Soleus Capital Management, L.P. Top Holdings and 13F Report (2026)

About Soleus Capital Management, L.P.

Investment Activity

Soleus Capital Management, L.P. has $2.47 billion in total holdings as of March 31, 2026.
Soleus Capital Management, L.P. owns shares of 93 different stocks, but just 29 companies or ETFs make up 80% of its holdings.
Approximately 33.95% of the portfolio was purchased this quarter.
About 43.28% of the portfolio was sold this quarter.
This quarter, Soleus Capital Management, L.P. has purchased 95 new stocks and bought additional shares in 29 stocks.
Soleus Capital Management, L.P. sold shares of 30 stocks and completely divested from 27 stocks this quarter.

Largest Holdings

Krystal Biotech: $297,865,434
Celcuity: $146,598,905
TG Therapeutics: $133,853,977
Insulet: $118,035,000
NovoCure: $114,367,062

Largest New Holdings this Quarter

45579U109 - INDIVIOR PHARMACEUTICALS INC: $38,831,520 Holding
74340E103 - Progyny: $35,097,660 Holding
58933Y105 - Merck & Co., Inc.: $24,418,870 Holding
G4705A100 - Icon: $21,246,720 Holding
21077P108 - Context Therapeutics: $18,243,429 Holding

Largest Purchases this Quarter

Insulet: 412,500 shares (about $86.56M)
United Therapeutics: 127,187 shares (about $75.42M)
Vericel: 1,785,079 shares (about $57.43M)
Krystal Biotech: 212,028 shares (about $54.77M)
INDIVIOR PHARMACEUTICALS INC: 1,274,000 shares (about $38.83M)

Largest Sales this Quarter

DexCom: 1,157,094 shares (about $72.67M)
Celcuity: 523,880 shares (about $59.80M)
BioMarin Pharmaceutical: 669,428 shares (about $37.82M)
Enliven Therapeutics: 794,131 shares (about $31.13M)
Twist Bioscience: 635,173 shares (about $30.18M)

