Praxis Precision Medicines (PRAX) Institutional Ownership

$344.75 -23.10 (-6.28%)

As of 08/28/2026 04:00 PM Eastern

Current Institutional Ownership Percentage: 67.84%
Number of Institutional Buyers (last 12 months): 161
Total Institutional Inflows (last 12 months): $5.23B

Number of Institutional Sellers (last 12 months): 50
Total Institutional Outflows (last 12 months): $1.01B

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PRAX Institutional Buying and Selling by Quarter

Praxis Precision Medicines Major Shareholders & Ownership History

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Reporting Date	Major Shareholder Name	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
8/25/2026	VIRGINIA RETIREMENT SYSTEMS ET Al	8,060	$2.70M	0.0%	N/A	0.029%
8/24/2026	California State Teachers Retirement System	8,906,418	$2.98B	0.0%	+32,314.1%	31.900%
8/23/2026	Readystate Asset Management LP	10,548	$3.53M	0.1%	N/A	0.038%
8/22/2026	Seven Fleet Capital Management LP	7,540	$2.52M	0.4%	N/A	0.027%
8/21/2026	Nykredit A S	779	$261K	0.0%	N/A	0.003%
8/21/2026	Velan Capital Investment Management LP	88,781	$29.72M	18.0%	-11.9%	0.318%
8/19/2026	Wellington Management Group LLP	125,867	$42.14M	0.0%	-27.8%	0.451%
8/6/2026	Bank of New York Mellon Corp	85,376	$28.58M	0.0%	N/A	0.306%
7/10/2026	Handelsbanken Fonder AB	9,840	$3.29M	0.0%	N/A	0.035%
7/7/2026	GAMMA Investing LLC	332	$111K	0.0%	+10.3%	0.001%
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6/3/2026	Parallel Advisors LLC	124	$40K	0.0%	+3,000.0%	0.000%
5/29/2026	Perceptive Advisors LLC	2,035,986	$655.97M	12.8%	+2.0%	7.303%
5/26/2026	Glenmede Trust Co. NA	3,410	$1.10M	0.0%	-45.8%	0.012%
5/21/2026	CTC Alternative Strategies Ltd.	925	$298K	0.7%	N/A	0.003%
5/20/2026	Vivo Capital LLC	338,895	$109.19M	9.1%	+3.0%	1.216%
5/19/2026	Bank of America Corp DE	534,604	$172.24M	0.0%	+2.3%	1.918%
5/19/2026	Stempoint Capital LP	56,267	$18.13M	3.5%	+167.1%	0.202%
5/19/2026	Janus Henderson Group PLC	3,458,863	$1.11B	0.5%	+6.8%	12.406%
5/19/2026	Ally Bridge Group NY LLC	32,810	$10.57M	8.5%	+65.0%	0.118%
5/18/2026	Amundi	1,802	$581K	0.0%	+128.1%	0.006%
5/18/2026	California State Teachers Retirement System	27,477	$8.85M	0.0%	+39.7%	0.099%
5/18/2026	Royal Bank of Canada	4,133	$1.33M	0.0%	+22.4%	0.015%
5/18/2026	Exome Asset Management LLC	45,469	$14.65M	7.6%	-21.8%	0.163%
5/16/2026	The Manufacturers Life Insurance Company	30,093	$9.70M	0.0%	-9.6%	0.108%
5/16/2026	Quantinno Capital Management LP	3,320	$1.07M	0.0%	+21.9%	0.012%
5/16/2026	SummitTX Capital L.P.	36,838	$11.87M	0.4%	-11.5%	0.132%
5/16/2026	ABS Direct Equity Fund LLC	400	$135K	0.1%	N/A	0.001%
5/16/2026	Orbimed Advisors LLC	172,500	$55.58M	1.0%	+82.5%	0.619%
5/15/2026	Affinity Asset Advisors LLC	170,000	$54.77M	2.8%	-8.1%	0.610%
5/14/2026	Sei Investments Co.	29,525	$9.51M	0.0%	+86.9%	0.106%
5/13/2026	First Trust Advisors LP	33,335	$10.74M	0.0%	-62.4%	0.120%
5/8/2026	PNC Financial Services Group Inc.	953	$307K	0.0%	+33.5%	0.003%
5/7/2026	Carl P. Sherr & Co. LLC	972	$313K	0.1%	+8.4%	0.003%
5/7/2026	Dimensional Fund Advisors LP	31,161	$10.04M	0.0%	+32.4%	0.112%
5/7/2026	Parallel Advisors LLC	124	$40K	0.0%	+3,000.0%	0.000%
5/7/2026	KBC Group NV	715	$230K	0.0%	+5.8%	0.003%
5/7/2026	Swiss National Bank	46,700	$15.05M	0.0%	+15.3%	0.168%
5/6/2026	California Public Employees Retirement System	42,163	$13.58M	0.0%	N/A	0.151%
5/6/2026	Allspring Global Investments Holdings LLC	8,536	$2.73M	0.0%	+392.8%	0.031%
5/5/2026	Bank of New York Mellon Corp	87,047	$28.05M	0.0%	+11.7%	0.313%
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5/4/2026	Principal Financial Group Inc.	1,153	$371K	0.0%	+15.9%	0.004%
5/4/2026	Chicago Partners Investment Group LLC	833	$281K	0.0%	N/A	0.003%
5/1/2026	Fifth Third Bancorp	3,589	$1.16M	0.0%	N/A	0.013%
5/1/2026	Candriam S.C.A.	63,628	$20.50M	0.1%	-42.5%	0.228%
