NASDAQ:CSTL Castle Biosciences (CSTL) Stock Price, News & Analysis $35.19 +0.31 (+0.89%) Closing price 04:00 PM EasternExtended Trading$35.20 +0.01 (+0.03%) As of 04:15 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Castle Biosciences Stock (NASDAQ:CSTL) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Castle Biosciences alerts:Sign Up Key Stats Today's Range$33.90▼$35.8450-Day Range$23.89▼$36.7852-Week Range$17.72▼$44.28Volume439,151 shsAverage Volume397,926 shsMarket Capitalization$1.08 billionP/E RatioN/ADividend YieldN/APrice Target$42.00Consensus RatingModerate Buy Company Overview Castle Biosciences, Inc. is a molecular diagnostics company that develops and commercializes tests designed to help physicians make more informed decisions about cancer diagnosis and treatment. Its products use genomic and molecular information to assess disease characteristics, patient risk and likely outcomes. The company’s portfolio includes DecisionDx-Melanoma, which helps assess the risk of metastasis in patients with cutaneous melanoma; DecisionDx-SCC, which evaluates metastatic risk in certain patients with cutaneous squamous cell carcinoma; and MyPath Melanoma, which assists in distinguishing benign from malignant melanocytic lesions. Castle also offers tests for other cancers, including TissueCypher, which evaluates the risk of progression in patients with Barrett’s esophagus, and DecisionDx-UM for uveal melanoma. Founded in 2008, Castle Biosciences is headquartered in Friendswood, Texas, and primarily serves the U.S. medical and healthcare markets. The company works with dermatologists, oncologists, pathologists and other clinicians by providing test results intended to support personalized patient management. Derek Maetzold serves as president and chief executive officer.AI Generated. May Contain Errors. Read More Castle Biosciences Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks40th Percentile Overall ScoreCSTL MarketRank™: Castle Biosciences scored higher than 40% of companies evaluated by MarketBeat, and ranked 630th out of 901 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.4 / 5Analyst RatingModerate Buy Consensus RatingCastle Biosciences has received a consensus rating of Moderate Buy. The company's average rating score is 2.80, and is based on 1 strong buy rating, 7 buy ratings, 1 hold rating, and 1 sell rating.Upside PotentialCastle Biosciences has a consensus price target of $42.00, representing about 20.2% upside from its current price of $34.93.Amount of Analyst CoverageCastle Biosciences has only been the subject of 2 research reports in the past 90 days.Read more about Castle Biosciences' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Castle Biosciences are expected to grow in the coming year, from ($1.29) to ($0.93) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Castle Biosciences is -52.91, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Castle Biosciences is -52.91, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioCastle Biosciences has a P/B Ratio of 2.17. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.Read more about Castle Biosciences' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted6.89% of the float of Castle Biosciences has been sold short.Short Interest Ratio / Days to CoverCastle Biosciences has a short interest ratio ("days to cover") of 5.05.Change versus previous monthShort interest in Castle Biosciences has recently increased by 12.73%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldCastle Biosciences does not currently pay a dividend.Dividend GrowthCastle Biosciences does not have a long track record of dividend growth. News and Social Media1.8 / 5News Sentiment-0.05 News SentimentCastle Biosciences has a news sentiment score of -0.05. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.49 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 6 news articles for Castle Biosciences this week, compared to 5 articles on an average week.Search InterestOnly 1 people have searched for CSTL on MarketBeat in the last 30 days. This is a decrease of -67% compared to the previous 30 days.MarketBeat Follows3 people have added Castle Biosciences to their MarketBeat watchlist in the last 30 days. Company Ownership1.6 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Castle Biosciences insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $6,083,615.00 in company stock.Percentage Held by Insiders6.10% of the stock of Castle Biosciences is held by insiders.Percentage Held by Institutions92.60% of the stock of Castle Biosciences is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Castle Biosciences' insider trading history. Receive CSTL Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Castle Biosciences and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. CSTL Stock News HeadlinesNew Study Highlights Clinical Need for Molecular Guidance in Atopic Dermatitis Treatment Selection, Reinforcing the Value of AdvanceAD-Tx™51 minutes ago | prnewswire.comCastle Biosciences to Open New Lab in