Iovance Biotherapeutics (IOVA) Financials

$3.70 +0.08 (+2.21%)

Closing price 05/11/2026 04:00 PM Eastern

Extended Trading

$3.76 +0.06 (+1.62%)

As of 04:06 AM Eastern

Annual Income Statements for Iovance Biotherapeutics

This table shows Iovance Biotherapeutics' income and expenses over time, based on annual financial data. All values are USD millions unless otherwise specified.

Metric	2015	2016	2017	2018	2019	2020	2021	2022	2023	2024	2025
Period end date	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025
Net Income / (Loss) Attributable to Common Shareholders	-28	-102	-92	-124	-198	-260	-342	-396	-444	-372	-391
Consolidated Net Income / (Loss)	-28	-53	-92	-124	-198	-260	-342	-396	-444	-372	-391
Net Income / (Loss) Continuing Operations	-28	-53	-92	-124	-198	-260	-342	-396	-444	-372	-391
Total Pre-Tax Income	-28	-53	-92	-124	-198	-260	-342	-396	-448	-375	-393
Total Operating Income	-28	-54	-93	-128	-207	-262	-343	-399	-461	-395	-403
Total Gross Profit	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.16	71	90
Total Revenue	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	1.19	164	264
Operating Revenue	0.00	0.00	-	-	-	-	0.00	0.00	1.19	164	264
Total Cost of Revenue	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	1.03	93	173
Operating Cost of Revenue	-	-	-	-	-	-	0.00	0.00	1.03	93	173
Total Operating Expenses	28	54	93	128	207	262	343	399	461	466	494
Selling, General & Admin Expense	12	27	21	28	41	60	84	104	106	152	152
Research & Development Expense	15	27	72	100	166	202	259	295	333	276	300
Depreciation Expense	-	-	-	-	-	-	-	-	21	38	36
Restructuring Charge	-	-	-	-	-	-	-	-	0.00	0.00	5.14
Total Other Income / (Expense), net	0.20	0.75	0.81	4.68	9.32	2.36	0.45	2.99	13	20	10
Interest & Investment Income	0.20	0.75	0.81	4.68	9.32	2.36	0.45	2.99	13	20	10
Income Tax Expense	-	-	-	-	-	-	0.00	0.00	-3.48	-2.83	-2.07
Basic Earnings per Share	($0.62)	($1.85)	($1.41)	($1.27)	($1.59)	($1.88)	($2.23)	($2.49)	($1.89)	($1.28)	($1.09)
Weighted Average Basic Shares Outstanding	44.41M	55.27M	65.24M	97.28M	124.34M	138.30M	153.41M	159.26M	235.13M	289.88M	357.35M
Diluted Earnings per Share	($0.62)	($1.85)	($1.41)	($1.27)	($1.59)	($1.88)	($2.23)	($2.49)	($1.89)	($1.28)	($1.09)
Weighted Average Diluted Shares Outstanding	44.41M	55.27M	65.24M	97.28M	124.34M	138.30M	153.41M	159.26M	235.13M	289.88M	357.35M
Weighted Average Basic & Diluted Shares Outstanding	44.41M	55.27M	65.24M	97.28M	124.34M	138.30M	157.17M	224.24M	279.31M	327.88M	411.96M

This table shows Iovance Biotherapeutics' income and expenses over time, based on quarterly financial data. All values are USD millions unless otherwise specified.

Metric	Q3 2023	Q4 2023	Q1 2024	Q2 2024	Q3 2024	Q4 2024	Q1 2025	Q2 2025	Q3 2025	Q4 2025	Q1 2026
Period end date	9/30/2023	12/31/2023	3/31/2024	6/30/2024	9/30/2024	12/31/2024	3/31/2025	6/30/2025	9/30/2025	12/31/2025	3/31/2026
Net Income / (Loss) Attributable to Common Shareholders	-114	-116	-113	-97	-84	-79	-116	-112	-91	-72	-79
Consolidated Net Income / (Loss)	-114	-116	-113	-97	-84	-79	-116	-112	-91	-72	-79
Net Income / (Loss) Continuing Operations	-114	-116	-113	-97	-84	-79	-116	-112	-91	-72	-79
Total Pre-Tax Income	-115	-118	-114	-99	-85	-77	-118	-110	-94	-72	-80
Total Operating Income	-118	-121	-118	-102	-89	-87	-121	-114	-95	-73	-81
Total Gross Profit	-3.87	-3.88	-6.55	-0.26	27	28	6.61	3.29	29	58	29
Total Revenue	0.47	0.48	0.72	31	59	74	49	60	67	87	71
Operating Revenue	0.47	0.48	0.72	31	59	74	49	60	67	87	71
Total Cost of Revenue	4.34	4.37	7.26	31	32	46	43	57	38	28	42
Operating Cost of Revenue	4.34	4.37	7.26	31	32	46	43	57	38	28	42
Total Operating Expenses	114	117	111	102	116	115	128	117	124	132	110
Selling, General & Admin Expense	27	30	31	40	39	43	44	38	35	36	39
Research & Development Expense	88	87	80	62	67	72	76	79	75	69	62
Depreciation Expense	-	-	-	-	9.73	-	8.07	-	9.01	-	8.54
Total Other Income / (Expense), net	3.36	3.12	3.34	3.36	4.01	9.58	3.22	4.10	1.24	1.74	1.33
Interest & Investment Income	3.36	3.12	3.34	3.36	4.01	9.58	3.22	4.10	1.24	1.74	1.33
Income Tax Expense	-1.24	-1.76	-1.41	-1.46	-1.52	1.56	-1.84	1.99	-2.41	0.18	-0.67
Basic Earnings per Share	($0.46)	($0.46)	($0.42)	($0.34)	($0.28)	($0.24)	($0.36)	($0.33)	($0.25)	($0.15)	($0.19)
Weighted Average Basic Shares Outstanding	245.82M	235.13M	266.22M	284.82M	303.27M	289.88M	322.87M	334.51M	364.04M	357.35M	418.51M
Diluted Earnings per Share	($0.46)	($0.46)	($0.42)	($0.34)	-	($0.24)	($0.36)	($0.33)	-	-	($0.19)
Weighted Average Diluted Shares Outstanding	245.82M	235.13M	266.22M	284.82M	304.78M	289.88M	322.87M	334.51M	396.97M	357.35M	418.51M
Weighted Average Basic & Diluted Shares Outstanding	255.92M	279.31M	279.83M	303.51M	304.78M	327.88M	333.93M	361.85M	396.97M	411.96M	446.50M

This table details how cash moves in and out of Iovance Biotherapeutics' business through operations, investing, and financing, using annual figures. All values are USD millions unless otherwise specified.

