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OPKO Health (OPK) Institutional Ownership

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$1.67 +0.05 (+3.09%)
Closing price 09/18/2026 04:00 PM Eastern
Extended Trading
$1.59 -0.08 (-4.67%)
As of 09/18/2026 07:37 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Institutional Ownership Changes (13F Filings) for OPKO Health (NASDAQ:OPK)

Current
Institutional Ownership
Percentage
64.63%
Number of
Institutional Buyers
(last 12 months)
69
Total
Institutional Inflows
(last 12 months)
$79.84M
Number of
Institutional Sellers
(last 12 months)
42
Total
Institutional Outflows
(last 12 months)
$10.40M
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OPK Institutional Buying and Selling by Quarter

OPKO Health Major Shareholders & Ownership History

Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
9/9/2026 Squarepoint Ops LLC41,591$62K0.0%N/A0.006%
9/8/2026 Arizona State Retirement System104,725$157K0.0%-9.7%0.014%
8/20/2026 Headlands Technologies LLC107,989$162K0.0%+91.2%0.014%
8/20/2026 Two Sigma Securities LLC18,270$27K0.0%N/A0.002%
8/19/2026 UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC574,107$861K0.0%-14.9%0.077%
8/19/2026 Van ECK Associates Corp438,645$658K0.0%+174.0%0.059%
8/19/2026 Hsbc Holdings PLC199,966$299K0.0%-16.1%0.027%
8/17/2026 Bank of America Corp DE795,716$1.19M0.0%N/A0.107%
8/15/2026 Jupiter Topco LLC206,314$311K0.0%N/A0.028%
8/15/2026 AWM Investment Company Inc.2,110,000$3.17M0.3%N/A0.283%
8/14/2026 Hsbc Holdings PLC199,966$299K0.0%N/A0.027%
8/14/2026 Legal & General Group Plc346,787$520K0.0%N/A0.046%
8/14/2026 The Manufacturers Life Insurance Company119,132$179K0.0%N/A0.016%
8/14/2026 Algert Global LLC397,030$596K0.0%N/A0.053%
8/13/2026 Connor Clark & Lunn Investment Management Ltd.412,051$618K0.0%N/A0.055%
8/12/2026 EP Wealth Advisors LLC29,722$45K0.0%N/A0.004%
8/12/2026 Ieq Capital LLC169,425$254K0.0%N/A0.023%
8/10/2026 Diversify Advisory Services LLC30,000$37K0.0%N/A0.004%
8/7/2026 BlackRock Inc.36,978,893$55.47M0.0%N/A4.955%
8/7/2026 Deutsche Bank AG398,603$598K0.0%N/A0.053%
8/6/2026 Bank of New York Mellon Corp1,329,974$2.00M0.0%N/A0.178%
8/6/2026 State of Wyoming116,489$175K0.0%N/A0.016%
7/9/2026 Allied Private Wealth LLC91,137$129K0.1%N/A0.012%
7/8/2026 Assenagon Asset Management S.A.285,339$426K0.0%-56.2%0.038%
5/22/2026 Wellington Grp LLC30,000$34K0.0%-50.0%0.004%
5/19/2026 Bank of America Corp DE1,141,849$1.30M0.0%+80.0%0.151%
5/18/2026 Royal Bank of Canada219,994$251K0.0%-15.7%0.029%
5/16/2026 The Manufacturers Life Insurance Company122,128$139K0.0%-46.8%0.016%
5/14/2026 Renaissance Technologies LLC109,543$125K0.0%N/A0.015%
5/14/2026 State of Wyoming167,020$190K0.0%N/A0.022%
5/13/2026 First Trust Advisors LP500,273$570K0.0%N/A0.066%
5/7/2026 Dimensional Fund Advisors LP1,560,000$1.78M0.0%-3.2%0.207%
5/5/2026 Bank of New York Mellon Corp1,280,042$1.46M0.0%-2.3%0.170%
5/1/2026 Fifth Third Bancorp128,791$147K0.0%N/A0.017%
4/30/2026 Hsbc Holdings PLC238,281$273K0.0%N/A0.032%
4/28/2026 Abel Hall LLC33,271$38K0.0%N/A0.004%
4/27/2026 PFG Investments LLC1,112,776$1.27M0.1%-15.7%0.147%
4/20/2026 OP Asset Management Ltd1,102,254$1.26M0.0%N/A0.145%
4/20/2026 Apella Capital LLC27,021$34K0.0%N/A0.004%
4/16/2026 SG Americas Securities LLC87,846$100K0.0%+62.6%0.012%
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3/13/2026 World Investment Advisors66,520$84K0.0%+63.8%0.009%
3/3/2026 Caitong International Asset Management Co. Ltd39,232$49K0.0%+1,056.9%0.005%
2/23/2026 Virtu Financial LLC115,298$145K0.0%N/A0.015%
