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Denali Therapeutics (DNLI) Institutional Ownership

Denali Therapeutics logo
$22.28 -0.52 (-2.28%)
As of 09/4/2026 04:00 PM Eastern
Compare

Institutional Ownership Changes (13F Filings) for Denali Therapeutics (NASDAQ:DNLI)

Current
Institutional Ownership
Percentage
92.92%
Number of
Institutional Buyers
(last 12 months)
144
Total
Institutional Inflows
(last 12 months)
$1.17B
Number of
Institutional Sellers
(last 12 months)
68
Total
Institutional Outflows
(last 12 months)
$277.22M
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DNLI Institutional Buying and Selling by Quarter

Denali Therapeutics Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
8/27/2026 Corient Private Wealth LP11,704$301K0.0%N/A0.007%
8/26/2026 HighTower Advisors LLC11,020$283K0.0%-7.9%0.007%
8/25/2026 VIRGINIA RETIREMENT SYSTEMS ET Al14,300$368K0.0%N/A0.009%
8/24/2026 California State Teachers Retirement System3,911,652$100.61M0.0%+2,306.0%2.447%
8/21/2026 Nykredit A S1,488$38K0.0%N/A0.001%
8/20/2026 Alyeska Investment Group L.P.219,334$5.64M0.0%-88.7%0.137%
8/19/2026 UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC3,161,972$81.33M0.0%-28.7%1.978%
8/19/2026 Wellington Management Group LLP52,618$1.35M0.0%-1.4%0.033%
8/18/2026 Empowered Funds LLC14,428$371K0.0%N/A0.009%
8/18/2026Jefferies Financial Group Inc.34,425$885K0.0%N/A0.022%
8/17/2026 Capstone Investment Advisors LLC20,964$539K0.0%N/A0.013%
8/17/2026 Bank of America Corp DE1,230,957$31.66M0.0%N/A0.770%
8/15/2026 Odyssean LLC125,062$3.22M0.5%N/A0.078%
8/15/2026 Man Group plc139,065$3.58M0.0%N/A0.087%
8/15/2026 Jupiter Topco LLC60,028$1.54M0.0%N/A0.038%
8/14/2026 ADAR1 Capital Management LLC1,029,080$26.47M1.2%N/A0.644%
8/14/2026 Legal & General Group Plc111,953$2.88M0.0%N/A0.070%
8/14/2026 The Manufacturers Life Insurance Company117,348$3.02M0.0%N/A0.073%
8/13/2026 Connor Clark & Lunn Investment Management Ltd.18,556$477K0.0%N/A0.012%
8/12/2026 Elevation Point Wealth Partners LLC8,343$215K0.0%N/A0.005%
8/12/2026 Ieq Capital LLC20,185$519K0.0%N/A0.013%
8/11/2026 Allworth Financial LP1,834$47K0.0%N/A0.001%
8/11/2026 B. Metzler seel. Sohn & Co. AG112,300$2.89M0.0%N/A0.071%
8/11/2026 E Fund Management Co. Ltd.13,585$349K0.0%N/A0.009%
8/11/2026 Edmond DE Rothschild Holding S.A.165,080$4.25M0.1%N/A0.104%
8/10/2026 Great Lakes Advisors LLC145,045$3.73M0.0%N/A0.091%
8/7/2026 BlackRock Inc.14,026,413$360.76M0.0%N/A8.838%
8/7/2026 Deutsche Bank AG149,804$3.85M0.0%N/A0.094%
8/7/2026 Mitsubishi UFJ Asset Management Co. Ltd.1,001$26K0.0%N/A0.001%
8/6/2026 Global Retirement Partners LLC1,103$28K0.0%N/A0.001%
8/6/2026 SCS Capital Management LLC197,998$5.09M0.0%N/A0.125%
8/6/2026 Bank of New York Mellon Corp800,283$20.58M0.0%N/A0.504%
8/6/2026 State of Wyoming17,778$457K0.0%N/A0.011%
7/10/2026 E. Ohman J or Asset Management AB160,000$4.12M0.1%N/A0.101%
7/10/2026 Handelsbanken Fonder AB59,600$1.53M0.0%+36.1%0.038%
6/12/2026 Defilade Capital Management L.P.1,359,969$26.11M3.7%+107.1%0.857%
6/4/2026 Seven Fleet Capital Management LP35,286$677K0.2%N/A0.022%
5/22/2026 Groupama Asset Managment207,130$3.98M0.1%+36.6%0.131%
5/22/2026 Segall Bryant & Hamill LLC510,543$9.80M0.1%-4.9%0.322%
5/19/2026 Bank of America Corp DE1,134,183$21.78M0.0%+21.7%0.715%
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5/19/2026 Stempoint Capital LP426,561$8.19M1.6%+1.8%0.269%
5/18/2026 ADAR1 Capital Management LLC1,871,455$35.93M2.1%+3,490.9%1.179%
5/18/2026 Amundi18,604$357K0.0%N/A0.012%
5/18/2026 California State Teachers Retirement System162,576$3.12M0.0%+25.6%0.102%
5/18/2026 Royal Bank of Canada7,535$145K0.0%-33.5%0.005%