Metric	2015	2016	2017	2018	2019	2020	2021	2022	2023	2024	2025
Period end date	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025
Net Change in Cash & Equivalents	-11	73	39	-63	-63	53	11	154	-57	-59	47
Net Cash From Operating Activities	-18	-33	-79	-101	-159	-205	-228	-293	-362	-353	-302
Net Cash From Continuing Operating Activities	-18	-33	-79	-101	-159	-205	-227	-293	-362	-353	-302
Net Income / (Loss) Continuing Operations	-28	-53	-92	-124	-198	-260	-342	-396	-444	-372	-391
Consolidated Net Income / (Loss)	-28	-53	-92	-124	-198	-260	-342	-396	-444	-372	-391
Depreciation Expense	1.00	0.98	0.95	0.96	1.17	1.14	3.11	9.31	12	11	13
Amortization Expense	0.00	-0.07	0.02	-1.33	3.53	9.44	17	12	18	27	27
Non-Cash Adjustments To Reconcile Net Income	8.52	19	12	20	18	29	70	84	63	99	75
Changes in Operating Assets and Liabilities, net	-0.24	0.42	0.42	2.67	16	14	25	-2.89	-10	-118	-26
Net Cash From Investing Activities	-71	8.89	59	-386	90	-318	0.13	256	-155	-96	47
Net Cash From Continuing Investing Activities	-71	8.89	59	-386	90	-318	0.13	256	-155	-96	47
Purchase of Property, Plant & Equipment	-1.14	-1.52	-1.03	-1.20	-6.92	-47	-38	-20	-22	-11	-34
Acquisitions	-	-	-	-	-	-	0.00	0.00	-213	-53	0.00
Purchase of Investments	-141	-110	-	-426	-418	-948	-725	-246	-206	-461	-319
Sale and/or Maturity of Investments	71	121	60	41	515	677	763	523	286	428	400
Net Cash From Financing Activities	78	97	59	424	6.13	576	239	190	463	391	301
Net Cash From Continuing Financing Activities	78	97	59	424	6.13	576	239	190	463	391	301
Issuance of Common Equity	68	96	-	399	0.00	567	205	191	466	400	308
Other Financing Activities, net	9.96	1.22	59	26	6.13	9.38	34	-1.01	-2.73	-9.59	-7.04
Effect of Exchange Rate Changes	-	-	-	-	-	-	0.00	0.00	-2.74	-0.54	1.14

This table details how cash moves in and out of Iovance Biotherapeutics' business through operations, investing, and financing, using quarterly figures. All values are USD millions unless otherwise specified.

Metric	Q3 2023	Q4 2023	Q1 2024	Q2 2024	Q3 2024	Q4 2024	Q1 2025	Q2 2025	Q3 2025	Q4 2025	Q1 2026
Period end date	9/30/2023	12/31/2023	3/31/2024	6/30/2024	9/30/2024	12/31/2024	3/31/2025	6/30/2025	9/30/2025	12/31/2025	3/31/2026
Net Change in Cash & Equivalents	38	-153	-41	94	-65	-48	56	-40	26	4.96	33
Net Cash From Operating Activities	-84	-84	-122	-98	-59	-73	-104	-67	-79	-53	-72
Net Cash From Continuing Operating Activities	-83	-84	-122	-98	-59	-73	-104	-67	-79	-53	-72
Net Income / (Loss) Continuing Operations	-114	-116	-113	-97	-84	-79	-116	-112	-91	-72	-79
Consolidated Net Income / (Loss)	-114	-116	-113	-97	-84	-79	-116	-112	-91	-72	-79
Depreciation Expense	2.92	2.95	2.98	2.99	3.03	2.98	2.57	3.36	2.99	3.72	2.82
Amortization Expense	5.93	5.04	4.59	5.38	5.46	5.94	6.22	6.57	6.98	7.58	6.47
Non-Cash Adjustments To Reconcile Net Income	9.48	12	14	33	31	21	23	21	19	15	9.20
Changes in Operating Assets and Liabilities, net	12	13	-31	-43	-15	-24	-19	14	-17	-7.11	-12
Net Cash From Investing Activities	-79	-73	-112	40	-49	24	16	14	17	0.78	11
Net Cash From Continuing Investing Activities	-79	-73	-112	40	-49	24	16	14	17	0.78	11
Purchase of Property, Plant & Equipment	-3.58	-3.53	-4.17	-0.44	-2.29	-4.17	-6.21	-7.46	-11	-9.32	-6.61
Purchase of Investments	-93	-108	-142	-74	-157	-88	-98	-69	-92	-60	-56
Sale and/or Maturity of Investments	21	38	87	115	110	116	120	90	120	70	74
Net Cash From Financing Activities	203	0.96	194	153	42	2.31	143	13	88	56	94
Net Cash From Continuing Financing Activities	203	0.96	194	153	42	2.31	143	13	88	56	94
Issuance of Common Equity	203	1.14	198	153	48	1.39	149	14	89	57	99
Other Financing Activities, net	-0.38	-0.18	-4.34	-0.61	-5.56	0.92	-5.63	-0.50	-0.47	-0.45	-4.18
Effect of Exchange Rate Changes	-1.99	3.02	-0.49	-0.13	1.25	-1.18	0.51	0.74	-0.68	0.58	-0.21

This table presents Iovance Biotherapeutics' assets and liabilities at the end of each period, using annual balance sheet data. All values are USD millions unless otherwise specified.

Metric	2015	2016	2017	2018	2019	2020	2021	2022	2023	2024	2025
Period end date	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025
Total Assets	106	172	155	481	345	768	777	664	780	910	913
Total Current Assets	104	170	149	475	316	636	508	479	308	457	443
Cash & Equivalents	34	107	145	82	14	67	78	232	115	116	163
Short-Term Investments	70	60	0.00	386	293	562	426	240	165	208	134
Accounts Receivable	-	-	-	-	-	-	-	0.00	0.15	69	82
Inventories, net	-	-	-	-	-	-	-	0.00	10	52	52
Prepaid Expenses	0.28	3.04	3.92	6.85	9.41	6.66	3.55	7.27	17	12	12
Plant, Property, & Equipment, net	1.68	2.37	2.45	2.68	8.54	59	101	105	114	109	131
Total Noncurrent Assets	0.00	0.00	3.63	2.76	20	73	71	73	358	344	339
Intangible Assets	-	-	-	-	-	-	-	0.00	229	282	279
Other Noncurrent Operating Assets	-	0.00	3.63	2.76	20	73	71	73	129	62	60
Total Liabilities & Shareholders' Equity	106	172	155	481	345	768	777	664	780	910	913
Total Liabilities	1.63	4.97	9.89	15	46	112	156	164	196	200	215
Total Current Liabilities	1.63	4.97	9.60	14	39	55	89	91	110	122	138
Short-Term Debt	-	-	-	-	-	-	-	-	-	0.00	1.00
Accounts Payable	0.96	0.86	1.23	2.74	16	14	27	27	33	28	22
Accrued Expenses	0.67	4.11	8.36	12	16	35	57	52	69	82	111
Other Current Liabilities	-	-	-	-	7.25	6.28	5.06	13	7.78	13	4.04
Total Noncurrent Liabilities	0.00	0.00	0.30	0.23	6.60	57	66	73	85	78	76
Noncurrent Deferred & Payable Income Tax Liabilities	-	-	-	-	-	-	-	0.00	17	32	32
Other Noncurrent Operating Liabilities	-	-	-	0.23	6.60	57	65	72	67	44	44
Commitments & Contingencies	0.00	0.00	0.00	-	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Total Equity & Noncontrolling Interests	104	167	145	466	299	656	622	500	585	710	699
Total Preferred & Common Equity	104	167	145	466	299	656	622	500	585	710	699
Preferred Stock	-	-	-	0.01	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Total Common Equity	104	167	145	466	299	656	622	500	585	710	699
Common Stock	208	324	395	839	869	1,487	1,795	2,069	2,594	3,096	3,458
Retained Earnings	-104	-157	-249	-373	-571	-830	-1,172	-1,568	-2,012	-2,385	-2,776
Accumulated Other Comprehensive Income / (Loss)	0.05	0.03	0.00	-0.04	0.22	0.02	-0.60	-0.90	2.53	-1.05	16

This table presents Iovance Biotherapeutics' assets and liabilities at the end of each period, using quarterly balance sheet data. All values are USD millions unless otherwise specified.

