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OPKO Health (OPK) Short Interest Ratio & Short Volume

OPKO Health logo
$1.23 +0.08 (+6.96%)
Closing price 04:00 PM Eastern
Extended Trading
$1.20 -0.02 (-2.03%)
As of 07:49 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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OPKO Health Short Interest Overview

As of April 30, 2026, OPKO Health (OPK) had a short interest of 33.76 million shares sold short, representing 8.89% of the public float. This marks a 2.38% increase in short interest since the prior report. The short interest ratio (days to cover) is 12.7, meaning it would take 12.7 days of the average trading volume of 2.37 million shares to cover all short positions.

Current Short Interest
33,763,628 shares
Previous Short Interest
32,978,308 shares
Change Vs. Previous Month
2.38%
Dollar Volume Sold Short
$37.98 million
Short Interest Ratio
12.7 Days to Cover
Last Record Date
April 30, 2026
Outstanding Shares
755,090,000 shares
Short Percent of Float
8.89%
Today's Trading Volume
2,880,185 shares
Average Trading Volume
2,373,625 shares
Today's Volume Vs. Average
121%
Short Selling OPKO Health?
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Short Interest ChartDays to Cover ChartShort Percent of Float Chart

OPK Short Interest Over Time

OPK Days to Cover Over Time

OPK Percentage of Float Shorted Over Time

OPKO Health Tesla Short Interest History & Recent Changes

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Report DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date
4/30/202633,763,628 shares $37.98 million +2.4%8.9%12.69 $1.13
4/15/202632,978,308 shares $38.91 million -1.9%8.6%17.69 $1.18
3/31/202633,615,361 shares $38.32 million +2.6%8.8%10.91 $1.14
3/13/202632,776,490 shares $39.00 million +4.5%8.6%14.38 $1.19
2/27/202631,374,396 shares $37.65 million -1.0%8.2%17.73 $1.20
2/13/202631,677,429 shares $38.96 million +2.6%8.2%10.95 $1.23
1/30/202630,881,465 shares $38.91 million +1.2%8.0%8.38 $1.26
1/15/202630,515,491 shares $39.06 million +0.6%7.9%9.75 $1.28
12/31/202530,340,574 shares $38.23 million -6.9%7.9%7.16 $1.26
12/15/202532,577,197 shares $43.98 million +3.7%8.4%10.82 $1.35
11/28/202531,424,789 shares $41.95 million -7.1%8.1%10.96 $1.34
11/14/202533,814,574 shares $43.28 million +3.2%8.5%12.43 $1.28
10/31/202532,755,482 shares $44.55 million -1.9%8.2%17.94 $1.36
10/15/202533,370,000 shares $50.72 million -0.9%9.4%14.4 $1.52
9/30/202533,680,000 shares $52.20 million +2.4%9.5%13.5 $1.55
9/15/202532,890,000 shares $45.39 million +1.3%9.2%12.5 $1.38
8/31/202532,470,000 shares $44.81 million -1.7%9.1%11.6 $1.38
8/15/202533,040,000 shares $45.26 million +0.8%9.2%11.3 $1.37
7/31/202532,770,000 shares $41.95 million +1.1%9.4%10.5 $1.28
7/15/202532,410,000 shares $43.11 million -5.1%9.3%10.2 $1.33
6/30/202534,140,000 shares $45.06 million +10.1%9.8%10.2 $1.32
6/15/202531,000,000 shares $41.23 million -2.1%8.9%9 $1.33
5/31/202531,660,000 shares $43.53 million -7.0%9.0%9.2 $1.38
5/15/202534,040,000 shares $45.27 million -2.4%9.7%6.6 $1.33
4/30/202534,890,000 shares $48.15 million -0.2%9.7%7 $1.38
4/15/202534,960,000 shares $50.34 million -70.0%11.5%7.1 $1.44
3/31/2025116,490,000 shares $193.37 million +5.0%38.3%23.8 $1.66
3/15/2025111,000,000 shares $193.14 million +24.1%36.6%23.9 $1.74
2/28/202589,470,000 shares $155.68 million +1.0%29.5%18.9 $1.74
2/15/202588,630,000 shares $145.35 million 0.0%28.7%26.5 $1.64
1/31/202588,640,000 shares $134.73 million +0.8%28.7%22.7 $1.52
1/15/202587,920,000 shares $129.24 million -3.7%28.5%22.7 $1.47
12/31/202491,330,000 shares $134.26 million +7.7%29.5%23.6 $1.47
12/15/202484,800,000 shares $134.83 million -14.0%27.4%21.5 $1.59
11/30/202498,570,000 shares $151.80 million +3.1%31.0%25.2 $1.54
11/15/202495,640,000 shares $156.85 million -0.2%30.1%25.9 $1.64
10/31/202495,860,000 shares $144.75 million +3.1%30.1%29.6 $1.51
10/15/202492,940,000 shares $136.62 million -5.5%28.5%30.4 $1.47
9/30/202498,370,000 shares $146.57 million +0.1%30.2%29.2 $1.49
9/15/202498,230,000 shares $154.22 million +0.8%30.1%29.7 $1.57
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8/31/202497,500,000 shares $163.80 million +7.5%29.9%30.5 $1.68
8/15/202490,680,000 shares $143.27 million +3.9%27.9%26.8 $1.58
7/31/202487,310,000 shares $123.98 million +4.5%26.8%25.8 $1.42
7/15/202483,590,000 shares $119.53 million -0.9%25.5%23 $1.43
6/30/202484,310,000 shares $105.39 million -3.6%25.7%21.8 $1.25
6/15/202487,480,000 shares $109.35 million +0.9%26.7%15.2 $1.25
5/31/202486,700,000 shares $118.78 million +1.7%26.5%12.5 $1.37
