Puma Biotechnology (PBYI) Short Interest Ratio & Short Volume $3.45 -0.02 (-0.58%) Closing price 04:00 PM EasternExtended Trading$3.40 -0.05 (-1.33%) As of 05:13 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Puma Biotechnology Short Interest DataPuma Biotechnology (PBYI) has a short interest of 2.63 million shares, representing 7.05% of the float (the number of shares available for trading by the public). This marks a -1.87% decrease in short interest from the previous month. The short interest ratio (days to cover) is 7.4, indicating that it would take 7.4 days of the average trading volume of 413,438 shares to cover all short positions.Current Short Interest2,630,000 sharesPrevious Short Interest2,680,000 sharesChange Vs. Previous Month-1.87%Dollar Volume Sold Short$9.02 millionShort Interest Ratio7.4 Days to CoverLast Record DateJune 30, 2025Outstanding Shares49,630,000 sharesFloat Size37,280,000 sharesShort Percent of Float7.05%Today's Trading Volume302,655 sharesAverage Trading Volume413,438 sharesToday's Volume Vs. Average73% Short Selling Puma Biotechnology? Sign up to receive the latest short interest report for Puma Biotechnology and its competitors with MarketBeat's FREE newsletter. Email Address Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartPBYI Short Interest Over TimePBYI Days to Cover Over TimePBYI Percentage of Float Shorted Over Time Puma Biotechnology Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 6/30/20252,630,000 shares $9.02 million -1.9%7.1%7.4 $3.43 6/15/20252,680,000 shares $8.98 million -3.6%7.2%7.8 $3.35 5/31/20252,780,000 shares $9.26 million -3.1%7.4%7.5 $3.33 5/15/20252,870,000 shares $9.41 million -2.1%7.7%7.2 $3.28 4/30/20252,930,000 shares $9.32 million +2.1%7.5%7.9 $3.18 4/15/20252,870,000 shares $8.50 million -0.4%7.4%7.7 $2.96 3/31/20252,880,000 shares $8.52 million +3.2%7.4%5.9 $2.96 3/15/20252,790,000 shares $9.26 million -11.7%7.2%5.2 $3.32 2/28/20253,160,000 shares $11.31 million +2.9%8.1%5.8 $3.58 2/15/20253,070,000 shares $8.78 million +3.0%8.0%6.2 $2.86 Get the Latest News and Ratings for PBYI and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Puma Biotechnology and its competitors with MarketBeat's FREE daily newsletter. 1/31/20252,980,000 shares $8.61 million -2.9%8.5%5 $2.89 1/15/20253,070,000 shares $9.42 million +2.0%8.8%5.3 $3.07 12/31/20243,010,000 shares $9.18 million +3.4%8.6%5.8 $3.05 12/15/20242,910,000 shares $8.38 million +3.6%8.4%7.2 $2.88 11/30/20242,810,000 shares $9.53 million -5.7%8.1%7.2 $3.39 11/15/20242,980,000 shares $7.21 million -6.6%8.6%8.2 $2.42 10/31/20243,190,000 shares $9.09 million -11.9%9.1%9.2 $2.85 10/15/20243,620,000 shares $10.32 million +6.2%10.3%11.2 $2.85 9/30/20243,410,000 shares $8.70 million -5.8%9.7%9.8 $2.55 9/15/20243,620,000 shares $9.16 million +4.0%10.3%7.6 $2.53 8/31/20243,480,000 shares $8.70 million -13.0%10.0%7.3 $2.50 8/15/20244,000,000 shares $10.60 million +4.7%11.5%8.6 $2.65 7/31/20243,820,000 shares $13.69 million +0.5%10.8%8 $3.59 7/15/20243,800,000 shares $13.91 million +29.7%10.9%8.2 $3.66 6/30/20242,930,000 shares $9.55 million +8.5%8.4%6.5 $3.26 6/15/20242,700,000 shares $8.40 million +7.6%7.6%7.4 $3.11 5/31/20242,510,000 shares $9.66 million -17.4%7.1%6.1 $3.85 5/15/20243,040,000 shares $14.14 million -2.3%8.6%5.8 $4.65 4/30/20243,110,000 shares $15.77 million -6.6%9.0%5.4 $5.07 4/15/20243,330,000 shares $17.82 million +1.2%9.6%5.9 $5.35 3/31/20243,290,000 shares $17.44 million -1.2%9.5%5.4 $5.30 3/15/20243,330,000 shares $16.65 million -18.6%9.0%5.5 $5.00 2/29/20244,090,000 shares $25.44 million +13.9%11.0%7.8 $6.22 2/15/20243,590,000 shares $25.09 million +11.8%9.8%7.9 $6.99 1/31/20243,210,000 shares $15.09 million +6.3%8.7%9 $4.70 1/15/20243,020,000 shares $14.95 million +4.1%8.1%9.4 $4.95 12/31/20232,900,000 shares $12.56 million +5.1%7.8%11.1 $4.33 12/15/20232,760,000 shares $10.82 million +35.3%7.4%12.4 $3.92 11/30/20232,040,000 shares $7.96 million +8.5%5.5%10.1 $3.90 11/15/20231,880,000 shares $7.14 million +9.3%5.1%11.1 $3.80Bitcoin Beats Gold — But This Coin Could Beat Them Both (Ad)Bitcoin just hit a record high—but it’s not the top crypto play right now. Crypto analyst Juan Villaverde, who called Bitcoin’s breakout to $100K nearly to the day, says a lesser-known coin could be even bigger. It’s faster, cheaper, and backed by Google, Visa, and top VCs with over $200 million already invested.Get the name of this “third pillar” crypto in Juan’s free report → 10/31/20231,720,000 shares $4.23 million -1.2%4.6%12 $2.46 10/15/20231,740,000 shares $4.11 million -0.6%4.7%13.5 $2.36 9/30/20231,750,000 shares $4.60 million +1.2%4.7%12.6 $2.63 9/15/20231,730,000 shares $5.29 million +3.6%4.7%10.4 $3.06 8/31/20231,670,000 shares $6.06 million +2.5%4.5%9.3 $3.63 8/15/20231,630,000 shares $5.85 million +0.6%4.1%8 $3.59 7/31/20231,620,000 shares $5.86 million -2.4%4.1%7.6 $3.62 7/15/20231,660,000 shares $5.53 million +3.8%4.3%7.8 $3.33 6/30/20231,600,000 shares $5.65 million +11.1%4.1%7.2 $3.53 6/15/20231,440,000 shares $5.11 million +5.9%3.7%5.9 $3.55 5/31/20231,360,000 shares $4.56 million No Change3.4%4.8 $3.35 5/15/20231,360,000 shares $4.00 million -1.5%3.4%4.5 $2.94 4/30/20231,380,000 shares $3.70 million +7.0%3.6%4.5 $2.68 4/15/20231,290,000 shares $3.90 million No Change3.3%4.1 $3.02 3/31/20231,290,000 shares $3.99 million +8.4%3.3%3.9 $3.09 3/15/20231,190,000 shares $2.88 million +3.5%3.1%3.4 $2.42 2/28/20231,150,000 shares $4.44 million +2.7%3.0%3.2 $3.86 2/15/20231,120,000 shares $4.76 million +6.7%3.0%3.1 $4.25 1/31/20231,050,000 shares $4.52 million +12.2%2.8%2.5 $4.30 1/15/2023935,800 shares $4.51 million +6.3%2.5%2.4 $4.82 12/30/2022880,500 shares $3.72 million -38.0%2.3%2.4 $4.23 12/15/20221,420,000 shares $6.97 million -5.3%3.7%4.4 $4.91 11/30/20221,500,000 shares $6.78 million +0.7%3.9%5.7 $4.52 11/15/20221,490,000 shares $5.07 million -2.0%3.9%6.4 $3.40 10/31/20221,520,000 shares $3.31 million No Change3.9%8.5 $2.18 10/15/20221,520,000 shares $3.39 million -5.0%3.9%8.2 $2.23 9/30/20221,600,000 shares $3.79 million -9.6%4.2%7.7 $2.37 9/15/20221,770,000 shares $4.53 million -2.2%4.6%5.8 $2.56 8/31/20221,810,000 shares $4.85 million -1.1%4.7%5.1 $2.68 8/15/20221,830,000 shares $6.31 million +2.2%4.7%4.6 $3.45 7/31/20221,790,000 shares $5.24 million -3.8%4.7%4 $2.93 7/15/20221,860,000 shares $5.86 million -7.5%4.9%4.1 $3.15 6/30/20222,010,000 shares $5.73 million -41.7%5.3%4.4 $2.85 6/15/20223,450,000 shares $10.52 million -1.2%9.1%7.1 $3.05 5/31/20223,490,000 shares $6.77 million +4.8%9.3%8.3 $1.94 5/15/20223,330,000 shares $6.09 million +4.7%8.9%7.4 $1.83 4/30/20223,180,000 shares $7.50 million +2.9%9.2%7.4 $2.36 4/15/20223,090,000 shares $8.74 million -1.6%9.0%7.1 $2.83 3/31/20223,140,000 shares $9.04 million +10.6%9.1%5.7 $2.88 3/15/20222,840,000 shares $7.72 million +21.4%8.2%5.2 $2.72 2/28/20222,340,000 shares $5.38 million +1.7%6.4%3.9 $2.30 2/15/20222,300,000 shares $5.31 million -6.5%6.4%3.7 $2.31 1/31/20222,460,000 shares $6.05 million -4.3%6.8%3.4 $2.46 1/15/20222,570,000 shares $7.14 million -13.5%7.1%3.2 $2.78 12/31/20212,970,000 shares $9.03 million +6.5%8.3%4.3 $3.04 12/15/20212,790,000 shares $8.40 million -10.0%8.0%4 $3.01 11/30/20213,100,000 shares $9.61 million +22.5%8.9%4.8 $3.10 11/15/20212,530,000 shares $9.31 million +4.1%7.2%4.4 $3.68 10/29/20212,430,000 shares $12.39 million -2.8%7.0%4.8 $5.10 10/15/20212,500,000 shares $15.13 million -7.8%7.2%5.8 $6.05Bitcoin Beats Gold — But This Coin Could Beat Them Both (Ad)Bitcoin just hit a record high—but it’s not the top crypto play right now. Crypto analyst Juan Villaverde, who called Bitcoin’s breakout to $100K nearly to the day, says a lesser-known coin could be even bigger. It’s faster, cheaper, and backed by Google, Visa, and top VCs with over $200 million already invested.Get the name of this “third pillar” crypto in Juan’s free report → 9/30/20212,710,000 shares $19.00 million -5.2%7.8%6.7 $7.01 9/15/20212,860,000 shares $19.91 million -0.4%8.2%6.8 $6.96 8/31/20212,870,000 shares $21.73 million -2.4%8.2%6.8 $7.57 8/13/20212,940,000 shares $21.34 million -4.6%8.4%7.1 $7.26 7/30/20213,080,000 shares $23.16 million +6.6%8.9%7.8 $7.52 7/15/20212,890,000 shares $23.67 million +7.0%8.5%8.6 $8.19 6/30/20212,700,000 shares $24.79 million -28.4%7.9%7.8 $9.18 6/15/20213,770,000 shares $39.89 million -2.3%11.0%12.4 $10.58 5/28/20213,860,000 shares $40.72 million -6.1%11.3%13.9 $10.55 5/14/20214,110,000 shares $39.83 million -0.2%12.0%13.6 $9.69 4/30/20214,120,000 shares $40.99 million -10.4%12.1%12.5 $9.95 4/15/20214,600,000 shares $46.87 million -5.7%13.6%12.5 $10.19 3/31/20214,880,000 shares $45.77 million -0.2%14.5%12.9 $9.38 3/15/20214,890,000 shares $55.21 million +0.2%14.5%11.8 $11.29 2/26/20214,880,000 shares $51.48 million +3.6%14.5%10.2 $10.55 2/12/20214,710,000 shares $58.88 million -4.3%14.0%9.1 $12.50 1/29/20214,920,000 shares $57.96 million +0.8%14.6%9.2 $11.78 1/15/20214,880,000 shares $53.68 million -27.0%14.5%8.9 $11.00 12/31/20206,680,000 shares $69.41 million -14.5%19.8%11.8 $10.39 12/15/20207,810,000 shares $85.13 million +0.9%23.2%13.2 $10.90 11/30/20207,740,000 shares $90.79 million -4.2%23.0%13.2 $11.73 11/15/20208,080,000 shares $72.15 million +1.0%24.0%14 $8.93 10/30/20208,000,000 shares $72.80 million +2.2%24.3%13.6 $9.10 10/15/20207,830,000 shares $76.11 million +7.7%23.8%11.1 $9.72 9/30/20207,270,000 shares $73.35 million -1.5%N/A9.9 $10.09 9/15/20207,380,000 shares $73.73 million -0.9%22.5%9.2 $9.99 8/31/20207,450,000 shares $76.66 million +1.5%22.7%8.3 $10.29 8/14/20207,340,000 shares $72.15 million +3.8%22.4%7.6 $9.83 7/31/20207,070,000 shares $72.89 million +2.5%21.2%6.7 $10.31 PBYI Short Interest - Frequently Asked Questions What is Puma Biotechnology's current short interest? Short interest is the volume of Puma Biotechnology shares that have been sold short but have not yet been closed out or covered. As of June 30th, traders have sold 2,630,000 shares of PBYI short. 7.05% of Puma Biotechnology's shares are currently sold short. Learn More on Puma Biotechnology's current short interest. What is a good short interest ratio for Puma Biotechnology? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. PBYI shares currently have a short interest ratio of 7.0. Learn More on Puma Biotechnology's short interest ratio. Which institutional investors are shorting Puma Biotechnology? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Puma Biotechnology: Simplex Trading LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. What is a good short interest percentage for Puma Biotechnology? Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 7.05% of Puma Biotechnology's floating shares are currently sold short. Is Puma Biotechnology's short interest increasing or decreasing? Puma Biotechnology saw a drop in short interest in the month of June. As of June 30th, there was short interest totaling 2,630,000 shares, a drop of 1.9% from the previous total of 2,680,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. What is Puma Biotechnology's float size? Puma Biotechnology currently has issued a total of 49,630,000 shares. Some of Puma Biotechnology's outstanding shares are available for trading, while others are subject to various restrictions. The public float, also referred to as floating shares or "the float", are shares that publicly owned, unrestricted and available to trade on the open market. Puma Biotechnology currently has a public float of 37,280,000 shares. How does Puma Biotechnology's short interest compare to its competitors? 7.05% of Puma Biotechnology's shares are currently sold short. Here is how the short interest of companies in the industry of "pharmaceutical products" compare to Puma Biotechnology: ADMA Biologics Inc (7.05%), CytomX Therapeutics, Inc. (29.73%), Entrada Therapeutics, Inc. (5.60%), Maravai LifeSciences Holdings, Inc. (13.29%), Iovance Biotherapeutics, Inc. (35.65%), Urogen Pharma (42.26%), Tilray Brands, Inc. (20.64%), Tango Therapeutics, Inc. (35.96%), Stoke Therapeutics, Inc. (23.34%), Prime Medicine, Inc. (39.00%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: SPDR S&P 500 ETF Trust ($72.10 billion), Invesco QQQ ($26.89 billion), iShares Russell 2000 ETF ($19.61 billion), MicroStrategy Incorporated ($9.52 billion), iShares 20+ Year Treasury Bond ETF ($8.70 billion), WD-40 Company ($7.66 billion), Technology Select Sector SPDR Fund ($6.10 billion), Invesco S&P 500 Equal Weight ETF ($5.80 billion), Invesco S&P 500 Top 50 ETF ($5.53 billion), and Vanguard Large-Cap ETF ($5.35 billion). View all of the most shorted stocks. What does it mean to sell short Puma Biotechnology stock? Short selling PBYI is an investing strategy that aims to generate trading profit from Puma Biotechnology as its price is falling. PBYI shares are trading down $0.02 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Puma Biotechnology? A short squeeze for Puma Biotechnology occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of PBYI, which in turn drives the price of the stock up even further. How often is Puma Biotechnology's short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including PBYI, twice per month. The most recent reporting period available is June, 30 2025. More Short Interest Resources from MarketBeat Related Companies ADMA Biologics Short Squeeze CytomX Therapeutics Short Squeeze Entrada Therapeutics Short Squeeze Maravai LifeSciences Short Squeeze Iovance Biotherapeutics Short Squeeze Urogen Pharma Short Squeeze Tilray Brands Short Squeeze Tango Therapeutics Short Squeeze Stoke Therapeutics Short Squeeze Prime Medicine Short Squeeze Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:PBYI) was last updated on 7/23/2025 by MarketBeat.com Staff From Our PartnersINVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting OffRight now, we’re witnessing a monumental shift in the world.Traders Agency | SponsoredAltucher: Turn $900 into $108,000 in just 12 months?Bitcoin is breaking out — and one state just created a Strategic Crypto Reserve. 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