Plus Therapeutics (PSTV) Short Interest Ratio & Short Volume $0.61 -0.07 (-9.69%) Closing price 04:00 PM EasternExtended Trading$0.62 +0.00 (+0.15%) As of 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock Plus Therapeutics Short Interest DataPlus Therapeutics (PSTV) has a short interest of 16.71 million shares. This marks a 310.57% increase in short interest from the previous month. The short interest ratio (days to cover) is 0.7, indicating that it would take 0.7 days of the average trading volume of 45.46 million shares to cover all short positions.Current Short Interest16,710,000 sharesPrevious Short Interest4,070,000 sharesChange Vs. Previous Month+310.57%Dollar Volume Sold Short$11.42 millionShort Interest Ratio0.7 Days to CoverLast Record DateSeptember 30, 2025Outstanding Shares99,260,000 sharesPercentage of Shares Shorted16.83%Today's Trading Volume8,870,458 sharesAverage Trading Volume45,463,132 sharesToday's Volume Vs. Average20% Short Selling Plus Therapeutics? Sign up to receive the latest short interest report for Plus Therapeutics and its competitors with MarketBeat's FREE newsletter. Email Address Get Report View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. 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Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartPSTV Short Interest Over TimePSTV Days to Cover Over TimePSTV Percentage of Float Shorted Over Time Plus Therapeutics Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 9/30/202516,710,000 shares $11.42 million +310.6%N/A0.7 $0.68 9/15/20254,070,000 shares $1.68 million -12.7%N/A0.1 $0.41 8/31/20254,660,000 shares $2.12 million +49.4%4.7%0.2 $0.46 8/15/20253,120,000 shares $1.96 million +67.7%N/A0.1 $0.63 7/31/20251,860,000 shares $898.38 thousand -50.3%3.1%0.1 $0.48 7/15/20253,740,000 shares $1.19 million -34.8%N/A0.1 $0.32 6/30/20255,740,000 shares $2.00 million +390.6%11.7%0.2 $0.35 6/15/20251,170,000 shares $367.38 thousand +128.0%7.2%0.1 $0.31 5/31/2025513,100 shares $145.16 thousand -85.3%9.2%0 $0.28 5/15/20253,490,000 shares $1.77 million +67.8%22.5%0.2 $0.51 Get the Latest News and Ratings for PSTV and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Plus Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 4/30/20252,080,000 shares $1.50 million +84.1%12.6%0.1 $0.72 4/15/20251,130,000 shares $735.63 thousand -9.6%6.8%0.1 $0.65 3/31/20251,250,000 shares $1.19 million +34.5%7.5%0.1 $0.95 3/15/2025929,600 shares $631.01 thousand +562.1%8.1%0.1 $0.68 2/28/2025140,400 shares $101.79 thousand +134.4%2.4%0 $0.73 2/15/202559,900 shares $74.28 thousand -32.2%1.0%1.1 $1.24 1/31/202588,400 shares $108.73 thousand -12.8%1.5%1.2 $1.23 1/15/2025101,400 shares $121.68 thousand -10.6%1.8%1.4 $1.20 12/31/2024113,400 shares $130.41 thousand +20.6%2.0%1.5 $1.15 12/15/202494,000 shares $119.38 thousand -17.5%1.6%1 $1.27 11/30/2024114,000 shares $145.92 thousand +9.6%2.0%1.3 $1.28 11/15/2024104,000 shares $121.68 thousand +98.9%1.8%1.3 $1.17 10/31/202452,300 shares $68.77 thousand -3.2%0.9%0.7 $1.32 10/15/202454,000 shares $76.14 thousand -43.4%0.9%0.9 $1.41 9/30/202495,400 shares $139.28 thousand +81.0%1.7%1.3 $1.46 9/15/202452,700 shares $78.00 thousand +51.0%0.9%1 $1.48 8/31/202434,900 shares $49.91 thousand -58.2%0.6%0.6 $1.43 8/15/202483,500 shares $116.90 thousand -35.3%1.4%1.4 $1.40 7/31/2024129,000 shares $232.20 thousand -39.3%2.3%2.2 $1.80 7/15/2024212,600 shares $389.06 thousand -9.2%3.8%2.4 $1.83 6/30/2024234,100 shares $344.13 thousand +14.0%4.2%3.1 $1.47 6/15/2024205,300 shares $410.60 thousand +19.9%3.7%2.7 $2.00 5/31/2024171,300 shares $378.57 thousand +6.5%3.1%2.4 $2.21 5/15/2024160,800 shares $373.06 thousand +248.8%2.9%2.2 $2.32 4/30/202446,100 shares $80.24 thousand -0.9%1.1%0.7 $1.74 4/15/202446,500 shares $80.91 thousand -0.6%1.1%1.5 $1.74 3/31/202446,800 shares $84.47 thousand +45.3%1.1%1.5 $1.81 3/15/202432,200 shares $55.71 thousand -21.1%0.8%0.9 $1.73 2/29/202440,800 shares $79.15 thousand -12.1%1.0%1.1 $1.94 