4/30/2026	Hsbc Holdings PLC	1,634	$518K	0.0%	+98.1%	0.006%
4/28/2026	Abel Hall LLC	1,392	$448K	0.1%	+34.9%	0.005%
4/25/2026	Strs Ohio	3,600	$1.16M	0.0%	+12.5%	0.013%
4/22/2026	Pictet Asset Management Holding SA	286,644	$91.43M	0.1%	+19.1%	1.029%
4/22/2026	Sterling Capital Management LLC	804	$259K	0.0%	-33.6%	0.003%
4/21/2026	Pinnacle Wealth Management Advisory Group LLC	744	$240K	0.0%	N/A	0.003%
4/16/2026	SG Americas Securities LLC	852	$275K	0.0%	-91.5%	0.003%
3/20/2026	Hsbc Holdings PLC	825	$244K	0.0%	-92.6%	0.003%
2/26/2026	Seven Fleet Capital Management LP	2,700	$796K	0.6%	N/A	0.010%
2/19/2026	T. Rowe Price Investment Management Inc.	276,392	$81.46M	0.1%	N/A	1.097%
2/19/2026	Invesco Ltd.	77,088	$22.72M	0.0%	+269.4%	0.306%
2/18/2026	Mercer Global Advisors Inc. ADV	1,212	$357K	0.0%	N/A	0.005%
2/18/2026	Mackenzie Financial Corp	1,399	$415K	0.0%	N/A	0.006%
2/18/2026	Coastal Bridge Advisors LLC	4,154	$1.22M	0.1%	+8.0%	0.016%
2/18/2026	KVP Capital Advisors LP	42,900	$12.64M	12.2%	N/A	0.170%
2/18/2026	Ikarian Capital LLC	86,581	$25.52M	2.0%	-32.7%	0.344%
2/18/2026	Virtus Investment Advisers LLC	989	$291K	0.1%	-60.9%	0.004%
2/18/2026	Wellington Management Group LLP	176,562	$52.04M	0.0%	+188.3%	0.701%
2/18/2026	SummitTX Capital L.P.	41,629	$12.27M	0.4%	+19.2%	0.165%
2/18/2026	Readystate Asset Management LP	36,792	$10.84M	0.4%	-66.3%	0.146%
2/18/2026	Orbimed Advisors LLC	94,500	$27.85M	0.6%	N/A	0.375%
2/18/2026	Perceptive Advisors LLC	1,995,986	$588.30M	10.5%	+27.6%	7.924%
2/18/2026	Man Group plc	21,170	$6.24M	0.0%	N/A	0.084%
2/18/2026	Ishara Investments LP	40,000	$11.79M	13.6%	N/A	0.159%
2/18/2026	Janus Henderson Group PLC	3,240,086	$954.83M	0.4%	+17.2%	12.863%
2/18/2026	Cormorant Asset Management LP	950,000	$280.00M	12.9%	-5.0%	3.771%
2/18/2026	Artia Global Partners LP	2,500	$737K	0.1%	N/A	0.010%
2/18/2026	Baker BROS. Advisors LP	1,126,488	$332.02M	1.9%	+63.4%	4.472%
2/18/2026	Boothbay Fund Management LLC	20,974	$6.18M	0.1%	-78.2%	0.083%
2/18/2026	ACT Capital Management LLC	700	$206K	0.2%	N/A	0.003%
2/17/2026	Logos Global Management LP	375,000	$110.53M	6.7%	+200.0%	1.489%
2/17/2026	ADAR1 Capital Management LLC	1,500	$442K	0.0%	N/A	0.006%
2/17/2026	Burkehill Global Management LP	25,000	$7.37M	0.5%	N/A	0.099%
2/17/2026	AQR Capital Management LLC	28,828	$8.50M	0.0%	+31.6%	0.114%
2/17/2026	Abel Hall LLC	1,032	$304K	0.1%	N/A	0.004%
2/17/2026	Ally Bridge Group NY LLC	19,882	$5.86M	6.1%	-80.1%	0.079%
2/17/2026	RA Capital Management L.P.	373,787	$110.17M	1.1%	N/A	1.484%
2/17/2026	ArrowMark Colorado Holdings LLC	30,000	$8.84M	0.2%	N/A	0.119%
2/17/2026	Trexquant Investment LP	8,331	$2.46M	0.0%	-6.4%	0.033%
2/17/2026	Amundi	790	$233K	0.0%	N/A	0.003%
2/17/2026	Orbis Allan Gray Ltd	1,255,162	$369.95M	1.6%	N/A	4.983%
2/17/2026	Price T Rowe Associates Inc. MD	785,987	$231.66M	0.0%	-21.7%	3.120%
2/17/2026	T. Rowe Price Investment Management Inc.	18,018	$5.31M	0.0%	N/A	0.072%
2/17/2026	Integral Health Asset Management LLC	40,000	$11.79M	0.6%	N/A	0.159%
2/17/2026	Adage Capital Partners GP L.L.C.	965,313	$284.52M	0.4%	-59.3%	3.832%
2/17/2026	California State Teachers Retirement System	19,671	$5.80M	0.0%	+5.9%	0.078%
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2/17/2026	Russell Investments Group Ltd.	20,612	$6.08M	0.0%	+368.0%	0.082%
2/17/2026	B Group Inc.	33,237	$9.80M	7.2%	+5.5%	0.132%
2/17/2026	Atom Investors LP	16,487	$4.86M	0.4%	N/A	0.065%
2/17/2026	State of Wisconsin Investment Board	15,231	$4.49M	0.0%	+68.6%	0.060%
2/17/2026	Royal Bank of Canada	3,378	$995K	0.0%	-14.6%	0.013%
2/17/2026	Opal Capital LLC	996	$318K	0.1%	N/A	0.004%
2/16/2026	Squarepoint Ops LLC	1,890	$557K	0.0%	N/A	0.008%
2/16/2026	Sofinnova Investments Inc.	125,722	$37.06M	1.5%	-27.3%	0.499%
2/16/2026	Public Employees Retirement Association of Colorado	2,390	$704K	0.0%	+1,001.4%	0.009%
2/16/2026	MML Investors Services LLC	864	$255K	0.0%	N/A	0.003%