Metric	Q3 2022	Q1 2023	Q2 2023	Q3 2023	Q1 2024	Q2 2024	Q3 2024	Q1 2025	Q2 2025	Q3 2025	Q1 2026
Period end date	9/30/2022	3/31/2023	6/30/2023	9/30/2023	3/31/2024	6/30/2024	9/30/2024	3/31/2025	6/30/2025	9/30/2025	3/31/2026
Total Assets	546	825	757	852	870	964	991	967	907	905	926
Total Current Assets	370	638	275	383	386	482	499	513	423	429	467
Cash & Equivalents	118	543	230	268	134	229	164	172	132	158	197
Short-Term Investments	242	83	21	94	222	184	233	188	169	143	117
Accounts Receivable	-	-	0.03	-	0.23	32	56	71	60	67	82
Inventories, net	-	-	9.72	9.20	18	28	39	66	50	52	58
Prepaid Expenses	9.71	11	14	12	11	10	6.74	16	12	9.82	13
Plant, Property, & Equipment, net	101	110	113	113	112	111	113	112	122	127	131
Total Noncurrent Assets	69	71	303	357	366	371	380	343	362	349	328
Intangible Assets	-	-	236	224	294	295	307	285	296	285	269
Other Noncurrent Operating Assets	69	71	68	133	72	76	73	57	66	64	59
Total Liabilities & Shareholders' Equity	546	825	757	852	870	964	991	967	907	905	926
Total Liabilities	152	158	179	178	190	196	218	199	209	203	204
Total Current Liabilities	79	87	89	91	83	94	118	123	129	126	129
Short-Term Debt	-	-	-	-	-	-	-	1.00	1.00	1.00	1.00
Accounts Payable	24	32	31	19	26	20	32	28	32	31	37
Accrued Expenses	48	43	47	61	46	62	75	85	89	87	88
Other Current Liabilities	7.17	13	11	10	11	11	12	8.50	7.07	6.28	2.90
Total Noncurrent Liabilities	73	71	90	87	107	102	100	76	80	77	74
Noncurrent Deferred & Payable Income Tax Liabilities	-	-	20	18	33	32	32	32	35	32	31
Other Noncurrent Operating Liabilities	72	70	69	68	72	69	66	44	45	45	44
Commitments & Contingencies	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Total Equity & Noncontrolling Interests	394	667	579	674	680	769	773	768	698	702	722
Total Preferred & Common Equity	394	667	579	674	680	769	773	768	698	702	722
Preferred Stock	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Total Common Equity	394	667	579	674	680	769	773	768	698	702	722
Common Stock	1,859	2,343	2,360	2,579	2,805	2,990	3,063	3,262	3,290	3,390	3,564
Retained Earnings	-1,463	-1,676	-1,782	-1,896	-2,125	-2,222	-2,306	-2,501	-2,612	-2,704	-2,855
Accumulated Other Comprehensive Income / (Loss)	-2.04	-0.13	0.33	-9.10	0.12	0.53	16	6.29	21	16	13

This table displays calculated financial ratios and metrics derived from Iovance Biotherapeutics' official financial filings.