5/15/202485,230,000 shares $115.06 million -1.6%26.0%11.1 $1.35
4/30/202486,570,000 shares $105.62 million +10.9%26.4%10.2 $1.22
4/15/202478,030,000 shares $95.98 million -16.6%23.8%8.6 $1.23
3/31/202493,610,000 shares $112.33 million -8.4%28.6%6.7 $1.20
3/15/2024102,160,000 shares $91.41 million +3.1%31.2%7.3 $0.89
2/29/202499,060,000 shares $99.06 million +1.1%27.1%8.3 $1.00
2/15/202497,940,000 shares $99.90 million +0.9%26.7%9 $1.02
1/31/202497,070,000 shares $99.01 million -1.6%23.7%9.6 $1.02
1/15/202498,610,000 shares $96.44 million +265.5%24.1%11.3 $0.98
12/31/202326,980,000 shares $40.74 million -4.3%6.5%3.7 $1.51
12/15/202328,180,000 shares $43.54 million -2.2%6.8%14 $1.55
11/30/202328,800,000 shares $42.05 million -1.1%6.9%14.5 $1.46
11/15/202329,130,000 shares $41.36 million -2.6%7.0%14 $1.42
10/31/202329,920,000 shares $37.40 million -6.2%7.2%13.7 $1.25
10/15/202331,910,000 shares $43.08 million -1.7%7.7%13.4 $1.35
9/30/202332,470,000 shares $51.95 million -3.9%7.8%12.9 $1.60
9/15/202333,800,000 shares $55.43 million -1.8%8.1%9.3 $1.64
8/31/202334,410,000 shares $62.97 million +2.4%8.3%9.1 $1.83
8/15/202333,620,000 shares $61.19 million -0.7%8.1%8.8 $1.82
7/31/202333,870,000 shares $63.00 million -7.2%8.1%8.9 $1.86
7/15/202336,510,000 shares $76.31 million -6.2%8.8%9.9 $2.09
6/30/202338,930,000 shares $84.48 million -2.4%9.4%10.9 $2.17
6/15/202339,880,000 shares $60.62 million -3.5%9.6%15.6 $1.52
5/31/202341,340,000 shares $57.46 million +1.2%9.9%15.1 $1.39
5/15/202340,870,000 shares $70.30 million +1.9%9.8%12.9 $1.72
4/30/202340,120,000 shares $58.98 million +2.8%9.6%13 $1.47
4/15/202339,030,000 shares $60.50 million -3.3%9.4%12.3 $1.55
3/31/202340,360,000 shares $58.93 million +2.9%9.7%12.6 $1.46
3/15/202339,210,000 shares $53.33 million +4.2%9.4%12.2 $1.36
2/28/202337,620,000 shares $42.89 million +7.7%9.0%13.1 $1.14
2/15/202334,930,000 shares $42.27 million -3.6%8.4%13.3 $1.21
1/31/202336,250,000 shares $46.76 million -3.2%8.7%14 $1.29
1/15/202337,440,000 shares $58.78 million -2.5%9.1%15.1 $1.57
12/30/202238,400,000 shares $48 million +4.4%9.3%16.6 $1.25
12/15/202236,770,000 shares $45.96 million -3.5%8.9%16.2 $1.25
11/30/202238,110,000 shares $57.17 million +2.2%9.2%16.9 $1.50
11/15/202237,300,000 shares $65.65 million -0.4%9.0%16.5 $1.76
10/31/202237,450,000 shares $71.16 million +0.0%9.1%15.6 $1.90
10/15/202237,440,000 shares $64.77 million +0.2%9.1%13.8 $1.73
9/30/202237,360,000 shares $70.61 million -2.1%9.0%13.6 $1.89
9/15/202238,150,000 shares $78.59 million -2.3%9.2%13.4 $2.06
8/31/202239,030,000 shares $85.09 million -11.5%10.6%10.1 $2.18
8/15/202244,090,000 shares $115.07 million -11.2%12.0%10.7 $2.61
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7/31/202249,640,000 shares $117.15 million +2.0%15.3%11 $2.36
7/15/202248,680,000 shares $134.36 million +1.8%15.0%10.8 $2.76
6/30/202247,810,000 shares $120.96 million -11.8%13.1%10.2 $2.53
6/15/202254,230,000 shares $136.66 million +10.4%13.4%11.3 $2.52
5/31/202249,110,000 shares $147.33 million +2.7%12.1%11.5 $3.00
5/15/202247,840,000 shares $144.96 million +1.9%11.7%11 $3.03
4/30/202246,940,000 shares $126.74 million +4.5%11.4%11.4 $2.70
4/15/202244,930,000 shares $150.07 million -1.5%10.9%9.9 $3.34
3/31/202245,610,000 shares $156.90 million +5.7%11.1%9.3 $3.44
3/15/202243,150,000 shares $143.26 million -6.8%10.5%8.1 $3.32
2/28/202246,320,000 shares $144.98 million +7.4%11.2%8.5 $3.13
2/15/202243,150,000 shares $141.96 million +0.1%10.4%7.8 $3.29
1/31/202243,130,000 shares $135.00 million -1.5%10.4%8 $3.13
1/15/202243,780,000 shares $198.32 million -12.7%10.6%8.5 $4.53
12/31/202150,120,000 shares $241.08 million +1.9%12.1%11.7 $4.81
12/15/202149,210,000 shares $200.78 million 0.0%11.9%12.2 $4.08
11/30/202149,220,000 shares $193.43 million +3.3%11.9%14.7 $3.93
11/15/202147,630,000 shares $192.43 million -1.2%11.5%15.6 $4.04
10/29/202148,200,000 shares $182.68 million -0.2%11.7%16.1 $3.79
10/15/202148,290,000 shares $179.64 million -1.2%11.7%15.7 $3.72
9/30/202148,890,000 shares $178.45 million -2.5%11.8%14.4 $3.65
9/15/202150,160,000 shares $187.60 million -2.5%12.1%12.9 $3.74
8/31/202151,420,000 shares $198.48 million -5.8%12.6%12.8 $3.86
8/13/202154,600,000 shares $200.93 million +1.0%13.3%13 $3.68
7/30/202154,070,000 shares $186.00 million +0.5%13.2%12 $3.44
7/15/202153,800,000 shares $190.45 million -0.6%13.4%11.9 $3.54
6/30/202154,130,000 shares $219.23 million -5.2%13.4%11.8 $4.05
6/15/202157,100,000 shares $210.70 million -1.5%14.2%12.8 $3.69
5/28/202157,960,000 shares $221.41 million -27.2%14.4%12.2 $3.82

