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OPKO Health (OPK) Competitors

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$1.31 0.00 (0.00%)
Closing price 04:00 PM Eastern
Extended Trading
$1.33 +0.02 (+1.53%)
As of 04:35 PM Eastern
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OPK vs. CLDX, BCRX, ZBIO, INVA, and MNKD

Should you buy OPKO Health stock or one of its competitors? MarketBeat compares OPKO Health with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with OPKO Health include Celldex Therapeutics (CLDX), BioCryst Pharmaceuticals (BCRX), Zenas BioPharma (ZBIO), Innoviva (INVA), and MannKind (MNKD).

How does OPKO Health compare to Celldex Therapeutics?

Celldex Therapeutics (NASDAQ:CLDX) and OPKO Health (NASDAQ:OPK) are both healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their dividends, valuation, analyst recommendations, media sentiment, institutional ownership, risk, profitability and earnings.

Celldex Therapeutics currently has a consensus price target of $54.62, indicating a potential upside of 39.31%. OPKO Health has a consensus price target of $1.55, indicating a potential upside of 16.98%. Given Celldex Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Celldex Therapeutics is more favorable than OPKO Health.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Celldex Therapeutics
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.86
OPKO Health
1 Sell rating(s)
4 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

OPKO Health has higher revenue and earnings than Celldex Therapeutics. OPKO Health is trading at a lower price-to-earnings ratio than Celldex Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Celldex Therapeutics$1.54M1,998.18-$258.76M-$4.26N/A
OPKO Health$606.90M1.63-$225.68M-$0.09N/A

In the previous week, OPKO Health had 6 more articles in the media than Celldex Therapeutics. MarketBeat recorded 15 mentions for OPKO Health and 9 mentions for Celldex Therapeutics. Celldex Therapeutics' average media sentiment score of 1.15 beat OPKO Health's score of 0.43 indicating that Celldex Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Celldex Therapeutics
5 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
OPKO Health
3 Very Positive mention(s)
3 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

64.6% of OPKO Health shares are owned by institutional investors. 5.2% of Celldex Therapeutics shares are owned by insiders. Comparatively, 44.7% of OPKO Health shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Celldex Therapeutics has a beta of 0.87, indicating that its stock price is 13% less volatile than the broader market. Comparatively, OPKO Health has a beta of 1.51, indicating that its stock price is 51% more volatile than the broader market.

Celldex Therapeutics has a net margin of 0.00% compared to OPKO Health's net margin of -12.40%. OPKO Health's return on equity of -5.88% beat Celldex Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Celldex TherapeuticsN/A -50.72% -46.59%
OPKO Health -12.40%-5.88%-3.83%

Summary

OPKO Health beats Celldex Therapeutics on 9 of the 17 factors compared between the two stocks.

How does OPKO Health compare to BioCryst Pharmaceuticals?

OPKO Health (NASDAQ:OPK) and BioCryst Pharmaceuticals (NASDAQ:BCRX) are both healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their dividends, media sentiment, risk, institutional ownership, earnings, analyst recommendations, profitability and valuation.

In the previous week, OPKO Health had 7 more articles in the media than BioCryst Pharmaceuticals. MarketBeat recorded 15 mentions for OPKO Health and 8 mentions for BioCryst Pharmaceuticals. BioCryst Pharmaceuticals' average media sentiment score of 1.33 beat OPKO Health's score of 0.43 indicating that BioCryst Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
OPKO Health
3 Very Positive mention(s)
3 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
BioCryst Pharmaceuticals
6 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

OPKO Health has a beta of 1.51, indicating that its stock price is 51% more volatile than the broader market. Comparatively, BioCryst Pharmaceuticals has a beta of 0.56, indicating that its stock price is 44% less volatile than the broader market.

BioCryst Pharmaceuticals has higher revenue and earnings than OPKO Health. OPKO Health is trading at a lower price-to-earnings ratio than BioCryst Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
OPKO Health$606.90M1.63-$225.68M-$0.09N/A
BioCryst Pharmaceuticals$874.84M2.59$263.86M-$1.78N/A

OPKO Health currently has a consensus price target of $1.55, indicating a potential upside of 16.98%. BioCryst Pharmaceuticals has a consensus price target of $20.80, indicating a potential upside of 133.05%. Given BioCryst Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe BioCryst Pharmaceuticals is more favorable than OPKO Health.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
OPKO Health
1 Sell rating(s)
4 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
BioCryst Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.67

OPKO Health has a net margin of -12.40% compared to BioCryst Pharmaceuticals' net margin of -51.71%. OPKO Health's return on equity of -5.88% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
OPKO Health-12.40% -5.88% -3.83%
BioCryst Pharmaceuticals -51.71%-76.36%60.12%

64.6% of OPKO Health shares are owned by institutional investors. Comparatively, 85.9% of BioCryst Pharmaceuticals shares are owned by institutional investors. 44.7% of OPKO Health shares are owned by insiders. Comparatively, 3.8% of BioCryst Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Summary

BioCryst Pharmaceuticals beats OPKO Health on 10 of the 16 factors compared between the two stocks.

