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BioCryst Pharmaceuticals (BCRX) Competitors

BioCryst Pharmaceuticals logo
$9.56 -0.10 (-1.04%)
As of 08/21/2026 04:00 PM Eastern

BCRX vs. KRYS, NUVL, KYMR, IONS, and CYTK

Should you buy BioCryst Pharmaceuticals stock or one of its competitors? BioCryst Pharmaceuticals's main competitors and comparable companies include Krystal Biotech (KRYS), Nuvalent (NUVL), Kymera Therapeutics (KYMR), Ionis Pharmaceuticals (IONS), and Cytokinetics (CYTK). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does BioCryst Pharmaceuticals compare to Krystal Biotech?

BioCryst Pharmaceuticals (NASDAQ:BCRX) and Krystal Biotech (NASDAQ:KRYS) are both healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their dividends, valuation, profitability, institutional ownership, risk, analyst recommendations, earnings and media sentiment.

Krystal Biotech has a net margin of 54.82% compared to BioCryst Pharmaceuticals' net margin of -40.90%. Krystal Biotech's return on equity of 19.34% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
BioCryst Pharmaceuticals-40.90% -86.89% 66.37%
Krystal Biotech 54.82%19.34%17.65%

85.9% of BioCryst Pharmaceuticals shares are held by institutional investors. Comparatively, 86.3% of Krystal Biotech shares are held by institutional investors. 3.8% of BioCryst Pharmaceuticals shares are held by insiders. Comparatively, 13.1% of Krystal Biotech shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

BioCryst Pharmaceuticals has higher revenue and earnings than Krystal Biotech. BioCryst Pharmaceuticals is trading at a lower price-to-earnings ratio than Krystal Biotech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioCryst Pharmaceuticals$940.61M2.60$263.86M-$1.50N/A
Krystal Biotech$389.13M26.36$204.83M$7.9843.43

BioCryst Pharmaceuticals has a beta of 0.55, suggesting that its stock price is 45% less volatile than the broader market. Comparatively, Krystal Biotech has a beta of 0.53, suggesting that its stock price is 47% less volatile than the broader market.

BioCryst Pharmaceuticals presently has a consensus price target of $20.60, suggesting a potential upside of 115.48%. Krystal Biotech has a consensus price target of $365.40, suggesting a potential upside of 5.43%. Given BioCryst Pharmaceuticals' higher possible upside, analysts clearly believe BioCryst Pharmaceuticals is more favorable than Krystal Biotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioCryst Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.67
Krystal Biotech
0 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.92

In the previous week, BioCryst Pharmaceuticals and BioCryst Pharmaceuticals both had 7 articles in the media. Krystal Biotech's average media sentiment score of 1.30 beat BioCryst Pharmaceuticals' score of 0.95 indicating that Krystal Biotech is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BioCryst Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Krystal Biotech
5 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Krystal Biotech beats BioCryst Pharmaceuticals on 11 of the 16 factors compared between the two stocks.

How does BioCryst Pharmaceuticals compare to Nuvalent?

BioCryst Pharmaceuticals (NASDAQ:BCRX) and Nuvalent (NASDAQ:NUVL) are both mid-cap healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their institutional ownership, media sentiment, valuation, dividends, profitability, earnings, analyst recommendations and risk.

In the previous week, BioCryst Pharmaceuticals had 7 more articles in the media than Nuvalent. MarketBeat recorded 7 mentions for BioCryst Pharmaceuticals and 0 mentions for Nuvalent. BioCryst Pharmaceuticals' average media sentiment score of 0.95 beat Nuvalent's score of 0.00 indicating that BioCryst Pharmaceuticals is being referred to more favorably in the media.

Company Overall Sentiment
BioCryst Pharmaceuticals Positive
Nuvalent Neutral

Nuvalent has a net margin of 0.00% compared to BioCryst Pharmaceuticals' net margin of -40.90%. Nuvalent's return on equity of -40.11% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
BioCryst Pharmaceuticals-40.90% -86.89% 66.37%
Nuvalent N/A -40.11%-35.43%

85.9% of BioCryst Pharmaceuticals shares are held by institutional investors. Comparatively, 97.3% of Nuvalent shares are held by institutional investors. 3.8% of BioCryst Pharmaceuticals shares are held by insiders. Comparatively, 5.0% of Nuvalent shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

BioCryst Pharmaceuticals has higher revenue and earnings than Nuvalent. Nuvalent is trading at a lower price-to-earnings ratio than BioCryst Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioCryst Pharmaceuticals$940.61M2.60$263.86M-$1.50N/A
NuvalentN/AN/A-$425.38M-$6.06N/A

BioCryst Pharmaceuticals has a beta of 0.55, meaning that its stock price is 45% less volatile than the broader market. Comparatively, Nuvalent has a beta of 1.14, meaning that its stock price is 14% more volatile than the broader market.