PRAX Institutional Ownership - Frequently Asked Questions

During the previous two years, 233 institutional investors and hedge funds held shares of Praxis Precision Medicines. The most heavily invested institutionals were California State Teachers Retirement System ($2.98B), Janus Henderson Group PLC ($1.11B), Perceptive Advisors LLC ($655.97M), Vanguard Group Inc. ($430.60M), Orbis Allan Gray Ltd ($369.95M), Baker BROS. Advisors LP ($332.02M), and Adage Capital Partners GP L.L.C. ($284.52M).Learn more on Praxis Precision Medicines' institutional investors.

67.84% of Praxis Precision Medicines' stock is owned by institutional investors. Learn more on PRAX's institutional investor holdings.

Of the 206 institutional investors that purchased Praxis Precision Medicines' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: California State Teachers Retirement System ($8.89M), Adage Capital Partners GP L.L.C. ($1.37M), Orbis Allan Gray Ltd ($1.26M), Janus Henderson Group PLC ($1.24M), Assenagon Asset Management S.A. ($645.88K), Baker BROS. Advisors LP ($637K), and Woodline Partners LP ($547.44K).

Institutional investors have bought a total of 17,639,826 shares in the last 24 months. This purchase volume represents approximately $5.23B in transactions.

Of the 50 institutional investors that sold Praxis Precision Medicines' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Adage Capital Partners GP L.L.C. ($1.41M), Soleus Capital Management L.P. ($496.20K), CIBC Asset Management Inc ($387.86K), Price T Rowe Associates Inc. MD ($217.50K), Assenagon Asset Management S.A. ($195.51K), Ally Bridge Group NY LLC ($80.12K), and Boothbay Fund Management LLC ($75.09K).

Institutional investors have sold a total of 3,737,287 shares in the last 24 months. This volume of shares sold represents approximately $1.01B in transactions.

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Institutional ownership data for NASDAQ:PRAX is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 8/25/2026. New 13F filings are added each quarter as they're published.

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Praxis Precision Medicines (PRAX) Institutional Ownership

PRAX Institutional Buying and Selling by Quarter

Praxis Precision Medicines Major Shareholders & Ownership History

PRAX Institutional Ownership - Frequently Asked Questions

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Praxis Precision Medicines (PRAX) Institutional Ownership

Institutional Ownership Changes (13F Filings) for Praxis Precision Medicines (NASDAQ:PRAX)

PRAX Institutional Buying and Selling by Quarter

Praxis Precision Medicines Major Shareholders & Ownership History

PRAX Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of PRAX shares?

What percentage of Praxis Precision Medicines' stock is owned by institutional investors?

Which institutional investors have been buying Praxis Precision Medicines' stock?

How much institutional buying is happening at Praxis Precision Medicines?

Which of Praxis Precision Medicines' major shareholders have been selling company stock?

How much institutional selling is happening at Praxis Precision Medicines?

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