OPKO Health (OPK) Competitors $1.26 -0.04 (-3.08%) As of 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock OPK vs. BCRX, LGND, FOLD, MNKD, DVAX, CLDX, INVA, NVAX, GERN, and MYGNShould you be buying OPKO Health stock or one of its competitors? The main competitors of OPKO Health include BioCryst Pharmaceuticals (BCRX), Ligand Pharmaceuticals (LGND), Amicus Therapeutics (FOLD), MannKind (MNKD), Dynavax Technologies (DVAX), Celldex Therapeutics (CLDX), Innoviva (INVA), Novavax (NVAX), Geron (GERN), and Myriad Genetics (MYGN). These companies are all part of the "biotechnology" industry. OPKO Health vs. BioCryst Pharmaceuticals Ligand Pharmaceuticals Amicus Therapeutics MannKind Dynavax Technologies Celldex Therapeutics Innoviva Novavax Geron Myriad Genetics OPKO Health (NASDAQ:OPK) and BioCryst Pharmaceuticals (NASDAQ:BCRX) are both medical companies, but which is the superior business? We will compare the two businesses based on the strength of their media sentiment, community ranking, institutional ownership, analyst recommendations, dividends, profitability, valuation, risk and earnings. Do analysts recommend OPK or BCRX? OPKO Health currently has a consensus price target of $2.75, indicating a potential upside of 112.36%. BioCryst Pharmaceuticals has a consensus price target of $16.56, indicating a potential upside of 68.76%. Given OPKO Health's higher probable upside, analysts plainly believe OPKO Health is more favorable than BioCryst Pharmaceuticals.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score OPKO Health 0 Sell rating(s) 1 Hold rating(s) 3 Buy rating(s) 0 Strong Buy rating(s) 2.75BioCryst Pharmaceuticals 0 Sell rating(s) 1 Hold rating(s) 8 Buy rating(s) 0 Strong Buy rating(s) 2.89 Do institutionals & insiders believe in OPK or BCRX? 64.6% of OPKO Health shares are owned by institutional investors. Comparatively, 85.9% of BioCryst Pharmaceuticals shares are owned by institutional investors. 49.7% of OPKO Health shares are owned by insiders. Comparatively, 4.8% of BioCryst Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth. Which has more volatility & risk, OPK or BCRX? OPKO Health has a beta of 1.42, indicating that its share price is 42% more volatile than the S&P 500. Comparatively, BioCryst Pharmaceuticals has a beta of 1.08, indicating that its share price is 8% more volatile than the S&P 500. Which has preferable earnings and valuation, OPK or BCRX? OPKO Health has higher revenue and earnings than BioCryst Pharmaceuticals. BioCryst Pharmaceuticals is trading at a lower price-to-earnings ratio than OPKO Health, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioOPKO Health$689.41M1.49-$188.86M-$0.07-18.50BioCryst Pharmaceuticals$503.49M4.08-$226.54M-$0.26-37.73 Does the MarketBeat Community prefer OPK or BCRX? OPKO Health received 16 more outperform votes than BioCryst Pharmaceuticals when rated by MarketBeat users. However, 67.07% of users gave BioCryst Pharmaceuticals an outperform vote while only 65.60% of users gave OPKO Health an outperform vote. CompanyUnderperformOutperformOPKO HealthOutperform Votes51365.60% Underperform Votes26934.40% BioCryst PharmaceuticalsOutperform Votes49767.07% Underperform Votes24432.93% Is OPK or BCRX more profitable? OPKO Health has a net margin of -18.65% compared to BioCryst Pharmaceuticals' net margin of -30.01%. BioCryst Pharmaceuticals' return on equity of 0.00% beat OPKO Health's return on equity.Company Net Margins Return on Equity Return on Assets OPKO Health-18.65% -9.76% -6.46% BioCryst Pharmaceuticals -30.01%N/A -24.06% Does the media refer more to OPK or BCRX? In the previous week, BioCryst Pharmaceuticals had 42 more articles in the media than OPKO Health. MarketBeat recorded 44 mentions for BioCryst Pharmaceuticals and 2 mentions for OPKO Health. BioCryst Pharmaceuticals' average media sentiment score of 1.00 beat OPKO Health's score of 0.68 indicating that BioCryst Pharmaceuticals is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment OPKO Health 1 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive BioCryst Pharmaceuticals 16 Very Positive mention(s) 6 Positive mention(s) 8 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive SummaryOPKO Health beats BioCryst Pharmaceuticals on 10 of the 18 factors compared between the two stocks. Get OPKO Health News Delivered to You Automatically Sign up to receive the latest news and ratings for OPK and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart OPK vs. The Competition Export to ExcelMetricOPKO HealthPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$1.03B$6.27B$5.25B$8.48BDividend YieldN/A3.02%4.99%4.19%P/E Ratio-6.828.7026.5819.72Price / Sales1.49268.55398.82118.62Price / CashN/A65.8538.3134.62Price / Book0.726.246.674.51Net Income-$188.86M$143.73M$3.22B$248.02M7 Day Performance4.02%0.73%1.35%5.41%1 Month Performance-8.80%5.27%6.03%11.66%1 Year Performance-0.77%-6.79%13.84%6.32% OPKO Health Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)OPKOPKO Health4.3748 of 5 stars$1.26-3.1%$2.75+118.3%+3.2%$999.25M$689.41M-6.634,200BCRXBioCryst Pharmaceuticals4.6667 of 5 stars$11.03+23.5%$16.13+46.2%+78.7%$2.31B$450.71M-18.08530High Trading VolumeLGNDLigand Pharmaceuticals4.5234 of 5 stars$106.35-2.8%$146.43+37.7%+25.6%$2.05B$167.13M42.3780Earnings ReportAnalyst DowngradeInsider TradeNews CoverageFOLDAmicus Therapeutics4.2064 of 5 stars$6.53-2.1%$16.22+148.4%-33.4%$2.01B$528.30M-36.28480News CoveragePositive NewsMNKDMannKind2.8379 of 5 stars$4.96-0.8%$9.56+92.8%+7.0%$1.51B$285.50M70.86400Earnings ReportAnalyst RevisionNews CoveragePositive NewsDVAXDynavax Technologies4.195 of 5 stars$11.26-0.6%$20.50+82.1%-12.8%$1.38B$277.25M62.56350News CoverageCLDXCelldex Therapeutics1.5152 of 5 stars$20.29-1.8%$55.30+172.5%-51.1%$1.35B$7.02M-7.89150INVAInnoviva4.5335 of 5 stars$18.74+0.1%$55.00+193.5%+12.8%$1.17B$358.71M27.16100Earnings ReportNews CoveragePositive NewsNVAXNovavax3.6604 of 5 stars$6.27-2.2%$18.00+187.1%-52.8%$1.01B$682.16M-2.771,990Earnings ReportGERNGeron4.0036 of 5 stars$1.42+2.9%$5.38+278.5%-67.9%$904.42M$76.99M-4.4470Earnings ReportAnalyst RevisionGap UpMYGNMyriad Genetics4.0983 of 5 stars$7.70+1.9%$20.61+167.6%-83.5%$709.72M$837.60M-5.922,600 Related Companies and Tools Related Companies BCRX Competitors LGND Competitors FOLD Competitors MNKD Competitors DVAX Competitors CLDX Competitors INVA Competitors NVAX Competitors GERN Competitors MYGN Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:OPK) was last updated on 5/14/2025 by MarketBeat.com Staff From Our PartnersSilver Demand Is Soaring-Supply Can't Keep UpSilver demand hit 1.16 billion ounces in 2024-while supply fell short again for the fourth year in a row. 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