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Halozyme Therapeutics (HALO) Competitors

Halozyme Therapeutics logo
$108.17 +2.05 (+1.93%)
As of 08/21/2026 04:00 PM Eastern

HALO vs. NTRA, RVMD, BIIB, ALNY, and INSM

Should you buy Halozyme Therapeutics stock or one of its competitors? Halozyme Therapeutics's main competitors and comparable companies include Natera (NTRA), Revolution Medicines (RVMD), Biogen (BIIB), Alnylam Pharmaceuticals (ALNY), and Insmed (INSM). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Halozyme Therapeutics compare to Natera?

Natera (NASDAQ:NTRA) and Halozyme Therapeutics (NASDAQ:HALO) are both large-cap healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their valuation, risk, profitability, institutional ownership, media sentiment, dividends, earnings and analyst recommendations.

99.9% of Natera shares are owned by institutional investors. Comparatively, 97.8% of Halozyme Therapeutics shares are owned by institutional investors. 5.1% of Natera shares are owned by insiders. Comparatively, 2.5% of Halozyme Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Natera presently has a consensus price target of $319.38, suggesting a potential downside of 3.81%. Halozyme Therapeutics has a consensus price target of $91.20, suggesting a potential downside of 15.69%. Given Natera's stronger consensus rating and higher possible upside, equities analysts plainly believe Natera is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Natera
1 Sell rating(s)
4 Hold rating(s)
15 Buy rating(s)
2 Strong Buy rating(s)
2.82
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62

Halozyme Therapeutics has a net margin of 24.86% compared to Natera's net margin of -7.11%. Halozyme Therapeutics' return on equity of 260.98% beat Natera's return on equity.

Company Net Margins Return on Equity Return on Assets
Natera-7.11% -11.38% -7.87%
Halozyme Therapeutics 24.86%260.98%23.91%

Halozyme Therapeutics has lower revenue, but higher earnings than Natera. Natera is trading at a lower price-to-earnings ratio than Halozyme Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Natera$2.31B20.75-$208.16M-$1.36N/A
Halozyme Therapeutics$1.66B7.38$316.89M$3.3532.29

Natera has a beta of 1.51, meaning that its share price is 51% more volatile than the broader market. Comparatively, Halozyme Therapeutics has a beta of 0.85, meaning that its share price is 15% less volatile than the broader market.

In the previous week, Natera had 15 more articles in the media than Halozyme Therapeutics. MarketBeat recorded 30 mentions for Natera and 15 mentions for Halozyme Therapeutics. Natera's average media sentiment score of 1.34 beat Halozyme Therapeutics' score of 1.04 indicating that Natera is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Natera
25 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Halozyme Therapeutics
10 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Natera beats Halozyme Therapeutics on 11 of the 17 factors compared between the two stocks.

How does Halozyme Therapeutics compare to Revolution Medicines?

Revolution Medicines (NASDAQ:RVMD) and Halozyme Therapeutics (NASDAQ:HALO) are both large-cap healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their valuation, earnings, institutional ownership, media sentiment, profitability, dividends, risk and analyst recommendations.

94.3% of Revolution Medicines shares are held by institutional investors. Comparatively, 97.8% of Halozyme Therapeutics shares are held by institutional investors. 7.6% of Revolution Medicines shares are held by insiders. Comparatively, 2.5% of Halozyme Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Revolution Medicines currently has a consensus price target of $167.89, suggesting a potential downside of 19.85%. Halozyme Therapeutics has a consensus price target of $91.20, suggesting a potential downside of 15.69%. Given Halozyme Therapeutics' higher probable upside, analysts plainly believe Halozyme Therapeutics is more favorable than Revolution Medicines.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Revolution Medicines
1 Sell rating(s)
1 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.90
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62

Revolution Medicines has a beta of 1.39, indicating that its stock price is 39% more volatile than the broader market. Comparatively, Halozyme Therapeutics has a beta of 0.85, indicating that its stock price is 15% less volatile than the broader market.

Halozyme Therapeutics has higher revenue and earnings than Revolution Medicines. Revolution Medicines is trading at a lower price-to-earnings ratio than Halozyme Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Revolution Medicines$11.58M3,877.00-$1.13B-$8.82N/A
Halozyme Therapeutics$1.66B7.38$316.89M$3.3532.29

Halozyme Therapeutics has a net margin of 24.86% compared to Revolution Medicines' net margin of 0.00%. Halozyme Therapeutics' return on equity of 260.98% beat Revolution Medicines' return on equity.

