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Castle Biosciences (CSTL) Competitors

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$24.68 -0.80 (-3.14%)
Closing price 07/24/2026 04:00 PM Eastern
Extended Trading
$24.74 +0.05 (+0.22%)
As of 07/24/2026 07:34 PM Eastern
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CSTL vs. PGNY, HTFL, AGL, AVAH, and ADUS

Should you buy Castle Biosciences stock or one of its competitors? MarketBeat compares Castle Biosciences with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Castle Biosciences include Progyny (PGNY), Heartflow (HTFL), Agilon Health (AGL), Aveanna Healthcare (AVAH), and Addus HomeCare (ADUS). These companies are all part of the "healthcare" industry.

How does Castle Biosciences compare to Progyny?

Progyny (NASDAQ:PGNY) and Castle Biosciences (NASDAQ:CSTL) are both medical companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, profitability, risk, institutional ownership, earnings, analyst recommendations, valuation and dividends.

Progyny has a beta of 1.01, meaning that its stock price is 1% more volatile than the broader market. Comparatively, Castle Biosciences has a beta of 1, meaning that its stock price has a similar volatility profile to the broader market.

Progyny has higher revenue and earnings than Castle Biosciences. Castle Biosciences is trading at a lower price-to-earnings ratio than Progyny, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Progyny$1.29B1.89$58.52M$0.7740.51
Castle Biosciences$339.92M2.20-$24.16M-$0.44N/A

94.9% of Progyny shares are held by institutional investors. Comparatively, 92.6% of Castle Biosciences shares are held by institutional investors. 9.9% of Progyny shares are held by company insiders. Comparatively, 6.1% of Castle Biosciences shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

In the previous week, Progyny had 7 more articles in the media than Castle Biosciences. MarketBeat recorded 10 mentions for Progyny and 3 mentions for Castle Biosciences. Progyny's average media sentiment score of 1.07 beat Castle Biosciences' score of 0.62 indicating that Progyny is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Progyny
2 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive
Castle Biosciences
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Progyny currently has a consensus price target of $32.67, indicating a potential upside of 4.73%. Castle Biosciences has a consensus price target of $42.43, indicating a potential upside of 71.91%. Given Castle Biosciences' higher possible upside, analysts plainly believe Castle Biosciences is more favorable than Progyny.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Progyny
0 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.92
Castle Biosciences
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80

Progyny has a net margin of 5.23% compared to Castle Biosciences' net margin of -3.78%. Progyny's return on equity of 13.34% beat Castle Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Progyny5.23% 13.34% 9.03%
Castle Biosciences -3.78%-2.77%-2.30%

Summary

Progyny beats Castle Biosciences on 14 of the 16 factors compared between the two stocks.

How does Castle Biosciences compare to Heartflow?

Castle Biosciences (NASDAQ:CSTL) and Heartflow (NASDAQ:HTFL) are both medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their analyst recommendations, profitability, risk, institutional ownership, valuation, dividends, media sentiment and earnings.

Castle Biosciences has a net margin of -3.78% compared to Heartflow's net margin of -58.42%. Heartflow's return on equity of 0.00% beat Castle Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Castle Biosciences-3.78% -2.77% -2.30%
Heartflow -58.42%N/A -20.02%

Castle Biosciences has higher revenue and earnings than Heartflow. Castle Biosciences is trading at a lower price-to-earnings ratio than Heartflow, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Castle Biosciences$339.92M2.20-$24.16M-$0.44N/A
Heartflow$191.42M10.87-$116.79M-$3.11N/A

Castle Biosciences currently has a consensus price target of $42.43, suggesting a potential upside of 71.91%. Heartflow has a consensus price target of $37.00, suggesting a potential upside of 53.40%. Given Castle Biosciences' stronger consensus rating and higher probable upside, equities research analysts plainly believe Castle Biosciences is more favorable than Heartflow.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Castle Biosciences
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80
Heartflow
1 Sell rating(s)
2 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.70

92.6% of Castle Biosciences shares are held by institutional investors. 6.1% of Castle Biosciences shares are held by insiders. Comparatively, 7.7% of Heartflow shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

In the previous week, Castle Biosciences and Castle Biosciences both had 3 articles in the media. Heartflow's average media sentiment score of 1.61 beat Castle Biosciences' score of 0.62 indicating that Heartflow is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Castle Biosciences
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Heartflow
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Summary

Castle Biosciences beats Heartflow on 9 of the 14 factors compared between the two stocks.