2/19/2026 Invesco Ltd.781,672$985K0.0%-23.2%0.102%
2/18/2026 Mercer Global Advisors Inc. ADV59,026$74K0.0%-24.2%0.008%
2/18/2026 EP Wealth Advisors LLC29,446$37K0.0%N/A0.004%
2/18/2026 XTX Topco Ltd342,757$432K0.0%N/A0.045%
2/18/2026 Zacks Investment Management21,322$27K0.0%N/A0.003%
2/18/2026 Quadrature Capital Ltd91,702$116K0.0%N/A0.012%
2/18/2026 Millennium Management LLC265,268$334K0.0%N/A0.035%
2/18/2026 Balyasny Asset Management L.P.198,821$251K0.0%N/A0.026%
2/17/2026 AQR Capital Management LLC2,026,957$2.55M0.0%-29.5%0.264%
2/17/2026 SIH Partners LLLP104,334$131K0.0%-30.5%0.014%
2/17/2026 Price T Rowe Associates Inc. MD367,191$463K0.0%+7.0%0.048%
2/17/2026 Atom Investors LP28,258$36K0.0%-32.5%0.004%
2/17/2026 State of Wisconsin Investment Board26,437$33K0.0%-32.4%0.003%
2/17/2026 Captrust Financial Advisors40,120$51K0.0%-41.0%0.005%
2/17/2026 Royal Bank of Canada261,020$329K0.0%-4.3%0.034%
2/17/2026 Graham Capital Management L.P.119,654$151K0.0%+21.6%0.016%
2/16/2026 Verition Fund Management LLC50,650$64K0.0%-36.3%0.007%
2/16/2026 Mariner LLC42,225$53K0.0%-38.8%0.006%
2/16/2026 Barclays PLC663,236$836K0.0%+12.8%0.086%
2/13/2026 AWM Investment Company Inc.2,100,000$2.65M0.3%-4.5%0.274%
2/13/2026 Headlands Technologies LLC88,962$112K0.0%+96.6%0.012%
2/13/2026 Charles Schwab Investment Management Inc.3,692,650$4.65M0.0%-2.0%0.481%
2/13/2026 State Street Corp8,951,762$11.28M0.0%-0.5%1.166%
2/13/2026 Van ECK Associates Corp137,019$173K0.0%+22.5%0.018%
2/13/2026 Ieq Capital LLC157,779$199K0.0%-43.2%0.021%
2/13/2026 Wells Fargo & Company MN468,518$590K0.0%+36.8%0.061%
2/12/2026 Hollencrest Capital Management40,000$50K0.0%-55.6%0.005%
2/12/2026 HRT Financial LP675,483$851K0.0%N/A0.088%
2/12/2026 MetLife Investment Management LLC175,676$221K0.0%-15.2%0.023%
2/12/2026Cibc World Markets Corp27,225$34K0.0%N/A0.004%
2/12/2026 Commonwealth Equity Services LLC641,456$808K0.0%+8.3%0.084%
2/12/2026 StoneX Group Inc.21,599$27K0.0%N/A0.003%
2/12/2026 Dimensional Fund Advisors LP1,611,318$2.03M0.0%-3.4%0.210%
2/12/2026 EntryPoint Capital LLC309,024$389K0.2%+695.9%0.040%
2/12/2026 New York State Common Retirement Fund114,301$144K0.0%-12.7%0.015%
2/11/2026 Deutsche Bank AG325,889$411K0.0%+18.4%0.042%
2/11/2026 LPL Financial LLC22,458$28K0.0%-27.4%0.003%
2/10/2026 Goldman Sachs Group Inc.5,986,913$7.54M0.0%+150.9%0.780%
2/10/2026 Intech Investment Management LLC159,652$201K0.0%+11.4%0.021%
2/9/2026 Geode Capital Management LLC11,061,318$13.94M0.0%+0.6%1.441%
2/6/2026 PNC Financial Services Group Inc.37,000$47K0.0%-35.1%0.005%
2/6/2026 ProShare Advisors LLC156,354$197K0.0%+122.2%0.020%
2/4/2026 World Investment Advisors66,520$84K0.0%+63.8%0.009%
1/29/2026Comerica Bank120,000$151K0.0%+7.1%0.016%
1/29/2026 UBS Group AG5,352,784$6.75M0.0%+12.1%0.697%
1/28/2026 Arizona State Retirement System113,834$143K0.0%-11.5%0.015%
1/26/2026CWM LLC69,147$87K0.0%-44.6%0.009%
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1/26/2026 PFG Investments LLC1,320,391$1.66M0.1%-1.3%0.172%
1/21/2026 Y.D. More Investments Ltd1,306,452$1.67M0.1%-12.9%0.170%
1/9/2026 SG Americas Securities LLC54,022$68K0.0%-37.9%0.007%
1/9/2026 Assenagon Asset Management S.A.652,066$835K0.0%-5.5%0.085%
1/8/2026 Wealth Enhancement Advisory Services LLC57,529$76K0.0%-24.1%0.007%
12/2/2025 Swiss Life Asset Management Ltd19,164$30K0.0%N/A0.002%
11/21/2025 CIBC Bancorp USA Inc.43,868$68K0.0%N/A0.006%
11/18/2025Cim Investment Management Inc.25,804$40K0.0%-51.9%0.003%
11/17/2025 Verition Fund Management LLC79,534$123K0.0%+57.0%0.010%
11/17/2025 SIH Partners LLLP150,125$233K0.0%+116.3%0.020%


