| 5/21/2025 | Acadian Asset Management LLC | 3,134,586 | $2.04M | 0.0% | +78.9% | 3.711% | |
| 5/16/2025 | AQR Capital Management LLC | 1,320,917 | $859K | 0.0% | +1,052.8% | 1.566% | |
| 5/15/2025 | Vestal Point Capital LP | 2,600,000 | $1.69M | 0.1% | +1.2% | 3.082% | |
| 5/15/2025 | RA Capital Management L.P. | 4,434,637 | $2.89M | 0.0% | N/A | 5.257% | |
| 5/15/2025 | Velan Capital Investment Management LP | 1,030,000 | $670K | 0.7% | +3,333.3% | 1.221% | |
| 5/15/2025 | State of Wyoming | 94,932 | $62K | 0.0% | N/A | 0.113% | |
| 5/14/2025 | Affinity Asset Advisors LLC | 752,722 | $490K | 0.0% | N/A | 0.892% | |
| 5/12/2025 | Nuveen LLC | 290,897 | $189K | 0.0% | N/A | 0.345% | |
| 5/12/2025 | Invesco Ltd. | 92,139 | $60K | 0.0% | +137.8% | 0.109% | |
| 5/9/2025 | Charles Schwab Investment Management Inc. | 199,901 | $130K | 0.0% | -20.7% | 0.237% | |
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| 4/30/2025 | Cerity Partners LLC | 39,065 | $25K | 0.0% | N/A | 0.046% | |
| 4/28/2025 | Vontobel Holding Ltd. | 50,000 | $33K | 0.0% | +100.0% | 0.059% | |
| 4/17/2025 | Exchange Traded Concepts LLC | 136,623 | $89K | 0.0% | +201.9% | 0.166% | |
| 2/17/2025 | Velan Capital Investment Management LP | 30,000 | $55K | 0.0% | N/A | 0.036% | |
| 2/17/2025 | Vestal Point Capital LP | 2,570,000 | $4.73M | 0.3% | N/A | 3.117% | |
| 2/17/2025 | Two Sigma Investments LP | 316,292 | $582K | 0.0% | -35.7% | 0.384% | |
| 2/17/2025 | Two Sigma Advisers LP | 547,800 | $1.01M | 0.0% | -7.3% | 0.664% | |
| 2/17/2025 | Suvretta Capital Management LLC | 7,462,495 | $13.73M | 0.5% | +3.8% | 9.050% | |
| 2/17/2025 | Shay Capital LLC | 203,601 | $375K | 0.1% | N/A | 0.247% | |
| 2/17/2025 | Sherbrooke Park Advisers LLC | 33,640 | $62K | 0.0% | -73.9% | 0.041% | |
| 2/17/2025 | Point72 Asset Management L.P. | 2,197,538 | $4.04M | 0.0% | -26.7% | 2.665% | |
| 2/17/2025 | ProShare Advisors LLC | 26,961 | $50K | 0.0% | +74.3% | 0.033% | |
| 2/17/2025 | MPM Bioimpact LLC | 2,160,062 | $3.98M | 0.6% | -23.7% | 2.620% | |
| 2/17/2025 | Parkman Healthcare Partners LLC | 1,727,925 | $3.18M | 0.4% | +0.7% | 2.095% | |
| 2/17/2025 | Man Group plc | 132,406 | $244K | 0.0% | -19.2% | 0.161% | |
| 2/17/2025 | Nuveen Asset Management LLC | 1,323,777 | $2.44M | 0.0% | +10.3% | 1.605% | |
| 2/17/2025 | OMERS ADMINISTRATION Corp | 95,150 | $175K | 0.0% | -50.0% | 0.115% | |
| 2/17/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 300,621 | $553K | 0.0% | -11.1% | 0.365% | |
| 2/17/2025 | Millennium Management LLC | 405,618 | $746K | 0.0% | -80.0% | 0.492% | |
| 2/17/2025 | Jacobs Levy Equity Management Inc. | 859,373 | $1.58M | 0.0% | +4.6% | 1.042% | |
| 2/17/2025 | D. E. Shaw & Co. Inc. | 157,683 | $290K | 0.0% | -5.9% | 0.191% | |
| 2/17/2025 | DAFNA Capital Management LLC | 437,079 | $804K | 0.2% | +32.6% | 0.530% | |
| 2/17/2025 | Bridgeway Capital Management LLC | 189,700 | $349K | 0.0% | +91.2% | 0.230% | |
