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BioCryst Pharmaceuticals (BCRX) Competitors

BioCryst Pharmaceuticals logo
$9.60 +0.80 (+9.09%)
Closing price 05/13/2026 04:00 PM Eastern
Extended Trading
$9.72 +0.12 (+1.20%)
As of 06:35 AM Eastern
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BCRX vs. HALO, RGEN, ALKS, LGND, and CLDX

Should you buy BioCryst Pharmaceuticals stock or one of its competitors? MarketBeat compares BioCryst Pharmaceuticals with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with BioCryst Pharmaceuticals include Halozyme Therapeutics (HALO), Repligen (RGEN), Alkermes (ALKS), Ligand Pharmaceuticals (LGND), and Celldex Therapeutics (CLDX). These companies are all part of the "biotechnology" industry.

How does BioCryst Pharmaceuticals compare to Halozyme Therapeutics?

Halozyme Therapeutics (NASDAQ:HALO) and BioCryst Pharmaceuticals (NASDAQ:BCRX) are both mid-cap medical companies, but which is the better business? We will compare the two businesses based on the strength of their earnings, media sentiment, profitability, dividends, analyst recommendations, risk, valuation and institutional ownership.

Halozyme Therapeutics has a net margin of 23.13% compared to BioCryst Pharmaceuticals' net margin of -51.71%. Halozyme Therapeutics' return on equity of 187.91% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Halozyme Therapeutics23.13% 187.91% 21.92%
BioCryst Pharmaceuticals -51.71%-76.36%60.12%

Halozyme Therapeutics presently has a consensus price target of $80.67, indicating a potential upside of 15.19%. BioCryst Pharmaceuticals has a consensus price target of $20.70, indicating a potential upside of 115.63%. Given BioCryst Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe BioCryst Pharmaceuticals is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Halozyme Therapeutics
1 Sell rating(s)
4 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.50
BioCryst Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.75

Halozyme Therapeutics has higher revenue and earnings than BioCryst Pharmaceuticals. BioCryst Pharmaceuticals is trading at a lower price-to-earnings ratio than Halozyme Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Halozyme Therapeutics$1.51B5.50$316.89M$2.7825.19
BioCryst Pharmaceuticals$885.72M2.75$263.86M-$1.78N/A

In the previous week, Halozyme Therapeutics had 12 more articles in the media than BioCryst Pharmaceuticals. MarketBeat recorded 30 mentions for Halozyme Therapeutics and 18 mentions for BioCryst Pharmaceuticals. Halozyme Therapeutics' average media sentiment score of 0.59 beat BioCryst Pharmaceuticals' score of 0.31 indicating that Halozyme Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Halozyme Therapeutics
10 Very Positive mention(s)
2 Positive mention(s)
10 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Positive
BioCryst Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
8 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral

Halozyme Therapeutics has a beta of 0.89, indicating that its stock price is 11% less volatile than the broader market. Comparatively, BioCryst Pharmaceuticals has a beta of 0.57, indicating that its stock price is 43% less volatile than the broader market.

97.8% of Halozyme Therapeutics shares are held by institutional investors. Comparatively, 85.9% of BioCryst Pharmaceuticals shares are held by institutional investors. 2.5% of Halozyme Therapeutics shares are held by insiders. Comparatively, 5.1% of BioCryst Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Summary

Halozyme Therapeutics beats BioCryst Pharmaceuticals on 11 of the 16 factors compared between the two stocks.

How does BioCryst Pharmaceuticals compare to Repligen?

Repligen (NASDAQ:RGEN) and BioCryst Pharmaceuticals (NASDAQ:BCRX) are both mid-cap medical companies, but which is the superior investment? We will compare the two companies based on the strength of their dividends, media sentiment, valuation, earnings, institutional ownership, analyst recommendations, risk and profitability.

Repligen has a net margin of 6.73% compared to BioCryst Pharmaceuticals' net margin of -51.71%. Repligen's return on equity of 4.88% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Repligen6.73% 4.88% 3.48%
BioCryst Pharmaceuticals -51.71%-76.36%60.12%

Repligen currently has a consensus price target of $169.62, indicating a potential upside of 58.47%. BioCryst Pharmaceuticals has a consensus price target of $20.70, indicating a potential upside of 115.63%. Given BioCryst Pharmaceuticals' higher probable upside, analysts clearly believe BioCryst Pharmaceuticals is more favorable than Repligen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Repligen
1 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
2 Strong Buy rating(s)
2.87
BioCryst Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.75

In the previous week, BioCryst Pharmaceuticals had 12 more articles in the media than Repligen. MarketBeat recorded 18 mentions for BioCryst Pharmaceuticals and 6 mentions for Repligen. Repligen's average media sentiment score of 0.75 beat BioCryst Pharmaceuticals' score of 0.31 indicating that Repligen is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Repligen
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
BioCryst Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
8 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral

97.6% of Repligen shares are owned by institutional investors. Comparatively, 85.9% of BioCryst Pharmaceuticals shares are owned by institutional investors. 0.6% of Repligen shares are owned by company insiders. Comparatively, 5.1% of BioCryst Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Repligen has a beta of 1.09, meaning that its share price is 9% more volatile than the broader market. Comparatively, BioCryst Pharmaceuticals has a beta of 0.57, meaning that its share price is 43% less volatile than the broader market.