Metric	2015	2016	2017	2018	2019	2020	2021	2022	2023	2024	2025
Period end date	12/31/2015	12/31/2016	12/31/2017	12/31/2018	12/31/2019	12/31/2020	12/31/2021	12/31/2022	12/31/2023	12/31/2024	12/31/2025
Growth Metrics	-	-	-	-	-	-	-	-	-	-	-
Revenue Growth	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	13,698.99%	60.60%
EBITDA Growth	-124.72%	-96.33%	-74.28%	-39.96%	-57.17%	-24.33%	-28.39%	-16.91%	-14.25%	16.03%	-1.61%
EBIT Growth	-131.38%	-92.53%	-73.15%	-38.09%	-61.29%	-26.62%	-30.83%	-16.39%	-15.46%	14.17%	-2.04%
NOPAT Growth	-131.38%	-92.53%	-73.15%	-38.09%	-61.29%	-26.62%	-30.83%	-16.39%	-15.46%	14.17%	-2.04%
Net Income Growth	-129.83%	-91.23%	-74.05%	-34.23%	-59.86%	-31.40%	-31.85%	-15.67%	-12.16%	16.18%	-5.05%
EPS Growth	-29.17%	-198.39%	23.78%	9.93%	-25.20%	-18.24%	-18.62%	-11.66%	24.10%	32.28%	14.84%
Operating Cash Flow Growth	-112.92%	-77.73%	-140.94%	-28.64%	-56.93%	-29.11%	-11.12%	-28.44%	-23.59%	2.44%	14.33%
Free Cash Flow Firm Growth	-90.63%	-89.41%	-71.67%	-35.05%	-59.18%	-57.18%	-6.81%	-20.39%	-115.58%	40.81%	17.08%
Invested Capital Growth	604.69%	38.70%	-75.89%	-2,257.41%	-248.07%	433.67%	-23.96%	8.68%	1,267.20%	26.78%	3.86%
Revenue Q/Q Growth	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	68.18%	80.58%	5.22%
EBITDA Q/Q Growth	-14.33%	-16.50%	-12.47%	-8.25%	-12.59%	18.77%	-41.10%	-2.12%	-2.69%	8.96%	3.84%
EBIT Q/Q Growth	-14.89%	-16.11%	-12.27%	-7.43%	-17.07%	17.49%	-35.56%	-1.93%	-3.19%	8.07%	3.15%
NOPAT Q/Q Growth	-14.89%	-16.11%	-12.27%	-7.43%	-17.07%	17.49%	-35.56%	-1.93%	-3.19%	8.07%	3.15%
Net Income Q/Q Growth	-14.45%	-16.08%	-12.41%	-5.75%	-18.61%	-1.90%	-9.94%	-1.54%	-2.55%	9.22%	1.67%
EPS Q/Q Growth	-21.57%	-8.82%	-2.17%	7.30%	-18.66%	2.59%	-8.78%	-0.40%	9.13%	14.67%	0.00%
Operating Cash Flow Q/Q Growth	-21.60%	-20.60%	-12.60%	-11.68%	-16.30%	-4.52%	3.73%	-8.86%	-1.77%	2.94%	6.42%
Free Cash Flow Firm Q/Q Growth	46.70%	-203.80%	-7.57%	-15.43%	-13.29%	3.62%	-4.24%	-9.16%	-1.31%	1.57%	6.22%
Invested Capital Q/Q Growth	-98.37%	396.69%	-94.76%	60.10%	-19.07%	1,273.00%	-53.90%	-20.51%	-2.52%	2.83%	0.03%
Profitability Metrics	-	-	-	-	-	-	-	-	-	-	-
Gross Margin	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-804.54%	24.43%	34.28%
EBITDA Margin	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-36,252.06%	-220.60%	-137.85%
Operating Margin	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-38,734.99%	-240.92%	-153.08%
EBIT Margin	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-38,734.99%	-240.92%	-153.08%
Profit (Net Income) Margin	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-37,345.42%	-226.84%	-148.38%
Tax Burden Percent	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	99.22%	99.25%	99.47%
Interest Burden Percent	99.28%	98.61%	99.12%	96.35%	95.50%	99.10%	99.87%	99.25%	97.17%	94.87%	97.44%
Effective Tax Rate	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Return on Invested Capital (ROIC)	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-196.51%	-79.81%	-71.46%
ROIC Less NNEP Spread (ROIC-NNEP)	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-164.34%	-48.07%	-36.35%
Return on Net Nonoperating Assets (RNNOA)	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	114.61%	22.33%	15.96%
Return on Equity (ROE)	-37.16%	-39.04%	-58.94%	-40.41%	-51.64%	-54.34%	-53.55%	-70.61%	-81.91%	-57.48%	-55.50%
Cash Return on Invested Capital (CROIC)	-6,157.59%	-9,772.32%	-23,263.99%	0.00%	0.00%	-807.53%	-979.92%	-1,308.81%	-369.25%	-103.43%	-75.25%
Operating Return on Assets (OROA)	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-63.77%	-46.76%	-44.24%
Return on Assets (ROA)	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-61.49%	-44.02%	-42.88%
Return on Common Equity (ROCE)	-37.16%	-39.04%	-58.94%	-40.41%	-51.64%	-54.34%	-53.55%	-70.61%	-81.91%	-57.48%	-55.50%
Return on Equity Simple (ROE_SIMPLE)	-26.59%	-31.69%	-63.28%	-26.51%	-66.08%	-39.54%	-55.05%	-79.24%	-75.95%	-52.39%	0.00%
Net Operating Profit after Tax (NOPAT)	-20	-38	-65	-90	-145	-183	-240	-279	-322	-277	-282
NOPAT Margin	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-27,114.49%	-168.64%	-107.15%
Net Nonoperating Expense Percent (NNEP)	-10.98%	-11.36%	-17.35%	-11.01%	-13.60%	-16.28%	-16.64%	-21.64%	-32.18%	-31.74%	-35.11%
Return On Investment Capital (ROIC_SIMPLE)	-	-	-	-	-	-	-	-55.77%	-55.05%	-38.89%	-40.36%
Cost of Revenue to Revenue	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	904.54%	75.57%	65.72%
SG&A Expenses to Revenue	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	8,992.09%	93.26%	57.81%
R&D to Revenue	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	28,938.35%	172.08%	113.95%
Operating Expenses to Revenue	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	37,930.45%	265.35%	187.35%
Earnings before Interest and Taxes (EBIT)	-28	-54	-93	-128	-207	-262	-343	-399	-461	-395	-403
Earnings before Interest, Taxes, Depreciation and Amortization (EBITDA)	-27	-53	-92	-129	-202	-251	-323	-377	-431	-362	-363
Valuation Ratios	-	-	-	-	-	-	-	-	-	-	-
Price to Book Value (P/BV)	3.55	2.59	3.99	2.34	11.68	10.37	4.82	2.02	3.56	3.17	1.55
Price to Tangible Book Value (P/TBV)	3.55	2.59	3.99	2.34	11.68	10.37	4.82	2.02	5.86	5.27	2.58
Price to Revenue (P/Rev)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	1,749.89	13.75	4.11
Price to Earnings (P/E)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Dividend Yield	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Earnings Yield	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Enterprise Value to Invested Capital (EV/IC)	822.22	591.59	4,034.16	0.00	0.00	228.26	121.10	23.76	5.89	4.99	1.96
Enterprise Value to Revenue (EV/Rev)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	1,515.35	11.78	2.99
Enterprise Value to EBITDA (EV/EBITDA)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Enterprise Value to EBIT (EV/EBIT)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Enterprise Value to NOPAT (EV/NOPAT)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Enterprise Value to Operating Cash Flow (EV/OCF)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Enterprise Value to Free Cash Flow (EV/FCFF)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Leverage & Solvency	-	-	-	-	-	-	-	-	-	-	-
Debt to Equity	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Long-Term Debt to Equity	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Financial Leverage	-1.00	-1.00	-1.00	-1.00	-1.01	-0.98	-0.96	-0.96	-0.70	-0.46	-0.44