Sector Allocation Over Time

Selling

Neutral

Buying

Latest 13F Holdings and Changes Since Previous Quarterly Filing

Issuer Name	Holdings Value	Approximate Purchase/Sale	Change in Shares	Shares Held	% of Portfolio	Sector
KRYS Krystal Biotech	$297,865,434	$54,771,073 â–²	22.5%	1,153,087	12.1%	Medical
CELC Celcuity	$146,598,905	$59,795,663 â–¼	-29.0%	1,284,378	5.9%	Medical
TGTX TG Therapeutics	$133,853,977	$29,566,033 â–²	28.4%	4,029,319	5.4%	Medical
PODD Insulet	$118,035,000	$86,559,000 â–²	275.0%	562,500	4.8%	Medical
NVCR NovoCure	$114,367,062	$21,382,813 â–²	23.0%	10,492,391	4.6%	Medical
UTHR United Therapeutics	$110,998,147	$75,419,347 â–²	212.0%	187,187	4.5%	Medical
PRAXIS PRECISION MEDICINES I	$106,489,272	$10,454,743 â–¼	-8.9%	330,517	4.3%	COM NEW
VCEL Vericel	$82,003,871	$57,425,991 â–²	233.6%	2,549,079	3.3%	Medical
ALKS Alkermes	$69,689,751	$22,930,960 â–²	49.0%	1,970,864	2.8%	Medical
ANIP ANI Pharmaceuticals	$63,076,687	$25,684,600 â–²	68.7%	820,243	2.6%	Medical
GMED Globus Medical	$62,850,877	$13,573,043 â–¼	-17.8%	729,467	2.5%	Medical
GERN Geron	$61,847,902	$27,145,802 â–²	78.2%	41,508,659	2.5%	Medical
TWST Twist Bioscience	$58,289,410	$30,183,421 â–¼	-34.1%	1,226,629	2.4%	Medical
EWTX Edgewise Therapeutics	$45,672,323	$17,007,323 â–²	59.3%	1,449,915	1.8%	Medical
BETA BIONICS INC	$43,632,100	$18,235,759 â–²	71.8%	4,354,501	1.8%	COM
ALNY Alnylam Pharmaceuticals	$43,559,036	$20,398,136 â–²	88.1%	131,650	1.8%	Medical
SNDX Syndax Pharmaceuticals	$40,340,571	$12,151,919 â–¼	-23.1%	1,726,908	1.6%	Medical
INDIVIOR PHARMACEUTICALS INC	$38,831,520	$38,831,520 â–²	New Holding	1,274,000	1.6%	COM
NPCE NeuroPace	$38,558,522	$3,011,337 â–²	8.5%	2,932,207	1.6%	Medical
LIVN LivaNova	$37,023,700	$953,400 â–²	2.6%	582,500	1.5%	Medical
MIRM Mirum Pharmaceuticals	$36,980,268	$16,010,193 â–¼	-30.2%	400,306	1.5%	Medical
BMRN BioMarin Pharmaceutical	$36,750,812	$37,815,987 â–¼	-50.7%	650,572	1.5%	Medical
PGNY Progyny	$35,097,660	$35,097,660 â–²	New Holding	2,067,000	1.4%	Medical
INSP Inspire Medical Systems	$29,725,502	$14,282,502 â–²	92.5%	576,299	1.2%	Medical
EDAP Edap Tms	$27,190,425		0.0%	7,309,254	1.1%	Medical
KINIKSA PHARMACEUTICALS INTL	$25,103,147	$3,160,903 â–¼	-11.2%	521,353	1.0%	ORD SHS CL A
MRK Merck & Co., Inc.	$24,418,870	$24,418,870 â–²	New Holding	203,000	1.0%	Medical
ORGO Organogenesis	$23,903,704	$237,000 â–²	1.0%	10,085,951	1.0%	Medical
NTRA Natera	$23,798,810	$19,799,010 â–²	495.0%	119,000	1.0%	Medical
AXGN AxoGen	$22,500,902	$17,482,204 â–¼	-43.7%	679,170	0.9%	Medical
PCVX Vaxcyte	$22,399,778	$12,986,772 â–¼	-36.7%	385,472	0.9%	Medical
ICLR Icon	$21,246,720	$21,246,720 â–²	New Holding	192,000	0.9%	Medical
PHVS Pharvaris	$19,832,969		0.0%	702,052	0.8%	Medical
CERS Cerus	$19,571,734	$12,291,734 â–²	168.8%	10,753,700	0.8%	Medical
TRVI Trevi Therapeutics	$19,326,600	$8,589,600 â–²	80.0%	1,620,000	0.8%	Medical
INHIBIKASE THERAPEUTICS INC	$18,270,000		0.0%	10,875,000	0.7%	COM NEW