OPK Short Interest - Frequently Asked Questions

Short interest is the volume of OPKO Health shares that have been sold short but have not yet been covered or closed out. As of April 30th, investors have sold 33,763,628 shares of OPK short. 8.89% of OPKO Health's shares are currently sold short. Learn More on OPKO Health's current short interest.

The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. OPK shares currently have a short interest ratio of 12.7. Learn More on OPKO Health's short interest ratio.

Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 8.89% of OPKO Health's floating shares are currently sold short.

OPKO Health saw a increase in short interest during the month of April. As of April 30th, there was short interest totaling 33,763,628 shares, an increase of 2.4% from the previous total of 32,978,308 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment.

8.89% of OPKO Health's shares are currently sold short. Here is how the short interest of companies in the industry of "biotechnology" compare to OPKO Health: Celldex Therapeutics, Inc. (10.21%), BioCryst Pharmaceuticals, Inc. (15.51%), Innoviva, Inc. (8.66%), Novavax, Inc. (30.39%), Zenas BioPharma, Inc. (24.25%), MannKind Corporation (9.88%), Geron Corporation (12.00%), Lexicon Pharmaceuticals, Inc. (6.25%), Ironwood Pharmaceuticals, Inc. (11.67%), Crescent Biopharma, Inc. (9.52%),

As of the most recent reporting period, the following stocks had the largest short interest positions: SPDR S&P 500 ETF Trust ($86.09 billion), Invesco QQQ ($39.89 billion), iShares Russell 2000 ETF ($26.13 billion), Western Digital Corporation ($12.66 billion), Salesforce Inc. ($12.29 billion), Sandisk Corporation ($11.87 billion), SPDR S&P Biotech ETF ($9.82 billion), Lumentum Holdings Inc. ($8.51 billion), iShares 20+ Year Treasury Bond ETF ($7.76 billion), and Bloom Energy Corporation ($7.40 billion). View all of the most shorted stocks.

Short selling OPK is an investing strategy that aims to generate trading profit from OPKO Health as its price is falling. OPK shares are trading up $0.04 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit.

A short squeeze for OPKO Health occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of OPK, which in turn drives the price of the stock up even further.

Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including OPK, twice per month. The most recent reporting period available is April, 30 2026.

Understanding short interest metrics can help you assess how traders are positioning around a stock like OPK:

  • Shares Sold Short: The total number of shares that have been sold by short sellers but have not yet been covered or closed out. A high number may indicate bearish sentiment.
  • Short Float: The percentage of a company’s publicly available shares (or "float") that are sold short. A higher short float suggests a greater portion of the stock is being bet against.
  • Days to Cover (Short Interest Ratio): This estimates how many days it would take short sellers to cover their positions, based on average daily trading volume. Higher values can signal potential for a short squeeze if buying pressure increases.

These metrics are often used by traders to gauge sentiment, volatility risk, and the potential for price movements based on short covering activity.


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This page (NASDAQ:OPK) was last updated on 5/20/2026 by MarketBeat.com Staff.
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