Leverage Ratio	1.02	1.02	1.05	1.04	1.08	1.17	1.21	1.29	1.33	1.31	1.29
Compound Leverage Factor	1.01	1.01	1.04	1.00	1.03	1.15	1.21	1.28	1.29	1.24	1.26
Debt to Total Capital	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.16%	0.20%	0.17%	0.14%	0.14%
Short-Term Debt to Total Capital	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.14%
Long-Term Debt to Total Capital	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.16%	0.20%	0.17%	0.14%	0.00%
Preferred Equity to Total Capital	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Noncontrolling Interests to Total Capital	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Common Equity to Total Capital	100.00%	100.00%	100.00%	100.00%	100.00%	100.00%	99.84%	99.80%	99.83%	99.86%	99.86%
Debt to EBITDA	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Net Debt to EBITDA	0.00	0.00	0.00	0.00	0.00	0.00	1.56	1.27	0.65	0.89	0.81
Long-Term Debt to EBITDA	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Debt to NOPAT	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Net Debt to NOPAT	0.00	0.00	0.00	0.00	0.00	0.00	2.10	1.71	0.87	1.17	1.05
Long-Term Debt to NOPAT	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Altman Z-Score	134.84	50.95	32.11	43.90	42.54	34.75	8.62	-0.91	1.13	2.29	-1.99
Noncontrolling Interest Sharing Ratio	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Liquidity Ratios	-	-	-	-	-	-	-	-	-	-	-
Current Ratio	63.79	34.12	15.56	33.02	8.10	11.59	5.69	5.24	2.79	3.74	3.20
Quick Ratio	63.62	33.51	15.15	32.54	7.86	11.47	5.65	5.16	2.54	3.21	2.74
Cash Flow Metrics	-	-	-	-	-	-	-	-	-	-	-
Free Cash Flow to Firm (FCFF)	-20	-38	-65	-87	-139	-219	-233	-281	-606	-359	-297
Operating Cash Flow to CapEx	-1,608.14%	-2,147.80%	-7,656.52%	-8,451.50%	-2,297.08%	-438.40%	-606.65%	-1,433.33%	-1,623.24%	-3,188.88%	-893.75%
Free Cash Flow to Firm to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Operating Cash Flow to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Operating Cash Flow Less CapEx to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Efficiency Ratios	-	-	-	-	-	-	-	-	-	-	-
Asset Turnover	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.19	0.29
Accounts Receivable Turnover	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	4.72	3.47
Inventory Turnover	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	4.01	3.36
Fixed Asset Turnover	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.01	1.47	2.19
Accounts Payable Turnover	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.36	4.09	6.97
Days Sales Outstanding (DSO)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	77.30	105.13
Days Inventory Outstanding (DIO)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	91.09	108.75
Days Payable Outstanding (DPO)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	1,013.48	89.24	52.34
Cash Conversion Cycle (CCC)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	-1,013.48	79.15	161.54
Capital & Investment Metrics	-	-	-	-	-	-	-	-	-	-	-
Invested Capital	0.32	0.45	0.11	-2.33	-8.11	27	21	22	306	388	403
Invested Capital Turnover	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.01	0.47	0.67
Increase / (Decrease) in Invested Capital	0.39	0.13	-0.34	-2.44	-5.78	35	-6.48	1.79	283	82	15
Enterprise Value (EV)	266	265	436	622	3,186	6,177	2,492	531	1,802	1,933	788
Market Capitalization	369	432	581	1,090	3,493	6,806	2,995	1,009	2,081	2,255	1,084
Book Value per Share	$2.17	$2.69	$2.00	$3.78	$2.37	$4.48	$3.96	$3.17	$2.28	$2.33	$1.76
Tangible Book Value per Share	$2.17	$2.69	$2.00	$3.78	$2.37	$4.48	$3.96	$3.17	$1.39	$1.40	$1.06
Total Capital	104	167	145	466	299	656	623	501	586	711	700
Total Debt	0.00	0.00	0.00	0.00	0.00	0.00	1.00	1.00	1.00	1.00	1.00
Total Long-Term Debt	0.00	0.00	0.00	0.00	0.00	0.00	1.00	1.00	1.00	1.00	0.00
Net Debt	-104	-166	-145	-469	-307	-629	-503	-477	-279	-323	-296
Capital Expenditures (CapEx)	1.14	1.52	1.03	1.20	6.92	47	38	20	22	11	34
Debt-free, Cash-free Net Working Capital (DFCFNWC)	-1.35	-1.93	-5.68	-7.55	-30	-48	-86	-91	-82	11	8.35
Debt-free Net Working Capital (DFNWC)	102	165	140	461	277	581	419	388	198	335	305
Net Working Capital (NWC)	102	165	140	461	277	581	419	388	198	335	304
Net Nonoperating Expense (NNE)	8.16	15	27	34	53	76	102	117	122	95	109
Net Nonoperating Obligations (NNO)	-104	-166	-145	-469	-307	-629	-601	-477	-279	-323	-296
Total Depreciation and Amortization (D&A)	1.00	0.90	0.97	-0.38	4.70	11	20	22	30	33	40
Debt-free, Cash-free Net Working Capital to Revenue	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-6,923.89%	6.64%	3.17%
Debt-free Net Working Capital to Revenue	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	16,614.13%	203.98%	115.87%
Net Working Capital to Revenue	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	16,614.13%	203.98%	115.49%
Earnings Adjustments	-	-	-	-	-	-	-	-	-	-	-
Adjusted Basic Earnings per Share	($0.62)	($1.85)	($1.41)	($1.27)	($1.59)	($1.88)	($2.23)	($2.49)	($1.89)	($1.28)	($1.09)
Adjusted Weighted Average Basic Shares Outstanding	48.57M	62.31M	89.45M	123.42M	126.50M	146.98M	153.41M	159.26M	235.13M	289.88M	357.35M
Adjusted Diluted Earnings per Share	($0.62)	($1.85)	($1.41)	($1.27)	($1.59)	($1.88)	($2.23)	($2.49)	($1.89)	($1.28)	($1.09)
Adjusted Weighted Average Diluted Shares Outstanding	48.57M	62.31M	89.45M	123.42M	126.50M	146.98M	153.41M	159.26M	235.13M	289.88M	357.35M
Adjusted Basic & Diluted Earnings per Share	($0.62)	($1.85)	($1.41)	($1.27)	($1.59)	($1.88)	$0.00	$0.00	$0.00	$0.00	$0.00
Adjusted Weighted Average Basic & Diluted Shares Outstanding	44.41M	55.27M	65.24M	97.28M	124.34M	138.30M	157.17M	224.24M	279.31M	327.88M	411.96M
Normalized Net Operating Profit after Tax (NOPAT)	-20	-38	-65	-90	-145	-183	-240	-279	-322	-277	-279
Normalized NOPAT Margin	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-27,114.49%	-168.64%	-105.79%
Pre Tax Income Margin	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	-37,638.02%	-228.56%	-149.16%
Debt Service Ratios	-	-	-	-	-	-	-	-	-	-	-
EBIT to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
NOPAT to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
EBIT Less CapEx to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
NOPAT Less CapEx to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Payout Ratios	-	-	-	-	-	-	-	-	-	-	-
Dividend Payout Ratio	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Augmented Payout Ratio	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

