Denali Therapeutics (DNLI) Institutional Ownership

$20.39 -0.08 (-0.39%)

Closing price 09/25/2026 04:00 PM Eastern

Extended Trading

$20.40 +0.00 (+0.02%)

As of 09/25/2026 07:30 PM Eastern

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Current Institutional Ownership Percentage: 92.92%
Number of Institutional Buyers (last 12 months): 145
Total Institutional Inflows (last 12 months): $1.07B

Number of Institutional Sellers (last 12 months): 69
Total Institutional Outflows (last 12 months): $278.71M

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DNLI Institutional Buying and Selling by Quarter

Denali Therapeutics Major Shareholders & Ownership History

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Reporting Date	Major Shareholder Name	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
9/9/2026	WINTON GROUP Ltd	14,100	$363K	0.0%	-80.2%	0.009%
9/9/2026	Engineers Gate Manager LP	57,430	$1.48M	0.0%	+256.5%	0.036%
9/9/2026	Integrated Wealth Concepts LLC	102,241	$2.63M	0.0%	+2.7%	0.064%
9/8/2026	Allworth Financial LP	1,834	$47K	0.0%	+555.0%	0.001%
9/8/2026	Arizona State Retirement System	37,196	$957K	0.0%	-2.5%	0.023%
9/8/2026	Nykredit A S	1,488	$38K	0.0%	N/A	0.001%
8/27/2026	Corient Private Wealth LP	11,704	$301K	0.0%	N/A	0.007%
8/26/2026	HighTower Advisors LLC	11,020	$283K	0.0%	-7.9%	0.007%
8/25/2026	VIRGINIA RETIREMENT SYSTEMS ET Al	14,300	$368K	0.0%	N/A	0.009%
8/21/2026	Nykredit A S	1,488	$38K	0.0%	N/A	0.001%
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8/20/2026	Alyeska Investment Group L.P.	219,334	$5.64M	0.0%	-88.7%	0.137%
8/19/2026	UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	3,161,972	$81.33M	0.0%	-28.7%	1.978%
8/19/2026	Wellington Management Group LLP	52,618	$1.35M	0.0%	-1.4%	0.033%
8/18/2026	Empowered Funds LLC	14,428	$371K	0.0%	N/A	0.009%
8/18/2026	Jefferies Financial Group Inc.	34,425	$885K	0.0%	N/A	0.022%
8/17/2026	Capstone Investment Advisors LLC	20,964	$539K	0.0%	N/A	0.013%
8/17/2026	Bank of America Corp DE	1,230,957	$31.66M	0.0%	N/A	0.770%
8/15/2026	Odyssean LLC	125,062	$3.22M	0.5%	N/A	0.078%
8/15/2026	Man Group plc	139,065	$3.58M	0.0%	N/A	0.087%
8/15/2026	Jupiter Topco LLC	60,028	$1.54M	0.0%	N/A	0.038%
8/14/2026	ADAR1 Capital Management LLC	1,029,080	$26.47M	1.2%	N/A	0.644%
8/14/2026	Legal & General Group Plc	111,953	$2.88M	0.0%	N/A	0.070%
8/14/2026	The Manufacturers Life Insurance Company	117,348	$3.02M	0.0%	N/A	0.073%
8/13/2026	Connor Clark & Lunn Investment Management Ltd.	18,556	$477K	0.0%	N/A	0.012%
8/12/2026	Elevation Point Wealth Partners LLC	8,343	$215K	0.0%	N/A	0.005%
8/12/2026	Ieq Capital LLC	20,185	$519K	0.0%	N/A	0.013%
8/11/2026	Allworth Financial LP	1,834	$47K	0.0%	N/A	0.001%
8/11/2026	B. Metzler seel. Sohn & Co. AG	112,300	$2.89M	0.0%	N/A	0.071%
8/11/2026	E Fund Management Co. Ltd.	13,585	$349K	0.0%	N/A	0.009%
8/11/2026	Edmond DE Rothschild Holding S.A.	165,080	$4.25M	0.1%	N/A	0.104%
8/10/2026	Great Lakes Advisors LLC	145,045	$3.73M	0.0%	N/A	0.091%
8/7/2026	BlackRock Inc.	14,026,413	$360.76M	0.0%	N/A	8.838%
8/7/2026	Deutsche Bank AG	149,804	$3.85M	0.0%	N/A	0.094%
8/7/2026	Mitsubishi UFJ Asset Management Co. Ltd.	1,001	$26K	0.0%	N/A	0.001%
8/6/2026	Global Retirement Partners LLC	1,103	$28K	0.0%	N/A	0.001%
8/6/2026	SCS Capital Management LLC	197,998	$5.09M	0.0%	N/A	0.125%
8/6/2026	Bank of New York Mellon Corp	800,283	$20.58M	0.0%	N/A	0.504%
8/6/2026	State of Wyoming	17,778	$457K	0.0%	N/A	0.011%
7/10/2026	E. Ohman J or Asset Management AB	160,000	$4.12M	0.1%	N/A	0.101%
7/10/2026	Handelsbanken Fonder AB	59,600	$1.53M	0.0%	+36.1%	0.038%
Buffett's Final Warning: "The Dollar Is Going to Hell" (Ad) On May 3rd, 2025, Warren Buffett looked at his shareholders for the last time and said: "The dollar is going to hell." Ray Dalio agrees. The founder of Bridgewater Associates ($150 billion AUM) calls it a "debt death spiral." But there's a specific asset class and investment system that actually thrives when the dollar collapses. Watch how to protect yourself from what Dalio and Buffett see coming (free training).
6/12/2026	Defilade Capital Management L.P.	1,359,969	$26.11M	3.7%	+107.1%	0.857%
6/4/2026	Seven Fleet Capital Management LP	35,286	$677K	0.2%	N/A	0.022%
5/22/2026	Groupama Asset Managment	207,130	$3.98M	0.1%	+36.6%	0.131%
5/22/2026	Segall Bryant & Hamill LLC	510,543	$9.80M	0.1%	-4.9%	0.322%
5/19/2026	Bank of America Corp DE	1,134,183	$21.78M	0.0%	+21.7%	0.715%