How does Castle Biosciences compare to Agilon Health?

Castle Biosciences (NASDAQ:CSTL) and Agilon Health (NYSE:AGL) are both small-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their valuation, media sentiment, analyst recommendations, institutional ownership, risk, dividends, earnings and profitability.

Castle Biosciences has a net margin of -3.78% compared to Agilon Health's net margin of -6.09%. Castle Biosciences' return on equity of -2.77% beat Agilon Health's return on equity.

Company Net Margins Return on Equity Return on Assets
Castle Biosciences-3.78% -2.77% -2.30%
Agilon Health -6.09%-146.03%-24.55%

Castle Biosciences has higher earnings, but lower revenue than Agilon Health. Castle Biosciences is trading at a lower price-to-earnings ratio than Agilon Health, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Castle Biosciences$339.92M2.20-$24.16M-$0.44N/A
Agilon Health$5.82B0.28-$391.35M-$21.56N/A

Castle Biosciences has a beta of 1, meaning that its stock price has a similar volatility profile to the broader market.Comparatively, Agilon Health has a beta of 2.98, meaning that its stock price is 198% more volatile than the broader market.

Castle Biosciences presently has a consensus price target of $42.43, suggesting a potential upside of 71.91%. Agilon Health has a consensus price target of $66.50, suggesting a potential downside of 32.03%. Given Castle Biosciences' stronger consensus rating and higher probable upside, equities analysts plainly believe Castle Biosciences is more favorable than Agilon Health.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Castle Biosciences
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80
Agilon Health
3 Sell rating(s)
6 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.14

92.6% of Castle Biosciences shares are owned by institutional investors. 6.1% of Castle Biosciences shares are owned by company insiders. Comparatively, 2.5% of Agilon Health shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

In the previous week, Agilon Health had 3 more articles in the media than Castle Biosciences. MarketBeat recorded 6 mentions for Agilon Health and 3 mentions for Castle Biosciences. Castle Biosciences' average media sentiment score of 0.62 beat Agilon Health's score of 0.25 indicating that Castle Biosciences is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Castle Biosciences
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Agilon Health
1 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Castle Biosciences beats Agilon Health on 13 of the 17 factors compared between the two stocks.

How does Castle Biosciences compare to Aveanna Healthcare?

Castle Biosciences (NASDAQ:CSTL) and Aveanna Healthcare (NASDAQ:AVAH) are both medical companies, but which is the better investment? We will contrast the two companies based on the strength of their media sentiment, profitability, valuation, institutional ownership, analyst recommendations, earnings, risk and dividends.

Aveanna Healthcare has higher revenue and earnings than Castle Biosciences. Castle Biosciences is trading at a lower price-to-earnings ratio than Aveanna Healthcare, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Castle Biosciences$339.92M2.20-$24.16M-$0.44N/A
Aveanna Healthcare$2.52B0.82$225.03M$1.188.01

Aveanna Healthcare has a net margin of 10.37% compared to Castle Biosciences' net margin of -3.78%. Aveanna Healthcare's return on equity of 124.68% beat Castle Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Castle Biosciences-3.78% -2.77% -2.30%
Aveanna Healthcare 10.37%124.68%7.07%

Castle Biosciences has a beta of 1, indicating that its share price has a similar volatility profile to the broader market.Comparatively, Aveanna Healthcare has a beta of 1.89, indicating that its share price is 89% more volatile than the broader market.

Castle Biosciences currently has a consensus price target of $42.43, suggesting a potential upside of 71.91%. Aveanna Healthcare has a consensus price target of $10.78, suggesting a potential upside of 14.05%. Given Castle Biosciences' stronger consensus rating and higher possible upside, research analysts clearly believe Castle Biosciences is more favorable than Aveanna Healthcare.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Castle Biosciences
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80
Aveanna Healthcare
0 Sell rating(s)
5 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.67

92.6% of Castle Biosciences shares are owned by institutional investors. Comparatively, 88.0% of Aveanna Healthcare shares are owned by institutional investors. 6.1% of Castle Biosciences shares are owned by insiders. Comparatively, 5.3% of Aveanna Healthcare shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

In the previous week, Aveanna Healthcare had 2 more articles in the media than Castle Biosciences. MarketBeat recorded 5 mentions for Aveanna Healthcare and 3 mentions for Castle Biosciences. Aveanna Healthcare's average media sentiment score of 1.03 beat Castle Biosciences' score of 0.62 indicating that Aveanna Healthcare is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Castle Biosciences
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Aveanna Healthcare
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Aveanna Healthcare beats Castle Biosciences on 10 of the 16 factors compared between the two stocks.

