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Denali Therapeutics (DNLI) Short Interest Ratio & Short Volume

Denali Therapeutics logo
$21.40 -0.17 (-0.79%)
Closing price 04:00 PM Eastern
Extended Trading
$21.40 0.00 (-0.02%)
As of 05:28 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Denali Therapeutics Short Interest Overview

As of August 31, 2026, Denali Therapeutics (DNLI) had a short interest of 16.64 million shares sold short, representing 11.53% of the public float. This marks a -7.33% decrease in short interest since the prior report. The short interest ratio (days to cover) is 17.5, meaning it would take 17.5 days of the average trading volume of 1.70 million shares to cover all short positions.

Current Short Interest
16,642,362 shares
Previous Short Interest
17,959,465 shares
Change Vs. Previous Month
-7.33%
Dollar Volume Sold Short
$395.42 million
Short Interest Ratio
17.5 Days to Cover
Last Record Date
August 31, 2026
Outstanding Shares
159,850,000 shares
Short Percent of Float
11.53%
Today's Trading Volume
938,554 shares
Average Trading Volume
1,704,227 shares
Today's Volume Vs. Average
55%
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Short Interest ChartDays to Cover ChartShort Percent of Float Chart

DNLI Short Interest Over Time

DNLI Days to Cover Over Time

DNLI Percentage of Float Shorted Over Time

Denali Therapeutics Tesla Short Interest History & Recent Changes

Export
Report DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date
8/31/202616,642,362 shares $395.42 million -7.3%11.5%17.5 $23.76
8/14/202617,959,465 shares $438.21 million +3.0%12.4%12.41 $24.40
7/31/202617,434,654 shares $401.35 million +8.7%12.2%12.12 $23.02
7/15/202616,035,916 shares $369.15 million +0.5%11.2%8.39 $23.02
6/30/202615,949,089 shares $410.21 million +3.5%11.5%6.95 $25.72
6/15/202615,407,744 shares $342.36 million +2.8%11.1%8.43 $22.22
5/29/202614,990,471 shares $315.40 million +6.9%10.8%8.02 $21.04
5/15/202614,026,925 shares $261.18 million -5.3%10.1%7.51 $18.62
4/30/202614,813,936 shares $277.32 million -3.1%10.7%9.95 $18.72
4/15/202615,284,401 shares $331.37 million -0.9%11.0%11.04 $21.68
3/31/202615,421,152 shares $296.09 million +8.2%10.8%6.67 $19.20
3/13/202614,258,580 shares $293.30 million -0.4%10.3%9.53 $20.57
2/27/202614,319,419 shares $303.29 million +5.3%10.3%9.03 $21.18
2/13/202613,594,971 shares $255.18 million +0.3%9.8%8.71 $18.77
1/30/202613,558,718 shares $294.77 million -8.8%10.6%7.02 $21.74
1/15/202614,858,586 shares $279.04 million +2.1%11.6%9.68 $18.78
12/31/202514,560,677 shares $240.40 million +11.2%11.3%12.46 $16.51
12/15/202513,092,563 shares $227.03 million +0.9%10.2%6.15 $17.34
11/28/202512,977,218 shares $255.46 million -7.4%10.1%10.05 $19.69
11/14/202514,017,386 shares $244.46 million +6.9%10.9%9.06 $17.44
10/31/202513,110,288 shares $213.44 million -9.8%10.2%8.85 $16.28
10/15/202514,530,000 shares $236.98 million +2.7%11.1%7.5 $16.31
9/30/202514,150,000 shares $205.46 million +8.2%10.8%7.4 $14.52
9/15/202513,080,000 shares $172.13 million -4.9%10.0%7 $13.16
8/31/202513,750,000 shares $209.96 million +2.1%10.9%7.9 $15.27
8/15/202513,470,000 shares $198.01 million +5.0%10.7%8.2 $14.70
7/31/202512,830,000 shares $177.44 million +1.2%10.2%8.3 $13.83
7/15/202512,680,000 shares $179.68 million +1.8%10.1%8.5 $14.17
6/30/202512,460,000 shares $174.32 million +4.3%9.9%8.3 $13.99
6/15/202511,950,000 shares $173.87 million -2.2%9.5%7.8 $14.55
5/31/202512,220,000 shares $161.06 million +1.0%9.7%8.2 $13.18
5/15/202512,100,000 shares $171.34 million +3.1%9.6%8.5 $14.16
4/30/202511,740,000 shares $195.47 million -9.7%9.3%8.5 $16.65
4/15/202513,000,000 shares $171.21 million +13.6%10.3%10.1 $13.17
3/31/202511,440,000 shares $155.58 million +8.9%9.1%9.1 $13.60
3/15/202510,510,000 shares $159.23 million +18.2%8.4%9.7 $15.15
2/28/20258,890,000 shares $147.22 million +2.3%7.1%8.5 $16.56
2/15/20258,690,000 shares $185.71 million +12.3%7.0%9.4 $21.37
1/31/20257,740,000 shares $180.34 million -2.9%6.2%8 $23.30
1/15/20257,970,000 shares $171.36 million +1.7%6.4%8.6 $21.50
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12/31/20247,840,000 shares $159.78 million +5.1%6.3%9 $20.38
12/15/20247,460,000 shares $171.36 million +1.2%6.0%8.9 $22.97