This table displays calculated financial ratios and metrics derived from Iovance Biotherapeutics' official financial filings.

Metric	Q3 2023	Q4 2023	Q1 2024	Q2 2024	Q3 2024	Q4 2024	Q1 2025	Q2 2025	Q3 2025	Q4 2025	Q1 2026
Period end date	9/30/2023	12/31/2023	3/31/2024	6/30/2024	9/30/2024	12/31/2024	3/31/2025	6/30/2025	9/30/2025	12/31/2025	3/31/2026
DEI Shares Outstanding	-	-	-	-	-	-	-	-	-	-	411,961,607.00
DEI Adjusted Shares Outstanding	-	-	-	-	-	-	-	-	-	-	411,961,607.00
DEI Earnings Per Adjusted Shares Outstanding	-	-	-	-	-	-	-	-	-	-	-0.19
Growth Metrics	-	-	-	-	-	-	-	-	-	-	-
Revenue Growth	0.00%	0.00%	0.00%	12,969.75%	12,385.07%	15,189.21%	6,798.46%	92.73%	15.20%	17.75%	44.82%
EBITDA Growth	-15.20%	-11.07%	-3.78%	8.39%	26.42%	31.44%	-1.95%	-11.00%	-4.11%	13.89%	36.19%
EBIT Growth	-17.90%	-13.29%	-6.19%	7.42%	24.75%	28.60%	-2.97%	-11.64%	-6.55%	15.15%	33.14%
NOPAT Growth	-17.90%	-13.29%	-6.19%	7.42%	24.75%	28.60%	-2.97%	-11.64%	-6.55%	15.15%	33.14%
Net Income Growth	-14.20%	-10.50%	-5.22%	8.85%	26.56%	32.50%	-2.82%	-14.99%	-9.23%	8.47%	31.95%
EPS Growth	26.98%	29.23%	16.00%	27.66%	39.13%	47.83%	14.29%	2.94%	0.00%	0.00%	47.22%
Operating Cash Flow Growth	-32.10%	-8.11%	-22.51%	-4.77%	29.86%	12.71%	15.20%	31.48%	-33.45%	28.28%	30.49%
Free Cash Flow Firm Growth	-584.98%	-380.06%	-424.93%	42.77%	65.88%	61.31%	52.13%	27.10%	26.84%	53.40%	67.18%
Invested Capital Growth	1,014.83%	1,267.20%	805.60%	36.10%	20.19%	26.78%	28.33%	11.59%	6.77%	3.86%	0.18%
Revenue Q/Q Growth	97.06%	2.77%	48.34%	4,250.49%	88.24%	25.85%	-33.07%	21.55%	12.52%	28.64%	-17.68%
EBITDA Q/Q Growth	-7.23%	-3.43%	2.75%	15.07%	13.87%	3.61%	-44.61%	7.54%	18.21%	26.82%	-15.43%
EBIT Q/Q Growth	-7.52%	-2.45%	2.91%	13.43%	12.61%	2.80%	-40.02%	6.14%	16.59%	22.59%	-10.32%
NOPAT Q/Q Growth	-7.52%	-2.45%	2.91%	13.43%	12.61%	2.80%	-40.02%	6.14%	16.59%	22.59%	-10.32%
Net Income Q/Q Growth	-6.79%	-2.30%	2.92%	14.05%	13.96%	5.96%	-47.87%	3.88%	18.27%	21.20%	-9.93%
EPS Q/Q Growth	2.13%	0.00%	8.70%	19.05%	17.65%	14.29%	-50.00%	8.33%	0.00%	0.00%	0.00%
Operating Cash Flow Q/Q Growth	10.50%	0.13%	-45.62%	19.50%	40.09%	-24.29%	-41.47%	34.96%	-16.69%	33.21%	-37.11%
Free Cash Flow Firm Q/Q Growth	-26.99%	0.02%	0.71%	54.60%	24.30%	-13.37%	-22.86%	30.86%	24.02%	27.78%	13.48%
Invested Capital Q/Q Growth	19.60%	-2.52%	4.14%	12.10%	5.62%	2.83%	5.41%	-2.52%	1.05%	0.03%	1.67%
Profitability Metrics	-	-	-	-	-	-	-	-	-	-	-
Gross Margin	-825.37%	-805.60%	-915.52%	-0.84%	31.99%	38.20%	-0.85%	5.48%	42.96%	67.38%	40.50%
EBITDA Margin	-23,349.47%	-23,499.79%	-15,405.59%	-300.74%	-137.60%	-105.38%	-227.68%	-173.20%	-125.91%	-71.63%	-100.45%
Operating Margin	-25,236.89%	-25,156.85%	-16,464.62%	-327.63%	-152.11%	-117.48%	-245.76%	-189.78%	-140.69%	-84.66%	-113.46%
EBIT Margin	-25,236.89%	-25,156.85%	-16,464.62%	-327.63%	-152.11%	-117.48%	-245.76%	-189.78%	-140.69%	-84.66%	-113.46%
Profit (Net Income) Margin	-24,255.86%	-24,145.02%	-15,800.84%	-312.16%	-142.67%	-106.60%	-235.51%	-186.25%	-135.28%	-82.87%	-110.66%
Tax Burden Percent	98.92%	98.51%	98.77%	98.52%	98.21%	102.02%	98.44%	101.81%	97.43%	100.26%	99.17%
Interest Burden Percent	97.16%	97.43%	97.16%	96.71%	95.50%	88.94%	97.34%	96.39%	98.69%	97.63%	98.36%
Effective Tax Rate	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Return on Invested Capital (ROIC)	-73.09%	-127.63%	-124.13%	-24.28%	-28.02%	-38.92%	-100.66%	-84.97%	-63.28%	-39.52%	-55.47%
ROIC Less NNEP Spread (ROIC-NNEP)	-64.57%	-119.30%	-117.98%	-17.20%	-22.42%	-32.95%	-91.97%	-75.97%	-56.15%	-32.90%	-48.82%
Return on Net Nonoperating Assets (RNNOA)	43.91%	83.20%	87.01%	9.29%	11.72%	15.31%	45.79%	36.86%	26.49%	14.45%	22.02%
Return on Equity (ROE)	-29.18%	-44.43%	-37.12%	-14.98%	-16.30%	-23.61%	-54.86%	-48.11%	-36.79%	-25.07%	-33.45%
Cash Return on Invested Capital (CROIC)	-349.91%	-369.25%	-345.31%	-134.42%	-105.50%	-103.43%	-101.61%	-87.08%	-81.35%	-75.25%	-62.34%
Operating Return on Assets (OROA)	-25.52%	-41.42%	-37.00%	-12.47%	-14.99%	-22.80%	-56.92%	-48.98%	-37.16%	-24.47%	-34.25%
Return on Assets (ROA)	-24.53%	-39.75%	-35.51%	-11.88%	-14.06%	-20.69%	-54.55%	-48.06%	-35.73%	-23.95%	-33.40%
Return on Common Equity (ROCE)	-29.18%	-44.43%	-37.12%	-14.98%	-16.30%	-23.61%	-54.86%	-48.11%	-36.79%	-25.07%	-33.45%
Return on Equity Simple (ROE_SIMPLE)	-64.24%	0.00%	-66.12%	-57.28%	-53.01%	0.00%	-48.88%	0.00%	0.00%	0.00%	0.00%
Net Operating Profit after Tax (NOPAT)	-83	-85	-82	-71	-62	-61	-85	-80	-66	-51	-57
NOPAT Margin	-17,665.82%	-17,609.79%	-11,525.23%	-229.34%	-106.47%	-82.24%	-172.04%	-132.84%	-98.48%	-59.26%	-79.42%
Net Nonoperating Expense Percent (NNEP)	-8.51%	-8.33%	-6.16%	-7.08%	-5.60%	-5.97%	-8.69%	-9.00%	-7.13%	-6.62%	-6.64%
Return On Investment Capital (ROIC_SIMPLE)	-	-14.49%	-	-	-	-8.52%	-11.04%	-11.39%	-9.45%	-7.35%	-7.85%
Cost of Revenue to Revenue	925.37%	905.60%	1,015.52%	100.84%	68.01%	61.80%	100.85%	94.52%	57.04%	32.62%	59.50%
SG&A Expenses to Revenue	5,749.25%	6,203.94%	4,390.63%	127.20%	67.55%	57.68%	89.05%	62.88%	51.23%	41.65%	54.53%
R&D to Revenue	18,662.26%	18,147.30%	11,158.46%	199.59%	116.55%	98.01%	155.87%	132.38%	111.44%	79.35%	87.48%
Operating Expenses to Revenue	24,411.51%	24,351.24%	15,549.09%	326.79%	184.10%	155.68%	244.92%	195.26%	183.65%	152.04%	153.96%
Earnings before Interest and Taxes (EBIT)	-118	-121	-118	-102	-89	-87	-121	-114	-95	-73	-81
Earnings before Interest, Taxes, Depreciation and Amortization (EBITDA)	-110	-113	-110	-94	-81	-78	-112	-104	-85	-62	-72
Valuation Ratios	-	-	-	-	-	-	-	-	-	-	-
Price to Book Value (P/BV)	1.67	3.56	5.58	2.92	3.68	3.17	1.42	0.82	1.12	1.55	2.00
Price to Tangible Book Value (P/TBV)	2.50	5.86	9.83	4.74	6.11	5.27	2.26	1.43	1.88	2.58	3.19
Price to Revenue (P/Rev)	1,594.60	1,749.89	1,991.97	68.48	31.37	13.75	5.13	2.38	3.14	4.11	5.06
Price to Earnings (P/E)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Dividend Yield	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Earnings Yield	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Enterprise Value to Invested Capital (EV/IC)	2.45	5.89	10.78	5.13	6.51	4.99	1.79	0.69	1.21	1.96	2.77
Enterprise Value to Revenue (EV/Rev)	1,084.88	1,515.35	1,802.04	55.92	27.00	11.78	3.44	1.14	1.94	2.99	3.97
Enterprise Value to EBITDA (EV/EBITDA)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Enterprise Value to EBIT (EV/EBIT)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Enterprise Value to NOPAT (EV/NOPAT)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Enterprise Value to Operating Cash Flow (EV/OCF)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Enterprise Value to Free Cash Flow (EV/FCFF)	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Leverage & Solvency	-	-	-	-	-	-	-	-	-	-	-
