NASDAQ:PSNL Personalis (PSNL) Stock Price, News & Analysis $16.46 -0.11 (-0.66%) Closing price 09/25/2026 04:00 PM EasternExtended Trading$16.61 +0.15 (+0.92%) As of 09/25/2026 07:55 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Personalis Stock (NASDAQ:PSNL) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Personalis alerts:Sign Up Key Stats Today's Range$16.38▼$16.7750-Day Range$11.73▼$18.3852-Week Range$4.95▼$18.89Volume1.01 million shsAverage Volume2.35 million shsMarket Capitalization$1.72 billionP/E RatioN/ADividend YieldN/APrice Target$14.54Consensus RatingHold Company Overview Personalis, Inc. is a genomics company focused on precision oncology and advanced molecular testing. The company develops and commercializes genomic products designed to help identify, monitor and characterize cancer, supporting more informed treatment decisions and the development of targeted therapies. Its offerings include tissue- and blood-based tumor profiling, liquid biopsy testing and immune profiling. Personalis’ technologies are designed to detect and track tumor-derived signals, evaluate genomic alterations and provide insights into the interaction between cancer and the immune system. These capabilities support pharmaceutical and biotechnology companies in drug discovery, clinical trials and biomarker development, as well as healthcare organizations involved in cancer care. Founded in 2011 and headquartered in Menlo Park, California, Personalis has worked with biopharmaceutical companies, academic medical centers and other research organizations. The company became publicly traded on the Nasdaq Stock Market in 2019. Its leadership includes Chief Executive Officer Chris Bauer, who oversees the company’s efforts to advance genomics-based tools for oncology research and patient management.AI Generated. May Contain Errors. Read More Personalis Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks39th Percentile Overall ScorePSNL MarketRank™: Personalis scored higher than 39% of companies evaluated by MarketBeat, and ranked 697th out of 907 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion2.2 / 5Analyst RatingHold Consensus RatingPersonalis has received a consensus rating of Hold. The company's average rating score is 2.30, and is based on no strong buy ratings, 4 buy ratings, 5 hold ratings, and 1 sell rating.Downside RiskPersonalis has a consensus price target of $14.54, representing about 11.7% downside from its current price of $16.46.Amount of Analyst CoveragePersonalis has been the subject of 8 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Personalis' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Personalis are expected to grow in the coming year, from ($1.07) to ($0.78) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Personalis is -15.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Personalis is -15.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioPersonalis has a P/B Ratio of 5.60. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Personalis' valuation and earnings. Short Interest3.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted8.24% of the float of Personalis has been sold short.Short Interest Ratio / Days to CoverPersonalis has a short interest ratio ("days to cover") of 3.55, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Personalis has recently decreased by 1.41%, indicating that investor sentiment is improving. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldPersonalis does not currently pay a dividend.Dividend GrowthPersonalis does not have a long track record of dividend growth. News and Social Media3.5 / 5News Sentiment0.56 News SentimentPersonalis has a news sentiment score of 0.56. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.72 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 16 news articles for Personalis this week, compared to 4 articles on an average week.Search Interest5 people have searched for PSNL on MarketBeat in the last 30 days. This is an increase of 400% compared to the previous 30 days.MarketBeat Follows4 people have added Personalis to their MarketBeat watchlist in the last 30 days. Company Ownership1.6 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Personalis insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $3,835,152.00 in company stock.Percentage Held by Insiders4.20% of the stock of Personalis is held by insiders.Percentage Held by Institutions61.91% of the stock of Personalis is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Personalis' insider trading history. Receive PSNL Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Personalis and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. PSNL Stock News HeadlinesPersonalis (NASDAQ:PSNL) SVP Sells $33,542.96 in StockSeptember 25 at 5:40 AM | americanbankingnews.comPersonalis (NASDAQ:PSNL) CFO Sells $47,540.82 in StockSeptember 25 at 5:40 AM | americanbankingnews.comWhy I went to Mount RushmoreA small miner just hit on gold in the hills surrounding Mount Rushmore, thanks to a breakthrough new technology. This could be one of the biggest gold finds since the 1870s, yet the stock still trades around 6 dollars. BlackRock and Vanguard have been quietly loading up on shares while most investors have