5/18/2026 Empowered Funds LLC15,787$303K0.0%+39.4%0.010%
5/16/2026 The Manufacturers Life Insurance Company125,442$2.41M0.0%-31.9%0.079%
5/16/2026 Quantinno Capital Management LP30,170$579K0.0%+14.7%0.019%
5/16/2026 Masters Capital Management LLC600,000$11.52M0.4%-40.0%0.378%
5/14/2026 Sei Investments Co.52,235$1.00M0.0%N/A0.033%
5/13/2026 Cetera Investment Advisers11,059$212K0.0%N/A0.007%
5/8/2026 PNC Financial Services Group Inc.9,220$177K0.0%+8.7%0.006%
5/7/2026 Dimensional Fund Advisors LP2,692,175$51.69M0.0%+13.4%1.697%
5/7/2026 KBC Group NV4,943$95K0.0%-21.1%0.003%
5/5/2026 D.A. Davidson & CO.110,235$2.12M0.0%+3.1%0.069%
5/5/2026 Bank of New York Mellon Corp768,039$14.75M0.0%+0.8%0.484%
5/4/2026 Principal Financial Group Inc.1,478,486$28.39M0.0%-3.0%0.932%
5/4/2026 Teachers Retirement System of The State of Kentucky166,181$3.19M0.0%+8.1%0.105%
5/1/2026 Fifth Third Bancorp2,847$55K0.0%N/A0.002%
5/1/2026 Candriam S.C.A.1,099,845$21.12M0.1%-5.7%0.693%
4/27/2026 Y Intercept Hong Kong Ltd78,007$1.50M0.0%-16.6%0.049%
4/22/2026 Pictet Asset Management Holding SA2,558,865$48.44M0.1%+92.5%1.614%
4/22/2026 Sterling Capital Management LLC4,493$86K0.0%-37.9%0.003%
4/21/2026 Contravisory Investment Management Inc.14,451$277K0.1%N/A0.009%
4/20/2026 Breakwater Capital Group15,586$299K0.0%-4.8%0.010%
4/16/2026 SG Americas Securities LLC46,642$896K0.0%-68.8%0.029%
2/27/2026 Groupama Asset Managment151,591$2.50M0.0%+11.7%0.103%
2/19/2026 T. Rowe Price Investment Management Inc.7,254,132$119.77M0.1%+28.7%4.946%
2/19/2026 Invesco Ltd.291,936$4.82M0.0%+17.0%0.199%
2/18/2026 Voloridge Investment Management LLC591,461$9.77M0.0%-36.8%0.403%
2/18/2026 Vestal Point Capital LP465,000$7.68M0.3%N/A0.317%
2/18/2026 Virtus Investment Advisers LLC14,795$244K0.1%+94.1%0.010%
2/18/2026 Wellington Management Group LLP54,543$901K0.0%-7.9%0.037%
2/18/2026 Susquehanna Portfolio Strategies LLC167,713$2.77M0.0%N/A0.114%
2/18/2026 Tudor Investment Corp ET AL53,683$886K0.0%-4.8%0.037%
2/18/2026 Millennium Management LLC369,767$6.11M0.0%-71.7%0.252%
2/18/2026 Man Group plc48,994$809K0.0%N/A0.033%
2/18/2026 Ishara Investments LP70,000$1.16M1.3%N/A0.048%
2/18/2026 Casdin Capital LLC1,840,000$30.38M1.9%+106.7%1.255%
2/18/2026 Clough Capital Partners L P51,830$856K0.1%N/A0.035%
2/17/2026 Guggenheim Capital LLC12,468$206K0.0%-74.8%0.009%
2/17/2026 ADAR1 Capital Management LLC52,116$860K0.1%+1.2%0.036%
2/17/2026 Burkehill Global Management LP200,000$3.30M0.2%N/A0.136%
2/17/2026 AQR Capital Management LLC38,438$635K0.0%+59.2%0.026%
2/17/2026 Trexquant Investment LP209,609$3.46M0.0%-51.3%0.143%
2/17/2026 Jump Financial LLC40,608$670K0.0%-75.6%0.028%
2/17/2026 Price T Rowe Associates Inc. MD3,915,951$64.65M0.0%-14.3%2.670%
2/17/2026 T. Rowe Price Investment Management Inc.1,245,994$20.57M0.0%-77.9%0.850%
2/17/2026 Ghisallo Capital Management LLC100,000$1.65M0.1%N/A0.068%
2/17/2026 State of Wisconsin Investment Board73,581$1.22M0.0%-8.2%0.050%
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2/17/2026 ExodusPoint Capital Management LP1,023,253$16.89M0.1%N/A0.698%
2/17/2026 Royal Bank of Canada11,335$187K0.0%-97.0%0.008%
2/17/2026 Graham Capital Management L.P.18,121$299K0.0%-53.9%0.012%
2/17/2026 Persistent Asset Partners Ltd5,670$94K0.0%N/A0.004%
2/17/2026 Aster Capital Management DIFC Ltd3,451$57K0.0%N/A0.002%
2/17/2026 Temasek Holdings Private Ltd7,012,974$115.78M0.4%+30.9%4.782%
2/16/2026 Barclays PLC407,359$6.73M0.0%-6.8%0.278%
2/13/2026 Marshall Wace LLP763,892$12.61M0.0%-2.9%0.521%
2/13/2026 The Manufacturers Life Insurance Company 184,238$3.03M0.0%-10.5%0.126%
2/13/2026 Segall Bryant & Hamill LLC537,000$8.87M0.1%+4.7%0.366%


