NASDAQ:PMN Promis Neurosciences (PMN) Stock Price, News & Analysis $10.15 -0.26 (-2.50%) Closing price 04:00 PM EasternExtended Trading$10.57 +0.42 (+4.14%) As of 07:31 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Promis Neurosciences Stock (NASDAQ:PMN) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Promis Neurosciences alerts:Sign Up Key Stats Today's Range$9.91▼$10.6450-Day Range$9.83▼$17.7752-Week Range$6.27▼$39.75Volume38,709 shsAverage Volume27,709 shsMarket Capitalization$91.05 millionP/E RatioN/ADividend YieldN/APrice Target$26.50Consensus RatingModerate Buy Company Overview Promis Neurosciences, Inc. is a clinical‐stage biopharmaceutical company focused on the discovery and development of novel therapeutics for central nervous system disorders. The company’s research programs target cognitive impairment and other neurological symptoms associated with diseases such as Alzheimer’s disease and multiple sclerosis. Leveraging a proprietary small‐molecule discovery platform, Promis Neurosciences advances both preclinical and early clinical candidates designed to modulate neural pathways involved in memory, learning and neuroinflammation. The company’s pipeline reflects a commitment to addressing unmet needs in neurology by optimizing compound profiles for safety, selectivity and central nervous system penetration. Promis Neurosciences collaborates with academic institutions and industry partners to accelerate its research and development efforts. These strategic alliances support biomarker identification, translational studies and clinical trial design, aiming to streamline candidate advancement and enrich patient selection strategies. The company is headquartered in the United States and its common stock trades on the Nasdaq stock exchange under the symbol PMN.AI Generated. May Contain Errors. Read More Promis Neurosciences Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks63rd Percentile Overall ScorePMN MarketRank™: Promis Neurosciences scored higher than 63% of companies evaluated by MarketBeat, and ranked 363rd out of 869 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.6 / 5Analyst RatingModerate Buy Consensus RatingPromis Neurosciences has received a consensus rating of Moderate Buy. The company's average rating score is 2.75, and is based on 1 strong buy rating, 2 buy ratings, no hold ratings, and 1 sell rating.Upside PotentialPromis Neurosciences has a consensus price target of $26.50, representing about 161.1% upside from its current price of $10.15.Amount of Analyst CoveragePromis Neurosciences has only been the subject of 1 research reports in the past 90 days.Read more about Promis Neurosciences' stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthN/A Price to Earnings Ratio vs. the MarketThe P/E ratio of Promis Neurosciences is -0.70, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Promis Neurosciences is -0.70, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Read more about Promis Neurosciences' valuation and earnings. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted1.89% of the float of Promis Neurosciences has been sold short.Short Interest Ratio / Days to CoverPromis Neurosciences has a short interest ratio ("days to cover") of 4.64.Change versus previous monthShort interest in Promis Neurosciences has recently increased by 17.95%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldPromis Neurosciences does not currently pay a dividend.Dividend GrowthPromis Neurosciences does not have a long track record of dividend growth. News and Social Media2.9 / 5News Sentiment0.63 News SentimentPromis Neurosciences has a news sentiment score of 0.63. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.78 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 3 news articles for Promis Neurosciences this week, compared to 2 articles on an average week.Search InterestOnly 1 people have searched for PMN on MarketBeat in the last 30 days. This is a decrease of 0% compared to the previous 30 days.MarketBeat Follows1 people have added Promis Neurosciences to their MarketBeat watchlist in the last 30 days. Company Ownership4.2 / 5Insider TradingAcquiring Shares Cluster Insider Buying2 insiders have purchased shares of Promis Neurosciences in the last three months. Multiple insiders buying is a strong bullish signal.Net Insider BuyingOver the last three months, insiders have purchased a net $115,850.00 in company stock, which represents 0.1272% of the company's market cap.Insider Buying vs. Insider SellingIn the past three months, Promis Neurosciences insiders have bought more of their company's stock than they have sold. Specifically, they have bought $115,850.00 in company stock and sold $0.00 in company stock.Percentage Held by Insiders1.50% of the stock of Promis Neurosciences is held by insiders.Percentage Held by Institutions50.13% of the stock of Promis Neurosciences is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Promis Neurosciences' insider trading history. Receive PMN Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Promis Neurosciences and its competitors with MarketBeat's FREE daily newsletter. 