NASDAQ:SHPH Shuttle Pharmaceuticals (SHPH) Stock Price, News & Analysis $0.22 -0.01 (-2.79%) Closing price 05/16/2025 04:00 PM EasternExtended Trading$0.21 -0.01 (-2.78%) As of 05/16/2025 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Shuttle Pharmaceuticals Stock (NASDAQ:SHPH) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get SHPH alerts:Sign Up Key Stats Today's Range$0.20▼$0.2250-Day Range$0.21▼$0.4552-Week Range$0.20▼$4.71Volume1.54 million shsAverage Volume1.55 million shsMarket Capitalization$1.35 millionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingN/A Company OverviewShuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. It develops Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas SP-1-161, an HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway for radiation sensitizing cancer cells and protecting normal cells; SP-2-225, a pre-clinical class IIb that effects on the regulation of the immune system; and SP-1-303, a pre-clinical selective Class I HDAC for the treatment of ER positive cancers . The company is based in Gaithersburg, Maryland.Read More… Shuttle Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks5th Percentile Overall ScoreSHPH MarketRank™: Shuttle Pharmaceuticals scored higher than 5% of companies evaluated by MarketBeat. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's OpinionN/AAnalyst RatingN/A Consensus RatingThere is not enough analysis data for Shuttle Pharmaceuticals. Earnings and Valuation0.6 / 5Proj. Earnings GrowthN/A Price to Earnings Ratio vs. the MarketThe P/E ratio of Shuttle Pharmaceuticals is -0.05, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Shuttle Pharmaceuticals is -0.05, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioShuttle Pharmaceuticals has a P/B Ratio of 0.11. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted21.28% of the float of Shuttle Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverShuttle Pharmaceuticals has a short interest ratio ("days to cover") of 1.1, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Shuttle Pharmaceuticals has recently increased by 961.04%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldShuttle Pharmaceuticals does not currently pay a dividend.Dividend GrowthShuttle Pharmaceuticals does not have a long track record of dividend growth. Sustainability and ESGN/AEnvironmental ScoreN/A Percentage of Shares Shorted21.28% of the float of Shuttle Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverShuttle Pharmaceuticals has a short interest ratio ("days to cover") of 1.1, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Shuttle Pharmaceuticals has recently increased by 961.04%, indicating that investor sentiment is decreasing significantly. News and Social Media1.1 / 5News Sentiment0.00 News Coverage This WeekMarketBeat has tracked 2 news articles for Shuttle Pharmaceuticals this week, compared to 1 article on an average week.Search Interest5 people have searched for SHPH on MarketBeat in the last 30 days. This is an increase of 150% compared to the previous 30 days.MarketBeat Follows7 people have added Shuttle Pharmaceuticals to their MarketBeat watchlist in the last 30 days. This is an increase of 133% compared to the previous 30 days. Company Ownership0.8 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Shuttle Pharmaceuticals insiders have not sold or bought any company stock.Percentage Held by Insiders12.60% of the stock of Shuttle Pharmaceuticals is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by InstitutionsOnly 4.58% of the stock of Shuttle Pharmaceuticals is held by institutions.Read more about Shuttle Pharmaceuticals' insider trading history. Receive SHPH Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Shuttle Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. Email Address SHPH Stock News HeadlinesShuttle Pharmaceuticals Holdings, Inc.: Shuttle Pharma Provides Corporate UpdateMay 16 at 8:44 PM | finanznachrichten.deShuttle Pharma Provides Corporate UpdateMay 15 at 4:45 PM | globenewswire.comSecure this "AI Fuel" Stock Before the Billionaires Buy It AllThe Washington Post says America is running out of a key material needed for AI—and without it, companies like NVIDIA could be forced to shut down. While billionaires like Buffett and Gates scramble to