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Halozyme Therapeutics (HALO) Competitors

Halozyme Therapeutics logo
$107.20 +0.20 (+0.19%)
Closing price 09/11/2026 04:00 PM Eastern
Extended Trading
$106.32 -0.88 (-0.82%)
As of 09/11/2026 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

HALO vs. NTRA, RVMD, BIIB, ALNY, and INSM

Should you buy Halozyme Therapeutics stock or one of its competitors? Halozyme Therapeutics's main competitors and comparable companies include Natera (NTRA), Revolution Medicines (RVMD), Biogen (BIIB), Alnylam Pharmaceuticals (ALNY), and Insmed (INSM). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Halozyme Therapeutics compare to Natera?

Natera (NASDAQ:NTRA) and Halozyme Therapeutics (NASDAQ:HALO) are both large-cap healthcare companies, but which is the superior business? We will compare the two businesses based on the strength of their dividends, valuation, risk, analyst recommendations, institutional ownership, earnings, profitability and media sentiment.

Halozyme Therapeutics has lower revenue, but higher earnings than Natera. Natera is trading at a lower price-to-earnings ratio than Halozyme Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Natera$2.31B20.56-$208.16M-$1.36N/A
Halozyme Therapeutics$1.40B8.71$316.89M$3.3532.00

Halozyme Therapeutics has a net margin of 24.86% compared to Natera's net margin of -7.11%. Halozyme Therapeutics' return on equity of 260.98% beat Natera's return on equity.

Company Net Margins Return on Equity Return on Assets
Natera-7.11% -11.38% -7.87%
Halozyme Therapeutics 24.86%260.98%23.91%

99.9% of Natera shares are held by institutional investors. Comparatively, 97.8% of Halozyme Therapeutics shares are held by institutional investors. 5.1% of Natera shares are held by insiders. Comparatively, 2.5% of Halozyme Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Natera has a beta of 1.54, indicating that its stock price is 54% more volatile than the broader market. Comparatively, Halozyme Therapeutics has a beta of 0.88, indicating that its stock price is 12% less volatile than the broader market.

In the previous week, Natera had 6 more articles in the media than Halozyme Therapeutics. MarketBeat recorded 19 mentions for Natera and 13 mentions for Halozyme Therapeutics. Natera's average media sentiment score of 1.21 beat Halozyme Therapeutics' score of 1.20 indicating that Natera is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Natera
11 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Halozyme Therapeutics
9 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Natera currently has a consensus price target of $330.83, suggesting a potential upside of 0.58%. Halozyme Therapeutics has a consensus price target of $91.20, suggesting a potential downside of 14.93%. Given Natera's stronger consensus rating and higher possible upside, research analysts clearly believe Natera is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Natera
1 Sell rating(s)
4 Hold rating(s)
16 Buy rating(s)
2 Strong Buy rating(s)
2.83
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62

Summary

Natera beats Halozyme Therapeutics on 11 of the 17 factors compared between the two stocks.

How does Halozyme Therapeutics compare to Revolution Medicines?

Halozyme Therapeutics (NASDAQ:HALO) and Revolution Medicines (NASDAQ:RVMD) are both large-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their media sentiment, profitability, valuation, dividends, earnings, analyst recommendations, institutional ownership and risk.

97.8% of Halozyme Therapeutics shares are owned by institutional investors. Comparatively, 94.3% of Revolution Medicines shares are owned by institutional investors. 2.5% of Halozyme Therapeutics shares are owned by insiders. Comparatively, 7.6% of Revolution Medicines shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Halozyme Therapeutics currently has a consensus target price of $91.20, suggesting a potential downside of 14.93%. Revolution Medicines has a consensus target price of $226.17, suggesting a potential upside of 10.99%. Given Revolution Medicines' stronger consensus rating and higher possible upside, analysts clearly believe Revolution Medicines is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62
Revolution Medicines
1 Sell rating(s)
1 Hold rating(s)
17 Buy rating(s)
2 Strong Buy rating(s)
2.95

In the previous week, Halozyme Therapeutics and Halozyme Therapeutics both had 13 articles in the media. Halozyme Therapeutics' average media sentiment score of 1.20 beat Revolution Medicines' score of 1.20 indicating that Halozyme Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Halozyme Therapeutics
9 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Revolution Medicines
10 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Positive

Halozyme Therapeutics has a beta of 0.88, indicating that its stock price is 12% less volatile than the broader market. Comparatively, Revolution Medicines has a beta of 1.4, indicating that its stock price is 40% more volatile than the broader market.

