This company has been marked as potentially delisted and may not be actively trading. Regulus Therapeutics (RGLS) Institutional Ownership Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsEarningsFDA EventsHeadlinesInsider TradesOwnershipShort InterestTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Regulus Therapeutics (NASDAQ:RGLS)CurrentInstitutional OwnershipPercentage92.38%Number ofInstitutional Buyers(last 12 months)23TotalInstitutional Inflows(last 12 months)$27.18MNumber ofInstitutional Sellers(last 12 months)13TotalInstitutional Outflows(last 12 months)$20.44M Get RGLS Insider Trade Alerts Want to know when executives and insiders are buying or selling Regulus Therapeutics stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily. 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Skip Chart & View Institutional Buying and Selling Data RGLS Institutional Buying and Selling by Quarter Regulus Therapeutics Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails6/27/2025 Goldman Sachs Group Inc.130,339$228K0.0%-38.6%0.188% 6/18/2025 Voya Investment Management LLC21,368$37K0.0%-7.4%0.031% 5/29/2025 Rhumbline Advisers57,744$101K0.0%-3.0%0.083% 5/16/2025 Octagon Capital Advisors LP4,637,076$8.12M0.9%-4.4%6.698% 5/16/2025 Goldman Sachs Group Inc.130,339$228K0.0%-38.6%0.188% 5/16/2025 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.38,345$67K0.0%+4.5%0.055% 5/16/2025 AQR Capital Management LLC68,580$120K0.0%N/A0.099% 5/16/2025 Alyeska Investment Group L.P.937,500$1.64M0.0%-9.6%1.354% 5/15/2025 Baker BROS. Advisors LP2,694,044$4.72M0.1%N/A4.067% 5/15/2025 DAFNA Capital Management LLC847,176$1.48M0.4%-3.2%1.279% Get the Latest News and Ratings for RGLS and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Regulus Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 5/15/2025 Velan Capital Investment Management LP80,000$140K0.1%+14.3%0.121% 5/15/2025 Driehaus Capital Management LLC958,345$1.68M0.0%N/A1.447% 5/12/2025 Nuveen LLC85,602$150K0.0%N/A0.129% 5/12/2025 Vivo Capital LLC2,696,426$4.72M0.6%-46.1%4.071% 5/8/2025 Federated Hermes Inc.15,819,863$27.69M0.1%+23.1%23.882% 5/2/2025 Victory Capital Management Inc.386,666$677K0.0%-0.8%0.584% 4/23/2025 Tyche Wealth Partners LLC121,589$213K0.0%+14.6%0.184% 4/23/2025 Oppenheimer & Co. Inc.55,000$96K0.0%N/A0.083% 2/17/2025 Velan Capital Investment Management LP70,000$111K0.1%N/A0.107% 2/17/2025 Octagon Capital Advisors LP4,848,802$7.66M1.3%+13.7%7.403% 2/17/2025 Millennium Management LLC2,192,158$3.46M0.0%+69.7%3.347% 2/17/2025 DAFNA Capital Management LLC875,200$1.38M0.4%-2.2%1.336% 2/14/2025 RA Capital Management L.P.336,843$532K0.0%-56.1%0.514% 2/14/2025 Northern Trust Corp457,233$722K0.0%-8.1%0.698% 2/14/2025 Price T Rowe Associates Inc. MD29,597$47K0.0%-98.6%0.045% 2/13/2025 PEAK6 LLC60,000$95K0.0%N/A0.092% 2/13/2025 Barclays PLC96,247$152K0.0%+13.9%0.147% 2/13/2025 Renaissance Technologies LLC117,100$185K0.0%+20.5%0.179% 2/12/2025 JPMorgan Chase & Co.190,457$301K0.0%+141.2%0.291% 2/6/2025 Victory Capital Management Inc.389,886$616K0.0%-2.3%0.595% 1/30/2025 Rhumbline Advisers59,531$94K0.0%-20.1%0.091% 