11/30/20247,370,000 shares $184.25 million +3.8%5.9%8.5 $25.00
11/15/20247,100,000 shares $177.86 million -4.4%5.7%8 $25.05
10/31/20247,430,000 shares $192.88 million -3.9%5.9%8.9 $25.96
10/15/20247,730,000 shares $207.55 million -0.1%6.5%9 $26.85
9/30/20247,740,000 shares $225.47 million -17.7%6.5%8.1 $29.13
9/15/20249,400,000 shares $289.24 million +4.3%7.9%9 $30.77
8/31/20249,010,000 shares $220.20 million +7.8%7.6%8.2 $24.44
8/15/20248,360,000 shares $197.88 million +16.3%7.0%7.3 $23.67
7/31/20247,190,000 shares $175.22 million +1.4%6.1%6.1 $24.37
7/15/20247,090,000 shares $165.41 million -4.6%6.1%5.8 $23.33
6/30/20247,430,000 shares $172.52 million -16.1%6.3%6.1 $23.22
6/15/20248,860,000 shares $183.67 million -5.0%7.6%7.7 $20.73
5/31/20249,330,000 shares $173.16 million -1.7%8.0%8.6 $18.56
5/15/20249,490,000 shares $197.96 million -9.6%8.1%8 $20.86
4/30/202410,500,000 shares $162.12 million +9.6%8.2%8.3 $15.44
4/15/20249,580,000 shares $170.91 million +1.8%8.3%7.9 $17.84
3/31/20249,410,000 shares $193.09 million +12.3%8.4%8 $20.52
3/15/20248,380,000 shares $168.69 million -5.5%7.5%7.2 $20.13
2/29/20248,870,000 shares $175.45 million -18.0%7.9%7.3 $19.78
2/15/202410,820,000 shares $198.66 million +10.0%9.7%9.5 $18.36
1/31/20249,840,000 shares $157.54 million -0.4%9.0%9.4 $16.01
1/15/20249,880,000 shares $183.18 million +2.6%8.7%9.5 $18.54
12/31/20239,630,000 shares $206.66 million +5.4%8.5%9.7 $21.46
12/15/20239,140,000 shares $209.67 million +0.2%8.0%9.2 $22.94
11/30/20239,120,000 shares $168.90 million -4.6%8.0%10.1 $18.52
11/15/20239,560,000 shares $176.67 million -10.9%8.4%11.2 $18.48
10/31/202310,730,000 shares $202.05 million +12.7%9.5%13.9 $18.83
10/15/20239,520,000 shares $197.64 million -2.0%8.8%13.7 $20.76
9/30/20239,710,000 shares $200.32 million +3.6%8.9%15.1 $20.63
9/15/20239,370,000 shares $220.66 million +3.1%8.6%15.4 $23.55
8/31/20239,090,000 shares $209.89 million -1.5%8.3%14 $23.09
8/15/20239,230,000 shares $224.20 million +6.2%8.5%13.9 $24.29
7/31/20238,690,000 shares $247.06 million +6.4%8.1%12.6 $28.43
7/15/20238,170,000 shares $239.63 million +1.4%7.7%11.4 $29.33
6/30/20238,060,000 shares $237.85 million -7.7%7.5%10.5 $29.51
6/15/20238,730,000 shares $283.64 million +8.0%8.2%11.1 $32.49
5/31/20238,080,000 shares $244.18 million -6.4%7.6%10.8 $30.22
5/15/20238,630,000 shares $276.33 million No Change8.1%11.4 $32.02
10/31/20226,980,000 shares $200.19 million -4.3%6.2%8.4 $28.68
10/15/20227,290,000 shares $237.44 million +2.7%6.6%9 $32.57
9/30/20227,100,000 shares $217.90 million +6.6%7.0%10.5 $30.69
9/15/20226,660,000 shares $207.06 million +0.2%6.5%10.5 $31.09
8/31/20226,650,000 shares $184.01 million +2.0%6.5%9.9 $27.67
8/15/20226,520,000 shares $245.22 million -11.5%6.4%10.4 $37.61
7/31/20227,370,000 shares $250.73 million -2.5%7.6%11.2 $34.02
7/15/20227,560,000 shares $262.33 million -0.4%7.8%12 $34.70
6/30/20227,590,000 shares $223.37 million -3.2%7.8%12.5 $29.43
6/15/20227,840,000 shares $177.03 million +0.5%8.1%13.4 $22.58
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5/31/20227,800,000 shares $189.46 million +5.4%8.0%14.7 $24.29
5/15/20227,400,000 shares $169.16 million +11.1%7.6%13.7 $22.86
4/30/20226,660,000 shares $158.51 million +1.1%6.9%12.8 $23.80
4/15/20226,590,000 shares $198.42 million -2.2%6.8%12.9 $30.11
3/31/20226,740,000 shares $216.83 million +0.2%N/A11.5 $32.17
3/15/20226,730,000 shares $199.28 million +3.5%6.9%11.5 $29.61
2/28/20226,500,000 shares $211.64 million -2.1%7.8%11.1 $32.56
2/15/20226,640,000 shares $236.65 million +20.7%8.0%11.3 $35.64
1/31/20225,500,000 shares $188.21 million +1.7%6.7%9.6 $34.22
1/15/20225,410,000 shares $188.48 million +2.3%6.6%10 $34.84
12/31/20215,290,000 shares $235.93 million -7.5%6.5%11.2 $44.60
12/15/20215,720,000 shares $260.32 million +9.8%7.0%11.7 $45.51
11/30/20215,210,000 shares $241.01 million -4.6%6.4%10.4 $46.26
11/15/20215,460,000 shares $273.66 million -3.4%6.7%11.3 $50.12
10/29/20215,650,000 shares $273.18 million -6.6%6.9%12.1 $48.35
10/15/20216,050,000 shares $275.64 million -6.2%7.4%12.8 $45.56
9/30/20216,450,000 shares $325.40 million +10.6%7.8%12.2 $50.45
9/15/20215,830,000 shares $306.83 million +1.0%7.1%9.9 $52.63