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PMN Stock News HeadlinesPromis Neurosciences (NASDAQ:PMN) Upgraded by Wall Street Zen to Sell RatingMay 31 at 1:09 AM | americanbankingnews.comProMIS Neurosciences to Participate in Upcoming Conferences in JuneMay 28, 2026 | globenewswire.comI paid $5,000 to hear Elon say thisOne investor paid $5,000 to be in a private room with Elon Musk in Los Angeles - and what he heard confirmed a conviction 15 years in the making. Musk is launching a project 27 years in the making that could be his biggest move yet. One analyst believes there is a single stock positioned to benefit most - and he is giving away the name for free.June 2 at 1:00 AM | InvestorPlace (Ad)Promis Neurosciences (NASDAQ:PMN) Receives Average Recommendation of "Moderate Buy" from AnalystsMay 24, 2026 | americanbankingnews.comProMIS Neurosciences (PMN) Receives a Buy from GuggenheimMay 20, 2026 | theglobeandmail.comProMIS Neurosciences Inc.: ProMIS Neurosciences Announces First Quarter 2026 Financial Results and Provides Corporate HighlightsMay 12, 2026 | finanznachrichten.deProMIS Neurosciences Announces First Quarter 2026 Financial Results and Provides Corporate HighlightsMay 12, 2026 | globenewswire.comProMIS Neurosciences (PMN) price target decreased by 57.76% to 35.06March 28, 2026 | msn.comSee More Headlines PMN Stock Analysis - Frequently Asked Questions How have PMN shares performed this year? Promis Neurosciences' stock was trading at $6.8250 at the start of the year. Since then, PMN shares have increased by 48.7% and is now trading at $10.15. How were Promis Neurosciences' earnings last quarter? Promis Neurosciences (NASDAQ:PMN) announced its quarterly earnings data on Tuesday, May, 12th. The company reported ($1.26) earnings per share (EPS) for the quarter, missing analysts' consensus estimates of ($1.06) by $0.20. When did Promis Neurosciences' stock split? Promis Neurosciences's stock reverse split on Friday, November 28th 2025.A 1-25 reverse split was announced. The number of shares owned by shareholders was adjusted after the closing bell on Thursday, November 27th 2025. An investor that had 100 shares of stock prior to the reverse split would have 4 shares after the split. Who are Promis Neurosciences' major shareholders? Top institutional investors of Promis Neurosciences include Janus Henderson Group PLC (14.41%), Ally Bridge Group NY LLC (4.62%), Yu Fan (3.68%) and ADAR1 Capital Management LLC (1.06%). Insiders that own company stock include Abg Management Ltd, Eugene Williams, Madge K Shafmaster, Patrick D Kirwin, Johanne Kaplan, Max A Milbury and Neil Cashman. View institutional ownership trends. How do I buy shares of Promis Neurosciences? Shares of PMN stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Promis Neurosciences own? Based on aggregate information from My MarketBeat watchlists, some other companies that Promis Neurosciences investors own include PayPal (PYPL), Recursion Pharmaceuticals (RXRX), Pacific Biosciences of California (PACB), Editas Medicine (EDIT), Trimble (TRMB). Company Calendar Last Earnings5/12/2026Today6/02/2026Jefferies Global Healthcare Conference 20266/04/2026Next Earnings (Estimated)8/12/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Yellow Zone (1m+) 1-Year History Jun 25 Sep 25 Dec 25 Mar 26 Jun 26 PMN's financial health is in the Yellow zone, according to TradeSmith. PMN has been in this zone for over one month. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:PMN CIK1374339 Webwww.promisneurosciences.com Phone(416) 847-6898FaxN/AEmployees5Year Founded2001Price Target and Rating Average Price Target for Promis Neurosciences$26.50 High Price Target$35.00 Low Price Target$18.00 Potential Upside/Downside+161.1%Consensus RatingModerate Buy Rating Score (0-4)2.75 Research Coverage4 Analysts Profitability EPS (Trailing Twelve Months)($14.51) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$39.72 million Net MarginsN/A Pretax MarginN/A Return on Equity-237.99% Return on Assets-151.04% Debt Debt-to-Equity RatioN/A Current Ratio9.92 Quick Ratio9.92 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value($0.58) per share Price / Book-17.50Miscellaneous Outstanding Shares8,970,000Free Float8,833,000Market Cap$91.05 million OptionableNot Optionable Beta-0.19 Social Links 5G Stocks: The Path Forward is ProfitableClick the link to see MarketBeat's guide to investing in 5G and which 5G stocks show the most promise. 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