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Soleno Therapeutics (SLNO) Institutional Ownership

Current Institutional Ownership Percentage: 97.42%
Number of Institutional Buyers (last 12 months): 188
Total Institutional Inflows (last 12 months): $1.45B

Number of Institutional Sellers (last 12 months): 79
Total Institutional Outflows (last 12 months): $937.25M

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SLNO Institutional Buying and Selling by Quarter

Soleno Therapeutics Major Shareholders & Ownership History

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Reporting Date	Major Shareholder Name	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
5/26/2026	Glenmede Trust Co. NA	8,229	$276K	0.0%	+5.6%	0.016%
5/20/2026	Vivo Capital LLC	294,909	$9.87M	0.8%	-67.0%	0.566%
5/19/2026	Bank of America Corp DE	439,902	$14.73M	0.0%	+110.9%	0.844%
5/19/2026	Anson Funds Management LP	44,231	$1.48M	0.1%	N/A	0.085%
5/19/2026	Janus Henderson Group PLC	7,099,328	$237.63M	0.1%	-1.1%	13.621%
5/18/2026	ADAR1 Capital Management LLC	46,830	$1.57M	0.1%	+12.0%	0.090%
5/18/2026	California State Teachers Retirement System	58,388	$1.96M	0.0%	+43.4%	0.112%
5/18/2026	Readystate Asset Management LP	952,165	$31.88M	1.4%	+8.9%	1.827%
5/18/2026	Royal Bank of Canada	4,659	$155K	0.0%	-51.8%	0.009%
5/18/2026	Rock Springs Capital Management LP	257,253	$8.61M	0.5%	+4.1%	0.494%
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5/18/2026	Exome Asset Management LLC	61,673	$2.07M	1.1%	-968.6%	0.118%
5/16/2026	The Manufacturers Life Insurance Company	22,878	$766K	0.0%	-44.5%	0.044%
5/16/2026	SummitTX Capital L.P.	56,585	$1.89M	0.1%	-73.3%	0.109%
5/16/2026	Lazard Asset Management LLC	32,664	$1.09M	0.0%	-32.6%	0.063%
5/15/2026	Commodore Capital LP	652,432	$21.84M	1.3%	-45.6%	1.252%
5/15/2026	Weiss Asset Management LP	23,000	$770K	0.0%	N/A	0.044%
5/15/2026	Rice Hall James & Associates LLC	206,147	$6.90M	0.4%	N/A	0.396%
5/15/2026	Granahan Investment Management LLC	114,825	$3.84M	0.2%	-16.5%	0.220%
5/14/2026	Renaissance Technologies LLC	447,300	$14.98M	0.0%	N/A	0.858%
5/14/2026	Pale Fire Capital SE	8,450	$283K	0.0%	N/A	0.016%
5/14/2026	GC Wealth Management RIA LLC	20,027	$671K	0.0%	N/A	0.038%
5/14/2026	Sei Investments Co.	62,946	$2.11M	0.0%	-6.5%	0.121%
5/7/2026	SEB Asset Management AB	187,475	$6.28M	0.0%	N/A	0.360%
5/7/2026	Swiss National Bank	90,300	$3.02M	0.0%	+1.3%	0.173%
5/5/2026	Bank of New York Mellon Corp	277,851	$9.30M	0.0%	-55.3%	0.538%
5/4/2026	Emerald Mutual Fund Advisers Trust	200,727	$6.72M	0.3%	-13.7%	0.389%
5/4/2026	Emerald Advisers LLC	274,138	$9.18M	0.3%	-33.6%	0.531%
5/1/2026	Candriam S.C.A.	281,620	$9.43M	0.0%	N/A	0.546%
4/30/2026	Hsbc Holdings PLC	174,204	$5.83M	0.0%	N/A	0.337%
4/27/2026	Y Intercept Hong Kong Ltd	47,731	$1.60M	0.0%	+78.9%	0.092%
4/22/2026	Pictet Asset Management Holding SA	616,217	$20.63M	0.0%	-1.3%	1.194%
4/16/2026	SG Americas Securities LLC	19,139	$641K	0.0%	-52.4%	0.037%
3/16/2026	Avoro Capital Advisors LLC	2,900,000	$134.27M	1.3%	+12.5%	5.618%
3/3/2026	Caitong International Asset Management Co. Ltd	822	$38K	0.0%	N/A	0.002%
2/26/2026	Seven Fleet Capital Management LP	130,079	$6.02M	4.6%	N/A	0.242%
2/23/2026	Virtu Financial LLC	22,878	$1.06M	0.0%	N/A	0.043%
2/19/2026	T. Rowe Price Investment Management Inc.	553	$26K	0.0%	-97.8%	0.001%
2/19/2026	Invesco Ltd.	875,019	$40.51M	0.0%	-41.7%	1.629%
2/18/2026	Empowered Funds LLC	1,495	$69K	0.0%	N/A	0.003%
2/18/2026	KVP Capital Advisors LP	59,700	$2.76M	2.7%	N/A	0.111%
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2/18/2026	XTX Topco Ltd	36,294	$1.68M	0.0%	N/A	0.068%
2/18/2026	Virtus Investment Advisers LLC	5,116	$237K	0.1%	+260.5%	0.010%
2/18/2026	Wellington Management Group LLP	3,322,799	$153.85M	0.1%	+43.7%	6.187%
2/18/2026	SummitTX Capital L.P.	211,727	$9.80M	0.3%	+59.4%	0.394%
2/18/2026	Sphera Funds Management LTD.	136,314	$6.31M	1.2%	+227.6%	0.254%