Halozyme Therapeutics has higher revenue and earnings than Revolution Medicines. Revolution Medicines is trading at a lower price-to-earnings ratio than Halozyme Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Halozyme Therapeutics$1.40B8.71$316.89M$3.3532.00
Revolution MedicinesN/AN/A-$1.13B-$8.82N/A

Halozyme Therapeutics has a net margin of 24.86% compared to Revolution Medicines' net margin of 0.00%. Halozyme Therapeutics' return on equity of 260.98% beat Revolution Medicines' return on equity.

Company Net Margins Return on Equity Return on Assets
Halozyme Therapeutics24.86% 260.98% 23.91%
Revolution Medicines N/A -88.20%-57.85%

Summary

Halozyme Therapeutics beats Revolution Medicines on 9 of the 15 factors compared between the two stocks.

How does Halozyme Therapeutics compare to Biogen?

Halozyme Therapeutics (NASDAQ:HALO) and Biogen (NASDAQ:BIIB) are both large-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their earnings, risk, dividends, institutional ownership, profitability, valuation, analyst recommendations and media sentiment.

Halozyme Therapeutics has a beta of 0.88, indicating that its stock price is 12% less volatile than the broader market. Comparatively, Biogen has a beta of 0.17, indicating that its stock price is 83% less volatile than the broader market.

In the previous week, Halozyme Therapeutics had 2 more articles in the media than Biogen. MarketBeat recorded 13 mentions for Halozyme Therapeutics and 11 mentions for Biogen. Halozyme Therapeutics' average media sentiment score of 1.20 beat Biogen's score of 1.10 indicating that Halozyme Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Halozyme Therapeutics
9 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Biogen
7 Very Positive mention(s)
2 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

97.8% of Halozyme Therapeutics shares are held by institutional investors. Comparatively, 87.9% of Biogen shares are held by institutional investors. 2.5% of Halozyme Therapeutics shares are held by company insiders. Comparatively, 0.3% of Biogen shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Biogen has higher revenue and earnings than Halozyme Therapeutics. Halozyme Therapeutics is trading at a lower price-to-earnings ratio than Biogen, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Halozyme Therapeutics$1.40B8.71$316.89M$3.3532.00
Biogen$9.89B3.24$1.29B$5.6538.43

Halozyme Therapeutics has a net margin of 24.86% compared to Biogen's net margin of 8.32%. Halozyme Therapeutics' return on equity of 260.98% beat Biogen's return on equity.

Company Net Margins Return on Equity Return on Assets
Halozyme Therapeutics24.86% 260.98% 23.91%
Biogen 8.32%11.18%6.88%

Halozyme Therapeutics currently has a consensus price target of $91.20, suggesting a potential downside of 14.93%. Biogen has a consensus price target of $230.14, suggesting a potential upside of 5.98%. Given Biogen's higher probable upside, analysts plainly believe Biogen is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62
Biogen
1 Sell rating(s)
13 Hold rating(s)
18 Buy rating(s)
1 Strong Buy rating(s)
2.58

Summary

Halozyme Therapeutics beats Biogen on 10 of the 17 factors compared between the two stocks.

How does Halozyme Therapeutics compare to Alnylam Pharmaceuticals?

Halozyme Therapeutics (NASDAQ:HALO) and Alnylam Pharmaceuticals (NASDAQ:ALNY) are both large-cap healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their earnings, valuation, dividends, media sentiment, profitability, institutional ownership, analyst recommendations and risk.

Halozyme Therapeutics has a beta of 0.88, indicating that its share price is 12% less volatile than the broader market. Comparatively, Alnylam Pharmaceuticals has a beta of 0.31, indicating that its share price is 69% less volatile than the broader market.

Halozyme Therapeutics has higher earnings, but lower revenue than Alnylam Pharmaceuticals. Halozyme Therapeutics is trading at a lower price-to-earnings ratio than Alnylam Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Halozyme Therapeutics$1.40B8.71$316.89M$3.3532.00
Alnylam Pharmaceuticals$3.71B8.96$313.75M$5.3846.22

In the previous week, Alnylam Pharmaceuticals had 1 more articles in the media than Halozyme Therapeutics. MarketBeat recorded 14 mentions for Alnylam Pharmaceuticals and 13 mentions for Halozyme Therapeutics. Halozyme Therapeutics' average media sentiment score of 1.20 beat Alnylam Pharmaceuticals' score of 1.12 indicating that Halozyme Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Halozyme Therapeutics
9 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Alnylam Pharmaceuticals
8 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Halozyme Therapeutics presently has a consensus target price of $91.20, suggesting a potential downside of 14.93%. Alnylam Pharmaceuticals has a consensus target price of $376.67, suggesting a potential upside of 51.47%. Given Alnylam Pharmaceuticals' stronger consensus rating and higher probable upside, analysts clearly believe Alnylam Pharmaceuticals is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62
Alnylam Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
17 Buy rating(s)
2 Strong Buy rating(s)
2.88

97.8% of Halozyme Therapeutics shares are held by institutional investors. Comparatively, 93.0% of Alnylam Pharmaceuticals shares are held by institutional investors. 2.5% of Halozyme Therapeutics shares are held by insiders. Comparatively, 0.9% of Alnylam Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Halozyme Therapeutics has a net margin of 24.86% compared to Alnylam Pharmaceuticals' net margin of 15.26%. Halozyme Therapeutics' return on equity of 260.98% beat Alnylam Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Halozyme Therapeutics24.86% 260.98% 23.91%
Alnylam Pharmaceuticals 15.26%84.93%14.30%

Summary

Alnylam Pharmaceuticals beats Halozyme Therapeutics on 9 of the 17 factors compared between the two stocks.

How does Halozyme Therapeutics compare to Insmed?

Insmed (NASDAQ:INSM) and Halozyme Therapeutics (NASDAQ:HALO) are both large-cap healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their dividends, media sentiment, risk, institutional ownership, analyst recommendations, earnings, valuation and profitability.

Insmed currently has a consensus target price of $205.52, indicating a potential upside of 58.81%. Halozyme Therapeutics has a consensus target price of $91.20, indicating a potential downside of 14.93%. Given Insmed's stronger consensus rating and higher probable upside, equities analysts plainly believe Insmed is more favorable than Halozyme Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Insmed
1 Sell rating(s)
0 Hold rating(s)
22 Buy rating(s)
2 Strong Buy rating(s)
3.00
Halozyme Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62

97.8% of Halozyme Therapeutics shares are held by institutional investors. 2.1% of Insmed shares are held by company insiders. Comparatively, 2.5% of Halozyme Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

In the previous week, Halozyme Therapeutics had 2 more articles in the media than Insmed. MarketBeat recorded 13 mentions for Halozyme Therapeutics and 11 mentions for Insmed. Halozyme Therapeutics' average media sentiment score of 1.20 beat Insmed's score of 1.15 indicating that Halozyme Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Insmed
8 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Halozyme Therapeutics
9 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Halozyme Therapeutics has a net margin of 24.86% compared to Insmed's net margin of -76.94%. Halozyme Therapeutics' return on equity of 260.98% beat Insmed's return on equity.

Company Net Margins Return on Equity Return on Assets
Insmed-76.94% -123.94% -44.30%
Halozyme Therapeutics 24.86%260.98%23.91%

Insmed has a beta of 0.82, meaning that its share price is 18% less volatile than the broader market. Comparatively, Halozyme Therapeutics has a beta of 0.88, meaning that its share price is 12% less volatile than the broader market.

Halozyme Therapeutics has higher revenue and earnings than Insmed. Insmed is trading at a lower price-to-earnings ratio than Halozyme Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Insmed$1.14B24.84-$1.28B-$4.11N/A
Halozyme Therapeutics$1.40B8.71$316.89M$3.3532.00

Summary

Halozyme Therapeutics beats Insmed on 12 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding HALO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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HALO vs. The Competition

MetricHalozyme TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$12.14B$3.85B$7.15B$12.72B
Dividend YieldN/A3.63%2.56%11.15%
P/E Ratio32.0014.18274.9525.29
Price / Sales8.711,477.55656.5698.96
Price / Cash22.43106.6877.0451.44
Price / Book255.2415.1210.336.20
Net Income$316.89M-$22.86M$3.50B$358.50M
7 Day Performance-2.71%-4.34%-3.32%-2.35%
1 Month Performance5.31%-0.02%-0.41%-2.77%
1 Year Performance39.40%40.64%19.21%7.63%

Halozyme Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
HALO
Halozyme Therapeutics
3.1791 of 5 stars
$107.20
+0.2%
$91.20
-14.9%
+38.3%$12.14B$1.40B32.00423
NTRA
Natera
2.1538 of 5 stars
$321.96
-1.3%
$319.38
-0.8%
+89.2%$47.03B$2.31BN/A6,140
RVMD
Revolution Medicines
2.9753 of 5 stars
$205.57
-1.1%
$200.74
-2.4%
+340.7%$44.56B$11.58MN/A250
BIIB
Biogen
3.2678 of 5 stars
$216.65
-0.8%
$227.79
+5.1%
+45.9%$32.28B$10.03B38.357,500
ALNY
Alnylam Pharmaceuticals
4.4566 of 5 stars
$240.69
+1.5%
$386.14
+60.4%
-46.9%$31.73B$4.80B44.742,770

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This page (NASDAQ:HALO) was last updated on 9/12/2026 by MarketBeat.com Staff.
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