Debt to Equity	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Long-Term Debt to Equity	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Financial Leverage	-0.68	-0.70	-0.74	-0.54	-0.52	-0.46	-0.50	-0.49	-0.47	-0.44	-0.45
Leverage Ratio	1.31	1.33	1.26	1.28	1.27	1.31	1.27	1.28	1.28	1.29	1.27
Compound Leverage Factor	1.27	1.30	1.22	1.24	1.22	1.16	1.23	1.23	1.27	1.26	1.25
Debt to Total Capital	0.15%	0.17%	0.15%	0.13%	0.13%	0.14%	0.13%	0.14%	0.14%	0.14%	0.14%
Short-Term Debt to Total Capital	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.13%	0.14%	0.14%	0.14%	0.14%
Long-Term Debt to Total Capital	0.15%	0.17%	0.15%	0.13%	0.13%	0.14%	0.00%	0.00%	0.00%	0.00%	0.00%
Preferred Equity to Total Capital	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Noncontrolling Interests to Total Capital	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Common Equity to Total Capital	99.85%	99.83%	99.85%	99.87%	99.87%	99.86%	99.87%	99.86%	99.86%	99.86%	99.86%
Debt to EBITDA	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Net Debt to EBITDA	0.86	0.65	0.83	0.97	1.00	0.89	0.99	0.80	0.79	0.81	0.97
Long-Term Debt to EBITDA	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Debt to NOPAT	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Net Debt to NOPAT	1.15	0.87	1.11	1.28	1.32	1.17	1.29	1.04	1.03	1.05	1.23
Long-Term Debt to NOPAT	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Altman Z-Score	0.63	2.56	8.54	3.82	4.85	3.41	-0.04	-2.14	-1.53	-0.80	0.39
Noncontrolling Interest Sharing Ratio	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Liquidity Ratios	-	-	-	-	-	-	-	-	-	-	-
Current Ratio	4.21	2.79	4.63	5.15	4.22	3.74	4.18	3.27	3.41	3.20	3.60
Quick Ratio	3.97	2.54	4.28	4.74	3.84	3.21	3.51	2.80	2.92	2.74	3.05
Cash Flow Metrics	-	-	-	-	-	-	-	-	-	-	-
Free Cash Flow to Firm (FCFF)	-368	-368	-366	-166	-126	-142	-175	-121	-92	-66	-57
Operating Cash Flow to CapEx	-2,350.66%	-2,379.43%	-2,931.65%	-22,269.00%	-2,577.49%	-1,758.54%	-1,669.52%	-903.99%	-725.77%	-564.00%	-1,090.71%
Free Cash Flow to Firm to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Operating Cash Flow to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Operating Cash Flow Less CapEx to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Efficiency Ratios	-	-	-	-	-	-	-	-	-	-	-
Asset Turnover	0.00	0.00	0.00	0.04	0.10	0.19	0.23	0.26	0.26	0.29	0.30
Accounts Receivable Turnover	0.00	0.00	0.00	2.07	0.00	4.72	5.98	5.28	4.09	3.47	3.74
Inventory Turnover	0.00	0.00	0.00	2.52	3.47	4.01	4.00	4.94	4.40	3.36	2.79
Fixed Asset Turnover	0.01	0.01	0.02	0.29	0.81	1.47	1.90	2.07	2.09	2.19	2.35
Accounts Payable Turnover	0.29	0.36	0.63	1.84	3.25	4.09	6.14	7.32	6.32	6.97	5.25
Days Sales Outstanding (DSO)	0.00	0.00	0.00	176.18	0.00	77.30	61.07	69.17	89.29	105.13	97.57
Days Inventory Outstanding (DIO)	0.00	0.00	0.00	144.87	105.28	91.09	91.17	73.93	82.91	108.75	130.75
Days Payable Outstanding (DPO)	1,243.20	1,013.48	580.16	198.84	112.30	89.24	59.41	49.89	57.78	52.34	69.57
Cash Conversion Cycle (CCC)	-1,243.20	-1,013.48	-580.16	122.21	-7.02	79.15	92.83	93.22	114.42	161.54	158.75
Capital & Investment Metrics	-	-	-	-	-	-	-	-	-	-	-
Invested Capital	314	306	318	357	377	388	409	398	402	403	409
Invested Capital Turnover	0.00	0.01	0.01	0.11	0.26	0.47	0.59	0.64	0.64	0.67	0.70
Increase / (Decrease) in Invested Capital	286	283	283	95	63	82	90	41	26	15	0.72
Enterprise Value (EV)	767	1,802	3,431	1,833	2,454	1,933	733	274	485	788	1,134
Market Capitalization	1,127	2,081	3,793	2,244	2,850	2,255	1,092	574	785	1,084	1,446
Book Value per Share	$2.72	$2.28	$2.55	$2.75	$2.55	$2.33	$2.34	$2.09	$1.94	$1.76	$1.75
Tangible Book Value per Share	$1.82	$1.39	$1.45	$1.69	$1.54	$1.40	$1.47	$1.20	$1.15	$1.06	$1.10
Total Capital	675	586	681	770	774	711	769	699	703	700	723
Total Debt	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00	1.00
Total Long-Term Debt	1.00	1.00	1.00	1.00	1.00	1.00	0.00	0.00	0.00	0.00	0.00
Net Debt	-360	-279	-362	-412	-396	-323	-359	-300	-300	-296	-312
Capital Expenditures (CapEx)	3.58	3.53	4.17	0.44	2.29	4.17	6.21	7.46	11	9.32	6.61
Debt-free, Cash-free Net Working Capital (DFCFNWC)	-70	-82	-60	-24	-17	11	31	-6.84	3.50	8.35	25
Debt-free Net Working Capital (DFNWC)	292	198	302	389	381	335	391	294	304	305	338
Net Working Capital (NWC)	292	198	302	389	381	335	390	293	303	304	337
Net Nonoperating Expense (NNE)	31	31	31	26	21	18	31	32	25	20	22
Net Nonoperating Obligations (NNO)	-360	-279	-362	-412	-396	-323	-359	-300	-300	-296	-312
Total Depreciation and Amortization (D&A)	8.85	7.99	7.57	8.37	8.49	8.92	8.92	9.94	9.97	11	9.30
Debt-free, Cash-free Net Working Capital to Revenue	-9,864.64%	-6,923.89%	-3,167.33%	-73.23%	-18.67%	6.64%	14.43%	-2.83%	1.40%	3.17%	8.63%
Debt-free Net Working Capital to Revenue	41,249.08%	16,614.13%	15,878.10%	1,185.82%	418.81%	203.98%	183.82%	121.87%	121.52%	115.87%	118.37%
Net Working Capital to Revenue	41,249.08%	16,614.13%	15,878.10%	1,185.82%	418.81%	203.98%	183.35%	121.46%	121.12%	115.49%	118.02%
Earnings Adjustments	-	-	-	-	-	-	-	-	-	-	-
Adjusted Basic Earnings per Share	($0.46)	($0.46)	($0.42)	($0.34)	($0.28)	($0.24)	($0.36)	($0.33)	($0.25)	($0.15)	($0.19)
Adjusted Weighted Average Basic Shares Outstanding	245.82M	235.13M	266.22M	284.82M	303.27M	289.88M	322.87M	334.51M	364.04M	357.35M	418.51M
Adjusted Diluted Earnings per Share	($0.46)	($0.46)	($0.42)	($0.34)	($0.28)	($0.24)	($0.36)	($0.33)	$0.00	$0.00	($0.19)
Adjusted Weighted Average Diluted Shares Outstanding	245.82M	235.13M	266.22M	284.82M	303.27M	289.88M	322.87M	334.51M	396.97M	357.35M	418.51M
Adjusted Basic & Diluted Earnings per Share	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00	$0.00
Adjusted Weighted Average Basic & Diluted Shares Outstanding	255.92M	279.31M	279.83M	303.51M	304.78M	327.88M	333.93M	361.85M	396.97M	411.96M	446.50M
Normalized Net Operating Profit after Tax (NOPAT)	-83	-85	-82	-71	-62	-61	-85	-80	-63	-51	-57
Normalized NOPAT Margin	-17,665.82%	-17,609.79%	-11,525.23%	-229.34%	-106.47%	-82.24%	-172.04%	-132.84%	-93.14%	-59.26%	-79.42%
Pre Tax Income Margin	-24,520.90%	-24,509.96%	-15,997.76%	-316.85%	-145.27%	-104.49%	-239.24%	-182.93%	-138.85%	-82.65%	-111.59%
Debt Service Ratios	-	-	-	-	-	-	-	-	-	-	-
EBIT to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
NOPAT to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
EBIT Less CapEx to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
NOPAT Less CapEx to Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Payout Ratios	-	-	-	-	-	-	-	-	-	-	-
Dividend Payout Ratio	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
Augmented Payout Ratio	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials Breakdown Chart