2/15/202446,400 shares $92.34 thousand +7.2%1.0%1.2 $1.99 1/31/202443,300 shares $87.03 thousand -25.3%1.0%0.6 $2.01 1/15/202458,000 shares $120.06 thousand +21.9%1.3%0.2 $2.07 12/31/202347,600 shares $83.30 thousand -26.3%1.1%0.2 $1.75 12/15/202364,600 shares $123.39 thousand -25.5%1.5%0.2 $1.91 11/30/202386,700 shares $147.39 thousand -59.7%2.0%0.1 $1.70 11/15/2023215,000 shares $406.35 thousand +441.6%4.9%0.3 $1.89 10/31/202339,700 shares $48.43 thousand -43.8%0.9%0.1 $1.22 10/15/202370,600 shares $97.43 thousand -27.6%2.5%0.2 $1.38 9/30/202397,500 shares $130.65 thousand -30.6%3.4%0.2 $1.34 9/15/2023140,500 shares $195.30 thousand +347.5%5.0%0.3 $1.39 8/31/202331,400 shares $87.61 thousand -50.4%1.1%0.1 $2.79 8/15/202363,300 shares $153.82 thousand +76.8%2.2%1.5 $2.43 7/31/202335,800 shares $88.07 thousand +35.6%1.4%1 $2.46 7/15/202326,400 shares $54.65 thousand -13.2%1.1%0.8 $2.07 6/30/202330,400 shares $61.41 thousand -24.6%1.2%1 $2.02 6/15/202340,300 shares $122.51 thousand -3.8%1.6%1.5 $3.04 5/31/202341,900 shares $168.44 thousand -14.3%1.7%1.7 $4.02 5/15/202348,900 shares $213.69 thousand +154.7%2.0%1.9 $4.37 4/30/202319,200 shares $74.82 thousand -66.6%0.8%0.8 $3.90 4/15/202357,500 shares $15.94 thousand -76.7%N/A0.2 $0.28 3/31/2023247,100 shares $71.66 thousand -13.8%N/A0.9 $0.29 3/15/2023286,600 shares $80.39 thousand +4.1%N/A0.9 $0.28 2/28/2023275,400 shares $93.69 thousand -31.4%N/A0.8 $0.34 2/15/2023401,600 shares $156.62 thousand -14.9%N/A1.2 $0.39 1/31/2023472,000 shares $204.52 thousand +17.2%N/A1.4 $0.43 1/15/2023402,600 shares $192.52 thousand +39.7%N/A1.2 $0.48 12/30/2022288,200 shares $91.36 thousand -31.9%N/A0.7 $0.32 12/15/2022423,100 shares $132.01 thousand -5.0%N/A0.6 $0.31 11/30/2022445,200 shares $179.28 thousand -17.8%N/A0.5 $0.40 11/15/2022541,500 shares $234.96 thousand -11.4%N/A0.4 $0.43 10/31/2022610,900 shares $287.12 thousand -50.3%N/A0.1 $0.47 10/15/20221,230,000 shares $642.06 thousand +388.9%N/A0.3 $0.52 9/30/2022251,600 shares $111.96 thousand +74.0%N/A0.1 $0.45 9/15/2022144,600 shares $89.57 thousand -73.5%N/A0 $0.62 8/31/2022545,600 shares $457.98 thousand +865.7%N/A0.1 $0.84 8/15/202256,500 shares $32.04 thousand +289.7%N/A0 $0.57 7/31/202214,500 shares $7.18 thousand -67.5%N/A0.2 $0.49 7/15/202244,600 shares $22.64 thousand +117.6%0.4%0.4 $0.51 6/30/202220,500 shares $11.07 thousand +57.7%0.2%0.1 $0.54 6/15/202213,000 shares $7.28 thousand +106.4%0.1%0.1 $0.56 5/31/20226,300 shares $3.53 thousand -43.2%N/A0 $0.56 5/15/202211,100 shares $5.38 thousand -77.3%N/A0.1 $0.48 4/30/202248,900 shares $32.76 thousand -49.2%N/A0.2 $0.67 4/15/202296,300 shares $87.54 thousand +154.1%N/A0.3 $0.91 3/31/202237,900 shares $37.90 thousand -58.3%N/A0 $1.00 3/15/202290,900 shares $87.26 thousand -69.7%N/A0 $0.96 2/28/2022300,000 shares $312 thousand +11.4%N/A0.1 $1.04 2/15/2022269,400 shares $280.18 thousand -38.3%1.3%0.1 $1.04 1/31/2022436,400 shares $411.96 thousand +70.2%2.9%0.1 $0.94 1/15/2022256,400 shares $264.09 thousand +594.9%1.7%0.1 $1.03 12/31/202136,900 shares $38.75 thousand -0.3%N/A0 $1.05 12/15/202137,000 shares $44.40 thousand -62.7%0.3%0.1 $1.20 11/30/202199,100 shares $148.65 thousand -13.1%0.7%0.3 $1.50 11/15/2021114,000 shares $191.52 thousand +91.6%0.8%0.1 $1.68 10/29/202159,500 shares $113.05 thousand -47.9%0.4%0 $1.90 10/15/2021114,200 shares $199.85 thousand -28.5%0.8%0.1 $1.75 9/30/2021159,600 shares $304.84 thousand -66.0%1.1%0.1 $1.91 9/15/2021469,400 shares $868.39 thousand +121.0%3.1%0.3 $1.85 8/31/2021212,400 shares $414.18 thousand +41.7%1.4%0.2 $1.95 8/13/2021149,900 shares $311.79 thousand -40.8%1.3%0.3 $2.08 7/30/2021253,400 shares $481.46 thousand -14.1%2.1%0.6 $1.90 7/15/2021295,000 shares $660.80 thousand -9.7%2.9%0.3 $2.24 6/30/2021326,700 shares $836.35 thousand -3.9%3.2%0.3 $2.56 6/15/2021340,100 shares $925.07 thousand -65.0%3.7%0.3 $2.72 5/28/2021972,000 shares $2.30 million -28.5%10.7%0.8 $2.37 5/14/20211,360,000 shares $2.77 million +34.7%15.0%1.1 $2.04 