5/19/2026	Stempoint Capital LP	426,561	$8.19M	1.6%	+1.8%	0.269%
5/18/2026	ADAR1 Capital Management LLC	1,871,455	$35.93M	2.1%	+3,490.9%	1.179%
5/18/2026	Amundi	18,604	$357K	0.0%	N/A	0.012%
5/18/2026	California State Teachers Retirement System	162,576	$3.12M	0.0%	+25.6%	0.102%
5/18/2026	Royal Bank of Canada	7,535	$145K	0.0%	-33.5%	0.005%
5/18/2026	Empowered Funds LLC	15,787	$303K	0.0%	+39.4%	0.010%
5/16/2026	The Manufacturers Life Insurance Company	125,442	$2.41M	0.0%	-31.9%	0.079%
5/16/2026	Quantinno Capital Management LP	30,170	$579K	0.0%	+14.7%	0.019%
5/16/2026	Masters Capital Management LLC	600,000	$11.52M	0.4%	-40.0%	0.378%
5/14/2026	Sei Investments Co.	52,235	$1.00M	0.0%	N/A	0.033%
5/13/2026	Cetera Investment Advisers	11,059	$212K	0.0%	N/A	0.007%
5/8/2026	PNC Financial Services Group Inc.	9,220	$177K	0.0%	+8.7%	0.006%
5/7/2026	Dimensional Fund Advisors LP	2,692,175	$51.69M	0.0%	+13.4%	1.697%
5/7/2026	KBC Group NV	4,943	$95K	0.0%	-21.1%	0.003%
5/5/2026	D.A. Davidson & CO.	110,235	$2.12M	0.0%	+3.1%	0.069%
5/5/2026	Bank of New York Mellon Corp	768,039	$14.75M	0.0%	+0.8%	0.484%
5/4/2026	Principal Financial Group Inc.	1,478,486	$28.39M	0.0%	-3.0%	0.932%
5/4/2026	Teachers Retirement System of The State of Kentucky	166,181	$3.19M	0.0%	+8.1%	0.105%
5/1/2026	Fifth Third Bancorp	2,847	$55K	0.0%	N/A	0.002%
5/1/2026	Candriam S.C.A.	1,099,845	$21.12M	0.1%	-5.7%	0.693%
4/27/2026	Y Intercept Hong Kong Ltd	78,007	$1.50M	0.0%	-16.6%	0.049%
4/22/2026	Pictet Asset Management Holding SA	2,558,865	$48.44M	0.1%	+92.5%	1.614%
4/22/2026	Sterling Capital Management LLC	4,493	$86K	0.0%	-37.9%	0.003%
4/21/2026	Contravisory Investment Management Inc.	14,451	$277K	0.1%	N/A	0.009%
4/20/2026	Breakwater Capital Group	15,586	$299K	0.0%	-4.8%	0.010%
4/16/2026	SG Americas Securities LLC	46,642	$896K	0.0%	-68.8%	0.029%
2/27/2026	Groupama Asset Managment	151,591	$2.50M	0.0%	+11.7%	0.103%
2/19/2026	T. Rowe Price Investment Management Inc.	7,254,132	$119.77M	0.1%	+28.7%	4.946%
2/19/2026	Invesco Ltd.	291,936	$4.82M	0.0%	+17.0%	0.199%
2/18/2026	Voloridge Investment Management LLC	591,461	$9.77M	0.0%	-36.8%	0.403%
2/18/2026	Vestal Point Capital LP	465,000	$7.68M	0.3%	N/A	0.317%
2/18/2026	Virtus Investment Advisers LLC	14,795	$244K	0.1%	+94.1%	0.010%
2/18/2026	Wellington Management Group LLP	54,543	$901K	0.0%	-7.9%	0.037%
2/18/2026	Susquehanna Portfolio Strategies LLC	167,713	$2.77M	0.0%	N/A	0.114%
2/18/2026	Tudor Investment Corp ET AL	53,683	$886K	0.0%	-4.8%	0.037%
2/18/2026	Millennium Management LLC	369,767	$6.11M	0.0%	-71.7%	0.252%
2/18/2026	Man Group plc	48,994	$809K	0.0%	N/A	0.033%
2/18/2026	Ishara Investments LP	70,000	$1.16M	1.3%	N/A	0.048%
2/18/2026	Casdin Capital LLC	1,840,000	$30.38M	1.9%	+106.7%	1.255%
2/18/2026	Clough Capital Partners L P	51,830	$856K	0.1%	N/A	0.035%
2/17/2026	Guggenheim Capital LLC	12,468	$206K	0.0%	-74.8%	0.009%
2/17/2026	ADAR1 Capital Management LLC	52,116	$860K	0.1%	+1.2%	0.036%
2/17/2026	Burkehill Global Management LP	200,000	$3.30M	0.2%	N/A	0.136%
2/17/2026	AQR Capital Management LLC	38,438	$635K	0.0%	+59.2%	0.026%
2/17/2026	Trexquant Investment LP	209,609	$3.46M	0.0%	-51.3%	0.143%
Buffett's Final Warning: "The Dollar Is Going to Hell" (Ad) On May 3rd, 2025, Warren Buffett looked at his shareholders for the last time and said: "The dollar is going to hell." Ray Dalio agrees. The founder of Bridgewater Associates ($150 billion AUM) calls it a "debt death spiral." But there's a specific asset class and investment system that actually thrives when the dollar collapses. Watch how to protect yourself from what Dalio and Buffett see coming (free training).
2/17/2026	Jump Financial LLC	40,608	$670K	0.0%	-75.6%	0.028%
2/17/2026	Price T Rowe Associates Inc. MD	3,915,951	$64.65M	0.0%	-14.3%	2.670%
2/17/2026	T. Rowe Price Investment Management Inc.	1,245,994	$20.57M	0.0%	-77.9%	0.850%
2/17/2026	Ghisallo Capital Management LLC	100,000	$1.65M	0.1%	N/A	0.068%
2/17/2026	State of Wisconsin Investment Board	73,581	$1.22M	0.0%	-8.2%	0.050%
2/17/2026	ExodusPoint Capital Management LP	1,023,253	$16.89M	0.1%	N/A	0.698%
2/17/2026	Royal Bank of Canada	11,335	$187K	0.0%	-97.0%	0.008%
2/17/2026	Graham Capital Management L.P.	18,121	$299K	0.0%	-53.9%	0.012%
2/17/2026	Persistent Asset Partners Ltd	5,670	$94K	0.0%	N/A	0.004%
2/17/2026	Aster Capital Management DIFC Ltd	3,451	$57K	0.0%	N/A	0.002%