missed the story. The same technology is unlocking hidden resource wealth across America, driving stocks up 227 percent, 378 percent, and even 773 percent.September 26 at 1:00 AM | Stansberry Research (Ad)Insider Selling: Personalis (NASDAQ:PSNL) CMO Sells $64,847.56 in StockSeptember 25 at 4:53 AM | americanbankingnews.comChristopher Hall Sells 7,459 Shares of Personalis (NASDAQ:PSNL) StockSeptember 24 at 4:52 AM | americanbankingnews.comBRODSKY & SMITH SHAREHOLDER UPDATE: Notifying Investors of the Following Investigations: Centerspace (NYSE – CSR), Fulcrum Therapeutics, Inc. (Nasdaq – FULC), Weave Communications, Inc. (NYSE – WEAV), Personalis, Inc. (Nasdaq – PSNL)September 23 at 5:41 PM | globenewswire.comStephen Michael Moore Sells 2,068 Shares of Personalis (NASDAQ:PSNL) StockSeptember 23 at 5:22 AM | insidertrades.comBRODSKY & SMITH SHAREHOLDER UPDATE: Notifying Investors of the Following Investigations: Personalis, Inc. (Nasdaq – PSNL), Werewolf Therapeutics, Inc. (Nasdaq – HOWL), Beazer Homes USA, Inc. (NYSE – BZH), MarketAxess Holdings Inc. (Nasdaq – MKTX)September 9, 2026 | globenewswire.comSee More Headlines PSNL Stock Analysis - Frequently Asked Questions How have PSNL shares performed this year? Personalis' stock was trading at $7.96 on January 1st, 2026. Since then, PSNL shares have increased by 106.8% and is now trading at $16.46. How were Personalis' earnings last quarter? Personalis, Inc. (NASDAQ:PSNL) posted its quarterly earnings data on Tuesday, August, 4th. The company reported ($0.30) earnings per share for the quarter, missing analysts' consensus estimates of ($0.26) by $0.04. The firm had revenue of $22.36 million for the quarter, compared to the consensus estimate of $16.69 million. Personalis had a negative net margin of 153.84% and a negative trailing twelve-month return on equity of 46.47%. When did Personalis IPO? Personalis (PSNL) raised $119 million in an initial public offering on Thursday, June 20th 2019. The company issued 7,921,500 shares at a price of $14.00-$16.00 per share. Morgan Stanley, BofA Merrill Lynch and Cowen and Company served as the underwriters for the IPO and Oppenheimer was co-manager. Who are Personalis' major shareholders? Personalis' top institutional investors include Merck & Co. Inc. (13.41%), BlackRock Inc. (6.76%), Bank of America Corp DE (1.74%) and AIGH Capital Management LLC (1.64%). Insiders that own company stock include Christopher M Hall, Aaron Tachibana, Richard Chen, Stephen Michael Moore and Stephen Michael Moore. View institutional ownership trends. How do I buy shares of Personalis? Shares of PSNL stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Personalis own? Based on aggregate information from My MarketBeat watchlists, some other companies that Personalis investors own include Digital Turbine (APPS), CrowdStrike (CRWD), Okta (OKTA), Unity Software (U) and Vuzix (VUZI). Company Calendar Last Earnings8/04/2026Today9/26/2026Next Earnings (Estimated)11/03/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (4m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 PSNL's financial health is in the Green zone, according to TradeSmith. PSNL has been in this zone for over 4 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Life Sciences Tools & Services Sub-IndustryLife Sciences Tools & Services Current SymbolNASDAQ:PSNL CIK1527753 Webwww.personalis.com Phone(650) 752-1300FaxN/AEmployees260Year Founded2011Price Target and Rating Average Price Target for Personalis$14.54 High Price Target$17.00 Low Price Target$10.00 Potential Upside/Downside-11.7%Consensus RatingHold Rating Score (0-4)2.30 Research Coverage10 Analysts Profitability EPS (Trailing Twelve Months)($1.09) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$81.27 million Net Margins-153.84% Pretax Margin-153.79% Return on Equity-46.47% Return on Assets-35.30% Debt Debt-to-Equity RatioN/A Current Ratio5.28 Quick Ratio5.08 Sales & Book Value Annual Sales$69.65 million Price / Sales24.75 Cash FlowN/A Price / Cash FlowN/A Book Value$2.94 per share Price / Book5.60Miscellaneous Outstanding Shares104,720,000Free Float100,323,000Market Cap$1.72 billion OptionableOptionable Beta2.31 Social Links The Infrastructure's Backbone: 10 Stocks Powering the AI BuildoutThe AI boom extends far beyond the biggest tech names. Discover 10 companies supplying the memory, storage, networking, semiconductor manufacturing, and power infrastructure that make AI possible. Learn where the next wave of AI investment opportunities may emerge—and the key risks investors should watch as the global AI buildout accelerates.Get This Free Report This page (NASDAQ:PSNL) was last updated on 9/26/2026 by MarketBeat.com Staff. From Our PartnersA letter from Shannon StansberryPorter Stansberry nearly canceled the entire project. When he first saw the claimed returns - only one down ye...Porter & Company | SponsoredMajor Buy Alert Issued for September 30thKeith Kaplan has invested $17 million into his own AI research tools, building a platform now used by 180,000 ...TradeSmith | SponsoredHere’s Why Trump Won’t End The Iran WarTrump has called an Iran deal close 38 times since the war began, yet the fighting keeps flaring back up. 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