BioCryst Pharmaceuticals presently has a consensus price target of $20.60, suggesting a potential upside of 115.48%. Nuvalent has a consensus price target of $127.73, suggesting a potential upside of 3.04%. Given BioCryst Pharmaceuticals' stronger consensus rating and higher probable upside, research analysts plainly believe BioCryst Pharmaceuticals is more favorable than Nuvalent.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioCryst Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.67
Nuvalent
1 Sell rating(s)
15 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.15

Summary

BioCryst Pharmaceuticals beats Nuvalent on 10 of the 15 factors compared between the two stocks.

How does BioCryst Pharmaceuticals compare to Kymera Therapeutics?

Kymera Therapeutics (NASDAQ:KYMR) and BioCryst Pharmaceuticals (NASDAQ:BCRX) are both mid-cap healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their dividends, valuation, analyst recommendations, media sentiment, risk, profitability, institutional ownership and earnings.

Kymera Therapeutics has a beta of 1.95, meaning that its share price is 95% more volatile than the broader market. Comparatively, BioCryst Pharmaceuticals has a beta of 0.55, meaning that its share price is 45% less volatile than the broader market.

In the previous week, Kymera Therapeutics had 2 more articles in the media than BioCryst Pharmaceuticals. MarketBeat recorded 9 mentions for Kymera Therapeutics and 7 mentions for BioCryst Pharmaceuticals. Kymera Therapeutics' average media sentiment score of 1.24 beat BioCryst Pharmaceuticals' score of 0.95 indicating that Kymera Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Kymera Therapeutics
6 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
BioCryst Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Kymera Therapeutics currently has a consensus price target of $125.65, indicating a potential upside of 4.88%. BioCryst Pharmaceuticals has a consensus price target of $20.60, indicating a potential upside of 115.48%. Given BioCryst Pharmaceuticals' higher possible upside, analysts plainly believe BioCryst Pharmaceuticals is more favorable than Kymera Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Kymera Therapeutics
1 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
0 Strong Buy rating(s)
2.83
BioCryst Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.67

85.9% of BioCryst Pharmaceuticals shares are owned by institutional investors. 16.0% of Kymera Therapeutics shares are owned by insiders. Comparatively, 3.8% of BioCryst Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

BioCryst Pharmaceuticals has higher revenue and earnings than Kymera Therapeutics. Kymera Therapeutics is trading at a lower price-to-earnings ratio than BioCryst Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Kymera Therapeutics$39.21M254.05-$311.35M-$3.24N/A
BioCryst Pharmaceuticals$940.61M2.60$263.86M-$1.50N/A

BioCryst Pharmaceuticals has a net margin of -40.90% compared to Kymera Therapeutics' net margin of -285.33%. Kymera Therapeutics' return on equity of -21.22% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Kymera Therapeutics-285.33% -21.22% -19.21%
BioCryst Pharmaceuticals -40.90%-86.89%66.37%

Summary

Kymera Therapeutics and BioCryst Pharmaceuticals tied by winning 8 of the 16 factors compared between the two stocks.

How does BioCryst Pharmaceuticals compare to Ionis Pharmaceuticals?

BioCryst Pharmaceuticals (NASDAQ:BCRX) and Ionis Pharmaceuticals (NASDAQ:IONS) are both mid-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their earnings, profitability, institutional ownership, valuation, media sentiment, dividends, analyst recommendations and risk.

BioCryst Pharmaceuticals has a net margin of -40.90% compared to Ionis Pharmaceuticals' net margin of -64.76%. BioCryst Pharmaceuticals' return on equity of -86.89% beat Ionis Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
BioCryst Pharmaceuticals-40.90% -86.89% 66.37%
Ionis Pharmaceuticals -64.76%-111.08%-17.41%

BioCryst Pharmaceuticals presently has a consensus price target of $20.60, suggesting a potential upside of 115.48%. Ionis Pharmaceuticals has a consensus price target of $94.15, suggesting a potential upside of 57.60%. Given BioCryst Pharmaceuticals' higher probable upside, equities research analysts plainly believe BioCryst Pharmaceuticals is more favorable than Ionis Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioCryst Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.67
Ionis Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.73

In the previous week, Ionis Pharmaceuticals had 11 more articles in the media than BioCryst Pharmaceuticals. MarketBeat recorded 18 mentions for Ionis Pharmaceuticals and 7 mentions for BioCryst Pharmaceuticals. Ionis Pharmaceuticals' average media sentiment score of 1.08 beat BioCryst Pharmaceuticals' score of 0.95 indicating that Ionis Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BioCryst Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Ionis Pharmaceuticals
9 Very Positive mention(s)
2 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

BioCryst Pharmaceuticals has higher earnings, but lower revenue than Ionis Pharmaceuticals. Ionis Pharmaceuticals is trading at a lower price-to-earnings ratio than BioCryst Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioCryst Pharmaceuticals$940.61M2.60$263.86M-$1.50N/A
Ionis Pharmaceuticals$944M10.52-$381.39M-$3.46N/A

BioCryst Pharmaceuticals has a beta of 0.55, meaning that its stock price is 45% less volatile than the broader market. Comparatively, Ionis Pharmaceuticals has a beta of 0.41, meaning that its stock price is 59% less volatile than the broader market.