BioCryst Pharmaceuticals has higher revenue and earnings than Repligen. BioCryst Pharmaceuticals is trading at a lower price-to-earnings ratio than Repligen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Repligen$738.26M8.18$48.89M$0.90118.92
BioCryst Pharmaceuticals$885.72M2.75$263.86M-$1.78N/A

Summary

Repligen beats BioCryst Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

How does BioCryst Pharmaceuticals compare to Alkermes?

BioCryst Pharmaceuticals (NASDAQ:BCRX) and Alkermes (NASDAQ:ALKS) are both mid-cap medical companies, but which is the better investment? We will compare the two companies based on the strength of their dividends, media sentiment, risk, institutional ownership, earnings, analyst recommendations, profitability and valuation.

Alkermes has a net margin of 9.78% compared to BioCryst Pharmaceuticals' net margin of -51.71%. Alkermes' return on equity of 9.26% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
BioCryst Pharmaceuticals-51.71% -76.36% 60.12%
Alkermes 9.78%9.26%5.66%

BioCryst Pharmaceuticals currently has a consensus price target of $20.70, indicating a potential upside of 115.63%. Alkermes has a consensus price target of $45.40, indicating a potential upside of 16.68%. Given BioCryst Pharmaceuticals' higher possible upside, research analysts clearly believe BioCryst Pharmaceuticals is more favorable than Alkermes.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioCryst Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.75
Alkermes
0 Sell rating(s)
5 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.76

In the previous week, BioCryst Pharmaceuticals had 2 more articles in the media than Alkermes. MarketBeat recorded 18 mentions for BioCryst Pharmaceuticals and 16 mentions for Alkermes. Alkermes' average media sentiment score of 0.50 beat BioCryst Pharmaceuticals' score of 0.31 indicating that Alkermes is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BioCryst Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
8 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral
Alkermes
5 Very Positive mention(s)
2 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

85.9% of BioCryst Pharmaceuticals shares are owned by institutional investors. Comparatively, 95.2% of Alkermes shares are owned by institutional investors. 5.1% of BioCryst Pharmaceuticals shares are owned by insiders. Comparatively, 4.6% of Alkermes shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

BioCryst Pharmaceuticals has a beta of 0.57, indicating that its stock price is 43% less volatile than the broader market. Comparatively, Alkermes has a beta of 0.31, indicating that its stock price is 69% less volatile than the broader market.

BioCryst Pharmaceuticals has higher earnings, but lower revenue than Alkermes. BioCryst Pharmaceuticals is trading at a lower price-to-earnings ratio than Alkermes, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioCryst Pharmaceuticals$885.72M2.75$263.86M-$1.78N/A
Alkermes$1.48B4.39$241.66M$0.9043.23

Summary

Alkermes beats BioCryst Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

How does BioCryst Pharmaceuticals compare to Ligand Pharmaceuticals?

BioCryst Pharmaceuticals (NASDAQ:BCRX) and Ligand Pharmaceuticals (NASDAQ:LGND) are both mid-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their risk, media sentiment, valuation, dividends, institutional ownership, analyst recommendations, earnings and profitability.

BioCryst Pharmaceuticals presently has a consensus price target of $20.70, suggesting a potential upside of 115.63%. Ligand Pharmaceuticals has a consensus price target of $257.71, suggesting a potential upside of 16.50%. Given BioCryst Pharmaceuticals' higher possible upside, analysts clearly believe BioCryst Pharmaceuticals is more favorable than Ligand Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioCryst Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.75
Ligand Pharmaceuticals
0 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
0 Strong Buy rating(s)
2.88

In the previous week, Ligand Pharmaceuticals had 1 more articles in the media than BioCryst Pharmaceuticals. MarketBeat recorded 19 mentions for Ligand Pharmaceuticals and 18 mentions for BioCryst Pharmaceuticals. Ligand Pharmaceuticals' average media sentiment score of 0.66 beat BioCryst Pharmaceuticals' score of 0.31 indicating that Ligand Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BioCryst Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
8 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral
Ligand Pharmaceuticals
5 Very Positive mention(s)
2 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Ligand Pharmaceuticals has a net margin of 55.95% compared to BioCryst Pharmaceuticals' net margin of -51.71%. Ligand Pharmaceuticals' return on equity of 16.19% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
BioCryst Pharmaceuticals-51.71% -76.36% 60.12%
Ligand Pharmaceuticals 55.95%16.19%11.13%