DNLI Short Interest - Frequently Asked Questions

Short interest is the volume of Denali Therapeutics shares that have been sold short but have not yet been closed out or covered. As of August 14th, traders have sold 17,959,465 shares of DNLI short. 12.44% of Denali Therapeutics' shares are currently sold short. Learn More on Denali Therapeutics' current short interest.

The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. DNLI shares currently have a short interest ratio of 12.4. Learn More on Denali Therapeutics's short interest ratio.

Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 12.44% of Denali Therapeutics' floating shares are currently sold short.

Denali Therapeutics saw a increase in short interest in August. As of August 14th, there was short interest totaling 17,959,465 shares, an increase of 3.0% from the previous total of 17,434,654 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment.

12.44% of Denali Therapeutics' shares are currently sold short. Here is how the short interest of companies in the industry of "biotechnology" compare to Denali Therapeutics: Beam Therapeutics Inc. (24.53%), Summit Therapeutics PLC (28.44%), BioMarin Pharmaceutical Inc. (5.31%), Halozyme Therapeutics, Inc. (13.23%), Madrigal Pharmaceuticals, Inc. (10.64%), Arrowhead Pharmaceuticals, Inc. (6.78%), Krystal Biotech, Inc. (12.46%), Abivax SA Sponsored ADR (6.88%), Praxis Precision Medicines, Inc. (13.72%), Kymera Therapeutics, Inc. (14.86%),

As of the most recent reporting period, the following stocks had the largest short interest positions: SPDR S&P 500 ETF Trust ($71.57 billion), Invesco QQQ ($46.97 billion), iShares Russell 2000 ETF ($24.02 billion), Nebius Group N.V. ($15.37 billion), Sandisk Corporation ($12.60 billion), SPDR S&P Biotech ETF ($12.14 billion), Western Digital Corporation ($10.32 billion), iShares 20+ Year Treasury Bond ETF ($8.38 billion), VanEck Semiconductor ETF ($7.62 billion), and iShares iBoxx $ High Yield Corporate Bond ETF ($7.07 billion). View all of the most shorted stocks.

Short selling DNLI is an investing strategy that aims to generate trading profit from Denali Therapeutics as its price is falling. DNLI shares are trading down $0.17 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit.

A short squeeze for Denali Therapeutics occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of DNLI, which in turn drives the price of the stock up even further.

Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including DNLI, twice per month. The most recent reporting period available is August, 14 2026.

Understanding short interest metrics can help you assess how traders are positioning around a stock like DNLI:

  • Shares Sold Short: The total number of shares that have been sold by short sellers but have not yet been covered or closed out. A high number may indicate bearish sentiment.
  • Short Float: The percentage of a company’s publicly available shares (or "float") that are sold short. A higher short float suggests a greater portion of the stock is being bet against.
  • Days to Cover (Short Interest Ratio): This estimates how many days it would take short sellers to cover their positions, based on average daily trading volume. Higher values can signal potential for a short squeeze if buying pressure increases.

These metrics are often used by traders to gauge sentiment, volatility risk, and the potential for price movements based on short covering activity.


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Short Interest Tools

Short interest data for NASDAQ:DNLI is sourced from the Financial Industry Regulatory Authority (FINRA), with the most recent report published on 9/10/2026. FINRA publishes updated short interest twice a month.
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