OPK Institutional Ownership - Frequently Asked Questions

During the previous two years, 158 institutional investors and hedge funds held shares of OPKO Health. The most heavily invested institutionals were Rubric Capital Management LP ($72.57M), Vanguard Group Inc. ($58.18M), BlackRock Inc. ($55.47M), Sculptor Capital LP ($21.11M), Geode Capital Management LLC ($13.94M), State Street Corp ($11.28M), and Goldman Sachs Group Inc. ($7.54M).Learn more on OPKO Health's institutional investors.

64.63% of OPKO Health's stock is owned by institutional investors. Learn more on OPK's institutional investor holdings.

Of the 130 institutional investors that purchased OPKO Health's stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: BlackRock Inc. ($36.98M), Sculptor Capital LP ($12.72M), Rubric Capital Management LP ($4.28M), Millennium Management LLC ($4.18M), Goldman Sachs Group Inc. ($3.92M), Graham Capital Management L.P. ($3.41M), and AWM Investment Company Inc. ($2.81M).

Institutional investors have bought a total of 54,982,729 shares in the last 24 months. This purchase volume represents approximately $79.84M in transactions.

Of the 42 institutional investors that sold OPKO Health's stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: UBS Group AG ($944.10K), AQR Capital Management LLC ($846.46K), Vanguard Group Inc. ($702.82K), Assenagon Asset Management S.A. ($649.76K), Two Sigma Investments LP ($581.10K), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($554.65K), and BNP Paribas Financial Markets ($463.36K).

Institutional investors have sold a total of 7,255,648 shares in the last 24 months. This volume of shares sold represents approximately $10.40M in transactions.



Institutional ownership data for NASDAQ:OPK is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 9/9/2026. New 13F filings are added each quarter as they're published.
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