12/26/2024 JPMorgan Chase & Co.78,972$124K0.0%+193.4%0.121% 11/19/2024 Barclays PLC84,477$132K0.0%+285.2%0.129% 11/16/2024 Geode Capital Management LLC1,280,567$2.01M0.0%-4.0%1.955% 11/15/2024 Barclays PLC84,477$132K0.0%+285.2%0.129% 11/15/2024 Jane Street Group LLC29,580$46K0.0%N/A0.045% 11/15/2024 State Street Corp1,000,998$1.57M0.0%+3.5%1.528% 11/15/2024 RA Capital Management L.P.766,834$1.20M0.0%-87.7%1.171% 11/15/2024 Point72 Asset Management L.P.893,762$1.40M0.0%N/A1.365% 11/14/2024 NEA Management Company LLC6,467,802$10.15M0.6%N/A9.875% This Coin Could Explode, and it’s Hiding in Plain Sight! 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Sometimes the biggest opportunities are hiding in plain sight...Click here to discover The #1 Coin To Own Right Now.11/13/2024 FMR LLC328,157$515K0.0%-83.8%0.501% 11/13/2024 The Manufacturers Life Insurance Company129,700$204K0.0%N/A0.198% 11/5/2024 Victory Capital Management Inc.398,866$626K0.0%+10.4%0.609% 10/25/2024 Tyche Wealth Partners LLC106,089$167K0.0%+920.6%0.162% 10/11/2024 Creative Planning16,466$26K0.0%N/A0.025% 10/3/2024 SG Americas Securities LLC20,800$33K0.0%N/A0.032% 8/15/2024CVI Holdings LLC401,012$716K0.6%-71.5%0.613% 8/9/2024 Renaissance Technologies LLC118,100$211K0.0%+56.4%0.180% 8/5/2024 Victory Capital Management Inc.361,386$645K0.0%-1.8%0.552% 8/1/2024 Rhumbline Advisers76,472$136K0.0%N/A0.117% 7/26/2024 Bank of New York Mellon Corp197,193$352K0.0%N/A0.301% 5/29/2024 Opaleye Management Inc.170,308$490K0.1%N/A0.260% 5/17/2024 RA Capital Management L.P.6,250,000$18M0.2%N/A9.547% 5/15/2024 NEA Management Company LLC6,467,802$18.63M1.1%N/A9.879% 5/10/2024 Vanguard Group Inc.740,215$2.13M0.0%+158.4%1.131% 5/7/2024CVI Holdings LLC1,406,250$4.05M3.9%N/A2.148% 4/22/2024 Vivo Capital LLC5,000,000$14.40M1.1%N/A7.638% 2/5/2024 Victory Capital Management Inc.271,736$348K0.0%+16.5%1.344% 11/13/2023 FMR LLC2,922,600$4.03M0.0%+32.4%14.454% 11/6/2023 Victory Capital Management Inc.233,207$322K0.0%+5.3%1.197% 8/14/2023 Prelude Capital Management LLC40,660$60K0.0%N/A0.209% 9/16/2022 Federated Hermes Inc.2,904,826$6.01M0.0%-90.0%19.850% 8/16/2022 DAFNA Capital Management LLC555,555$1.15M0.3%-90.0%3.797% 8/12/2022 Ikarian Capital LLC105,341$217K0.0%-91.8%0.722% 8/1/2022 Victory Capital Management Inc.221,506$459K0.0%-90.1%1.517% 7/19/2022 Commonwealth Equity Services LLC22,000$45K0.0%-83.2%0.151% 2/14/2022 DAFNA Capital Management LLC5,555,555$1.75M0.4%N/A6.382% 1/19/2022Asymmetry Capital Management L.P.2,731,044$860K0.5%+94.9%3.137% 11/15/2021 GSA Capital Partners LLP64,708$45K0.0%-68.6%0.074% 11/4/2021Asymmetry Capital Management L.P.1,401,491$968K0.6%-3.4%1.610% 10/29/2021 Commonwealth Equity Services LLC111,000$76K0.0%+38.8%0.128% 9/17/2021 Virtu Financial LLC79,193$64K0.0%N/A0.091% 8/27/2021Endurant Capital Management LP2,607,674$2.12M0.6%+9.7%2.996% 8/16/2021 State Street Corp176,494$144K0.0%N/A0.203% 8/13/2021 Geode Capital Management LLC589,196$479K0.0%+54.3%0.786% 8/13/2021 Vanguard Group Inc.3,095,237$2.52M0.0%-3.9%4.131% 8/12/2021 Lido Advisors LLC57,500$47K0.0%N/A0.077% 8/11/2021 