Denali Therapeutics (DNLI) Institutional Ownership

$19.89 -0.32 (-1.60%)

As of 09:42 AM Eastern

Current Institutional Ownership Percentage: 92.92%
Number of Institutional Buyers (last 12 months): 146
Total Institutional Inflows (last 12 months): $677.54M

Number of Institutional Sellers (last 12 months): 79
Total Institutional Outflows (last 12 months): $233.35M

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DNLI Institutional Buying and Selling by Quarter

Denali Therapeutics Major Shareholders & Ownership History

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Reporting Date	Major Shareholder Name	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
5/22/2026	Groupama Asset Managment	207,130	$3.98M	0.1%	+36.6%	0.131%
5/22/2026	Segall Bryant & Hamill LLC	510,543	$9.80M	0.1%	-4.9%	0.322%
5/19/2026	Bank of America Corp DE	1,134,183	$21.78M	0.0%	+21.7%	0.715%
5/19/2026	Stempoint Capital LP	426,561	$8.19M	1.6%	+1.8%	0.269%
5/18/2026	ADAR1 Capital Management LLC	1,871,455	$35.93M	2.1%	+3,490.9%	1.179%
5/18/2026	Amundi	18,604	$357K	0.0%	N/A	0.012%
5/18/2026	California State Teachers Retirement System	162,576	$3.12M	0.0%	+25.6%	0.102%
5/18/2026	Royal Bank of Canada	7,535	$145K	0.0%	-33.5%	0.005%
5/18/2026	Empowered Funds LLC	15,787	$303K	0.0%	+39.4%	0.010%
5/16/2026	The Manufacturers Life Insurance Company	125,442	$2.41M	0.0%	-31.9%	0.079%
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5/16/2026	Quantinno Capital Management LP	30,170	$579K	0.0%	+14.7%	0.019%
5/16/2026	Masters Capital Management LLC	600,000	$11.52M	0.4%	-40.0%	0.378%
5/14/2026	Sei Investments Co.	52,235	$1.00M	0.0%	N/A	0.033%
5/13/2026	Cetera Investment Advisers	11,059	$212K	0.0%	N/A	0.007%
5/8/2026	PNC Financial Services Group Inc.	9,220	$177K	0.0%	+8.7%	0.006%
5/7/2026	Dimensional Fund Advisors LP	2,692,175	$51.69M	0.0%	+13.4%	1.697%
5/7/2026	KBC Group NV	4,943	$95K	0.0%	-21.1%	0.003%
5/5/2026	D.A. Davidson & CO.	110,235	$2.12M	0.0%	+3.1%	0.069%
5/5/2026	Bank of New York Mellon Corp	768,039	$14.75M	0.0%	+0.8%	0.484%
5/4/2026	Principal Financial Group Inc.	1,478,486	$28.39M	0.0%	-3.0%	0.932%
5/4/2026	Teachers Retirement System of The State of Kentucky	166,181	$3.19M	0.0%	+8.1%	0.105%
5/1/2026	Fifth Third Bancorp	2,847	$55K	0.0%	N/A	0.002%
5/1/2026	Candriam S.C.A.	1,099,845	$21.12M	0.1%	-5.7%	0.693%
4/27/2026	Y Intercept Hong Kong Ltd	78,007	$1.50M	0.0%	-16.6%	0.049%
4/22/2026	Pictet Asset Management Holding SA	2,558,865	$48.44M	0.1%	+92.5%	1.614%
4/22/2026	Sterling Capital Management LLC	4,493	$86K	0.0%	-37.9%	0.003%
4/21/2026	Contravisory Investment Management Inc.	14,451	$277K	0.1%	N/A	0.009%
4/20/2026	Breakwater Capital Group	15,586	$299K	0.0%	-4.8%	0.010%
4/16/2026	SG Americas Securities LLC	46,642	$896K	0.0%	-68.8%	0.029%
2/27/2026	Groupama Asset Managment	151,591	$2.50M	0.0%	+11.7%	0.103%
2/19/2026	T. Rowe Price Investment Management Inc.	7,254,132	$119.77M	0.1%	+28.7%	4.946%
2/19/2026	Invesco Ltd.	291,936	$4.82M	0.0%	+17.0%	0.199%
2/18/2026	Voloridge Investment Management LLC	591,461	$9.77M	0.0%	-36.8%	0.403%
2/18/2026	Vestal Point Capital LP	465,000	$7.68M	0.3%	N/A	0.317%
2/18/2026	Virtus Investment Advisers LLC	14,795	$244K	0.1%	+94.1%	0.010%
2/18/2026	Wellington Management Group LLP	54,543	$901K	0.0%	-7.9%	0.037%
2/18/2026	Susquehanna Portfolio Strategies LLC	167,713	$2.77M	0.0%	N/A	0.114%
2/18/2026	Tudor Investment Corp ET AL	53,683	$886K	0.0%	-4.8%	0.037%
2/18/2026	Millennium Management LLC	369,767	$6.11M	0.0%	-71.7%	0.252%
2/18/2026	Man Group plc	48,994	$809K	0.0%	N/A	0.033%
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2/18/2026	Ishara Investments LP	70,000	$1.16M	1.3%	N/A	0.048%
2/18/2026	Casdin Capital LLC	1,840,000	$30.38M	1.9%	+106.7%	1.255%
2/18/2026	Clough Capital Partners L P	51,830	$856K	0.1%	N/A	0.035%
2/17/2026	Guggenheim Capital LLC	12,468	$206K	0.0%	-74.8%	0.009%
2/17/2026	ADAR1 Capital Management LLC	52,116	$860K	0.1%	+1.2%	0.036%
2/17/2026	Burkehill Global Management LP	200,000	$3.30M	0.2%	N/A	0.136%
2/17/2026	AQR Capital Management LLC	38,438	$635K	0.0%	+59.2%	0.026%
2/17/2026	Trexquant Investment LP	209,609	$3.46M	0.0%	-51.3%	0.143%
2/17/2026	Jump Financial LLC	40,608	$670K	0.0%	-75.6%	0.028%
