,704$301K0.0%N/A0.007%
8/26/2026HighTower Advisors LLC11,020$283K0.0%-7.9%0.007%
8/25/2026VIRGINIA RETIREMENT SYSTEMS ET Al14,300$368K0.0%N/A0.009%
8/21/2026Nykredit A S1,488$38K0.0%N/A0.001%
8/20/2026Alyeska Investment Group L.P.219,334$5.64M0.0%-88.7%0.137%
8/19/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC3,161,972$81.33M0.0%-28.7%1.978%
8/19/2026Wellington Management Group LLP52,618$1.35M0.0%-1.4%0.033%
8/18/2026Empowered Funds LLC14,428$371K0.0%N/A0.009%
8/18/2026Jefferies Financial Group Inc.34,425$885K0.0%N/A0.022%
8/17/2026Capstone Investment Advisors LLC20,964$539K0.0%N/A0.013%
8/17/2026Bank of America Corp DE1,230,957$31.66M0.0%N/A0.770%
8/15/2026Odyssean LLC125,062$3.22M0.5%N/A0.078%
8/15/2026Man Group plc139,065$3.58M0.0%N/A0.087%
8/15/2026Jupiter Topco LLC60,028$1.54M0.0%N/A0.038%
8/14/2026ADAR1 Capital Management LLC1,029,080$26.47M1.2%N/A0.644%
8/14/2026Legal & General Group Plc111,953$2.88M0.0%N/A0.070%
8/14/2026The Manufacturers Life Insurance Company117,348$3.02M0.0%N/A0.073%
8/13/2026Connor Clark & Lunn Investment Management Ltd.18,556$477K0.0%N/A0.012%
8/12/2026Elevation Point Wealth Partners LLC8,343$215K0.0%N/A0.005%
8/12/2026Ieq Capital LLC20,185$519K0.0%N/A0.013%
8/11/2026Allworth Financial LP1,834$47K0.0%N/A0.001%
8/11/2026B. Metzler seel. Sohn & Co. AG112,300$2.89M0.0%N/A0.071%
8/11/2026E Fund Management Co. Ltd.13,585$349K0.0%N/A0.009%
8/11/2026Edmond DE Rothschild Holding S.A.165,080$4.25M0.1%N/A0.104%
8/10/2026Great Lakes Advisors LLC145,045$3.73M0.0%N/A0.091%
8/7/2026BlackRock Inc.14,026,413$360.76M0.0%N/A8.838%
8/7/2026Deutsche Bank AG149,804$3.85M0.0%N/A0.094%
8/7/2026Mitsubishi UFJ Asset Management Co. Ltd.1,001$26K0.0%N/A0.001%
8/6/2026Global Retirement Partners LLC1,103$28K0.0%N/A0.001%
8/6/2026SCS Capital Management LLC197,998$5.09M0.0%N/A0.125%
8/6/2026Bank of New York Mellon Corp800,283$20.58M0.0%N/A0.504%
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8/6/2026State of Wyoming17,778$457K0.0%N/A0.011%
7/10/2026E. Ohman J or Asset Management AB160,000$4.12M0.1%N/A0.101%
7/10/2026Handelsbanken Fonder AB59,600$1.53M0.0%+36.1%0.038%
6/12/2026Defilade Capital Management L.P.1,359,969$26.11M3.7%+107.1%0.857%
6/4/2026Seven Fleet Capital Management LP35,286$677K0.2%N/A0.022%
5/22/2026Groupama Asset Managment207,130$3.98M0.1%+36.6%0.131%
5/22/2026Segall Bryant & Hamill LLC510,543$9.80M0.1%-4.9%0.322%
5/19/2026Bank of America Corp DE1,134,183$21.78M0.0%+21.7%0.715%
5/19/2026Stempoint Capital LP426,561$8.19M1.6%+1.8%0.269%
5/18/2026ADAR1 Capital Management LLC1,871,455$35.93M2.1%+3,490.9%1.179%
5/18/2026Amundi18,604$357K0.0%N/A0.012%
5/18/2026California State Teachers Retirement System162,576$3.12M0.0%+25.6%0.102%
5/18/2026Royal Bank of Canada7,535$145K0.0%-33.5%0.005%
5/18/2026Empowered Funds LLC15,787$303K0.0%+39.4%0.010%
5/16/2026The Manufacturers Life Insurance Company125,442$2.41M0.0%-31.9%0.079%
5/16/2026Quantinno Capital Management LP30,170$579K0.0%+14.7%0.019%
5/16/2026Masters Capital Management LLC600,000$11.52M0.4%-40.0%0.378%
5/14/2026Sei Investments Co.52,235$1.00M0.0%N/A0.033%
5/13/2026Cetera Investment Advisers11,059$212K0.0%N/A0.007%
5/8/2026PNC Financial Services Group Inc.9,220$177K0.0%+8.7%0.006%
5/7/2026Dimensional Fund Advisors LP2,692,175$51.69M0.0%+13.4%1.697%
5/7/2026KBC Group NV4,943$95K0.0%-21.1%0.003%
5/5/2026D.A. Davidson & CO.110,235$2.12M0.0%+3.1%0.069%
5/5/2026Bank of New York Mellon Corp768,039$14.75M0.0%+0.8%0.484%
5/4/2026Principal Financial Group Inc.1,478,486$28.39M0.0%-3.0%0.932%
5/4/2026Teachers Retirement System of The State of Kentucky166,181$3.19M0.0%+8.1%0.105%
5/1/2026Fifth Third Bancorp2,847$55K0.0%N/A0.002%
5/1/2026Candriam S.C.A.1,099,845$21.12M0.1%-5.7%0.693%
4/27/2026Y Intercept Hong Kong Ltd78,007$1.50M0.0%-16.6%0.049%
4/22/2026Pictet Asset Management Holding SA2,558,865$48.44M0.1%+92.5%1.614%
4/22/2026Sterling Capital Management LLC4,493$86K0.0%-37.9%0.003%
4/21/2026Contravisory Investment Management Inc.14,451$277K0.1%N/A0.009%
4/20/2026Breakwater Capital Group15,586$299K0.0%-4.8%0.010%
4/16/2026SG Americas Securities LLC46,642$896K0.0%-68.8%0.029%
2/27/2026Groupama Asset Managment151,591$2.50M0.0%+11.7%0.103%
2/19/2026T. Rowe Price Investment Management Inc.7,254,132$119.77M0.1%+28.7%4.946%
2/19/2026Invesco Ltd.291,936$4.82M0.0%+17.0%0.199%
2/18/2026Voloridge Investment Management LLC591,461$9.77M0.0%-36.8%0.403%
2/18/2026Vestal Point Capital LP465,000$7.68M0.3%N/A0.317%
2/18/2026Virtus Investment Advisers LLC14,795$244K0.1%+94.1%0.010%
2/18/2026Wellington Management Group LLP54,543$901K0.0%-7.9%0.037%
2/18/2026Susquehanna Portfolio Strategies LLC167,713$2.77M0.0%N/A0.114%
2/18/2026Tudor Investment Corp ET AL53,683$886K0.0%-4.8%0.037%
2/18/2026Millennium Management LLC369,767$6.11M0.0%-71.7%0.252%
2/18/2026Man Group plc48,994$809K0.0%N/A0.033%
2/18/2026Ishara Investments LP70,000$1.16M1.3%N/A0.048%
2/18/2026Casdin Capital LLC1,840,000$30.38M1.9%+106.7%1.255%
2/18/2026Clough Capital Partners L P51,830$856K0.1%N/A0.035%
2/17/2026Guggenheim Capital LLC12,468$206K0.0%-74.8%0.009%
2/17/2026ADAR1 Capital Management LLC52,116$860K0.1%+1.2%0.036%
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2/17/2026Burkehill Global Management LP200,000$3.30M0.2%N/A0.136%
2/17/2026AQR Capital Management LLC38,438$635K0.0%+59.2%0.026%
2/17/2026Trexquant Investment LP209,609$3.46M0.0%-51.3%0.143%
2/17/2026Jump Financial LLC40,608$670K0.0%-75.6%0.028%
2/17/2026Price T Rowe Associates Inc. MD3,915,951$64.65M0.0%-14.3%2.670%
2/17/2026T. Rowe Price Investment Management Inc.1,245,994$20.57M0.0%-77.9%0.850%
2/17/2026Ghisallo Capital Management LLC100,000$1.65M0.1%N/A0.068%
2/17/2026State of Wisconsin Investment Board73,581$1.22M0.0%-8.2%0.050%
2/17/2026ExodusPoint Capital Management LP1,023,253$16.89M0.1%N/A0.698%
2/17/2026Royal Bank of Canada11,335$187K0.0%-97.0%0.008%


