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OPKO Health (OPK) Institutional Ownership

OPKO Health logo
$1.38 +0.01 (+0.73%)
Closing price 10/9/2026 04:00 PM Eastern
Extended Trading
$1.36 -0.01 (-1.09%)
As of 10/9/2026 07:49 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Institutional Ownership Changes (13F Filings) for OPKO Health (NASDAQ:OPK)

Current
Institutional Ownership
Percentage
64.63%
Number of
Institutional Buyers
(last 12 months)
69
Total
Institutional Inflows
(last 12 months)
$79.84M
Number of
Institutional Sellers
(last 12 months)
41
Total
Institutional Outflows
(last 12 months)
$9.86M
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OPK Institutional Buying and Selling by Quarter

OPKO Health Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
9/9/2026Squarepoint Ops LLC41,591$62K0.0%N/A0.006%
9/8/2026Arizona State Retirement System104,725$157K0.0%-9.7%0.014%
8/20/2026Headlands Technologies LLC107,989$162K0.0%+91.2%0.014%
8/20/2026Two Sigma Securities LLC18,270$27K0.0%N/A0.002%
8/19/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC574,107$861K0.0%-14.9%0.077%
8/19/2026Van ECK Associates Corp438,645$658K0.0%+174.0%0.059%
8/19/2026Hsbc Holdings PLC199,966$299K0.0%-16.1%0.027%
8/17/2026Bank of America Corp DE795,716$1.19M0.0%N/A0.107%
8/15/2026Jupiter Topco LLC206,314$311K0.0%N/A0.028%
8/15/2026AWM Investment Company Inc.2,110,000$3.17M0.3%N/A0.283%
8/14/2026Hsbc Holdings PLC199,966$299K0.0%N/A0.027%
8/14/2026Legal & General Group Plc346,787$520K0.0%N/A0.046%
8/14/2026The Manufacturers Life Insurance Company119,132$179K0.0%N/A0.016%
8/14/2026Algert Global LLC397,030$596K0.0%N/A0.053%
8/13/2026Connor Clark & Lunn Investment Management Ltd.412,051$618K0.0%N/A0.055%
8/12/2026EP Wealth Advisors LLC29,722$45K0.0%N/A0.004%
8/12/2026Ieq Capital LLC169,425$254K0.0%N/A0.023%
8/10/2026Diversify Advisory Services LLC30,000$37K0.0%N/A0.004%
8/7/2026BlackRock Inc.36,978,893$55.47M0.0%N/A4.955%
8/7/2026Deutsche Bank AG398,603$598K0.0%N/A0.053%
8/6/2026Bank of New York Mellon Corp1,329,974$2.00M0.0%N/A0.178%
8/6/2026State of Wyoming116,489$175K0.0%N/A0.016%
7/9/2026Allied Private Wealth LLC91,137$129K0.1%N/A0.012%
7/8/2026Assenagon Asset Management S.A.285,339$426K0.0%-56.2%0.038%
5/22/2026Wellington Grp LLC30,000$34K0.0%-50.0%0.004%
5/19/2026Bank of America Corp DE1,141,849$1.30M0.0%+80.0%0.151%
5/18/2026Royal Bank of Canada219,994$251K0.0%-15.7%0.029%
5/16/2026The Manufacturers Life Insurance Company122,128$139K0.0%-46.8%0.016%
5/14/2026Renaissance Technologies LLC109,543$125K0.0%N/A0.015%
5/14/2026State of Wyoming167,020$190K0.0%N/A0.022%
5/13/2026First Trust Advisors LP500,273$570K0.0%N/A0.066%
5/7/2026Dimensional Fund Advisors LP1,560,000$1.78M0.0%-3.2%0.207%
5/5/2026Bank of New York Mellon Corp1,280,042$1.46M0.0%-2.3%0.170%
5/1/2026Fifth Third Bancorp128,791$147K0.0%N/A0.017%
4/30/2026Hsbc Holdings PLC238,281$273K0.0%N/A0.032%
4/28/2026Abel Hall LLC33,271$38K0.0%N/A0.004%
4/27/2026PFG Investments LLC1,112,776$1.27M0.1%-15.7%0.147%
4/20/2026OP Asset Management Ltd1,102,254$1.26M0.0%N/A0.145%
4/20/2026Apella Capital LLC27,021$34K0.0%N/A0.004%
4/16/2026SG Americas Securities LLC87,846$100K0.0%+62.6%0.012%
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3/13/2026World Investment Advisors66,520$84K0.0%+63.8%0.009%
3/3/2026Caitong International Asset Management Co. Ltd39,232$49K0.0%+1,056.9%0.005%
2/23/2026Virtu Financial LLC115,298$145K0.0%N/A0.015%
2/19/2026Invesco Ltd.781,672$985K0.0%-23.2%0.102%