2/17/2026	Price T Rowe Associates Inc. MD	3,915,951	$64.65M	0.0%	-14.3%	2.670%
2/17/2026	T. Rowe Price Investment Management Inc.	1,245,994	$20.57M	0.0%	-77.9%	0.850%
2/17/2026	Ghisallo Capital Management LLC	100,000	$1.65M	0.1%	N/A	0.068%
2/17/2026	State of Wisconsin Investment Board	73,581	$1.22M	0.0%	-8.2%	0.050%
2/17/2026	ExodusPoint Capital Management LP	1,023,253	$16.89M	0.1%	N/A	0.698%
2/17/2026	Royal Bank of Canada	11,335	$187K	0.0%	-97.0%	0.008%
2/17/2026	Graham Capital Management L.P.	18,121	$299K	0.0%	-53.9%	0.012%
2/17/2026	Persistent Asset Partners Ltd	5,670	$94K	0.0%	N/A	0.004%
2/17/2026	Aster Capital Management DIFC Ltd	3,451	$57K	0.0%	N/A	0.002%
2/17/2026	Temasek Holdings Private Ltd	7,012,974	$115.78M	0.4%	+30.9%	4.782%
2/16/2026	Barclays PLC	407,359	$6.73M	0.0%	-6.8%	0.278%
2/13/2026	Marshall Wace LLP	763,892	$12.61M	0.0%	-2.9%	0.521%
2/13/2026	The Manufacturers Life Insurance Company	184,238	$3.03M	0.0%	-10.5%	0.126%
2/13/2026	Segall Bryant & Hamill LLC	537,000	$8.87M	0.1%	+4.7%	0.366%
2/13/2026	Hudson Bay Capital Management LP	450,000	$7.43M	0.0%	+47.5%	0.307%
2/13/2026	Quarry LP	7,000	$116K	0.0%	+60.0%	0.005%
2/13/2026	Schroder Investment Management Group	450,985	$7.40M	0.0%	+115.2%	0.308%
2/13/2026	Rafferty Asset Management LLC	191,567	$3.16M	0.0%	+4.7%	0.131%
2/13/2026	Headlands Technologies LLC	46,383	$766K	0.1%	N/A	0.032%
2/13/2026	Integrated Wealth Concepts LLC	94,582	$1.56M	0.0%	+3.9%	0.064%
2/13/2026	Alyeska Investment Group L.P.	859,108	$14.18M	0.0%	N/A	0.586%
2/13/2026	Siren L.L.C.	1,396,513	$23.06M	0.7%	+70.0%	0.952%
2/13/2026	Charles Schwab Investment Management Inc.	1,200,475	$19.82M	0.0%	+4.3%	0.819%
2/13/2026	State Street Corp	6,263,371	$103.41M	0.0%	+14.6%	4.271%
2/13/2026	Martingale Asset Management L P	18,535	$306K	0.0%	N/A	0.013%
2/13/2026	UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	4,983,726	$82.28M	0.0%	-8.8%	3.398%
2/13/2026	Wells Fargo & Company MN	193,681	$3.20M	0.0%	+85.9%	0.132%
2/12/2026	HRT Financial LP	78,352	$1.29M	0.0%	N/A	0.053%
2/12/2026	MetLife Investment Management LLC	75,164	$1.24M	0.0%	-4.9%	0.051%
2/12/2026	Renaissance Technologies LLC	10,700	$177K	0.0%	-82.1%	0.007%
2/12/2026	Dimensional Fund Advisors LP	2,374,303	$39.20M	0.0%	+0.7%	1.619%
2/12/2026	Ensign Peak Advisors Inc	515,721	$8.52M	0.0%	-3.4%	0.352%
2/12/2026	Marex Group plc	287,001	$4.74M	0.0%	-1.4%	0.196%
2/12/2026	Ironwood Investment Management LLC	50,933	$841K	0.4%	-3.5%	0.035%
2/12/2026	Alps Advisors Inc.	120,718	$1.99M	0.0%	+71.9%	0.082%
2/12/2026	Swiss National Bank	273,800	$4.52M	0.0%	+2.4%	0.187%
2/12/2026	Polen Capital Management LLC	26,900	$444K	0.0%	N/A	0.018%
2/12/2026	Monashee Investment Management LLC	91,620	$1.51M	0.9%	N/A	0.062%
2/12/2026	Nuveen LLC	275,508	$4.55M	0.0%	-3.3%	0.188%
2/11/2026	Deutsche Bank AG	105,086	$1.74M	0.0%	-49.4%	0.072%
2/11/2026	Franklin Resources Inc.	60,270	$995K	0.0%	-6.8%	0.041%
The math on the SpaceX IPO is broken (Ad) SpaceX is expected to go public at a $1.75 trillion valuation. For investors to see a 10x return, the company would have to reach $17.5 trillion - more than Apple, Microsoft, and Nvidia combined. But there may be a smarter play: a tiny supplier, just 1/60th the size of SpaceX, has already shipped 5 billion critical components to the company over the last decade. Once SpaceX goes public this June, Wall Street analysts will likely tear through the supply chain and put this under-the-radar vendor on the map. Get the full details on this overlooked supplier before the June IPO. Discover the under-the-radar SpaceX supplier before Wall Street does
2/11/2026	Capital Research Global Investors	3,729,244	$61.57M	0.0%	-21.7%	2.543%
2/11/2026	WINTON GROUP Ltd	12,700	$210K	0.0%	N/A	0.009%
2/11/2026	State of Wyoming	2,686	$44K	0.0%	+24.7%	0.002%
2/10/2026	TD Asset Management Inc	339,410	$5.60M	0.0%	-14.0%	0.231%
2/10/2026	1492 Capital Management LLC	67,487	$1.11M	0.4%	N/A	0.046%
2/10/2026	Goldman Sachs Group Inc.	3,835,803	$63.33M	0.0%	+77.3%	2.615%
2/10/2026	Norges Bank	5,119,622	$84.53M	0.0%	N/A	3.491%
2/10/2026	Eurizon Capital SGR S.p.A.	5,045	$83K	0.0%	N/A	0.003%
2/10/2026	SBI Okasan Asset Management Co.Ltd.	18,000	$298K	0.0%	N/A	0.012%
2/10/2026	Intech Investment Management LLC	52,632	$869K	0.0%	+12.5%	0.036%