secure access, one under-the-radar firm has quietly locked up supply. Bloomberg even calls it a “monopoly.” And it’s still trading near $20.May 18, 2025 | Behind the Markets (Ad)Shuttle Pharma FDA Orphan-Drug Nears Patient Enrollment Milestone for Phase 2 Clinical TrialMay 8, 2025 | globenewswire.comShuttle Pharmaceuticals to Present Phase 2 Trial Update at Planet MicroCap Showcase: VEGAS 2025April 24, 2025 | nasdaq.comShuttle Pharma to Present at the Planet MicroCap Showcase: VEGAS 2025 on April 23, 2025April 21, 2025 | globenewswire.comShuttle Pharmaceuticals files provisional patent application with USPTOApril 12, 2025 | markets.businessinsider.comShuttle Pharma Developing Pretreatment Diagnostic Blood Tests for Prostate Cancer, Files Provisional Patent for PSMA Ligand Conjugates to Treat Prostate CancerApril 10, 2025 | globenewswire.comSee More Headlines SHPH Stock Analysis - Frequently Asked Questions How have SHPH shares performed this year? Shuttle Pharmaceuticals' stock was trading at $0.8590 at the beginning of 2025. Since then, SHPH stock has decreased by 74.9% and is now trading at $0.2160. View the best growth stocks for 2025 here. How were Shuttle Pharmaceuticals' earnings last quarter? Shuttle Pharmaceuticals Holdings, Inc. (NASDAQ:SHPH) posted its earnings results on Thursday, May, 8th. The company reported ($0.30) EPS for the quarter. When did Shuttle Pharmaceuticals IPO? Shuttle Pharmaceuticals (SHPH) raised $10 million in an initial public offering on Wednesday, August 31st 2022. The company issued 1,225,888 shares at a price of $8.13 per share. Who are Shuttle Pharmaceuticals' major shareholders? Top institutional shareholders of Shuttle Pharmaceuticals include Armistice Capital LLC (1.12%). Insiders that own company stock include Bette Jacobs, Peter Dritschilo and Hoek Michael Vander. View institutional ownership trends. How do I buy shares of Shuttle Pharmaceuticals? Shares of SHPH stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Shuttle Pharmaceuticals own? Based on aggregate information from My MarketBeat watchlists, some other companies that Shuttle Pharmaceuticals investors own include Mullen Automotive (MULN), MSP Recovery (LIFW), MSP Recovery (LIFW), NIO (NIO), Tesla (TSLA), Broadcom (AVGO) and AMTD Digital (HKD). Company Calendar Last Earnings5/08/2025Today5/17/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry Pharmaceutical preparations Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:SHPH CIK1757499 Webwww.shuttlepharma.com Phone240-403-4212FaxN/AEmployees5Year FoundedN/AProfitability EPS (Most Recent Fiscal Year)($4.15) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income$-6,590,000.00 Net MarginsN/A Pretax MarginN/A Return on Equity-583.02% Return on Assets-258.92% Debt Debt-to-Equity RatioN/A Current Ratio0.22 Quick Ratio0.22 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$2.03 per share Price / Book0.11Miscellaneous Outstanding Shares6,258,000Free Float2,463,000Market Cap$1.35 million OptionableNot Optionable Beta-0.93 7 AI Stocks to Invest in Today: Capitalizing on AI and Tech Trends in 2025Discover the top 7 AI stocks to invest in right now. This exclusive report highlights the companies leading the AI revolution and shaping the future of technology in 2025.Get This Free Report This page (NASDAQ:SHPH) was last updated on 5/18/2025 by MarketBeat.com Staff From Our PartnersThis Signal Only Flashes Once Every 4 Years – And It Just TriggeredThis same signal has appeared twice before in the past 8 years — both times, it kicked off major moves in cryp...Crypto Swap Profits | SponsoredMarket Panic: Trump Just Dropped a Bomb on Your Stockstock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tarif...American Alternative | SponsoredGet Your Bank Account “Fed Invasion” Ready with THESE 4 Simple StepsStarting as soon as a few months from now, the United States government will make a sweeping change to bank ac...Weiss Ratings | SponsoredMusk’s AI Masterplan – Our #1 AI Stock to Buy NowMusk has launched a bold new AI initiative—and while you can’t invest in it directly, one overlooked stock cou...Behind the Markets | Sponsored🚨 Nvidia Just Inked a $7B AI Deal—This Could Change EverythingOn Wednesday, Nvidia stock surged—again. 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