2/18/2026Mercer Global Advisors Inc. ADV59,026$74K0.0%-24.2%0.008%
2/18/2026EP Wealth Advisors LLC29,446$37K0.0%N/A0.004%
2/18/2026XTX Topco Ltd342,757$432K0.0%N/A0.045%
2/18/2026Zacks Investment Management21,322$27K0.0%N/A0.003%
2/18/2026Quadrature Capital Ltd91,702$116K0.0%N/A0.012%
2/18/2026Millennium Management LLC265,268$334K0.0%N/A0.035%
2/18/2026Balyasny Asset Management L.P.198,821$251K0.0%N/A0.026%
2/17/2026AQR Capital Management LLC2,026,957$2.55M0.0%-29.5%0.264%
2/17/2026SIH Partners LLLP104,334$131K0.0%-30.5%0.014%
2/17/2026Price T Rowe Associates Inc. MD367,191$463K0.0%+7.0%0.048%
2/17/2026Atom Investors LP28,258$36K0.0%-32.5%0.004%
2/17/2026State of Wisconsin Investment Board26,437$33K0.0%-32.4%0.003%
2/17/2026Captrust Financial Advisors40,120$51K0.0%-41.0%0.005%
2/17/2026Royal Bank of Canada261,020$329K0.0%-4.3%0.034%
2/17/2026Graham Capital Management L.P.119,654$151K0.0%+21.6%0.016%
2/16/2026Verition Fund Management LLC50,650$64K0.0%-36.3%0.007%
2/16/2026Mariner LLC42,225$53K0.0%-38.8%0.006%
2/16/2026Barclays PLC663,236$836K0.0%+12.8%0.086%
2/13/2026AWM Investment Company Inc.2,100,000$2.65M0.3%-4.5%0.274%
2/13/2026Headlands Technologies LLC88,962$112K0.0%+96.6%0.012%
2/13/2026Charles Schwab Investment Management Inc.3,692,650$4.65M0.0%-2.0%0.481%
2/13/2026State Street Corp8,951,762$11.28M0.0%-0.5%1.166%
2/13/2026Van ECK Associates Corp137,019$173K0.0%+22.5%0.018%
2/13/2026Ieq Capital LLC157,779$199K0.0%-43.2%0.021%
2/13/2026Wells Fargo & Company MN468,518$590K0.0%+36.8%0.061%
2/12/2026Hollencrest Capital Management40,000$50K0.0%-55.6%0.005%
2/12/2026HRT Financial LP675,483$851K0.0%N/A0.088%
2/12/2026MetLife Investment Management LLC175,676$221K0.0%-15.2%0.023%
2/12/2026Cibc World Markets Corp27,225$34K0.0%N/A0.004%
2/12/2026Commonwealth Equity Services LLC641,456$808K0.0%+8.3%0.084%
2/12/2026StoneX Group Inc.21,599$27K0.0%N/A0.003%
2/12/2026Dimensional Fund Advisors LP1,611,318$2.03M0.0%-3.4%0.210%
2/12/2026EntryPoint Capital LLC309,024$389K0.2%+695.9%0.040%
2/12/2026New York State Common Retirement Fund114,301$144K0.0%-12.7%0.015%
2/11/2026Deutsche Bank AG325,889$411K0.0%+18.4%0.042%
2/11/2026LPL Financial LLC22,458$28K0.0%-27.4%0.003%
2/10/2026Goldman Sachs Group Inc.5,986,913$7.54M0.0%+150.9%0.780%
2/10/2026Intech Investment Management LLC159,652$201K0.0%+11.4%0.021%
2/9/2026Geode Capital Management LLC11,061,318$13.94M0.0%+0.6%1.441%
2/6/2026PNC Financial Services Group Inc.37,000$47K0.0%-35.1%0.005%
2/6/2026ProShare Advisors LLC156,354$197K0.0%+122.2%0.020%
2/4/2026World Investment Advisors66,520$84K0.0%+63.8%0.009%
1/29/2026Comerica Bank120,000$151K0.0%+7.1%0.016%
1/29/2026UBS Group AG5,352,784$6.75M0.0%+12.1%0.697%
1/28/2026Arizona State Retirement System113,834$143K0.0%-11.5%0.015%
1/26/2026CWM LLC69,147$87K0.0%-44.6%0.009%
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1/26/2026PFG Investments LLC1,320,391$1.66M0.1%-1.3%0.172%
1/21/2026Y.D. More Investments Ltd1,306,452$1.67M0.1%-12.9%0.170%
1/9/2026SG Americas Securities LLC54,022$68K0.0%-37.9%0.007%
1/9/2026Assenagon Asset Management S.A.652,066$835K0.0%-5.5%0.085%
1/8/2026Wealth Enhancement Advisory Services LLC57,529$76K0.0%-24.1%0.007%
12/2/2025Swiss Life Asset Management Ltd19,164$30K0.0%N/A0.002%
11/21/2025CIBC Bancorp USA Inc.43,868$68K0.0%N/A0.006%
11/18/2025Cim Investment Management Inc.25,804$40K0.0%-51.9%0.003%
11/17/2025Verition Fund Management LLC79,534$123K0.0%+57.0%0.010%
11/17/2025SIH Partners LLLP150,125$233K0.0%+116.3%0.020%