Commonwealth Equity Services LLC80,000$65K0.0%+300.0%0.107% 8/10/2021Strategic Wealth Advisors Group LLC74,800$61K0.0%N/A0.100% 8/5/2021 GSA Capital Partners LLP206,265$168K0.0%N/A0.275% (Data available from 1/1/2016 forward) RGLS Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of RGLS shares? During the previous two years, 38 institutional investors and hedge funds held shares of Regulus Therapeutics. The most heavily invested institutionals were Federated Hermes Inc. ($27.69M), NEA Management Company LLC ($10.15M), Octagon Capital Advisors LP ($8.12M), Vivo Capital LLC ($4.72M), Baker BROS. Advisors LP ($4.72M), Millennium Management LLC ($3.46M), and Vanguard Group Inc. ($2.13M).Learn more on Regulus Therapeutics' institutional investors. What percentage of Regulus Therapeutics' stock is owned by institutional investors? 92.38% of Regulus Therapeutics' stock is owned by institutional investors. Learn more on RGLS's institutional investor holdings. Which institutional investors have been buying Regulus Therapeutics' stock? Of the 31 institutional investors that purchased Regulus Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: NEA Management Company LLC ($12.94M), RA Capital Management L.P. ($6.25M), Vivo Capital LLC ($5M), Federated Hermes Inc. ($2.97M), Baker BROS. Advisors LP ($2.69M), CVI Holdings LLC ($1.41M), and Driehaus Capital Management LLC ($958.35K). How much institutional buying is happening at Regulus Therapeutics? Institutional investors have bought a total of 16,516,860 shares in the last 24 months. This purchase volume represents approximately $27.18M in transactions. Which of Regulus Therapeutics' major shareholders have been selling company stock? Of the 13 institutional investors that sold Regulus Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: RA Capital Management L.P. ($5.91M), Vivo Capital LLC ($2.30M), Price T Rowe Associates Inc. MD ($2.12M), FMR LLC ($1.69M), Octagon Capital Advisors LP ($211.73K), Goldman Sachs Group Inc. ($164.08K), and Alyeska Investment Group L.P. ($100K). How much institutional selling is happening at Regulus Therapeutics? Institutional investors have sold a total of 12,680,148 shares in the last 24 months. This volume of shares sold represents approximately $20.44M in transactions. Related Companies BioCryst Pharmaceuticals Major Shareholders Celldex Therapeutics Major Shareholders Novavax Major Shareholders Innoviva Major Shareholders MannKind Major Shareholders Dynavax Technologies Major Shareholders OPKO Health Major Shareholders Geron Major Shareholders Rigel Pharmaceuticals Major Shareholders Zenas BioPharma Major Shareholders This page (NASDAQ:RGLS) was last updated on 9/2/2025 by MarketBeat.com Staff From Our PartnersMan Who Called Nvidia at $1.10 Says Buy This Now...In 2004, one man called Nvidia before just about anyone knew it existed. Now, this same guy says a new comp...The Oxford Club | SponsoredGoogle did what!?!?A new technology has sparked a modern-day gold rush in Silicon Valley. OpenAI’s Sam Altman invested $375M. 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