85.9% of BioCryst Pharmaceuticals shares are owned by institutional investors. Comparatively, 93.9% of Ionis Pharmaceuticals shares are owned by institutional investors. 3.8% of BioCryst Pharmaceuticals shares are owned by insiders. Comparatively, 1.8% of Ionis Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Summary

BioCryst Pharmaceuticals beats Ionis Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does BioCryst Pharmaceuticals compare to Cytokinetics?

Cytokinetics (NASDAQ:CYTK) and BioCryst Pharmaceuticals (NASDAQ:BCRX) are both mid-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their profitability, earnings, risk, dividends, analyst recommendations, media sentiment, institutional ownership and valuation.

BioCryst Pharmaceuticals has higher revenue and earnings than Cytokinetics. Cytokinetics is trading at a lower price-to-earnings ratio than BioCryst Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Cytokinetics$88.04M108.60-$784.96M-$7.22N/A
BioCryst Pharmaceuticals$940.61M2.60$263.86M-$1.50N/A

Cytokinetics presently has a consensus target price of $102.20, indicating a potential upside of 33.00%. BioCryst Pharmaceuticals has a consensus target price of $20.60, indicating a potential upside of 115.48%. Given BioCryst Pharmaceuticals' higher probable upside, analysts clearly believe BioCryst Pharmaceuticals is more favorable than Cytokinetics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cytokinetics
1 Sell rating(s)
1 Hold rating(s)
19 Buy rating(s)
0 Strong Buy rating(s)
2.86
BioCryst Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.67

In the previous week, Cytokinetics had 1 more articles in the media than BioCryst Pharmaceuticals. MarketBeat recorded 8 mentions for Cytokinetics and 7 mentions for BioCryst Pharmaceuticals. BioCryst Pharmaceuticals' average media sentiment score of 0.95 beat Cytokinetics' score of 0.65 indicating that BioCryst Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Cytokinetics
4 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
BioCryst Pharmaceuticals
4 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Cytokinetics has a beta of 0.38, suggesting that its share price is 62% less volatile than the broader market. Comparatively, BioCryst Pharmaceuticals has a beta of 0.55, suggesting that its share price is 45% less volatile than the broader market.

85.9% of BioCryst Pharmaceuticals shares are held by institutional investors. 2.6% of Cytokinetics shares are held by insiders. Comparatively, 3.8% of BioCryst Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

BioCryst Pharmaceuticals has a net margin of -40.90% compared to Cytokinetics' net margin of -1,321.12%. Cytokinetics' return on equity of 0.00% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Cytokinetics-1,321.12% N/A -51.01%
BioCryst Pharmaceuticals -40.90%-86.89%66.37%

Summary

BioCryst Pharmaceuticals beats Cytokinetics on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding BCRX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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BCRX vs. The Competition

MetricBioCryst PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$2.44B$4.01B$7.37B$12.85B
Dividend YieldN/A3.64%2.53%11.08%
P/E Ratio-6.3711.62272.6024.24
Price / Sales2.601,338.17618.9699.81
Price / Cash7.71105.1478.6253.99
Price / Book-5.3716.8013.056.20
Net Income$263.86M-$12.50M$3.47B$348.59M
7 Day Performance-1.85%3.29%2.09%0.08%
1 Month Performance1.92%8.23%6.64%3.88%
1 Year Performance11.68%55.05%25.02%16.98%

BioCryst Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
BCRX
BioCryst Pharmaceuticals
2.8354 of 5 stars
$9.56
-1.0%
$20.60
+115.5%
+11.7%$2.44B$940.61MN/A530
KRYS
Krystal Biotech
4.1259 of 5 stars
$335.73
+1.0%
$365.40
+8.8%
+130.3%$9.83B$440.48M42.07210
NUVL
Nuvalent
2.1252 of 5 stars
$123.96
flat
$127.73
+3.0%
N/A$9.79BN/AN/A40
KYMR
Kymera Therapeutics
1.5005 of 5 stars
$121.41
+3.4%
$125.65
+3.5%
+171.7%$9.76B$39.21MN/A170
IONS
Ionis Pharmaceuticals
3.5653 of 5 stars
$58.63
+2.4%
$94.65
+61.4%
+39.9%$9.51B$944MN/A1,402

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This page (NASDAQ:BCRX) was last updated on 8/23/2026 by MarketBeat.com Staff.
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