4/30/20211,010,000 shares $2.41 million +103.3%11.3%0.6 $2.39 4/15/2021496,700 shares $1.09 million +30.9%5.6%0.5 $2.19 3/31/2021379,600 shares $903.45 thousand +125.3%4.2%0.4 $2.38 3/15/2021168,500 shares $500.45 thousand +12.4%1.9%0.2 $2.97 2/26/2021149,900 shares $449.70 thousand -2.9%1.7%0.2 $3.00 2/12/2021154,300 shares $524.62 thousand +2.7%3.4%0.2 $3.40 1/29/2021150,300 shares $371.24 thousand +440.7%3.3%0.4 $2.47 1/15/202127,800 shares $65.89 thousand -25.1%0.6%0.1 $2.37 12/31/202037,100 shares $77.54 thousand -52.8%0.8%0.1 $2.09 12/15/202078,600 shares $158.77 thousand +104.7%1.8%0.3 $2.02 11/30/202038,400 shares $82.18 thousand -65.5%0.9%0.1 $2.14 11/15/2020111,300 shares $254.88 thousand -29.2%2.5%0.1 $2.29 10/30/2020157,300 shares $353.93 thousand -28.6%3.5%0.2 $2.25 PSTV Short Interest - Frequently Asked Questions What is Plus Therapeutics' current short interest? Short interest is the volume of Plus Therapeutics shares that have been sold short but have not yet been closed out or covered. As of September 30th, traders have sold 16,710,000 shares of PSTV short. Learn More on Plus Therapeutics' current short interest. What is a good short interest ratio for Plus Therapeutics? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. PSTV shares currently have a short interest ratio of 1.0. Learn More on Plus Therapeutics's short interest ratio. Is Plus Therapeutics' short interest increasing or decreasing? Plus Therapeutics saw a increase in short interest in the month of September. As of September 30th, there was short interest totaling 16,710,000 shares, an increase of 310.6% from the previous total of 4,070,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. How does Plus Therapeutics' short interest compare to its competitors? Here is how the short interest of companies in the industry of "medical equipment" compare to Plus Therapeutics: Sanara MedTech Inc. (6.64%), Outset Medical, Inc. (10.12%), Monogram Orthopaedics Inc. (0.87%), Shoulder Innovations, Inc. (6.99%), Inogen, Inc (2.71%), TriSalus Life Sciences, Inc. (5.68%), CVRx, Inc. (11.84%), Nano-X Imaging Ltd. (11.32%), CapsoVision, Inc. (0.15%), InfuSystem Holdings, Inc. (1.33%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: AppLovin Corporation ($15.71 billion), Robinhood Markets, Inc. ($7.56 billion), Reddit Inc. ($4.55 billion), Coinbase Global, Inc. ($4.53 billion), CoreWeave Inc. ($4.43 billion), Charter Communications, Inc. ($4.07 billion), Seagate Technology Holdings PLC ($3.94 billion), IonQ, Inc. ($3.78 billion), TC Energy Corporation ($3.13 billion), and Live Nation Entertainment, Inc. ($3.12 billion). View all of the most shorted stocks. What does it mean to sell short Plus Therapeutics stock? Short selling PSTV is an investing strategy that aims to generate trading profit from Plus Therapeutics as its price is falling. PSTV shares are trading down $0.07 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Plus Therapeutics? A short squeeze for Plus Therapeutics occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of PSTV, which in turn drives the price of the stock up even further. How often is Plus Therapeutics' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including PSTV, twice per month. The most recent reporting period available is September, 30 2025. More Short Interest Resources from MarketBeat Related Companies Sanara MedTech Short Squeeze Outset Medical Short Squeeze Monogram Orthopaedics Short Squeeze Shoulder Innovations Short Squeeze Inogen Short Squeeze TriSalus Life Sciences Short Squeeze CVRx Short Squeeze Nano-X Imaging Short Squeeze CapsoVision Short Squeeze InfuSystem Short Squeeze Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:PSTV) was last updated on 10/16/2025 by MarketBeat.com Staff From Our PartnersOctober 16 Changes the Microchip Game — and InvestingWhile everyone's chasing the same AI plays, George Gilder is focused on something completely different. 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