DNLI Institutional Ownership - Frequently Asked Questions

During the previous two years, 257 institutional investors and hedge funds held shares of Denali Therapeutics. The most heavily invested institutionals were BlackRock Inc. ($360.76M), Vanguard Group Inc. ($215.59M), Baillie Gifford & Co. ($203.25M), FMR LLC ($163.44M), T. Rowe Price Investment Management Inc. ($119.77M), Temasek Holdings Private Ltd ($115.78M), and State Street Corp ($103.41M).Learn more on Denali Therapeutics' institutional investors.

92.92% of Denali Therapeutics' stock is owned by institutional investors. Learn more on DNLI's institutional investor holdings.

Of the 229 institutional investors that purchased Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: BlackRock Inc. ($14.03M), Norges Bank ($10.13M), FMR LLC ($7.78M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($4.64M), Holocene Advisors LP ($3.17M), ADAR1 Capital Management LLC ($2.86M), and Wellington Management Group LLP ($2.47M).

Institutional investors have bought a total of 54,805,998 shares in the last 24 months. This purchase volume represents approximately $1.07B in transactions.

Of the 67 institutional investors that sold Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: T. Rowe Price Investment Management Inc. ($4.39M), UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC ($2.55M), Alyeska Investment Group L.P. ($1.72M), Capital Research Global Investors ($1.03M), Millennium Management LLC ($937.40K), Price T Rowe Associates Inc. MD ($652.42K), and Marshall Wace LLP ($641.36K).

Institutional investors have sold a total of 15,331,833 shares in the last 24 months. This volume of shares sold represents approximately $278.40M in transactions.


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Institutional ownership data for NASDAQ:DNLI is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 10/14/2026. New 13F filings are added each quarter as they're published.
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