DNLI Institutional Ownership - Frequently Asked Questions

During the previous two years, 258 institutional investors and hedge funds held shares of Denali Therapeutics. The most heavily invested institutionals were BlackRock Inc. ($360.76M), Vanguard Group Inc. ($215.59M), Baillie Gifford & Co. ($203.25M), FMR LLC ($163.44M), T. Rowe Price Investment Management Inc. ($119.77M), Temasek Holdings Private Ltd ($115.78M), and State Street Corp ($103.41M).Learn more on Denali Therapeutics' institutional investors.

92.92% of Denali Therapeutics' stock is owned by institutional investors. Learn more on DNLI's institutional investor holdings.

Of the 230 institutional investors that purchased Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: BlackRock Inc. ($14.03M), Norges Bank ($10.13M), FMR LLC ($7.78M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($4.64M), Holocene Advisors LP ($3.17M), ADAR1 Capital Management LLC ($2.86M), and Wellington Management Group LLP ($2.47M).

Institutional investors have bought a total of 54,798,344 shares in the last 24 months. This purchase volume represents approximately $1.07B in transactions.

Of the 69 institutional investors that sold Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: T. Rowe Price Investment Management Inc. ($4.39M), UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC ($2.55M), Alyeska Investment Group L.P. ($1.72M), Capital Research Global Investors ($1.03M), Millennium Management LLC ($937.40K), Price T Rowe Associates Inc. MD ($652.42K), and Marshall Wace LLP ($641.36K).

Institutional investors have sold a total of 15,353,186 shares in the last 24 months. This volume of shares sold represents approximately $278.71M in transactions.

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Institutional ownership data for NASDAQ:DNLI is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 9/9/2026. New 13F filings are added each quarter as they're published.

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Denali Therapeutics (DNLI) Institutional Ownership

DNLI Institutional Buying and Selling by Quarter

Denali Therapeutics Major Shareholders & Ownership History

DNLI Institutional Ownership - Frequently Asked Questions

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Denali Therapeutics (DNLI) Institutional Ownership

Institutional Ownership Changes (13F Filings) for Denali Therapeutics (NASDAQ:DNLI)

DNLI Institutional Buying and Selling by Quarter

Denali Therapeutics Major Shareholders & Ownership History

DNLI Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of DNLI shares?

What percentage of Denali Therapeutics' stock is owned by institutional investors?

Which institutional investors have been buying Denali Therapeutics' stock?

How much institutional buying is happening at Denali Therapeutics?

Which of Denali Therapeutics' major shareholders have been selling company stock?

How much institutional selling is happening at Denali Therapeutics?

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