2/18/2026	Readystate Asset Management LP	874,447	$40.49M	1.6%	+324.9%	1.628%
2/18/2026	Oxford Asset Management LLP	15,021	$695K	0.3%	N/A	0.028%
2/18/2026	Man Group plc	15,047	$697K	0.0%	+30.9%	0.028%
2/18/2026	Janus Henderson Group PLC	7,178,354	$332.30M	0.1%	+18.5%	13.365%
2/18/2026	Gotham Asset Management LLC	12,130	$562K	0.0%	N/A	0.023%
2/18/2026	Engineers Gate Manager LP	168,005	$7.78M	0.1%	N/A	0.313%
2/18/2026	Catalio Capital Management LP	360,340	$16.68M	3.1%	-13.8%	0.671%
2/18/2026	Commodore Capital LP	1,200,000	$55.56M	3.7%	-11.1%	2.234%
2/18/2026	Balyasny Asset Management L.P.	227,751	$10.55M	0.0%	-65.5%	0.424%
2/17/2026	Freestone Grove Partners LP	10,258	$475K	0.0%	-79.7%	0.019%
2/17/2026	Guggenheim Capital LLC	18,181	$842K	0.0%	+92.0%	0.034%
2/17/2026	Logos Global Management LP	300,000	$13.89M	0.8%	N/A	0.559%
2/17/2026	ADAR1 Capital Management LLC	41,830	$1.94M	0.1%	+65.8%	0.078%
2/17/2026	AQR Capital Management LLC	58,752	$2.72M	0.0%	+58.4%	0.109%
2/17/2026	Braidwell LP	1,187,859	$55.00M	1.8%	-7.3%	2.212%
2/17/2026	Ally Bridge Group NY LLC	168,029	$7.78M	8.1%	-69.6%	0.313%
2/17/2026	Lazard Asset Management LLC	48,445	$2.24M	0.0%	-14.2%	0.090%
2/17/2026	Trexquant Investment LP	132,912	$6.15M	0.1%	+1,185.9%	0.247%
2/17/2026	Jump Financial LLC	54,487	$2.52M	0.0%	N/A	0.101%
2/17/2026	Farallon Capital Management LLC	5,000	$232K	0.0%	-96.7%	0.009%
2/17/2026	Price T Rowe Associates Inc. MD	3,318,698	$153.66M	0.0%	-15.0%	6.179%
2/17/2026	T. Rowe Price Investment Management Inc.	553	$26K	0.0%	-97.8%	0.001%
2/17/2026	Rock Springs Capital Management LP	247,053	$11.44M	0.6%	+59.9%	0.460%
2/17/2026	Quantitative Investment Management LLC	17,581	$814K	0.1%	N/A	0.033%
2/17/2026	Integral Health Asset Management LLC	325,000	$15.05M	0.7%	N/A	0.605%
2/17/2026	California State Teachers Retirement System	40,717	$1.89M	0.0%	+27.5%	0.076%
2/17/2026	Russell Investments Group Ltd.	46,678	$2.16M	0.0%	-50.5%	0.087%
2/17/2026	Atom Investors LP	17,550	$813K	0.1%	N/A	0.033%
2/17/2026	Clark Capital Management Group Inc.	180,250	$8.35M	0.1%	N/A	0.336%
2/17/2026	Granahan Investment Management LLC	137,592	$6.37M	0.3%	+25.9%	0.256%
2/17/2026	State of Wisconsin Investment Board	72,482	$3.36M	0.0%	+80.3%	0.135%
2/17/2026	Avoro Capital Advisors LLC	2,900,000	$134.27M	1.3%	+12.5%	5.399%
2/17/2026	Royal Bank of Canada	9,656	$447K	0.0%	+2,382.3%	0.018%
2/17/2026	Graham Capital Management L.P.	6,630	$307K	0.0%	-59.5%	0.012%
2/17/2026	Magnetar Financial LLC	13,946	$646K	0.0%	N/A	0.026%
2/17/2026	Militia Capital Partners LP	34,980	$1.62M	0.6%	N/A	0.065%
2/17/2026	Polar Capital Holdings Plc	1,136,929	$52.64M	0.2%	-4.5%	2.117%
2/16/2026	Squarepoint Ops LLC	468,654	$21.70M	0.0%	+712.9%	0.873%
2/16/2026	Sofinnova Investments Inc.	12,414	$575K	0.0%	-92.5%	0.023%
2/16/2026	MML Investors Services LLC	4,757	$220K	0.0%	N/A	0.009%
2/16/2026	Barclays PLC	157,685	$7.30M	0.0%	-18.1%	0.294%
2/13/2026	FORA Capital LLC	16,979	$786K	0.1%	N/A	0.032%
2/13/2026	Marshall Wace LLP	6,595	$305K	0.0%	-96.4%	0.012%
2/13/2026	The Manufacturers Life Insurance Company	41,186	$1.91M	0.0%	-50.8%	0.077%
2/13/2026	DLD Asset Management LP	5,000	$232K	0.0%	-83.3%	0.009%
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2/13/2026	AWM Investment Company Inc.	20,000	$926K	0.1%	N/A	0.037%
2/13/2026	Vivo Capital LLC	894,909	$41.43M	2.7%	-60.7%	1.666%
2/13/2026	Schroder Investment Management Group	449,848	$20.82M	0.0%	+60.5%	0.838%
2/13/2026	Rafferty Asset Management LLC	95,597	$4.43M	0.0%	+3.4%	0.178%
2/13/2026	Integrated Wealth Concepts LLC	6,560	$304K	0.0%	N/A	0.012%
2/13/2026	Alyeska Investment Group L.P.	217,500	$10.07M	0.0%	+13.0%	0.405%
2/13/2026	Charles Schwab Investment Management Inc.	401,186	$18.58M	0.0%	+3.0%	0.747%
2/13/2026	Police & Firemen s Retirement System of New Jersey	12,572	$582K	0.0%	+9.0%	0.023%
2/13/2026	State Street Corp	2,649,626	$122.68M	0.0%	+21.9%	4.933%
2/13/2026	Martingale Asset Management L P	5,810	$269K	0.0%	-13.4%	0.011%