| 2/17/2025 | Bank of America Corp DE | 106,258 | $196K | 0.0% | -17.7% | 0.129% | |
| 2/17/2025 | BNP Paribas Financial Markets | 150,758 | $277K | 0.0% | +82.7% | 0.183% | |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 196,800 | $362K | 0.0% | -30.6% | 0.239% | |
| 2/14/2025 | Northern Trust Corp | 636,920 | $1.17M | 0.0% | +2.3% | 0.772% | |
| 2/14/2025 | Susquehanna Fundamental Investments LLC | 87,810 | $162K | 0.0% | N/A | 0.106% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 2,000,000 | $3.68M | 0.0% | -11.1% | 2.425% | |
| 2/14/2025 | Eversept Partners LP | 694,408 | $1.28M | 0.1% | -62.3% | 0.842% | |
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| 2/14/2025 | Hsbc Holdings PLC | 63,554 | $116K | 0.0% | -22.2% | 0.077% | |
| 2/14/2025 | MetLife Investment Management LLC | 23,390 | $43K | 0.0% | -24.3% | 0.028% | |
| 2/14/2025 | Dimensional Fund Advisors LP | 1,136,457 | $2.09M | 0.0% | +15.9% | 1.378% | |
| 2/13/2025 | XTX Topco Ltd | 21,809 | $40K | 0.0% | -79.1% | 0.026% | |
| 2/13/2025 | Barclays PLC | 158,814 | $293K | 0.0% | -41.8% | 0.193% | |
| 2/13/2025 | Renaissance Technologies LLC | 1,015,211 | $1.87M | 0.0% | +22.6% | 1.231% | |
| 2/13/2025 | Invesco Ltd. | 38,749 | $71K | 0.0% | +54.2% | 0.047% | |
| 2/13/2025 | Aristides Capital LLC | 79,400 | $146K | 0.0% | N/A | 0.096% | |
| 2/13/2025 | Russell Investments Group Ltd. | 99,445 | $183K | 0.0% | -34.2% | 0.121% | |
| 2/13/2025 | Dynamic Technology Lab Private Ltd | 14,309 | $26K | 0.0% | N/A | 0.017% | |
| 2/13/2025 | Wells Fargo & Company MN | 52,738 | $97K | 0.0% | +24.8% | 0.064% | |
| 2/11/2025 | Prudential Financial Inc. | 547,510 | $1.01M | 0.0% | +351.0% | 0.664% | |
| 2/11/2025 | LPL Financial LLC | 362,232 | $667K | 0.0% | +34.2% | 0.439% | |
| 2/11/2025 | Sei Investments Co. | 56,347 | $104K | 0.0% | N/A | 0.068% | |
| 2/11/2025 | American Century Companies Inc. | 93,033 | $171K | 0.0% | +29.1% | 0.113% | |
| 2/10/2025 | Thrivent Financial for Lutherans | 97,096 | $178K | 0.0% | N/A | 0.118% | |
| 2/10/2025 | Connor Clark & Lunn Investment Management Ltd. | 326,317 | $600K | 0.0% | -25.3% | 0.396% | |
| 1/31/2025 | Baillie Gifford & Co. | 48,791 | $90K | 0.0% | -96.8% | 0.059% | |
| 1/30/2025 | Rhumbline Advisers | 126,698 | $233K | 0.0% | +6.1% | 0.154% | |
| 1/30/2025 | Vontobel Holding Ltd. | 25,000 | $46K | 0.0% | +66.7% | 0.030% | |
| 1/24/2025 | China Universal Asset Management Co. Ltd. | 17,484 | $32K | 0.0% | N/A | 0.021% | |
| 1/17/2025 | SG Americas Securities LLC | 40,432 | $74K | 0.0% | +16.6% | 0.049% | |
| 11/20/2024 | Virtu Financial LLC | 22,305 | $77K | 0.0% | N/A | 0.027% | |
| 11/19/2024 | Barclays PLC | 273,019 | $944K | 0.0% | +385.3% | 0.331% | |
| 11/16/2024 | Geode Capital Management LLC | 1,856,956 | $6.43M | 0.0% | +7.7% | 2.266% | |
| 11/15/2024 | Barclays PLC | 273,019 | $944K | 0.0% | +385.3% | 0.333% | |
| 11/15/2024 | XTX Topco Ltd | 104,200 | $361K | 0.0% | +222.0% | 0.127% | |
| 11/15/2024 | Jane Street Group LLC | 108,192 | $374K | 0.0% | +30.7% | 0.132% | |