How does OPKO Health compare to Zenas BioPharma?

Zenas BioPharma (NASDAQ:ZBIO) and OPKO Health (NASDAQ:OPK) are both small-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their dividends, media sentiment, institutional ownership, risk, earnings, profitability, analyst recommendations and valuation.

Zenas BioPharma has a beta of -1.03, suggesting that its share price is 203% less volatile than the broader market. Comparatively, OPKO Health has a beta of 1.51, suggesting that its share price is 51% more volatile than the broader market.

In the previous week, OPKO Health had 11 more articles in the media than Zenas BioPharma. MarketBeat recorded 15 mentions for OPKO Health and 4 mentions for Zenas BioPharma. Zenas BioPharma's average media sentiment score of 0.64 beat OPKO Health's score of 0.43 indicating that Zenas BioPharma is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zenas BioPharma
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
OPKO Health
3 Very Positive mention(s)
3 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Zenas BioPharma presently has a consensus price target of $44.29, indicating a potential upside of 41.31%. OPKO Health has a consensus price target of $1.55, indicating a potential upside of 16.98%. Given Zenas BioPharma's stronger consensus rating and higher possible upside, research analysts plainly believe Zenas BioPharma is more favorable than OPKO Health.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zenas BioPharma
1 Sell rating(s)
2 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.56
OPKO Health
1 Sell rating(s)
4 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

OPKO Health has higher revenue and earnings than Zenas BioPharma. OPKO Health is trading at a lower price-to-earnings ratio than Zenas BioPharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zenas BioPharma$10M197.85-$377.74M-$8.47N/A
OPKO Health$606.90M1.63-$225.68M-$0.09N/A

Zenas BioPharma has a net margin of 0.00% compared to OPKO Health's net margin of -12.40%. OPKO Health's return on equity of -5.88% beat Zenas BioPharma's return on equity.

Company Net Margins Return on Equity Return on Assets
Zenas BioPharmaN/A -99.99% -58.06%
OPKO Health -12.40%-5.88%-3.83%

64.6% of OPKO Health shares are owned by institutional investors. 22.0% of Zenas BioPharma shares are owned by insiders. Comparatively, 44.7% of OPKO Health shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Summary

OPKO Health beats Zenas BioPharma on 9 of the 16 factors compared between the two stocks.

How does OPKO Health compare to Innoviva?

Innoviva (NASDAQ:INVA) and OPKO Health (NASDAQ:OPK) are both small-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their risk, valuation, analyst recommendations, dividends, institutional ownership, profitability, media sentiment and earnings.

Innoviva presently has a consensus target price of $36.20, indicating a potential upside of 73.56%. OPKO Health has a consensus target price of $1.55, indicating a potential upside of 16.98%. Given Innoviva's stronger consensus rating and higher possible upside, equities research analysts plainly believe Innoviva is more favorable than OPKO Health.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Innoviva
2 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.43
OPKO Health
1 Sell rating(s)
4 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

99.1% of Innoviva shares are owned by institutional investors. Comparatively, 64.6% of OPKO Health shares are owned by institutional investors. 2.0% of Innoviva shares are owned by company insiders. Comparatively, 44.7% of OPKO Health shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Innoviva has higher earnings, but lower revenue than OPKO Health. OPKO Health is trading at a lower price-to-earnings ratio than Innoviva, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Innoviva$411.33M3.74$271.17M$6.013.47
OPKO Health$606.90M1.63-$225.68M-$0.09N/A

Innoviva has a net margin of 119.89% compared to OPKO Health's net margin of -12.40%. Innoviva's return on equity of 33.33% beat OPKO Health's return on equity.