CNTX Context Therapeutics	$18,243,429	$18,243,429 â–²	New Holding	6,963,141	0.7%	Medical
VIR Vir Biotechnology	$17,937,920	$17,937,920 â–²	New Holding	2,002,000	0.7%	Medical
XENE Xenon Pharmaceuticals	$16,979,800	$16,979,800 â–²	New Holding	292,000	0.7%	Medical
TVTX Travere Therapeutics	$16,221,660	$16,221,660 â–²	New Holding	546,000	0.7%	Medical
TNDM Tandem Diabetes Care	$15,010,110	$15,010,110 â–²	New Holding	783,000	0.6%	Medical
NRIX Nurix Therapeutics	$14,541,527	$4,359,081 â–¼	-23.1%	938,163	0.6%	Medical
URGN Urogen Pharma	$13,071,460	$10,374,460 â–²	384.7%	727,000	0.5%	Medical
SIONNA THERAPEUTICS INC	$11,766,415	$1,002,250 â–²	9.3%	293,500	0.5%	COM
CORT Corcept Therapeutics	$11,509,755	$11,509,755 â–²	New Holding	285,531	0.5%	Medical
JADE BIOSCIENCES INC	$11,194,253		0.0%	796,744	0.5%	COM NEW
VCYT Veracyte	$10,304,366	$9,982,266 â–²	3,099.1%	319,912	0.4%	Medical
IVVD Invivyd	$10,021,345		0.0%	7,708,727	0.4%	Medical
CCCC C4 Therapeutics	$10,004,367		0.0%	3,803,942	0.4%	Medical
KIDS OrthoPediatrics	$9,767,144	$1,428,300 â–²	17.1%	615,447	0.4%	Medical
RCUS Arcus Biosciences	$9,762,833	$5,616,000 â–¼	-36.5%	451,983	0.4%	Medical
TNGX Tango Therapeutics	$9,414,000	$9,204,800 â–²	4,400.0%	450,000	0.4%	Medical
EOLS Evolus	$9,228,430	$4,830,730 â–²	109.8%	2,245,360	0.4%	Medical
SOPH SOPHiA GENETICS	$9,157,500	$9,157,500 â–²	New Holding	1,850,000	0.4%	Medical
ELVN Enliven Therapeutics	$9,050,065	$31,129,936 â–¼	-77.5%	230,869	0.4%	Medical
INHIBRX BIOSCIENCES INC	$8,807,130	$7,126,380 â–²	424.0%	131,000	0.4%	COM
DXCM DexCom	$8,792,000	$72,665,503 â–¼	-89.2%	140,000	0.4%	Medical
SEPTERNA INC	$6,608,250	$2,604,083 â–¼	-28.3%	275,000	0.3%	COM
AVALO THERAPEUTICS INC	$6,598,732		0.0%	441,978	0.3%	COM NEW
BIODESIX INC	$6,040,686	$6,040,686 â–²	New Holding	416,599	0.2%	COM
RLMD Relmada Therapeutics	$5,861,058	$5,861,058 â–²	New Holding	842,106	0.2%	Medical
CGEM Cullinan Therapeutics	$5,828,942	$5,828,942 â–²	New Holding	410,200	0.2%	Medical
IMVT Immunovant	$5,713,200	$21,859,200 â–¼	-79.3%	230,000	0.2%	Medical
MBX BIOSCIENCES INC	$5,340,075	$6,865,589 â–¼	-56.2%	178,897	0.2%	COM
IMUX Immunic	$4,995,000	$4,995,000 â–²	New Holding	4,500,000	0.2%	Medical
LRMR Larimar Therapeutics	$4,801,320	$4,801,320 â–²	New Holding	1,066,960	0.2%	Medical
ETON Eton Pharmaceuticals	$4,106,283	$4,106,283 â–²	New Holding	166,381	0.2%	Medical
SAB BIOTHERAPEUTICS INC	$4,021,500	$4,021,500 â–²	New Holding	1,050,000	0.2%	COM NEW
PRCT PROCEPT BioRobotics	$4,001,600	$4,001,600 â–²	New Holding	160,000	0.2%	Medical
GPCR Structure Therapeutics	$3,856,000	$482,000 â–¼	-11.1%	80,000	0.2%	Medical
TECTONIC THERAPEUTIC INC	$3,761,252	$3,761,252 â–²	New Holding	121,684	0.2%	COM
LUNG Pulmonx	$3,596,937	$967,500 â–²	36.8%	2,788,323	0.1%	Medical
IOVA Iovance Biotherapeutics	$3,510,000	$3,510,000 â–²	New Holding	1,000,000	0.1%	Medical
ARGX argenex	$2,555,875	$20,612,037 â–¼	-89.0%	3,500	0.1%	Medical