How does Castle Biosciences compare to Addus HomeCare?

Castle Biosciences (NASDAQ:CSTL) and Addus HomeCare (NASDAQ:ADUS) are both medical companies, but which is the superior business? We will compare the two companies based on the strength of their analyst recommendations, valuation, dividends, media sentiment, institutional ownership, profitability, earnings and risk.

92.6% of Castle Biosciences shares are owned by institutional investors. Comparatively, 95.4% of Addus HomeCare shares are owned by institutional investors. 6.1% of Castle Biosciences shares are owned by company insiders. Comparatively, 4.1% of Addus HomeCare shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Addus HomeCare has a net margin of 6.89% compared to Castle Biosciences' net margin of -3.78%. Addus HomeCare's return on equity of 9.80% beat Castle Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Castle Biosciences-3.78% -2.77% -2.30%
Addus HomeCare 6.89%9.80%7.34%

Castle Biosciences presently has a consensus price target of $42.43, suggesting a potential upside of 71.91%. Addus HomeCare has a consensus price target of $131.50, suggesting a potential upside of 14.80%. Given Castle Biosciences' stronger consensus rating and higher possible upside, equities research analysts clearly believe Castle Biosciences is more favorable than Addus HomeCare.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Castle Biosciences
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80
Addus HomeCare
1 Sell rating(s)
2 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.73

In the previous week, Addus HomeCare had 2 more articles in the media than Castle Biosciences. MarketBeat recorded 5 mentions for Addus HomeCare and 3 mentions for Castle Biosciences. Addus HomeCare's average media sentiment score of 1.00 beat Castle Biosciences' score of 0.62 indicating that Addus HomeCare is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Castle Biosciences
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Addus HomeCare
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Castle Biosciences has a beta of 1, meaning that its share price has a similar volatility profile to the broader market.Comparatively, Addus HomeCare has a beta of 0.88, meaning that its share price is 12% less volatile than the broader market.

Addus HomeCare has higher revenue and earnings than Castle Biosciences. Castle Biosciences is trading at a lower price-to-earnings ratio than Addus HomeCare, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Castle Biosciences$339.92M2.20-$24.16M-$0.44N/A
Addus HomeCare$1.42B1.50$95.91M$5.4121.17

Summary

Addus HomeCare beats Castle Biosciences on 10 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding CSTL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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CSTL vs. The Competition

MetricCastle BiosciencesMED IndustryMedical SectorNASDAQ Exchange
Market Cap$772.81M$3.67B$6.87B$12.26B
Dividend YieldN/A2.19%2.67%9.79%
P/E Ratio-56.0921.4827.1423.64
Price / Sales2.20170.08517.0889.50
Price / Cash22.89157.9050.5459.64
Price / Book1.537.8810.286.07
Net Income-$24.16M$23.86M$3.60B$331.99M
7 Day Performance2.15%-3.82%-1.27%-0.63%
1 Month Performance7.73%-2.61%-0.37%-2.00%
1 Year Performance53.58%32.79%18.30%13.62%

Castle Biosciences Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
CSTL
Castle Biosciences
3.6299 of 5 stars
$24.68
-3.1%
$42.43
+71.9%
+50.2%$772.81M$339.92MN/A540
PGNY
Progyny
3.3488 of 5 stars
$32.32
+1.1%
$30.73
-4.9%
+35.6%$2.53B$1.29B41.97310
HTFL
Heartflow
3.1354 of 5 stars
$25.56
-2.3%
$37.00
+44.8%
N/A$2.20B$176.03MN/A699
AGL
Agilon Health
0.9118 of 5 stars
$124.49
+7.5%
$64.00
-48.6%
+88.6%$2.08B$5.93BN/A1,076
AVAH
Aveanna Healthcare
4.6311 of 5 stars
$9.32
-3.6%
$10.78
+15.6%
+139.8%$2.03B$2.43B7.8935,500

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This page (NASDAQ:CSTL) was last updated on 7/25/2026 by MarketBeat.com Staff.
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