Company Net Margins Return on Equity Return on Assets
Innoviva119.89% 33.33% 22.67%
OPKO Health -12.40%-5.88%-3.83%

In the previous week, OPKO Health had 6 more articles in the media than Innoviva. MarketBeat recorded 15 mentions for OPKO Health and 9 mentions for Innoviva. Innoviva's average media sentiment score of 0.96 beat OPKO Health's score of 0.43 indicating that Innoviva is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Innoviva
5 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive
OPKO Health
3 Very Positive mention(s)
3 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral

Innoviva has a beta of 0.35, suggesting that its share price is 65% less volatile than the broader market. Comparatively, OPKO Health has a beta of 1.51, suggesting that its share price is 51% more volatile than the broader market.

Summary

Innoviva beats OPKO Health on 12 of the 16 factors compared between the two stocks.

How does OPKO Health compare to MannKind?

OPKO Health (NASDAQ:OPK) and MannKind (NASDAQ:MNKD) are both small-cap healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their media sentiment, dividends, institutional ownership, profitability, risk, earnings, analyst recommendations and valuation.

MannKind has a net margin of -6.63% compared to OPKO Health's net margin of -12.40%. OPKO Health's return on equity of -5.88% beat MannKind's return on equity.

Company Net Margins Return on Equity Return on Assets
OPKO Health-12.40% -5.88% -3.83%
MannKind -6.63%-11.21%-3.92%

64.6% of OPKO Health shares are owned by institutional investors. Comparatively, 49.6% of MannKind shares are owned by institutional investors. 44.7% of OPKO Health shares are owned by company insiders. Comparatively, 2.6% of MannKind shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

OPKO Health has a beta of 1.51, suggesting that its share price is 51% more volatile than the broader market. Comparatively, MannKind has a beta of 1.12, suggesting that its share price is 12% more volatile than the broader market.

OPKO Health currently has a consensus target price of $1.55, indicating a potential upside of 16.98%. MannKind has a consensus target price of $9.34, indicating a potential upside of 136.85%. Given MannKind's stronger consensus rating and higher probable upside, analysts plainly believe MannKind is more favorable than OPKO Health.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
OPKO Health
1 Sell rating(s)
4 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
MannKind
2 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.50

MannKind has lower revenue, but higher earnings than OPKO Health. MannKind is trading at a lower price-to-earnings ratio than OPKO Health, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
OPKO Health$606.90M1.63-$225.68M-$0.09N/A
MannKind$348.97M3.49$5.86M-$0.07N/A

In the previous week, OPKO Health had 3 more articles in the media than MannKind. MarketBeat recorded 15 mentions for OPKO Health and 12 mentions for MannKind. MannKind's average media sentiment score of 0.88 beat OPKO Health's score of 0.43 indicating that MannKind is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
OPKO Health
3 Very Positive mention(s)
3 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
MannKind
5 Very Positive mention(s)
3 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

OPKO Health and MannKind tied by winning 8 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding OPK and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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OPK vs. The Competition

MetricOPKO HealthHealthcare Providers & Services IndustryHealthcare SectorNASDAQ Exchange
Market Cap$988.89M$9.87B$6.79B$13.03B
Dividend YieldN/A2.54%2.60%10.03%
P/E Ratio-14.7225.68279.7125.52
Price / Sales1.634.84649.11116.03
Price / CashN/A26.4428.6434.82
Price / Book0.795.2011.166.36
Net Income-$225.68M$312.25M$3.48B$347.60M
7 Day Performance-20.30%-0.87%2.55%3.18%
1 Month Performance-13.49%-0.89%-2.76%-2.03%
1 Year Performance3.54%24.91%64.39%21.31%

OPKO Health Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
OPK
OPKO Health
1.6176 of 5 stars
$1.31
flat
$1.55
+18.3%
+10.1%$977.69M$606.90MN/A1,373
CLDX
Celldex Therapeutics
2.9965 of 5 stars
$35.65
+1.0%
$52.77
+48.0%
+69.9%$2.77B$1.54MN/A150
BCRX
BioCryst Pharmaceuticals
3.8193 of 5 stars
$9.58
+2.6%
$20.80
+117.1%
+10.8%$2.37B$874.84MN/A530
ZBIO
Zenas BioPharma
3.4804 of 5 stars
$32.82
+8.0%
$44.29
+34.9%
+102.0%$1.92B$10MN/AN/A
INVA
Innoviva
3.2116 of 5 stars
$21.30
-0.7%
$36.20
+70.0%
+11.5%$1.58B$411.33M3.54100

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This page (NASDAQ:OPK) was last updated on 8/4/2026 by MarketBeat.com Staff.
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