ArizonaSeptember 22 at 5:38 PM | marketscreener.comMCODE RED: AI Meltdown Imminent?After correctly predicting the 2008 and 2020 stock market meltdowns, I believe this AI company is about to trigger the next crash. The research firm Bernstein Research said this AI company has the power to crash the global economy for a decade, the CEO just issued a CODE RED in an internal memo warning employees they're dealing with a critical situation, and another company executive even implied they might need a government bailout. The last time I saw something like this was in 2008 when I predicted a stock market meltdown just three weeks before Lehman went under.September 24 at 1:00 AM | Paradigm Press (Ad)Castle Biosciences to Open New Laboratory Facility in ScottsdaleSeptember 22 at 7:00 AM | prnewswire.comCastle Biosciences (NASDAQ:CSTL) & Acadia Healthcare (NASDAQ:ACHC) Head to Head AnalysisSeptember 20, 2026 | americanbankingnews.comTobin Juvenal Sells 3,306 Shares of Castle Biosciences (NASDAQ:CSTL) StockSeptember 17, 2026 | insidertrades.comCastle Biosciences (NASDAQ:CSTL) Insider Sells 9,050 SharesAugust 28, 2026 | insidertrades.comKristen Oelschlager Sells 12,218 Shares of Castle Biosciences (NASDAQ:CSTL) StockAugust 27, 2026 | insidertrades.comSee More Headlines CSTL Stock Analysis - Frequently Asked Questions How have CSTL shares performed this year? Castle Biosciences' stock was trading at $38.90 at the beginning of 2026. Since then, CSTL shares have decreased by 10.2% and is now trading at $34.93. How were Castle Biosciences' earnings last quarter? Castle Biosciences, Inc. (NASDAQ:CSTL) issued its quarterly earnings data on Thursday, July, 30th. The company reported ($0.07) EPS for the quarter, beating the consensus estimate of ($0.41) by $0.34. The company had revenue of $99.86 million for the quarter, compared to analysts' expectations of $86.23 million. Castle Biosciences had a negative trailing twelve-month return on equity of 4.15% and a negative net margin of 5.43%. Read the conference call transcript. When did Castle Biosciences IPO? Castle Biosciences (CSTL) raised $60 million in an initial public offering on Wednesday, July 24th 2019. The company issued 4,000,000 shares at $14.00-$16.00 per share. SVB Leerink and Baird acted as the underwriters for the IPO and Canaccord Genuity and BTIG were co-managers. Who are Castle Biosciences' major shareholders? Top institutional shareholders of Castle Biosciences include BlackRock Inc. (10.78%), Jefferies Financial Group Inc. (2.12%), AIGH Capital Management LLC (1.78%) and Connor Clark & Lunn Investment Management Ltd. (1.09%). Insiders that own company stock include Kristen M Oelschlager, Frank Stokes, Tobin W Juvenal, Derek J Maetzold, G Bradley Cole and Daniel Bradbury. View institutional ownership trends. How do I buy shares of Castle Biosciences? Shares of CSTL stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Castle Biosciences own? Based on aggregate information from My MarketBeat watchlists, some other companies that Castle Biosciences investors own include NVIDIA (NVDA), Meta Platforms (META), CrowdStrike (CRWD), PayPal (PYPL), Adobe (ADBE), Advanced Micro Devices (AMD) and Broadcom (AVGO). Company Calendar Last Earnings7/30/2026Today9/24/2026Next Earnings (Estimated)11/02/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (1m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 CSTL's financial health is in the Green zone, according to TradeSmith. CSTL has been in this zone for over one month. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Healthcare Providers & Services Sub-IndustryHealthcare Services Current SymbolNASDAQ:CSTL CIK1447362 Webcastlebiosciences.com Phone(866) 788-9007FaxN/AEmployees1,002Year Founded2008Price Target and Rating Average Price Target for Castle Biosciences$42.00 High Price Target$52.00 Low Price Target$35.00 Potential Upside/Downside+19.4%Consensus RatingModerate Buy Rating Score (0-4)2.80 Research Coverage10 Analysts Profitability EPS (Trailing Twelve Months)($0.66) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$24.16 million Net Margins-5.43% Pretax Margin-5.37% Return on Equity-4.15% Return on Assets-3.45% Debt Debt-to-Equity Ratio0.02 Current Ratio6.04 Quick Ratio5.85 Sales & Book Value Annual Sales$357.28 million Price / Sales3.01 Cash Flow$1.12 per share Price / Cash Flow31.31 Book Value$16.13 per share Price / Book2.18Miscellaneous Outstanding Shares30,550,000Free Float28,686,000Market Cap$1.08 billion OptionableOptionable Beta0.99 Social Links 7 Energy Stocks to Buy and Hold ForeverWith the proliferation of data centers and electric vehicles, the electric grid will only get more strained. Download this report to learn how energy stocks can play a role in your portfolio as the global demand for energy continues to grow.Get This Free Report This page (NASDAQ:CSTL) was last updated on 9/24/2026 by MarketBeat.com Staff. From Our PartnersA letter from Shannon StansberryPorter Stansberry nearly canceled the entire project. 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