Company Net Margins Return on Equity Return on Assets
Revolution MedicinesN/A -88.20% -57.85%
Halozyme Therapeutics 24.86%260.98%23.91%

In the previous week, Halozyme Therapeutics had 3 more articles in the media than Revolution Medicines. MarketBeat recorded 15 mentions for Halozyme Therapeutics and 12 mentions for Revolution Medicines. Revolution Medicines' average media sentiment score of 1.37 beat Halozyme Therapeutics' score of 1.04 indicating that Revolution Medicines is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Revolution Medicines
10 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Positive
Halozyme Therapeutics
10 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Halozyme Therapeutics beats Revolution Medicines on 10 of the 17 factors compared between the two stocks.

How does Halozyme Therapeutics compare to Biogen?

Halozyme Therapeutics (NASDAQ:HALO) and Biogen (NASDAQ:BIIB) are both large-cap healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their media sentiment, risk, earnings, profitability, institutional ownership, dividends, analyst recommendations and valuation.

Halozyme Therapeutics has a beta of 0.85, suggesting that its stock price is 15% less volatile than the broader market. Comparatively, Biogen has a beta of 0.17, suggesting that its stock price is 83% less volatile than the broader market.

Biogen has higher revenue and earnings than Halozyme Therapeutics. Halozyme Therapeutics is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Halozyme Therapeutics$1.66B7.38$316.89M$3.3532.29
Biogen$10.03B3.19$1.29B$5.6538.37

Halozyme Therapeutics has a net margin of 24.86% compared to Biogen's net margin of 8.32%. Halozyme Therapeutics' return on equity of 260.98% beat Biogen's return on equity.

Company Net Margins Return on Equity Return on Assets
Halozyme Therapeutics24.86% 260.98% 23.91%
Biogen 8.32%11.18%6.88%

In the previous week, Biogen had 13 more articles in the media than Halozyme Therapeutics. MarketBeat recorded 28 mentions for Biogen and 15 mentions for Halozyme Therapeutics. Biogen's average media sentiment score of 1.35 beat Halozyme Therapeutics' score of 1.04 indicating that Biogen is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Halozyme Therapeutics
10 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Biogen
22 Very Positive mention(s)
3 Positive mention(s)
2 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

97.8% of Halozyme Therapeutics shares are owned by institutional investors. Comparatively, 87.9% of Biogen shares are owned by institutional investors. 2.5% of Halozyme Therapeutics shares are owned by company insiders. Comparatively, 0.3% of Biogen shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Halozyme Therapeutics currently has a consensus target price of $91.20, suggesting a potential downside of 15.69%. Biogen has a consensus target price of $227.07, suggesting a potential upside of 4.75%. Given Biogen's higher probable upside, analysts plainly believe Biogen is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62
Biogen
1 Sell rating(s)
13 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.58

Summary

Biogen beats Halozyme Therapeutics on 9 of the 17 factors compared between the two stocks.

How does Halozyme Therapeutics compare to Alnylam Pharmaceuticals?

Alnylam Pharmaceuticals (NASDAQ:ALNY) and Halozyme Therapeutics (NASDAQ:HALO) are both large-cap healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their earnings, dividends, analyst recommendations, media sentiment, profitability, risk, institutional ownership and valuation.

93.0% of Alnylam Pharmaceuticals shares are owned by institutional investors. Comparatively, 97.8% of Halozyme Therapeutics shares are owned by institutional investors. 0.9% of Alnylam Pharmaceuticals shares are owned by insiders. Comparatively, 2.5% of Halozyme Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Halozyme Therapeutics has lower revenue, but higher earnings than Alnylam Pharmaceuticals. Halozyme Therapeutics is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alnylam Pharmaceuticals$4.80B6.58$313.75M$5.3843.91
Halozyme Therapeutics$1.66B7.38$316.89M$3.3532.29

In the previous week, Alnylam Pharmaceuticals had 10 more articles in the media than Halozyme Therapeutics. MarketBeat recorded 25 mentions for Alnylam Pharmaceuticals and 15 mentions for Halozyme Therapeutics. Halozyme Therapeutics' average media sentiment score of 1.04 beat Alnylam Pharmaceuticals' score of 0.81 indicating that Halozyme Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alnylam Pharmaceuticals
11 Very Positive mention(s)
1 Positive mention(s)
10 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Halozyme Therapeutics
10 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Halozyme Therapeutics has a net margin of 24.86% compared to Alnylam Pharmaceuticals' net margin of 15.26%. Halozyme Therapeutics' return on equity of 260.98% beat Alnylam Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Alnylam Pharmaceuticals15.26% 84.93% 14.30%
Halozyme Therapeutics 24.86%260.98%23.91%

Alnylam Pharmaceuticals presently has a consensus price target of $386.62, suggesting a potential upside of 63.67%. Halozyme Therapeutics has a consensus price target of $91.20, suggesting a potential downside of 15.69%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, equities analysts plainly believe Alnylam Pharmaceuticals is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
15 Buy rating(s)
4 Strong Buy rating(s)
2.96
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62

Alnylam Pharmaceuticals has a beta of 0.3, suggesting that its share price is 70% less volatile than the broader market. Comparatively, Halozyme Therapeutics has a beta of 0.85, suggesting that its share price is 15% less volatile than the broader market.