DNLI Institutional Ownership - Frequently Asked Questions

During the previous two years, 243 institutional investors and hedge funds held shares of Denali Therapeutics. The most heavily invested institutionals were Vanguard Group Inc. ($215.59M), Baillie Gifford & Co. ($203.25M), FMR LLC ($163.44M), T. Rowe Price Investment Management Inc. ($119.77M), Temasek Holdings Private Ltd ($115.78M), State Street Corp ($103.41M), and Norges Bank ($84.53M).Learn more on Denali Therapeutics' institutional investors.

92.92% of Denali Therapeutics' stock is owned by institutional investors. Learn more on DNLI's institutional investor holdings.

Of the 216 institutional investors that purchased Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Norges Bank ($10.13M), FMR LLC ($7.78M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($4.64M), Holocene Advisors LP ($3.17M), Wellington Management Group LLP ($2.47M), Goldman Sachs Group Inc. ($2.29M), and Vanguard Group Inc. ($2.09M).

Institutional investors have bought a total of 42,708,824 shares in the last 24 months. This purchase volume represents approximately $677.54M in transactions.

Of the 79 institutional investors that sold Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: T. Rowe Price Investment Management Inc. ($4.39M), Marshall Wace LLP ($1.42M), UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC ($1.28M), Capital Research Global Investors ($1.03M), Millennium Management LLC ($937.40K), Camber Capital Management LP ($850K), and Price T Rowe Associates Inc. MD ($652.42K).

Institutional investors have sold a total of 14,669,463 shares in the last 24 months. This volume of shares sold represents approximately $233.35M in transactions.

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This page (NASDAQ:DNLI) was last updated on 5/28/2026 by MarketBeat.com Staff.

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Denali Therapeutics (DNLI) Institutional Ownership

DNLI Institutional Buying and Selling by Quarter

Denali Therapeutics Major Shareholders & Ownership History

DNLI Institutional Ownership - Frequently Asked Questions

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Denali Therapeutics (DNLI) Institutional Ownership

Institutional Ownership Changes (13F Filings) for Denali Therapeutics (NASDAQ:DNLI)

DNLI Institutional Buying and Selling by Quarter

Denali Therapeutics Major Shareholders & Ownership History

DNLI Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of DNLI shares?

What percentage of Denali Therapeutics' stock is owned by institutional investors?

Which institutional investors have been buying Denali Therapeutics' stock?

How much institutional buying is happening at Denali Therapeutics?

Which of Denali Therapeutics' major shareholders have been selling company stock?

How much institutional selling is happening at Denali Therapeutics?

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