NASDAQ:SPTX Seaport Therapeutics (SPTX) Stock Price, News & Analysis $24.86 +0.57 (+2.35%) As of 09/4/2026 04:00 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsInsider TradesNews and TrendsOwnershipSEC FilingsShort Interest About Seaport Therapeutics Stock (NASDAQ:SPTX) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Seaport Therapeutics alerts:Sign Up Key Stats Today's Range$23.63▼$25.0050-Day Range$18.23▼$27.8452-Week Range$14.85▼$28.38Volume104,337 shsAverage Volume125,018 shsMarket Capitalization$1.33 billionP/E RatioN/ADividend YieldN/APrice Target$37.33Consensus RatingHold Company Overview Seaport Therapeutics Inc. is a clinical-stage therapeutics company focused on inventing and developing new medicines for patients with depression, anxiety and other debilitating neuropsychiatric disorders. Seaport Therapeutics Inc. is based in BOSTON. Read More Seaport Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks65th Percentile Overall ScoreSPTX MarketRank™: Seaport Therapeutics scored higher than 65% of companies evaluated by MarketBeat, and ranked 271st out of 911 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.2 / 5Analyst RatingHold Consensus RatingSeaport Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.36, and is based on no strong buy ratings, 6 buy ratings, 3 hold ratings, and 2 sell ratings.Upside PotentialSeaport Therapeutics has a consensus price target of $37.33, representing about 50.2% upside from its current price of $24.86.Amount of Analyst CoverageSeaport Therapeutics has been the subject of 5 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Seaport Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Seaport Therapeutics are expected to grow in the coming year, from ($4.60) to ($2.95) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Seaport Therapeutics is -2.05, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Seaport Therapeutics is -2.05, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioSeaport Therapeutics has a P/B Ratio of 3.15. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities. Short Interest0.0 / 5Short Interest LevelBearish Percentage of Shares Shorted5.63% of the float of Seaport Therapeutics has been sold short.Short Interest Ratio / Days to CoverSeaport Therapeutics has a short interest ratio ("days to cover") of 25.13, which indicates bearish sentiment.Change versus previous monthShort interest in Seaport Therapeutics has recently increased by 9.24%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldSeaport Therapeutics does not currently pay a dividend.Dividend GrowthSeaport Therapeutics does not have a long track record of dividend growth. News and Social Media3.9 / 5News Sentiment1.22 News SentimentSeaport Therapeutics has a news sentiment score of 1.22. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.77 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 4 news articles for Seaport Therapeutics this week, compared to 2 articles on an average week.Search Interest11 people have searched for SPTX on MarketBeat in the last 30 days. This is an increase of 1,000% compared to the previous 30 days.MarketBeat FollowsOnly 1 people have added Seaport Therapeutics to their MarketBeat watchlist in the last 30 days. This is a decrease of -50% compared to the previous 30 days. Company Ownership2.9 / 5Insider TradingAcquiring Shares Net Insider BuyingOver the last three months, insiders have purchased a net $235,820.00 in company stock, which represents 0.0177% of the company's market cap.Insider Buying vs. Insider SellingIn the past three months, Seaport Therapeutics insiders have bought more of their company's stock than they have sold. Specifically, they have bought $235,820.00 in company stock and sold $0.00 in company stock.Percentage Held by InstitutionsSeaport Therapeutics has minimal institutional ownership at this time.Read more about Seaport Therapeutics' insider trading history. Receive SPTX Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Seaport Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. 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James Altucher says the plan could cut Amazon out of the AI race and disrupt Blue Origin, with a key deadline landing September 25.September 6 at 1:00 AM | Paradigm Press (Ad)Seaport Therapeutics: A Development-Arbitrage Platform With Two Layers Of ValidationAugust 11, 2026 | seekingalpha.comSeaport Therapeutics Reports Second Quarter 2026 Financial Results and Highlights Recent Corporate and Clinical ProgressAugust 3, 2026 | businesswire.comSeaport Therapeutics (SPTX) Stock Forecast & Price TargetJuly 19, 2026 | investing.comSeaport Therapeutics Earnings Estimates, EPS & Revenue | NASDAQ:SPTXJuly 17, 2026 | benzinga.comSeaport Therapeutics, Inc. (SPTX) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 TranscriptJune 10, 2026 | seekingalpha.comSee More Headlines SPTX Stock Analysis - Frequently Asked Questions How have SPTX shares performed this year? Seaport Therapeutics' stock was trading at $19.84 on April 30, 2026. Since then, SPTX shares have increased by 25.3% and is now trading at $24.86. How were Seaport Therapeutics' earnings last quarter? Seaport Therapeutics, Inc. (NASDAQ:SPTX) announced its earnings results on Monday, August, 3rd. The company reported ($1.78) earnings per share (EPS) for the quarter, missing analysts' consensus estimates of ($0.71) by $1.07. When did Seaport Therapeutics IPO? Seaport Therapeutics (SPTX) raised $241 million in an IPO on Friday, May 1st 2026. The company issued 14,160,000 shares at $16.00-$18.00 per share. When does Seaport Therapeutics' lock-up period expire? Seaport Therapeutics's lock-up period expires on Wednesday, October 28th. Seaport Therapeutics had issued 14,160,000 shares in its IPO on May 1st. The total size of the offering was $254,880,000 based on an initial share price of $18.00. After the expiration of Seaport Therapeutics' lock-up period, restrictions preventing company insiders and major shareholders from selling shares in the company will be lifted. Who are Seaport Therapeutics' major shareholders? Seaport Therapeutics' top institutional investors include TRV GP VI LLC (3.85%), Braidwell LP (0.93%), Citadel Advisors LLC (0.36%) and Alyeska Investment Group L.P. (0.14%). Insiders that own company stock include Arch Venture Partners Xii, Llc and Robert J Hombach. View institutional ownership trends. How do I buy shares of Seaport Therapeutics? Shares of SPTX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. Company Calendar Last Earnings8/03/2026Today9/06/2026Citigroup’s Biopharma Back to School Summit 20269/09/2026Fiscal Year End12/31/2026Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Pharmaceuticals Sub-IndustryPharmaceuticals Current SymbolNASDAQ:SPTX CIK2042347 Webwww.seaporttx.com Phone617-807-4062FaxN/AEmployeesN/AYear FoundedN/APrice Target and Rating Average Price Target for Seaport Therapeutics$37.33 High Price Target$50.00 Low Price Target$30.00 Potential Upside/Downside+50.2%Consensus RatingHold Rating Score (0-4)2.36 Research Coverage11 Analysts Profitability EPS (Trailing Twelve Months)N/A Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet IncomeN/A Net MarginsN/A Pretax MarginN/A Return on EquityN/A Return on AssetsN/A Debt Debt-to-Equity RatioN/A Current Ratio18.00 Quick Ratio18.00 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$7.89 per share Price / Book3.15Miscellaneous Outstanding Shares53,530,000Free FloatN/AMarket Cap$1.33 billion OptionableN/A BetaN/A (Almost) Everything You Need To Know About The EV MarketLooking to profit from the electric vehicle mega-trend? 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