| 11/15/2024 | State Street Corp | 1,647,162 | $5.70M | 0.0% | +5.2% | 2.010% | |
| 11/15/2024 | Point72 Asset Management L.P. | 2,997,453 | $10.37M | 0.0% | -32.6% | 3.657% | |
| 11/15/2024 | Parkman Healthcare Partners LLC | 1,716,132 | $5.94M | 0.8% | -4.3% | 2.094% | |
| 11/15/2024 | Jacobs Levy Equity Management Inc. | 821,746 | $2.84M | 0.0% | -21.8% | 1.003% | |
| 11/14/2024 | Suvretta Capital Management LLC | 7,187,495 | $24.87M | 0.8% | -6.8% | 8.769% | |
| 11/14/2024 | MetLife Investment Management LLC | 30,898 | $107K | 0.0% | -36.4% | 0.038% | |
| 11/13/2024 | BNP Paribas Financial Markets | 82,524 | $286K | 0.0% | +1,195.1% | 0.101% | |
| 11/13/2024 | FMR LLC | 189,041 | $654K | 0.0% | +24.9% | 0.231% | |
| 11/13/2024 | Bank of Montreal Can | 814,955 | $2.85M | 0.0% | N/A | 0.994% | |
| 11/12/2024 | Charles Schwab Investment Management Inc. | 251,995 | $872K | 0.0% | +16.2% | 0.307% | |
| 11/9/2024 | Intech Investment Management LLC | 26,336 | $91K | 0.0% | N/A | 0.032% | |
| 11/8/2024 | Connor Clark & Lunn Investment Management Ltd. | 437,051 | $1.51M | 0.0% | N/A | 0.533% | |
| 11/6/2024 | Gladius Capital Management LP | 8,084 | $28K | 0.0% | N/A | 0.010% | |
| 11/6/2024 | Cornercap Investment Counsel Inc. | 18,563 | $64K | 0.0% | -47.5% | 0.023% | |
| 11/5/2024 | Baillie Gifford & Co. | 1,519,341 | $5.26M | 0.0% | -17.8% | 1.854% | |
| 10/10/2024 | Exchange Traded Concepts LLC | 45,260 | $157K | 0.0% | -16.5% | 0.055% | |
| 10/3/2024 | SG Americas Securities LLC | 34,662 | $120K | 0.0% | +134.6% | 0.042% | |
| 9/16/2024 | Cubist Systematic Strategies LLC | 16,463 | $48K | 0.0% | -91.5% | 0.020% | |
| 8/19/2024 | Point72 Asset Management L.P. | 4,447,634 | $13.03M | 0.0% | +1,606.1% | 5.427% | |
| 8/16/2024 | Algert Global LLC | 12,829 | $38K | 0.0% | -46.0% | 0.016% | |
| 8/15/2024 | Susquehanna Fundamental Investments LLC | 225,367 | $660K | 0.0% | +78.2% | 0.276% | |
| 8/15/2024 | The Manufacturers Life Insurance Company | 32,943 | $97K | 0.0% | +27.4% | 0.040% | |
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| 8/15/2024 | Millennium Management LLC | 4,361,893 | $12.78M | 0.0% | -7.9% | 5.333% | |
| 8/15/2024 | AQR Capital Management LLC | 283,516 | $831K | 0.0% | +691.5% | 0.347% | |
| 8/14/2024 | Cubist Systematic Strategies LLC | 16,463 | $48K | 0.0% | -91.5% | 0.020% | |
| 8/14/2024 | ProShare Advisors LLC | 16,316 | $48K | 0.0% | +49.1% | 0.020% | |
| 8/12/2024 | XTX Topco Ltd | 32,356 | $95K | 0.0% | -63.6% | 0.040% | |
| 8/12/2024 | Hsbc Holdings PLC | 60,858 | $173K | 0.0% | +9.7% | 0.074% | |
| 8/9/2024 | Renaissance Technologies LLC | 719,497 | $2.11M | 0.0% | +48.1% | 0.880% | |
| 8/9/2024 | Dimensional Fund Advisors LP | 1,085,281 | $3.18M | 0.0% | -17.1% | 1.327% | |
| 8/8/2024 | American Century Companies Inc. | 66,812 | $196K | 0.0% | -9.2% | 0.082% | |
| 8/6/2024 | Acadian Asset Management LLC | 1,574,958 | $4.61M | 0.0% | +30.8% | 1.926% | |