Key Financial Trends

IOVANCE BIOTHERAPEUTICS, INC. (IOVA) has shown a mix of improving gross margin and rising revenue in 2025, but remains deeply levered to ongoing financing and a heavy R&D spend. Below are the top trends based on the last four years of quarterly results.

Q4 2025 revenue and gross margin improve meaningfully. Revenue reached 86.77 million with a total gross profit of 58.47 million, giving an estimated gross margin around 67%, a substantial improvement versus 2024’s margin.
Sequential 2025 revenue growth throughout the year. Revenue rose from 49.32M (Q1) to 59.95M (Q2) to 67.46M (Q3) to 86.77M (Q4), signaling stronger top-line momentum in 2025.
Financing activity provided liquidity in multiple quarters. Net cash from financing activities was positive in several quarters (e.g., Q1 2025 +143.3M; Q3 2025 +88.1M; Q4 2025 +56.2M), helping fund operations amid losses.
Investing cash flow turned modestly positive in mid-2025. Net cash from continuing investing activities was +17.0M in Q3 2025 and remained near breakeven in Q4 2025, contributing to liquidity.
Solid short-term liquidity in mid-2025. Total current assets hovered around 429 million in Q3 2025, with cash around 158 million and current liabilities roughly 126 million, implying a healthy near-term liquidity position.
R&D and SG&A remain a large, ongoing burn. RD expenses (e.g., ~68.9M–79.4M in 2025) and SG&A (approximately 36–43M) dominate operating costs relative to revenue, underscoring continued cash burn typical of biotech Phase 2/3 programs.
Equity financing and dilution are a recurring theme. Recurrent issuance of common equity across several quarters (e.g., Q4 2025 issuance of 56.6M, Q3 2025 issuance of 88.5M) supports liquidity but implies ongoing dilution risk for shareholders.
Low long-term debt and modest leverage. Long-Term Debt is typically zero or minimal across 2025, indicating low fixed-cost leverage relative to assets.
Intangible assets are substantial, with ongoing investment tap. Intangible assets in the hundreds of millions (e.g., 285–306M range in 2025 balance sheets) reflect pipeline and collaboration investments, but also potential impairment risk if milestones aren’t met.
Net income remains negative across quarters. Attributable net income to common shareholders was deeply in the red (e.g., -71.9M in Q4 2025; -91.3M in Q3 2025; -111.7M in Q2 2025; -116.2M in Q1 2025), indicating ongoing profitability challenges.

05/12/26 04:11 AM ETAI Generated. May Contain Errors.

Iovance Biotherapeutics Financials - Frequently Asked Questions

According to the most recent income statement we have on file, Iovance Biotherapeutics' financial year ends in December. Their financial year 2025 ended on December 31, 2025.

Iovance Biotherapeutics' net income appears to be on an upward trend, with a most recent value of -$390.98 million in 2025, rising from -$27.66 million in 2015. The previous period was -$372.18 million in 2024. View Iovance Biotherapeutics' forecast to see where analysts expect Iovance Biotherapeutics to go next.

Iovance Biotherapeutics' total operating income in 2025 was -$403.36 million, based on the following breakdown:

Total Gross Profit: $90.32 million
Total Operating Expenses: $493.67 million

Over the last 10 years, Iovance Biotherapeutics' total revenue changed from $0.00 in 2015 to $263.50 million in 2025, a change of 26,350,200,000.0%.

Iovance Biotherapeutics' total liabilities were at $214.59 million at the end of 2025, a 7.3% increase from 2024, and a 13,064.8% increase since 2015.

In the past 10 years, Iovance Biotherapeutics' cash and equivalents has ranged from $13.97 million in 2019 to $231.73 million in 2022, and is currently $163.08 million as of their latest financial filing in 2025.

Over the last 10 years, Iovance Biotherapeutics' book value per share changed from 2.17 in 2015 to 1.76 in 2025, a change of -19.1%.

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Financial statements for NASDAQ:IOVA last updated on 5/8/2026 by MarketBeat.com Staff. New filings and market data are monitored continuously.

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Iovance Biotherapeutics (IOVA) Financials

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Iovance Biotherapeutics (IOVA) Financials

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Iovance Biotherapeutics Financials - Frequently Asked Questions

When does Iovance Biotherapeutics' fiscal year end?

How has Iovance Biotherapeutics' net income changed over the last 10 years?

What is Iovance Biotherapeutics' operating income?

How has Iovance Biotherapeutics' revenue changed over the last 10 years?

How much debt does Iovance Biotherapeutics have?

How much cash does Iovance Biotherapeutics have?

How has Iovance Biotherapeutics' book value per share changed over the last 10 years?

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