OPK Institutional Ownership - Frequently Asked Questions

During the previous two years, 158 institutional investors and hedge funds held shares of OPKO Health. The most heavily invested institutionals were Rubric Capital Management LP ($72.57M), Vanguard Group Inc. ($58.18M), BlackRock Inc. ($55.47M), Sculptor Capital LP ($21.11M), Geode Capital Management LLC ($13.94M), State Street Corp ($11.28M), and Goldman Sachs Group Inc. ($7.54M).Learn more on OPKO Health's institutional investors.

64.63% of OPKO Health's stock is owned by institutional investors. Learn more on OPK's institutional investor holdings.

Of the 129 institutional investors that purchased OPKO Health's stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: BlackRock Inc. ($36.98M), Sculptor Capital LP ($12.72M), Rubric Capital Management LP ($4.28M), Millennium Management LLC ($4.18M), Goldman Sachs Group Inc. ($3.92M), Graham Capital Management L.P. ($3.41M), and AWM Investment Company Inc. ($2.81M).

Institutional investors have bought a total of 54,982,729 shares in the last 24 months. This purchase volume represents approximately $79.84M in transactions.

Of the 41 institutional investors that sold OPKO Health's stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: UBS Group AG ($944.10K), AQR Capital Management LLC ($846.46K), Vanguard Group Inc. ($702.82K), Two Sigma Investments LP ($581.10K), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($554.65K), BNP Paribas Financial Markets ($463.36K), and Assenagon Asset Management S.A. ($404.86K).

Institutional investors have sold a total of 6,909,189 shares in the last 24 months. This volume of shares sold represents approximately $9.86M in transactions.


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Institutional ownership data for NASDAQ:OPK is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 9/9/2026. New 13F filings are added each quarter as they're published.
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