85.9% of BioCryst Pharmaceuticals shares are owned by institutional investors. Comparatively, 91.3% of Ligand Pharmaceuticals shares are owned by institutional investors. 5.1% of BioCryst Pharmaceuticals shares are owned by insiders. Comparatively, 7.0% of Ligand Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

BioCryst Pharmaceuticals has higher revenue and earnings than Ligand Pharmaceuticals. BioCryst Pharmaceuticals is trading at a lower price-to-earnings ratio than Ligand Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioCryst Pharmaceuticals$885.72M2.75$263.86M-$1.78N/A
Ligand Pharmaceuticals$268.09M16.54$124.45M$7.3730.01

BioCryst Pharmaceuticals has a beta of 0.57, indicating that its share price is 43% less volatile than the broader market. Comparatively, Ligand Pharmaceuticals has a beta of 1.2, indicating that its share price is 20% more volatile than the broader market.

Summary

Ligand Pharmaceuticals beats BioCryst Pharmaceuticals on 11 of the 16 factors compared between the two stocks.

How does BioCryst Pharmaceuticals compare to Celldex Therapeutics?

Celldex Therapeutics (NASDAQ:CLDX) and BioCryst Pharmaceuticals (NASDAQ:BCRX) are both mid-cap medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their media sentiment, profitability, dividends, risk, earnings, institutional ownership, analyst recommendations and valuation.

85.9% of BioCryst Pharmaceuticals shares are owned by institutional investors. 5.2% of Celldex Therapeutics shares are owned by insiders. Comparatively, 5.1% of BioCryst Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

In the previous week, Celldex Therapeutics and Celldex Therapeutics both had 18 articles in the media. Celldex Therapeutics' average media sentiment score of 0.43 beat BioCryst Pharmaceuticals' score of 0.31 indicating that Celldex Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Celldex Therapeutics
3 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
BioCryst Pharmaceuticals
4 Very Positive mention(s)
0 Positive mention(s)
8 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral

Celldex Therapeutics currently has a consensus target price of $49.78, indicating a potential upside of 53.12%. BioCryst Pharmaceuticals has a consensus target price of $20.70, indicating a potential upside of 115.63%. Given BioCryst Pharmaceuticals' higher probable upside, analysts clearly believe BioCryst Pharmaceuticals is more favorable than Celldex Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Celldex Therapeutics
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.80
BioCryst Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.75

Celldex Therapeutics has a beta of 0.98, indicating that its stock price is 2% less volatile than the broader market. Comparatively, BioCryst Pharmaceuticals has a beta of 0.57, indicating that its stock price is 43% less volatile than the broader market.

BioCryst Pharmaceuticals has higher revenue and earnings than Celldex Therapeutics. Celldex Therapeutics is trading at a lower price-to-earnings ratio than BioCryst Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Celldex Therapeutics$1.54M1,656.95-$258.76M-$4.26N/A
BioCryst Pharmaceuticals$885.72M2.75$263.86M-$1.78N/A

Celldex Therapeutics has a net margin of 0.00% compared to BioCryst Pharmaceuticals' net margin of -51.71%. Celldex Therapeutics' return on equity of -50.72% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Celldex TherapeuticsN/A -50.72% -46.59%
BioCryst Pharmaceuticals -51.71%-76.36%60.12%

Summary

Celldex Therapeutics and BioCryst Pharmaceuticals tied by winning 8 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding BCRX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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BCRX vs. The Competition

MetricBioCryst PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$2.24B$3.04B$6.30B$12.20B
Dividend YieldN/A1.96%2.79%5.30%
P/E Ratio-5.3918.8621.0325.58
Price / Sales2.75289.31548.9478.80
Price / Cash7.1156.5342.9455.34
Price / Book-4.404.359.846.66
Net Income$263.86M$72.19M$3.55B$333.63M
7 Day Performance7.87%-1.05%-0.52%-0.12%
1 Month Performance-0.72%-0.02%1.21%3.93%
1 Year Performance-2.54%46.31%41.24%36.07%

BioCryst Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
BCRX
BioCryst Pharmaceuticals
3.7225 of 5 stars
$9.60
+9.1%
$20.70
+115.6%
-4.6%$2.24B$885.72MN/A530
HALO
Halozyme Therapeutics
3.9405 of 5 stars
$66.41
+3.6%
$79.11
+19.1%
+39.4%$7.60B$1.40B26.67390
RGEN
Repligen
3.9494 of 5 stars
$115.91
-6.1%
$169.62
+46.3%
-18.6%$6.96B$738.26M128.792,000
ALKS
Alkermes
2.8147 of 5 stars
$35.47
+1.4%
$45.21
+27.5%
+26.2%$5.83B$1.48B39.412,050
LGND
Ligand Pharmaceuticals
3.819 of 5 stars
$220.48
-0.4%
$257.71
+16.9%
+109.4%$4.44B$268.09M29.9280

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This page (NASDAQ:BCRX) was last updated on 5/14/2026 by MarketBeat.com Staff.
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