SLNO Institutional Ownership - Frequently Asked Questions

During the previous two years, 257 institutional investors and hedge funds held shares of Soleno Therapeutics. The most heavily invested institutionals were Adage Capital Partners GP L.L.C. ($299.59M), Janus Henderson Group PLC ($237.63M), Wellington Management Group LLP ($153.85M), Price T Rowe Associates Inc. MD ($153.66M), Vanguard Group Inc. ($141.70M), Avoro Capital Advisors LLC ($134.27M), and State Street Corp ($122.68M).Learn more on Soleno Therapeutics' institutional investors.

97.42% of Soleno Therapeutics' stock is owned by institutional investors. Learn more on SLNO's institutional investor holdings.

Of the 239 institutional investors that purchased Soleno Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Wellington Management Group LLP ($3.19M), Janus Henderson Group PLC ($2.95M), Avoro Capital Advisors LLC ($1.98M), Adage Capital Partners GP L.L.C. ($1.62M), Assenagon Asset Management S.A. ($1.55M), Invesco Ltd. ($1.49M), and Nantahala Capital Management LLC ($1.33M).

Institutional investors have bought a total of 24,283,468 shares in the last 24 months. This purchase volume represents approximately $1.45B in transactions.

Of the 79 institutional investors that sold Soleno Therapeutics' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: Vivo Capital LLC ($4.16M), Commodore Capital LP ($1.24M), Perceptive Advisors LLC ($1.08M), Adage Capital Partners GP L.L.C. ($816.73K), Capital World Investors ($678.99K), Invesco Ltd. ($625.51K), and Price T Rowe Associates Inc. MD ($584.21K).

Institutional investors have sold a total of 15,781,019 shares in the last 24 months. This volume of shares sold represents approximately $937.25M in transactions.

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This page (NASDAQ:SLNO) was last updated on 6/7/2026 by MarketBeat.com Staff.

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Soleno Therapeutics (SLNO) Institutional Ownership

SLNO Institutional Buying and Selling by Quarter

Soleno Therapeutics Major Shareholders & Ownership History

SLNO Institutional Ownership - Frequently Asked Questions

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Soleno Therapeutics (SLNO) Institutional Ownership

Institutional Ownership Changes (13F Filings) for Soleno Therapeutics (NASDAQ:SLNO)

SLNO Institutional Buying and Selling by Quarter

Soleno Therapeutics Major Shareholders & Ownership History

SLNO Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of SLNO shares?

What percentage of Soleno Therapeutics' stock is owned by institutional investors?

Which institutional investors have been buying Soleno Therapeutics' stock?

How much institutional buying is happening at Soleno Therapeutics?

Which of Soleno Therapeutics' major shareholders have been selling company stock?

How much institutional selling is happening at Soleno Therapeutics?

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