KARYOPHARM THERAPEUTICS INC	$2,450,800		0.0%	440,000	0.1%	COM NEW
SATELLOS BIOSCIENCE INC	$2,332,841	$2,332,841 â–²	New Holding	414,359	0.1%	COM
ARWR Arrowhead Pharmaceuticals	$1,785,633	$1,785,633 â–²	New Holding	28,479	0.1%	Medical
NSPR InspireMD	$1,704,504	$169,996 â–¼	-9.1%	1,045,708	0.1%	Medical
INSM Insmed	$1,676,080	$6,254,640 â–¼	-78.9%	10,250	0.1%	Medical
CTMX CytomX Therapeutics	$1,410,000	$1,410,000 â–²	New Holding	300,000	0.1%	Medical
CG ONCOLOGY INC	$1,353,600	$10,152,000 â–¼	-88.2%	20,000	0.1%	COM
NEO NeoGenomics	$1,298,500	$1,873,580 â–¼	-59.1%	175,000	0.1%	Medical
QUOIN PHARMACEUTICALS LTD	$480,018	$315,018 â–²	190.9%	72,730	0.0%	SPONSORED ADS
COGT Cogent Biosciences	$384,900	$4,233,900 â–¼	-91.7%	10,000	0.0%	Medical
TYRA Tyra Biosciences	$383,000	$4,404,500 â–¼	-92.0%	10,000	0.0%	Medical
STAA STAAR Surgical	$374,000	$93,500 â–¼	-20.0%	20,000	0.0%	Medical
ANAB AnaptysBio	$332,760	$7,154,340 â–¼	-95.6%	6,000	0.0%	Medical
RAPPORT THERAPEUTICS INC	$312,900	$312,900 â–²	New Holding	10,000	0.0%	COM
RIGEL PHARMACEUTICALS INC	$270,400	$7,842,519 â–¼	-96.7%	10,000	0.0%	COM
ZYMEWORKS INC	$250,400	$2,253,600 â–¼	-90.0%	10,000	0.0%	COM
LB PHARMACEUTICALS INC	$246,600		0.0%	10,000	0.0%	COM SHS
ORUKA THERAPEUTICS INC	$245,250	$9,074,250 â–¼	-97.4%	5,000	0.0%	COM
JASPER THERAPEUTICS INC	$242,105	$66,865 â–²	38.2%	276,312	0.0%	COM NEW
XBI SPDR S&P Biotech ETF	$0	$353,597,000 â–¼	-100.0%	0	0.0%	ETF
FOLD Amicus Therapeutics	$0	$74,151,724 â–¼	-100.0%	0	0.0%	Medical
GSK GSK	$0	$31,336,560 â–¼	-100.0%	0	0.0%	Medical
RAPT THERAPEUTICS INC	$0	$25,876,680 â–¼	-100.0%	0	0.0%	COM NEW
NBIX Neurocrine Biosciences	$0	$24,959,527 â–¼	-100.0%	0	0.0%	Medical
TFX Teleflex	$0	$23,187,600 â–¼	-100.0%	0	0.0%	Medical
CAPR Capricor Therapeutics	$0	$18,654,815 â–¼	-100.0%	0	0.0%	Medical

Showing largest 100 holdings. View all holdings.

More Institutional Buying and Selling Information

SEC Filings and Trading Data

Get 30 Days of MarketBeat All Access for Free

Start Your 30-Day Trial

In-depth profiles and analysis for 20,000 public companies.
Real-time analyst ratings, insider transactions, earnings data, and more.
Our daily ratings and market update email newsletter.

Sign In
Create Account

Your Email Address:

Your Password:

Forgot your password?

Your Email Address:

Choose a Password:

By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Soleus Capital Management, L.P. Top Holdings and 13F Report (2026)

About Soleus Capital Management, L.P.

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools

About MarketBeat

MarketBeat Products

Popular Tools

Financial Calendars

Terms & Info

Soleus Capital Management, L.P. Top Holdings and 13F Report (2026)

About Soleus Capital Management, L.P.

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Map of 500 Largest Holdings ofSoleus Capital Management, L.P.

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools