NASDAQ:SHPH Shuttle Pharmaceuticals (SHPH) Stock Price, News & Analysis $3.50 -0.15 (-4.11%) Closing price 08/1/2025 04:00 PM EasternExtended Trading$3.53 +0.03 (+0.86%) As of 08/1/2025 07:43 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Shuttle Pharmaceuticals Stock (NASDAQ:SHPH) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get SHPH alerts:Sign Up Key Stats Today's Range$3.33▼$3.7050-Day Range$3.26▼$5.5952-Week Range$3.00▼$82.50Volume29,879 shsAverage Volume168,865 shsMarket Capitalization$1.54 millionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingN/A Company Overview Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. It develops Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas SP-1-161, an HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway for radiation sensitizing cancer cells and protecting normal cells; SP-2-225, a pre-clinical class IIb that effects on the regulation of the immune system; and SP-1-303, a pre-clinical selective Class I HDAC for the treatment of ER positive cancers . The company is based in Gaithersburg, Maryland. Read More Shuttle Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks16th Percentile Overall ScoreSHPH MarketRank™: Shuttle Pharmaceuticals scored higher than 16% of companies evaluated by MarketBeat. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's OpinionN/AAnalyst RatingN/A Consensus RatingThere is not enough analysis data for Shuttle Pharmaceuticals. Earnings and Valuation0.6 / 5Proj. Earnings GrowthN/A Price to Earnings Ratio vs. the MarketThe P/E ratio of Shuttle Pharmaceuticals is -0.84, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Shuttle Pharmaceuticals is -0.84, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioShuttle Pharmaceuticals has a P/B Ratio of 0.80. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.Read more about Shuttle Pharmaceuticals' valuation and earnings. Short Interest5.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted4.03% of the float of Shuttle Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverShuttle Pharmaceuticals has a short interest ratio ("days to cover") of 0.1, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Shuttle Pharmaceuticals has recently decreased by 12.47%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldShuttle Pharmaceuticals does not currently pay a dividend.Dividend GrowthShuttle Pharmaceuticals does not have a long track record of dividend growth. Sustainability and ESGN/AEnvironmental ScoreN/A Percentage of Shares Shorted4.03% of the float of Shuttle Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverShuttle Pharmaceuticals has a short interest ratio ("days to cover") of 0.1, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Shuttle Pharmaceuticals has recently decreased by 12.47%, indicating that investor sentiment is improving significantly. News and Social Media0.5 / 5News SentimentN/A News SentimentShuttle Pharmaceuticals has a news sentiment score of -1.08. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.45 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 1 news article for Shuttle Pharmaceuticals this week, compared to 1 article on an average week.MarketBeat FollowsOnly 1 people have added Shuttle Pharmaceuticals to their MarketBeat watchlist in the last 30 days. This is a decrease of -50% compared to the previous 30 days. Company Ownership0.8 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Shuttle Pharmaceuticals insiders have not sold or bought any company stock.Percentage Held by Insiders12.60% of the stock of Shuttle Pharmaceuticals is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by InstitutionsOnly 4.58% of the stock of Shuttle Pharmaceuticals is held by institutions.Read more about Shuttle Pharmaceuticals' insider trading history. Receive SHPH Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Shuttle Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. Email Address SHPH Stock News HeadlinesShuttle Pharmaceuticals COO Resigns Amid Leadership ChangesJuly 30, 2025 | tipranks.comShuttle Pharmaceuticals Inc News (SHPH) - Investing.comJuly 2, 2025 | investing.comMusk’s Project Colossus could mint millionairesI predict this single breakthrough could make Elon the world’s first trillionaire — and mint more new millionaires than any tech advance in history. And for a limited time, you have the chance to claim a stake in this project, even though it’s housed inside Elon’s private company, xAI. | Brownstone Research (Ad)SHPH - Shuttle Pharmaceuticals Holdings Inc Key Metrics | MorningstarJune 28, 2025 | morningstar.comMShuttle Pharmaceuticals Announces Closing of $4.25 Million Private Placement Priced At-the-Market - MorningstarJune 26, 2025 | morningstar.comMSHPH - Shuttle Pharmaceuticals Holdings Inc News | MorningstarJune 26, 2025 | morningstar.comMShuttle Pharmaceuticals Secures $4.25M in Private PlacementJune 26, 2025 | msn.comShuttle Pharmaceuticals Announces Closing of $4.25 Million Private Placement Priced At-the-MarketJune 24, 2025 | globenewswire.comSee More Headlines SHPH Stock Analysis - Frequently Asked Questions How have SHPH shares performed this year? Shuttle Pharmaceuticals' stock was trading at $21.4750 at the start of the year. Since then, SHPH stock has decreased by 83.7% and is now trading at $3.50. How were Shuttle Pharmaceuticals' earnings last quarter? Shuttle Pharmaceuticals Holdings, Inc. (NASDAQ:SHPH) announced its earnings results on Thursday, May, 8th. The company reported ($7.50) earnings per share for the quarter. When did Shuttle Pharmaceuticals' stock split? Shuttle Pharmaceuticals shares reverse split before market open on Monday, June 16th 2025.The 1-25 reverse split was announced on Thursday, June 12th 2025. The number of shares owned by shareholders was adjusted after the market closes on Friday, June 13th 2025. An investor that had 100 shares of stock prior to the reverse split would have 4 shares after the split. When did Shuttle Pharmaceuticals IPO? Shuttle Pharmaceuticals (SHPH) raised $10 million in an IPO on Wednesday, August 31st 2022. The company issued 1,225,888 shares at a price of $8.13 per share. How do I buy shares of Shuttle Pharmaceuticals? Shares of SHPH stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Shuttle Pharmaceuticals own? Based on aggregate information from My MarketBeat watchlists, some other companies that Shuttle Pharmaceuticals investors own include MSP Recovery (LIFW), NIO (NIO), Tesla (TSLA), Broadcom (AVGO), AMTD Digital (HKD) and NVIDIA (NVDA). Company Calendar Last Earnings5/08/2025Today8/02/2025Next Earnings (Estimated)9/02/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - DRUGS Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:SHPH CIK1757499 Webwww.shuttlepharma.com Phone240-403-4212FaxN/AEmployees5Year FoundedN/AProfitability EPS (Trailing Twelve Months)($4.15) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$9.15 million Net MarginsN/A Pretax MarginN/A Return on Equity-1,203.10% Return on Assets-370.42% Debt Debt-to-Equity RatioN/A Current Ratio2.78 Quick Ratio2.78 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$4.35 per share Price / Book0.80Miscellaneous Outstanding Shares440,000Free Float384,000Market Cap$1.54 million OptionableNot Optionable Beta-1.08 Social Links 7 Stocks to Buy And Hold ForeverEnter your email address and we'll send you MarketBeat's list of seven stocks and why their long-term outlooks are very promising. 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