Summary

Halozyme Therapeutics beats Alnylam Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Halozyme Therapeutics compare to Insmed?

Halozyme Therapeutics (NASDAQ:HALO) and Insmed (NASDAQ:INSM) are both large-cap healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their profitability, dividends, valuation, analyst recommendations, media sentiment, earnings, risk and institutional ownership.

Halozyme Therapeutics presently has a consensus target price of $91.20, suggesting a potential downside of 15.69%. Insmed has a consensus target price of $205.52, suggesting a potential upside of 63.41%. Given Insmed's stronger consensus rating and higher probable upside, analysts clearly believe Insmed is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62
Insmed
1 Sell rating(s)
0 Hold rating(s)
22 Buy rating(s)
2 Strong Buy rating(s)
3.00

Halozyme Therapeutics has a beta of 0.85, indicating that its share price is 15% less volatile than the broader market. Comparatively, Insmed has a beta of 0.81, indicating that its share price is 19% less volatile than the broader market.

Halozyme Therapeutics has higher revenue and earnings than Insmed. Insmed is trading at a lower price-to-earnings ratio than Halozyme Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Halozyme Therapeutics$1.66B7.38$316.89M$3.3532.29
Insmed$606.42M45.29-$1.28B-$4.11N/A

97.8% of Halozyme Therapeutics shares are held by institutional investors. 2.5% of Halozyme Therapeutics shares are held by company insiders. Comparatively, 2.1% of Insmed shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

In the previous week, Halozyme Therapeutics had 15 more articles in the media than Insmed. MarketBeat recorded 15 mentions for Halozyme Therapeutics and 0 mentions for Insmed. Insmed's average media sentiment score of 1.84 beat Halozyme Therapeutics' score of 1.04 indicating that Insmed is being referred to more favorably in the news media.

Company Overall Sentiment
Halozyme Therapeutics Positive
Insmed Very Positive

Halozyme Therapeutics has a net margin of 24.86% compared to Insmed's net margin of -76.94%. Halozyme Therapeutics' return on equity of 260.98% beat Insmed's return on equity.

Company Net Margins Return on Equity Return on Assets
Halozyme Therapeutics24.86% 260.98% 23.91%
Insmed -76.94%-123.94%-44.30%

Summary

Halozyme Therapeutics beats Insmed on 11 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding HALO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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HALO vs. The Competition

MetricHalozyme TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$12.28B$4.01B$7.37B$12.85B
Dividend YieldN/A3.64%2.53%11.08%
P/E Ratio32.2911.62272.6024.24
Price / Sales7.381,338.17618.9699.78
Price / Cash22.67105.1478.6253.99
Price / Book85.8516.8013.056.20
Net Income$316.89M-$12.50M$3.47B$348.59M
7 Day Performance9.64%3.29%2.09%0.08%
1 Month Performance33.81%8.23%6.64%3.88%
1 Year Performance50.61%55.05%25.02%16.98%

Halozyme Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
HALO
Halozyme Therapeutics
3.8838 of 5 stars
$108.17
+1.9%
$91.20
-15.7%
+50.6%$12.28B$1.66B32.29390
NTRA
Natera
2.5905 of 5 stars
$314.18
+1.4%
$319.38
+1.7%
+100.5%$44.67B$2.31BN/A6,140
RVMD
Revolution Medicines
2.5369 of 5 stars
$212.00
+4.1%
$166.33
-21.5%
+466.0%$43.66B$11.58MN/A250
BIIB
Biogen
3.9629 of 5 stars
$209.15
-0.3%
$227.07
+8.6%
+55.6%$31.00B$9.89B37.027,500
ALNY
Alnylam Pharmaceuticals
4.9363 of 5 stars
$224.60
-1.8%
$393.86
+75.4%
-48.0%$30.60B$3.71B41.752,770

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This page (NASDAQ:HALO) was last updated on 8/23/2026 by MarketBeat.com Staff.
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