DNLI Institutional Ownership - Frequently Asked Questions

During the previous two years, 258 institutional investors and hedge funds held shares of Denali Therapeutics. The most heavily invested institutionals were BlackRock Inc. ($360.76M), Vanguard Group Inc. ($215.59M), Baillie Gifford & Co. ($203.25M), FMR LLC ($163.44M), T. Rowe Price Investment Management Inc. ($119.77M), Temasek Holdings Private Ltd ($115.78M), and State Street Corp ($103.41M).Learn more on Denali Therapeutics' institutional investors.

92.92% of Denali Therapeutics' stock is owned by institutional investors. Learn more on DNLI's institutional investor holdings.

Of the 231 institutional investors that purchased Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: BlackRock Inc. ($14.03M), Norges Bank ($10.13M), FMR LLC ($7.78M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($4.64M), California State Teachers Retirement System ($3.79M), Holocene Advisors LP ($3.17M), and ADAR1 Capital Management LLC ($2.86M).

Institutional investors have bought a total of 58,500,371 shares in the last 24 months. This purchase volume represents approximately $1.17B in transactions.

Of the 68 institutional investors that sold Denali Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: T. Rowe Price Investment Management Inc. ($4.39M), UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC ($2.55M), Alyeska Investment Group L.P. ($1.72M), Capital Research Global Investors ($1.03M), Millennium Management LLC ($937.40K), Price T Rowe Associates Inc. MD ($652.42K), and Marshall Wace LLP ($641.36K).

Institutional investors have sold a total of 15,295,150 shares in the last 24 months. This volume of shares sold represents approximately $277.22M in transactions.


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Institutional ownership data for NASDAQ:DNLI is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 8/27/2026. New 13F filings are added each quarter as they're published.
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