NASDAQ:SHPH Shuttle Pharmaceuticals (SHPH) Stock Price, News & Analysis $0.49 +0.04 (+8.07%) Closing price 04:00 PM EasternExtended Trading$0.47 -0.02 (-4.70%) As of 05:31 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Shuttle Pharmaceuticals Stock (NASDAQ:SHPH) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SHPH alerts:Sign Up Key Stats Today's Range$0.41▼$0.4950-Day Range$0.45▼$1.0552-Week Range$0.38▼$6.19Volume399,709 shsAverage Volume2.24 million shsMarket Capitalization$2.86 millionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingSell Company Overview Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. It develops Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas SP-1-161, an HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway for radiation sensitizing cancer cells and protecting normal cells; SP-2-225, a pre-clinical class IIb that effects on the regulation of the immune system; and SP-1-303, a pre-clinical selective Class I HDAC for the treatment of ER positive cancers . The company is based in Gaithersburg, Maryland. Read More Shuttle Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks26th Percentile Overall ScoreSHPH MarketRank™: Shuttle Pharmaceuticals scored higher than 26% of companies evaluated by MarketBeat. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion0.7 / 5Analyst RatingSell Consensus RatingShuttle Pharmaceuticals has received a consensus rating of Sell. The company's average rating score is 1.00, and is based on no strong buy ratings, no buy ratings, no hold ratings, and 1 sell rating.Amount of Analyst CoverageShuttle Pharmaceuticals has only been the subject of 1 research reports in the past 90 days.Read more about Shuttle Pharmaceuticals' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthN/A Price to Earnings Ratio vs. the MarketThe P/E ratio of Shuttle Pharmaceuticals is -0.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Shuttle Pharmaceuticals is -0.10, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioShuttle Pharmaceuticals has a P/B Ratio of 0.42. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities. Short Interest5.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted4.41% of the float of Shuttle Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverShuttle Pharmaceuticals has a short interest ratio ("days to cover") of 0.81, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Shuttle Pharmaceuticals has recently decreased by 48.86%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldShuttle Pharmaceuticals does not currently pay a dividend.Dividend GrowthShuttle Pharmaceuticals does not have a long track record of dividend growth. News and Social Media3.7 / 5News Sentiment0.96 News SentimentShuttle Pharmaceuticals has a news sentiment score of 0.96. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.76 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 3 news articles for Shuttle Pharmaceuticals this week, compared to 1 article on an average week.Search InterestOnly 2 people have searched for SHPH on MarketBeat in the last 30 days. This is a decrease of 0% compared to the previous 30 days.MarketBeat Follows4 people have added Shuttle Pharmaceuticals to their MarketBeat watchlist in the last 30 days. Company Ownership0.5 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Shuttle Pharmaceuticals insiders have not sold or bought any company stock.Percentage Held by Insiders12.60% of the stock of Shuttle Pharmaceuticals is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by Institutions4.58% of the stock of Shuttle Pharmaceuticals is held by institutions.Read more about Shuttle Pharmaceuticals' insider trading history. Receive SHPH Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Shuttle Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. 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That's larger than Tesla, xAI, Starlink, X, Neuralink, and SpaceX combined.June 10 at 1:00 AM | Banyan Hill Publishing (Ad)E.F. Hutton & Co. Serves as Exclusive M&A Advisor and Placement Agent on Completed Shuttle Pharmaceuticals–United Dogecoin Merger to Create the Largest Public Dogecoin MinerMay 7, 2026 | globenewswire.comShuttle to Acquire United Dogecoin in Push to Build Public DOGE Mining PlatformMay 2, 2026 | finance.yahoo.comWhy is SHPH stock soaring today? Dogecoin mining pivot sparks rallyMay 2, 2026 | msn.comE.F. Hutton & Co. Serves as Exclusive Placement Agent on Shuttle Pharmaceuticals’ $3.5 Million Public OfferingMarch 12, 2026 | markets.businessinsider.comE.F. Hutton & Co. Serves as Exclusive Placement Agent on Shuttle Pharmaceuticals' $3.5 Million Public OfferingMarch 12, 2026 | globenewswire.comSee More Headlines SHPH Stock Analysis - Frequently Asked Questions How have SHPH shares performed this year? Shuttle Pharmaceuticals' stock was trading at $1.80 at the beginning of the year. Since then, SHPH stock has decreased by 74.1% and is now trading at $0.4670. How were Shuttle Pharmaceuticals' earnings last quarter? Shuttle Pharmaceuticals Holdings, Inc. (NASDAQ:SHPH) posted its quarterly earnings data on Friday, May, 15th. The company reported ($0.43) EPS for the quarter. When did Shuttle Pharmaceuticals' stock split? Shuttle Pharmaceuticals shares reverse split before market open on Thursday, June 11th 2026.The 1-10 reverse split was announced on Tuesday, June 9th 2026. The number of shares owned by shareholders will be adjusted after the closing bell on Wednesday, June 10th 2026. An investor that had 100 shares of stock prior to the reverse split would have 10 shares after the split. When did Shuttle Pharmaceuticals IPO? Shuttle Pharmaceuticals (SHPH) raised $10 million in an initial public offering (IPO) on Tuesday, August 30th 2022. The company issued 1,225,888 shares at a price of $8.13 per share. How do I buy shares of Shuttle Pharmaceuticals? Shares of SHPH stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Shuttle Pharmaceuticals own? Based on aggregate information from My MarketBeat watchlists, some other companies that Shuttle Pharmaceuticals investors own include MSP Recovery (LIFW), NIO (NIO), Tesla (TSLA), Broadcom (AVGO), AMTD Digital (HKD) and NVIDIA (NVDA). Company Calendar Last Earnings5/15/2026Today6/10/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Yellow Zone (2w+) 1-Year History Jun 25 Sep 25 Dec 25 Mar 26 Jun 26 For the last 2 weeks, SHPH's financial health has been in the Yellow zone, according to TradeSmith. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - DRUGS Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:SHPH CIK1757499 Webwww.shuttlepharma.com Phone240-403-4212FaxN/AEmployees5Year Founded2012Profitability EPS (Trailing Twelve Months)($4.77) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$11.72 million Net MarginsN/A Pretax MarginN/A Return on Equity-408.34% Return on Assets-138.15% Debt Debt-to-Equity RatioN/A Current Ratio0.30 Quick Ratio0.30 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$1.11 per share Price / Book0.44Miscellaneous Outstanding Shares5,850,000Free Float5,114,000Market Cap$2.86 million OptionableNot Optionable Beta0.18 Social Links 10 Stocks Powering The Next AI Boom The AI boom is creating opportunities across semiconductors, cloud computing, enterprise software, infrastructure, cybersecurity, and automation. Inside this report, you’ll find 10 companies positioned to benefit as artificial intelligence moves from hype to real-world deployment and becomes a core growth driver for corporate America.Get This Free Report This page (NASDAQ:SHPH) was last updated on 6/10/2026 by MarketBeat.com Staff. From Our PartnersHe Called NVIDIA at $1.10 – Now He Says, “SELL”The analyst who called NVIDIA at $1.10 now says sell. According to Alexander Green, Chief Investment Strategis...The Oxford Club | SponsoredTrump Takes Emergency Action - Plus Elon Musk's New VentureElon Musk has quietly launched a new venture - one that has nothing to do with rockets, EVs, or Neuralink. 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